| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 7.96M (24.41%) | 1.48M Increased by +18.57% | Dec 31, 24 |
| 2 | Paradigm Biocapital Advisors LP | 4.37M (13.41%) | 371.60K Increased by +8.50% | Dec 31, 24 |
| 3 | BlackRock Inc | 3.85M (11.82%) | -392.67K Decreased by -10.19% | Dec 31, 24 |
| 4 | NEA Management Company, LLC | 3.75M (11.49%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 5 | Perceptive Advisors LLC | 3.48M (10.67%) | -409.78K Decreased by -11.78% | Dec 31, 24 |
| 6 | Vanguard Group Inc | 3.33M (10.21%) | 868.00K Increased by +26.07% | Dec 31, 24 |
| 7 | RA Capital Management, LLC | 2.79M (8.55%) | 935.85K Increased by +33.58% | Dec 31, 24 |
| 8 | SR ONE CAPITAL MANAGEMENT, LP | 2.35M (7.20%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 9 | T. Rowe Price Associates, Inc. | 2.12M (6.51%) | 220.71K Increased by +10.40% | Dec 31, 24 |
| 10 | State Street Corp | 1.78M (5.45%) | 230.43K Increased by +12.98% | Dec 31, 24 |
| 11 | State Street Corporation | 1.77M (5.44%) | -240.41K Decreased by -13.55% | Dec 31, 23 |
| 12 | HHG PLC | 1.56M (4.78%) | -454.86K Decreased by -29.21% | Dec 31, 24 |
| 13 | Cormorant Asset Management, LLC | 1.30M (3.99%) | 50.00K Increased by +3.85% | Dec 31, 24 |
| 14 | Novo A/S | 1.07M (3.30%) | 75.00K Increased by +6.98% | Sep 30, 23 |
| 15 | Geode Capital Management, LLC | 979.03K (3.00%) | 4.06K Increased by +0.41% | Dec 31, 24 |
| 16 | Lord, Abbett & Co LLC | 974.83K (2.99%) | 82.98K Increased by +8.51% | Dec 31, 24 |
| 17 | Deep Track Capital, LP | 725.14K (2.22%) | 725.14K Increased by +100.00% | Dec 31, 23 |
| 18 | Goldman Sachs Group Inc | 711.39K (2.18%) | -163.47K Decreased by -22.98% | Dec 31, 23 |
| 19 | T. Rowe Price Investment Management,Inc. | 705.92K (2.17%) | -238.72K Decreased by -33.82% | Dec 31, 24 |
| 20 | Suvretta Capital Management, LLC | 689.95K (2.12%) | -826.30K Decreased by -119.76% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 1.36M (4.18%) | 1.05K Increased by +0.08% | Feb 28, 25 |
| 2 | Fidelity® Select Biotechnology | 1.19M (3.66%) | -167.40K Decreased by -14.04% | Nov 30, 23 |
| 3 | iShares Russell 2000 ETF | 1.15M (3.53%) | -9.96K Decreased by -0.87% | Mar 31, 25 |
| 4 | T. Rowe Price Health Sciences | 843.79K (2.59%) | -20.60K Decreased by -2.44% | Feb 28, 25 |
| 5 | Fidelity Select Biotechnology | 805.29K (2.47%) | -117.00K Decreased by -14.53% | Feb 28, 25 |
| 6 | SPDR® S&P Biotech ETF | 716.73K (2.20%) | -7.67K Decreased by -1.07% | Mar 31, 25 |
| 7 | Fidelity Growth Compy Commingled Pl S | 697.22K (2.14%) | -309.80K Decreased by -44.43% | Feb 28, 25 |
| 8 | Fidelity Growth Company Fund | 684.45K (2.10%) | 2.30K Increased by +0.34% | Feb 28, 25 |
| 9 | Fidelity Small Cap Growth | 643.33K (1.97%) | 0.00 Increased by 0.00% | Jan 31, 25 |
| 10 | Fidelity Select Health Care | 600.00K (1.84%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 11 | Vanguard Institutional Extnd Mkt Idx Tr | 587.64K (1.80%) | 832.00 Increased by +0.14% | Feb 28, 25 |
| 12 | Vanguard Small Cap Index | 551.78K (1.69%) | 441.00 Increased by +0.08% | Feb 28, 25 |
| 13 | US Small-Cap Growth II Equity Comp | 526.65K (1.62%) | 22.16K Increased by +4.21% | Dec 31, 24 |
| 14 | T. Rowe Price Small-Cap Stock | 488.81K (1.50%) | 218.40K Increased by +44.68% | Feb 28, 25 |
| 15 | Janus Henderson Global Life Sciences D | 484.24K (1.49%) | -6.26K Decreased by -1.29% | Sep 30, 24 |
| 16 | T. Rowe Price New Horizons | 467.62K (1.43%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 17 | UBS: US Equity Small Cap Growth | 444.31K (1.36%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 18 | Lord Abbett Developing Growth A | 435.68K (1.34%) | -73.45K Decreased by -16.86% | Jan 31, 25 |
| 19 | Fidelity Small Cap Index | 425.25K (1.30%) | -7.96K Decreased by -1.87% | Jan 31, 25 |
| 20 | Fidelity Growth Compy Commingled Pl O | 422.71K (1.30%) | 354.51K Increased by +83.87% | Mar 31, 24 |