| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Bvf Inc | 19.52M (48.58%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | BlackRock Inc | 2.21M (5.51%) | -461.79K Decreased by -20.87% | Dec 31, 24 |
| 3 | Redmile Group, LLC | 1.03M (2.57%) | -659.87K Decreased by -63.80% | Dec 31, 24 |
| 4 | Wells Fargo & Co | 995.64K (2.48%) | -112.40K Decreased by -11.29% | Dec 31, 24 |
| 5 | Junked Platinum Investment Management Ltd | 952.07K (2.37%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 6 | Avidity Partners Management LP | 825.00K (2.05%) | -3.65M Decreased by -441.82% | Jun 30, 24 |
| 7 | Renaissance Technologies Corp | 740.20K (1.84%) | 94.19K Increased by +12.73% | Dec 31, 24 |
| 8 | StemPoint Capital LP | 434.59K (1.08%) | 434.59K Increased by +100.00% | Dec 31, 23 |
| 9 | Northern Trust Corp | 403.03K (1.00%) | 403.03K Increased by +100.00% | Dec 31, 24 |
| 10 | Deutsche Bank AG | 253.38K (0.63%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 11 | Assenagon Asset Management SA | 223.88K (0.56%) | -215.85K Decreased by -96.41% | Sep 30, 24 |
| 12 | Morgan Stanley - Brokerage Accounts | 166.56K (0.41%) | 101.61K Increased by +61.01% | Dec 31, 24 |
| 13 | Dimensional Fund Advisors, Inc. | 131.41K (0.33%) | 74.36K Increased by +56.58% | Dec 31, 24 |
| 14 | Handelsbanken Fonder AB | 130.00K (0.32%) | -20.00K Decreased by -15.38% | Mar 31, 25 |
| 15 | Millennium Management LLC | 119.04K (0.30%) | -47.10K Decreased by -39.57% | Dec 31, 24 |
| 16 | LANDSCAPE CAPITAL MANAGEMENT,LLC | 117.42K (0.29%) | 117.42K Increased by +100.00% | Mar 31, 24 |
| 17 | Eversept Partners, LLC | 99.31K (0.25%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 18 | SCOGGIN LLC | 84.40K (0.21%) | 84.40K Increased by +100.00% | Mar 31, 24 |
| 19 | ALPS Advisors Inc | 76.63K (0.19%) | -746.00 Decreased by -0.97% | Sep 30, 24 |
| 20 | Susquehanna International Group, LLP | 71.49K (0.18%) | -3.88K Decreased by -5.43% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Health Sciences Term Trust | 628.83K (1.56%) | -152.86K Decreased by -24.31% | Dec 31, 24 |
| 2 | iShares Biotechnology ETF | 378.40K (0.94%) | 866.00 Increased by +0.23% | Apr 30, 25 |
| 3 | BlackRock Health Sciences Opps Inv A | 358.30K (0.89%) | -95.03K Decreased by -26.52% | Mar 31, 25 |
| 4 | DWS ESG Biotech LC | 253.39K (0.63%) | 11.00 Increased by +0.00% | Mar 31, 25 |
| 5 | Handelsbanken Europa Småbolag (A1 SEK) | 170.00K (0.42%) | -60.00K Decreased by -35.29% | Mar 31, 25 |
| 6 | Monega ARIAD Innovation R | 130.00K (0.32%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 7 | ALPS Medical Breakthroughs ETF | 79.77K (0.20%) | 628.00 Increased by +0.79% | Nov 29, 24 |
| 8 | Fidelity Nasdaq Composite Index | 64.09K (0.16%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 9 | BlackRock Health Sciences | 62.90K (0.16%) | -15.28K Decreased by -24.29% | Dec 31, 24 |
| 10 | Blackrock Health Sciences Trust | 62.90K (0.16%) | -15.28K Decreased by -24.29% | Dec 31, 24 |
| 11 | iShares Nasdaq US Biotech ETF USD Acc | 46.65K (0.12%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 12 | DFA US Targeted Value I | 29.85K (0.07%) | 26.34K Increased by +88.24% | Mar 31, 25 |
| 13 | Fidelity Select Biotechnology | 27.20K (0.07%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 14 | Top Class Healthcare FI | 27.00K (0.07%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 15 | China Universal NASDAQ Bio-Tch ETF(QDII) | 20.97K (0.05%) | 9.35K Increased by +44.58% | Dec 31, 24 |
| 16 | Pacific Select Health Sciences I | 17.65K (0.04%) | -4.62K Decreased by -26.18% | Mar 31, 25 |
| 17 | DFA US Core Equity 2 I | 17.30K (0.04%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 18 | Acadian All Ctry Wld ex US SCap Eq CL A | 15.88K (0.04%) | 0.00 Increased by 0.00% | Mar 4, 25 |
| 19 | Acadian All Ctry Wld ex US SCap Eq CL B | 15.88K (0.04%) | 0.00 Increased by 0.00% | Mar 4, 25 |
| 20 | DFA US Vector Equity I | 15.82K (0.04%) | 0.00 Increased by 0.00% | Mar 31, 25 |