| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 6.30M (19.26%) | -1.65M Decreased by -26.22% | Mar 31, 25 |
| 2 | Paradigm Biocapital Advisors LP | 4.49M (13.72%) | 120.43K Increased by +2.68% | Mar 31, 25 |
| 3 | Vanguard Group Inc | 3.99M (12.18%) | 655.06K Increased by +16.44% | Mar 31, 25 |
| 4 | BlackRock Inc | 3.97M (12.12%) | 113.55K Increased by +2.86% | Mar 31, 25 |
| 5 | NEA Management Company, LLC | 3.75M (11.44%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 6 | RA Capital Management, LLC | 3.04M (9.28%) | 249.20K Increased by +8.21% | Mar 31, 25 |
| 7 | Perceptive Advisors LLC | 2.93M (8.94%) | -552.41K Decreased by -18.88% | Mar 31, 25 |
| 8 | Vestal Point Capital LP | 2.39M (7.29%) | 1.91M Increased by +80.11% | Mar 31, 25 |
| 9 | SR ONE CAPITAL MANAGEMENT, LP | 2.35M (7.17%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 10 | T. Rowe Price Associates, Inc. | 1.84M (5.62%) | -281.70K Decreased by -15.31% | Mar 31, 25 |
| 11 | State Street Corporation | 1.77M (5.42%) | -240.41K Decreased by -13.55% | Dec 31, 23 |
| 12 | State Street Corp | 1.67M (5.09%) | -108.92K Decreased by -6.54% | Mar 31, 25 |
| 13 | T. Rowe Price Investment Management,Inc. | 1.67M (5.09%) | 959.22K Increased by +57.61% | Mar 31, 25 |
| 14 | HHG PLC | 1.51M (4.61%) | -46.60K Decreased by -3.08% | Mar 31, 25 |
| 15 | Novo A/S | 1.07M (3.28%) | 75.00K Increased by +6.98% | Sep 30, 23 |
| 16 | Cormorant Asset Management, LLC | 1.05M (3.21%) | -250.00K Decreased by -23.81% | Mar 31, 25 |
| 17 | AJU IB Investment Co Ltd | 1.05M (3.20%) | -333.33K Decreased by -31.82% | Mar 31, 25 |
| 18 | Geode Capital Management, LLC | 1.02M (3.12%) | 41.51K Increased by +4.07% | Mar 31, 25 |
| 19 | Citadel Advisors Llc | 726.13K (2.22%) | 700.90K Increased by +96.53% | Mar 31, 25 |
| 20 | Deep Track Capital, LP | 725.14K (2.22%) | 725.14K Increased by +100.00% | Dec 31, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 1.76M (5.39%) | 18.66K Increased by +1.06% | Apr 30, 25 |
| 2 | Fidelity® Select Biotechnology | 1.19M (3.64%) | -167.40K Decreased by -14.04% | Nov 30, 23 |
| 3 | iShares Russell 2000 ETF | 1.10M (3.35%) | 0.00 Increased by 0.00% | May 31, 25 |
| 4 | T. Rowe Price Health Sciences | 722.84K (2.21%) | -120.95K Decreased by -16.73% | Mar 31, 25 |
| 5 | American Funds SMALLCAP World A | 709.37K (2.17%) | 456.50K Increased by +64.35% | Mar 31, 25 |
| 6 | Vanguard Small Cap Index | 690.04K (2.11%) | 3.13K Increased by +0.45% | Apr 30, 25 |
| 7 | SPDR® S&P Biotech ETF | 673.27K (2.06%) | 3.98K Increased by +0.59% | May 31, 25 |
| 8 | Fidelity Small Cap Growth | 643.33K (1.97%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 9 | Fidelity Growth Compy Commingled Pl S | 600.62K (1.84%) | -500.00 Decreased by -0.08% | Apr 30, 25 |
| 10 | Fidelity Select Health Care | 600.00K (1.83%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 11 | Vanguard Institutional Extnd Mkt Idx Tr | 599.20K (1.83%) | 5.88K Increased by +0.98% | Apr 30, 25 |
| 12 | Fidelity Select Biotechnology | 598.69K (1.83%) | -206.60K Decreased by -34.51% | Apr 30, 25 |
| 13 | T. Rowe Price Small-Cap Stock | 529.30K (1.62%) | 40.49K Increased by +7.65% | Mar 31, 25 |
| 14 | T. Rowe Price US Small-Cap Core Equity | 529.30K (1.62%) | 309.09K Increased by +58.40% | Mar 31, 25 |
| 15 | Janus Henderson Global Life Sciences D | 484.24K (1.48%) | -6.26K Decreased by -1.29% | Sep 30, 24 |
| 16 | Fidelity Growth Company Fund | 478.35K (1.46%) | -55.80K Decreased by -11.67% | Apr 30, 25 |
| 17 | T. Rowe Price New Horizons | 461.38K (1.41%) | -6.24K Decreased by -1.35% | Mar 31, 25 |
| 18 | US Small-Cap Growth II Equity Comp | 461.38K (1.41%) | -65.28K Decreased by -14.15% | Mar 31, 25 |
| 19 | UBS: US Equity Small Cap Growth | 444.31K (1.36%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 20 | Fidelity Small Cap Index | 437.01K (1.34%) | 9.48K Increased by +2.17% | Mar 31, 25 |