| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Bvf Inc | 19.82M (49.48%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 2 | Redmile Group, LLC | 1.03M (2.58%) | -659.87K Decreased by -63.80% | Dec 31, 24 |
| 3 | Wells Fargo & Co | 1.02M (2.56%) | 26.99K Increased by +2.63% | Jun 30, 25 |
| 4 | Renaissance Technologies Corp | 828.32K (2.07%) | 24.85K Increased by +3.00% | Jun 30, 25 |
| 5 | Avidity Partners Management LP | 825.00K (2.06%) | -3.65M Decreased by -441.82% | Jun 30, 24 |
| 6 | Junked Platinum Investment Management Ltd | 739.34K (1.85%) | -212.73K Decreased by -28.77% | Mar 31, 25 |
| 7 | StemPoint Capital LP | 434.59K (1.08%) | 434.59K Increased by +100.00% | Dec 31, 23 |
| 8 | BlackRock Inc | 411.31K (1.03%) | -745.28K Decreased by -181.20% | Jun 30, 25 |
| 9 | Northern Trust Corp | 381.35K (0.95%) | 4.27K Increased by +1.12% | Jun 30, 25 |
| 10 | Acadian Asset Management LLC | 371.18K (0.93%) | 371.18K Increased by +100.00% | Mar 31, 25 |
| 11 | Millennium Management LLC | 291.53K (0.73%) | 78.78K Increased by +27.02% | Jun 30, 25 |
| 12 | Deutsche Bank AG | 253.38K (0.63%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 13 | Assenagon Asset Management SA | 223.88K (0.56%) | -215.85K Decreased by -96.41% | Sep 30, 24 |
| 14 | Dimensional Fund Advisors, Inc. | 198.69K (0.50%) | -38.87K Decreased by -19.56% | Jun 30, 25 |
| 15 | Citadel Advisors Llc | 146.00K (0.36%) | -5.46K Decreased by -3.74% | Jun 30, 25 |
| 16 | Marshall Wace Asset Management Ltd | 135.84K (0.34%) | -76.34K Decreased by -56.20% | Jun 30, 25 |
| 17 | LANDSCAPE CAPITAL MANAGEMENT,LLC | 117.42K (0.29%) | 117.42K Increased by +100.00% | Mar 31, 24 |
| 18 | Handelsbanken Fonder AB | 105.00K (0.26%) | -25.00K Decreased by -23.81% | Jun 30, 25 |
| 19 | Eversept Partners, LLC | 100.75K (0.25%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 20 | SCOGGIN LLC | 84.40K (0.21%) | 84.40K Increased by +100.00% | Mar 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | iShares Biotechnology ETF | 369.80K (0.92%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 2 | BlackRock Health Sciences Term Trust | 258.71K (0.65%) | -370.12K Decreased by -143.06% | Mar 31, 25 |
| 3 | DWS ESG Biotech LC | 253.39K (0.63%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 4 | Monega ARIAD Innovation R | 130.00K (0.32%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 5 | BlackRock Health Sciences Opps Inv A | 115.87K (0.29%) | -242.44K Decreased by -209.24% | Apr 30, 25 |
| 6 | ALPS Medical Breakthroughs ETF | 79.77K (0.20%) | 628.00 Increased by +0.79% | Nov 29, 24 |
| 7 | Fidelity Nasdaq Composite Index | 63.60K (0.16%) | 260.00 Increased by +0.41% | Jul 31, 25 |
| 8 | BlackRock Health Sciences | 62.90K (0.16%) | -15.28K Decreased by -24.29% | Dec 31, 24 |
| 9 | Blackrock Health Sciences Trust | 62.90K (0.16%) | -15.28K Decreased by -24.29% | Dec 31, 24 |
| 10 | iShares Nasdaq US Biotech ETF USD Acc | 55.18K (0.14%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 11 | DFA US Targeted Value I | 29.85K (0.07%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 12 | Fidelity Select Biotechnology | 27.20K (0.07%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 13 | Top Class Healthcare FI | 27.00K (0.07%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 14 | China Universal NASDAQ Bio-Tch ETF(QDII) | 20.17K (0.05%) | -803.00 Decreased by -3.98% | Jun 30, 25 |
| 15 | Pacific Select Health Sciences I | 17.65K (0.04%) | -4.62K Decreased by -26.18% | Mar 31, 25 |
| 16 | Acadian All Ctry Wld ex US SCap Eq CL A | 15.88K (0.04%) | 0.00 Increased by 0.00% | Mar 4, 25 |
| 17 | Acadian All Ctry Wld ex US SCap Eq CL B | 15.88K (0.04%) | 0.00 Increased by 0.00% | Mar 4, 25 |
| 18 | DFA US Vector Equity I | 15.82K (0.04%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 19 | Dimensional US Targeted Value ETF | 15.80K (0.04%) | 0.00 Increased by 0.00% | Aug 29, 25 |
| 20 | DFA US Small Cap I | 14.87K (0.04%) | 0.00 Increased by 0.00% | Jul 31, 25 |