| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Group Inc | 5.59M (10.53%) | -10.52K Decreased by -0.19% | Dec 31, 25 |
| 2 | BlackRock Inc | 5.24M (9.85%) | 689.69K Increased by +13.17% | Dec 31, 25 |
| 3 | Wellington Management Company LLP | 5.20M (9.79%) | -666.57K Decreased by -12.82% | Sep 30, 23 |
| 4 | Farallon Capital Management, L.L.C. | 5.16M (9.71%) | -621.56K Decreased by -12.05% | Dec 31, 25 |
| 5 | Bellevue Group AG | 3.59M (6.76%) | 75.00K Increased by +2.09% | Jun 30, 25 |
| 6 | State Street Corporation | 3.14M (5.91%) | 512.51K Increased by +16.33% | Mar 31, 24 |
| 7 | State Street Corp | 3.11M (5.85%) | 845.43K Increased by +27.20% | Dec 31, 25 |
| 8 | Armistice Capital, LLC | 3.04M (5.71%) | 2.27M Increased by +74.84% | Dec 31, 25 |
| 9 | Erste Asset Management GmbH | 2.80M (5.28%) | 40.00K Increased by +1.43% | Dec 31, 25 |
| 10 | Lynx1 Capital Management, LP | 2.61M (4.92%) | 2.53M Increased by +96.95% | Mar 31, 26 |
| 11 | COMMODORE CAPITAL LP | 2.34M (4.40%) | 13.29K Increased by +0.57% | Sep 30, 25 |
| 12 | Macquarie Group Ltd | 1.96M (3.69%) | 57.51K Increased by +2.94% | Sep 30, 25 |
| 13 | D. E. Shaw & Co LP | 1.84M (3.46%) | 1.47M Increased by +79.98% | Dec 31, 25 |
| 14 | First Trust Advisors L.P. | 1.82M (3.42%) | 43.48K Increased by +2.39% | Dec 31, 23 |
| 15 | Delaware Management Holdings Inc | 1.70M (3.20%) | 1.70M Increased by +100.00% | Dec 31, 25 |
| 16 | T. Rowe Price Associates, Inc. | 1.66M (3.12%) | -617.31K Decreased by -37.26% | Sep 30, 25 |
| 17 | Jefferies Financial Group Inc | 1.50M (2.82%) | 1.50M Increased by +100.00% | Dec 31, 24 |
| 18 | Geode Capital Management, LLC | 1.41M (2.66%) | -2.78K Decreased by -0.20% | Dec 31, 25 |
| 19 | Citadel Advisors Llc | 1.35M (2.54%) | 856.99K Increased by +63.53% | Dec 31, 25 |
| 20 | MPM Oncology Impact Management LP | 1.30M (2.45%) | 1.30M Increased by +100.00% | Dec 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Health Care Inv | 5.15M (9.69%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 2 | BB Biotech AG Ord | 3.71M (6.99%) | 124.59K Increased by +3.35% | Sep 30, 25 |
| 3 | State Street® SPDR® S&P® Biotech ETF | 2.16M (4.06%) | -15.32K Decreased by -0.71% | Apr 30, 26 |
| 4 | Vanguard Total Stock Mkt Idx Inv | 1.88M (3.53%) | 19.74K Increased by +1.05% | Mar 31, 26 |
| 5 | Vanguard US Total Market Shares ETF | 1.79M (3.36%) | 2.35K Increased by +0.13% | Sep 30, 24 |
| 6 | First Trust NYSE Arca Biotech ETF | 1.76M (3.32%) | -143.00 Decreased by -0.01% | Dec 28, 23 |
| 7 | Delaware US Small Cap Core Equity (SMA) | 1.61M (3.03%) | -18.86K Decreased by -1.17% | Mar 31, 24 |
| 8 | Macquarie US Small Cap Core Equity | 1.61M (3.03%) | -18.86K Decreased by -1.17% | Mar 31, 24 |
| 9 | Macquarie Small Cap Core I | 1.43M (2.69%) | -107.41K Decreased by -7.51% | Jul 31, 25 |
| 10 | Delaware Small Cap Core I | 1.38M (2.60%) | 0.00 Increased by 0.00% | Oct 31, 24 |
| 11 | Vanguard Small Cap Index | 1.35M (2.54%) | 27.64K Increased by +2.05% | Mar 31, 26 |
| 12 | iShares Russell 2000 ETF | 1.33M (2.50%) | 11.19K Increased by +0.84% | Apr 30, 26 |
| 13 | Nomura Small Cap Core I | 1.18M (2.23%) | -37.63K Decreased by -3.18% | Mar 31, 26 |
| 14 | Nomura US Small Cap Core Equity | 1.18M (2.23%) | 397.81K Increased by +33.65% | Mar 31, 26 |
| 15 | Polar Capital Biotech S Inc | 1.00M (1.88%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 16 | DWS Vermögensbildungsfonds I LD | 805.52K (1.52%) | 3.00 Increased by +0.00% | Jul 31, 25 |
| 17 | BNP Paribas US Small Cap ClassicC | 790.30K (1.49%) | 22.79K Increased by +2.88% | Mar 31, 26 |
| 18 | Vanguard Small Cap Growth Index Inv | 755.78K (1.42%) | 21.62K Increased by +2.86% | Mar 31, 26 |
| 19 | American Funds SMALLCAP World A | 703.87K (1.32%) | 703.87K Increased by +100.00% | Dec 31, 25 |
| 20 | Vanguard Institutional Extnd Mkt Idx Tr | 654.88K (1.23%) | 15.47K Increased by +2.36% | Mar 31, 26 |