| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Farallon Capital Management, L.L.C. | 5.77M (11.68%) | 67.00K Increased by +1.16% | Jun 30, 25 |
| 2 | Vanguard Group Inc | 5.68M (11.51%) | 77.43K Increased by +1.36% | Jun 30, 25 |
| 3 | Wellington Management Company LLP | 5.20M (10.53%) | -666.57K Decreased by -12.82% | Sep 30, 23 |
| 4 | BlackRock Inc | 4.83M (9.79%) | -274.99K Decreased by -5.69% | Jun 30, 25 |
| 5 | Bellevue Group AG | 3.59M (7.27%) | 75.00K Increased by +2.09% | Jun 30, 25 |
| 6 | State Street Corporation | 3.14M (6.36%) | 512.51K Increased by +16.33% | Mar 31, 24 |
| 7 | Erste Asset Management GmbH | 2.33M (4.71%) | 96.59K Increased by +4.15% | Jun 30, 25 |
| 8 | COMMODORE CAPITAL LP | 2.33M (4.71%) | 140.00K Increased by +6.02% | Jun 30, 25 |
| 9 | T. Rowe Price Associates, Inc. | 2.27M (4.61%) | -27.10K Decreased by -1.19% | Jun 30, 25 |
| 10 | State Street Corp | 1.95M (3.95%) | -498.37K Decreased by -25.54% | Jun 30, 25 |
| 11 | Macquarie Group Ltd | 1.90M (3.85%) | 50.05K Increased by +2.63% | Jun 30, 25 |
| 12 | First Trust Advisors L.P. | 1.82M (3.68%) | 43.48K Increased by +2.39% | Dec 31, 23 |
| 13 | Jefferies Financial Group Inc | 1.50M (3.04%) | 1.50M Increased by +100.00% | Dec 31, 24 |
| 14 | Geode Capital Management, LLC | 1.41M (2.85%) | 11.17K Increased by +0.79% | Jun 30, 25 |
| 15 | Marshall Wace Asset Management Ltd | 1.26M (2.56%) | 129.55K Increased by +10.26% | Sep 30, 24 |
| 16 | Goldman Sachs Group Inc | 1.22M (2.46%) | 410.44K Increased by +33.76% | Dec 31, 23 |
| 17 | Morgan Stanley - Brokerage Accounts | 1.19M (2.42%) | -1.17M Decreased by -97.82% | Jun 30, 24 |
| 18 | Armistice Capital, LLC | 1.17M (2.37%) | -880.00K Decreased by -75.34% | Jun 30, 25 |
| 19 | Paradigm Biocapital Advisors LP | 1.14M (2.31%) | 1.14M Increased by +100.00% | Jun 30, 25 |
| 20 | Bank of America Corp | 1.12M (2.27%) | -15.28K Decreased by -1.36% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Health Care Inv | 5.15M (10.43%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 2 | BB Biotech AG Ord | 3.52M (7.12%) | -220.76K Decreased by -6.28% | Dec 31, 24 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 1.81M (3.66%) | -38.53K Decreased by -2.13% | Jul 31, 25 |
| 4 | Vanguard US Total Market Shares ETF | 1.79M (3.62%) | 2.35K Increased by +0.13% | Sep 30, 24 |
| 5 | First Trust NYSE Arca Biotech ETF | 1.76M (3.57%) | -143.00 Decreased by -0.01% | Dec 28, 23 |
| 6 | Delaware US Small Cap Core Equity (SMA) | 1.61M (3.26%) | -18.86K Decreased by -1.17% | Mar 31, 24 |
| 7 | Macquarie US Small Cap Core Equity | 1.61M (3.26%) | -18.86K Decreased by -1.17% | Mar 31, 24 |
| 8 | Macquarie Small Cap Core I | 1.43M (2.90%) | -107.41K Decreased by -7.51% | Jul 31, 25 |
| 9 | Vanguard Small Cap Index | 1.41M (2.85%) | -9.02K Decreased by -0.64% | Jul 31, 25 |
| 10 | Delaware Small Cap Core I | 1.38M (2.79%) | 0.00 Increased by 0.00% | Oct 31, 24 |
| 11 | iShares Russell 2000 ETF | 1.36M (2.76%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 12 | Polar Capital Biotech S Inc | 1.00M (2.03%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 13 | T. Rowe Price Health Sciences | 979.66K (1.98%) | -10.99K Decreased by -1.12% | Jul 31, 25 |
| 14 | DWS Vermögensbildungsfonds I LD | 805.52K (1.63%) | 3.00 Increased by +0.00% | Jul 31, 25 |
| 15 | Vanguard Small Cap Growth Index Inv | 794.01K (1.61%) | -714.00 Decreased by -0.09% | Jul 31, 25 |
| 16 | Vanguard Institutional Extnd Mkt Idx Tr | 621.56K (1.26%) | -273.97K Decreased by -44.08% | Jul 31, 25 |
| 17 | SPDR® S&P Biotech ETF | 601.90K (1.22%) | 1.34K Increased by +0.22% | Aug 31, 25 |
| 18 | BNP Paribas Health Cr Innovtr Cl Cap | 573.57K (1.16%) | -23.96K Decreased by -4.18% | Jul 31, 25 |
| 19 | Fidelity Small Cap Index | 567.08K (1.15%) | -6.96K Decreased by -1.23% | Jun 30, 25 |
| 20 | JPMorgan Small Cap Growth A | 533.56K (1.08%) | -72.70K Decreased by -13.63% | Nov 30, 24 |