| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Farallon Capital Management, L.L.C. | 5.67M (11.06%) | 13.60K Increased by +0.24% | Dec 31, 24 |
| 2 | Vanguard Group Inc | 5.63M (10.97%) | 85.34K Increased by +1.52% | Dec 31, 24 |
| 3 | Wellington Management Company LLP | 5.20M (10.13%) | -666.57K Decreased by -12.82% | Sep 30, 23 |
| 4 | BlackRock Inc | 5.02M (9.77%) | -5.51K Decreased by -0.11% | Dec 31, 24 |
| 5 | Bellevue Group AG | 3.52M (6.85%) | -220.76K Decreased by -6.28% | Dec 31, 24 |
| 6 | State Street Corporation | 3.14M (6.11%) | 512.51K Increased by +16.33% | Mar 31, 24 |
| 7 | T. Rowe Price Associates, Inc. | 2.42M (4.72%) | -408.98K Decreased by -16.88% | Dec 31, 24 |
| 8 | Armistice Capital, LLC | 2.26M (4.41%) | 57.23K Increased by +2.53% | Dec 31, 24 |
| 9 | State Street Corp | 2.15M (4.19%) | -179.16K Decreased by -8.32% | Dec 31, 24 |
| 10 | Erste Asset Management GmbH | 2.01M (3.92%) | -175.00K Decreased by -8.71% | Dec 31, 24 |
| 11 | First Trust Advisors L.P. | 1.82M (3.54%) | 43.48K Increased by +2.39% | Dec 31, 23 |
| 12 | Macquarie Group Ltd | 1.68M (3.28%) | -5.81K Decreased by -0.34% | Dec 31, 24 |
| 13 | Jefferies Financial Group Inc | 1.50M (2.92%) | 1.50M Increased by +100.00% | Dec 31, 24 |
| 14 | Citadel Advisors Llc | 1.43M (2.79%) | 1.42M Increased by +99.18% | Dec 31, 24 |
| 15 | Geode Capital Management, LLC | 1.35M (2.63%) | -7.88K Decreased by -0.58% | Dec 31, 24 |
| 16 | Dimensional Fund Advisors, Inc. | 1.33M (2.59%) | -233.12K Decreased by -17.54% | Dec 31, 24 |
| 17 | Marshall Wace Asset Management Ltd | 1.26M (2.46%) | 129.55K Increased by +10.26% | Sep 30, 24 |
| 18 | Goldman Sachs Group Inc | 1.22M (2.37%) | 410.44K Increased by +33.76% | Dec 31, 23 |
| 19 | Morgan Stanley - Brokerage Accounts | 1.19M (2.32%) | -1.17M Decreased by -97.82% | Jun 30, 24 |
| 20 | Bvf Inc | 1.07M (2.09%) | -116.35K Decreased by -10.84% | Dec 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Health Care Inv | 5.15M (10.03%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 2 | BB Biotech AG Ord | 3.52M (6.85%) | -220.76K Decreased by -6.28% | Dec 31, 24 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 1.80M (3.51%) | 6.89K Increased by +0.38% | Mar 31, 25 |
| 4 | Vanguard US Total Market Shares ETF | 1.79M (3.48%) | 2.35K Increased by +0.13% | Sep 30, 24 |
| 5 | First Trust NYSE Arca Biotech ETF | 1.76M (3.44%) | -143.00 Decreased by -0.01% | Dec 28, 23 |
| 6 | Delaware US Small Cap Core Equity (SMA) | 1.61M (3.14%) | -18.86K Decreased by -1.17% | Mar 31, 24 |
| 7 | Macquarie US Small Cap Core Equity | 1.61M (3.14%) | -18.86K Decreased by -1.17% | Mar 31, 24 |
| 8 | Macquarie Small Cap Core I | 1.52M (2.95%) | 43.09K Increased by +2.84% | Mar 31, 25 |
| 9 | Vanguard Small Cap Index | 1.43M (2.78%) | -27.82K Decreased by -1.95% | Mar 31, 25 |
| 10 | iShares Russell 2000 ETF | 1.39M (2.72%) | -11.33K Decreased by -0.81% | Apr 29, 25 |
| 11 | Delaware Small Cap Core I | 1.38M (2.69%) | 0.00 Increased by 0.00% | Oct 31, 24 |
| 12 | SPDR® S&P Biotech ETF | 1.12M (2.17%) | -19.57K Decreased by -1.75% | Apr 30, 25 |
| 13 | T. Rowe Price Health Sciences | 1.06M (2.06%) | -56.53K Decreased by -5.35% | Mar 31, 25 |
| 14 | Polar Capital Biotech S Inc | 1.00M (1.95%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 15 | Vanguard Institutional Extnd Mkt Idx Tr | 891.37K (1.74%) | 20.84K Increased by +2.34% | Mar 31, 25 |
| 16 | DWS Vermögensbildungsfonds I LD | 805.52K (1.57%) | -5.00 Decreased by -0.00% | Mar 31, 25 |
| 17 | Vanguard Small Cap Growth Index Inv | 799.55K (1.56%) | -16.84K Decreased by -2.11% | Mar 31, 25 |
| 18 | T. Rowe Price Integrated US SmCapGrEq | 678.36K (1.32%) | 339.18K Increased by +50.00% | Dec 31, 24 |
| 19 | Fidelity Small Cap Index | 561.03K (1.09%) | 3.49K Increased by +0.62% | Feb 28, 25 |
| 20 | BNP Paribas Health Cr Innovtr Cl Cap | 545.01K (1.06%) | -15.00 Decreased by -0.00% | Mar 31, 25 |