| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 7.96M (24.38%) | 1.48M Increased by +18.57% | Dec 31, 24 |
| 2 | Paradigm Biocapital Advisors LP | 4.37M (13.40%) | 371.60K Increased by +8.50% | Dec 31, 24 |
| 3 | BlackRock Inc | 3.85M (11.81%) | -392.67K Decreased by -10.19% | Dec 31, 24 |
| 4 | NEA Management Company, LLC | 3.75M (11.48%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 5 | Perceptive Advisors LLC | 3.48M (10.66%) | -409.78K Decreased by -11.78% | Dec 31, 24 |
| 6 | Vanguard Group Inc | 3.33M (10.21%) | 868.00K Increased by +26.07% | Dec 31, 24 |
| 7 | RA Capital Management, LLC | 2.79M (8.54%) | 935.85K Increased by +33.58% | Dec 31, 24 |
| 8 | SR ONE CAPITAL MANAGEMENT, LP | 2.35M (7.19%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 9 | T. Rowe Price Associates, Inc. | 2.12M (6.50%) | 220.71K Increased by +10.40% | Dec 31, 24 |
| 10 | State Street Corp | 1.78M (5.44%) | 230.43K Increased by +12.98% | Dec 31, 24 |
| 11 | State Street Corporation | 1.77M (5.44%) | -240.41K Decreased by -13.55% | Dec 31, 23 |
| 12 | HHG PLC | 1.56M (4.77%) | -454.86K Decreased by -29.21% | Dec 31, 24 |
| 13 | Cormorant Asset Management, LLC | 1.30M (3.98%) | 50.00K Increased by +3.85% | Dec 31, 24 |
| 14 | Novo A/S | 1.07M (3.29%) | 75.00K Increased by +6.98% | Sep 30, 23 |
| 15 | AJU IB Investment Co Ltd | 1.05M (3.21%) | -333.33K Decreased by -31.82% | Mar 31, 25 |
| 16 | Geode Capital Management, LLC | 979.03K (3.00%) | 4.06K Increased by +0.41% | Dec 31, 24 |
| 17 | Lord, Abbett & Co LLC | 974.83K (2.99%) | 82.98K Increased by +8.51% | Dec 31, 24 |
| 18 | Deep Track Capital, LP | 725.14K (2.22%) | 725.14K Increased by +100.00% | Dec 31, 23 |
| 19 | Goldman Sachs Group Inc | 711.39K (2.18%) | -163.47K Decreased by -22.98% | Dec 31, 23 |
| 20 | T. Rowe Price Investment Management,Inc. | 705.92K (2.16%) | -238.72K Decreased by -33.82% | Dec 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 1.74M (5.35%) | 380.91K Increased by +21.84% | Mar 31, 25 |
| 2 | Fidelity® Select Biotechnology | 1.19M (3.65%) | -167.40K Decreased by -14.04% | Nov 30, 23 |
| 3 | iShares Russell 2000 ETF | 1.15M (3.52%) | -9.96K Decreased by -0.87% | Mar 31, 25 |
| 4 | Fidelity Select Biotechnology | 805.29K (2.47%) | -117.00K Decreased by -14.53% | Feb 28, 25 |
| 5 | T. Rowe Price Health Sciences | 722.84K (2.22%) | -120.95K Decreased by -16.73% | Mar 31, 25 |
| 6 | SPDR® S&P Biotech ETF | 710.19K (2.18%) | -14.20K Decreased by -2.00% | Mar 31, 25 |
| 7 | American Funds SMALLCAP World A | 709.37K (2.17%) | 456.50K Increased by +64.35% | Mar 31, 25 |
| 8 | Fidelity Growth Compy Commingled Pl S | 697.22K (2.14%) | -309.80K Decreased by -44.43% | Feb 28, 25 |
| 9 | Vanguard Small Cap Index | 686.91K (2.11%) | 135.12K Increased by +19.67% | Mar 31, 25 |
| 10 | Fidelity Growth Company Fund | 684.45K (2.10%) | 2.30K Increased by +0.34% | Feb 28, 25 |
| 11 | Fidelity Small Cap Growth | 643.33K (1.97%) | 0.00 Increased by 0.00% | Jan 31, 25 |
| 12 | Fidelity Select Health Care | 600.00K (1.84%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 13 | Vanguard Institutional Extnd Mkt Idx Tr | 593.32K (1.82%) | 5.68K Increased by +0.96% | Mar 31, 25 |
| 14 | T. Rowe Price Small-Cap Stock | 529.30K (1.62%) | 40.49K Increased by +7.65% | Mar 31, 25 |
| 15 | T. Rowe Price US Small-Cap Core Equity | 529.30K (1.62%) | 309.09K Increased by +58.40% | Mar 31, 25 |
| 16 | Janus Henderson Global Life Sciences D | 484.24K (1.48%) | -6.26K Decreased by -1.29% | Sep 30, 24 |
| 17 | T. Rowe Price New Horizons | 461.38K (1.41%) | -6.24K Decreased by -1.35% | Mar 31, 25 |
| 18 | US Small-Cap Growth II Equity Comp | 461.38K (1.41%) | -65.28K Decreased by -14.15% | Mar 31, 25 |
| 19 | UBS: US Equity Small Cap Growth | 444.31K (1.36%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 20 | Lord Abbett Developing Growth A | 435.68K (1.34%) | -73.45K Decreased by -16.86% | Jan 31, 25 |