| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Decheng Capital LLC | 8.32M (17.37%) | 1.23M Increased by +14.84% | Mar 31, 24 |
| 2 | venBio Select Advisor LLC | 5.78M (12.06%) | 5.78M Increased by +100.00% | Mar 31, 24 |
| 3 | RA Capital Management, LLC | 4.91M (10.25%) | 218.59K Increased by +4.45% | Dec 31, 23 |
| 4 | BlackRock Inc | 3.58M (7.47%) | 516.59K Increased by +14.45% | Mar 31, 24 |
| 5 | T. Rowe Price Associates, Inc. | 3.08M (6.43%) | 1.39M Increased by +45.22% | Mar 31, 24 |
| 6 | State Street Corporation | 2.85M (5.94%) | 1.46M Increased by +51.16% | Mar 31, 24 |
| 7 | Vanguard Group Inc | 2.71M (5.66%) | 477.52K Increased by +17.61% | Mar 31, 24 |
| 8 | Cormorant Asset Management, LLC | 2.70M (5.64%) | 150.00K Increased by +5.56% | Mar 31, 24 |
| 9 | Orbimed Advisors, LLC | 2.68M (5.60%) | 145.25K Increased by +5.42% | Mar 31, 24 |
| 10 | COMMODORE CAPITAL LP | 1.38M (2.87%) | -235.00K Decreased by -17.09% | Mar 31, 24 |
| 11 | Octagon Capital Advisors LP | 1.24M (2.59%) | 491.30K Increased by +39.58% | Mar 31, 24 |
| 12 | Artal Group S A | 1.19M (2.49%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 13 | Avidity Partners Management LP | 1.17M (2.45%) | 1.17M Increased by +100.00% | Mar 31, 24 |
| 14 | Great Point Partners LLC | 1.13M (2.36%) | -2.57M Decreased by -228.17% | Mar 31, 24 |
| 15 | Franklin Resources Inc | 1.09M (2.28%) | -127.13K Decreased by -11.63% | Mar 31, 24 |
| 16 | Geode Capital Management, LLC | 910.60K (1.90%) | 146.25K Increased by +16.06% | Mar 31, 24 |
| 17 | Morgan Stanley - Brokerage Accounts | 789.64K (1.65%) | 70.90K Increased by +8.98% | Mar 31, 24 |
| 18 | Adage Capital Partners Gp LLC | 714.59K (1.49%) | 714.59K Increased by +100.00% | Dec 31, 23 |
| 19 | Two Sigma Advisers, LLC | 668.77K (1.40%) | 404.70K Increased by +60.51% | Mar 31, 24 |
| 20 | Ghost Tree Capital, LLC | 664.13K (1.39%) | 316.70K Increased by +47.69% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | SPDR® S&P Biotech ETF | 1.82M (3.80%) | -53.59K Decreased by -2.94% | Apr 30, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 1.55M (3.24%) | -24.38K Decreased by -1.57% | Apr 30, 24 |
| 3 | US Small-Cap Growth II Equity Comp | 1.37M (2.85%) | 260.87K Increased by +19.09% | Mar 31, 24 |
| 4 | T. Rowe Price New Horizons | 1.37M (2.85%) | 260.87K Increased by +19.09% | Mar 31, 24 |
| 5 | iShares Russell 2000 ETF | 895.42K (1.87%) | -7.14K Decreased by -0.80% | Apr 30, 24 |
| 6 | T. Rowe Price Health Sciences | 704.16K (1.47%) | 490.86K Increased by +69.71% | Mar 31, 24 |
| 7 | Vanguard Institutional Extnd Mkt Idx Tr | 671.84K (1.40%) | -5.31K Decreased by -0.79% | Apr 30, 24 |
| 8 | Franklin Biotechnology Discv A(acc)USD | 666.40K (1.39%) | -46.80K Decreased by -7.02% | Apr 30, 24 |
| 9 | Candriam Eqs L Biotech C USD Cap | 415.00K (0.87%) | -75.00K Decreased by -18.07% | Mar 31, 24 |
| 10 | Eventide Healthcare & Life Sciences I | 408.54K (0.85%) | 408.54K Increased by +100.00% | Mar 31, 24 |
| 11 | Franklin Biotechnology Discovery A | 354.37K (0.74%) | -19.10K Decreased by -5.39% | Apr 30, 24 |
| 12 | Fidelity Small Cap Index | 332.93K (0.70%) | 3.40K Increased by +1.02% | Feb 29, 24 |
| 13 | iShares Biotechnology ETF | 330.77K (0.69%) | -2.39K Decreased by -0.72% | Apr 30, 24 |
| 14 | Man GLG Event Driven Alternative IN USD | 314.05K (0.66%) | 314.05K Increased by +100.00% | Apr 30, 24 |
| 15 | Fidelity® Small Cap Index | 308.42K (0.64%) | 9.00K Increased by +2.92% | Oct 31, 23 |
| 16 | T. Rowe Price New Horizons Tr-Z | 266.47K (0.56%) | 90.23K Increased by +33.86% | Mar 31, 24 |
| 17 | Fidelity Extended Market Index | 258.81K (0.54%) | 35.56K Increased by +13.74% | Mar 31, 24 |
| 18 | T. Rowe Price Integrated US Sm Gr Eq | 250.50K (0.52%) | 250.50K Increased by +100.00% | Mar 31, 24 |
| 19 | State St Russell Sm/Mid Cp® Indx NL Cl C | 234.40K (0.49%) | 0.00 Increased by 0.00% | Apr 30, 24 |
| 20 | Fidelity® Select Biotechnology | 220.80K (0.46%) | 98.70K Increased by +44.70% | Nov 30, 23 |