| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Baker Bros Advisors LP | 42.90M (33.88%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 2 | BlackRock Inc | 20.27M (16.01%) | -383.77K Decreased by -1.89% | Sep 30, 25 |
| 3 | Vanguard Group Inc | 15.15M (11.97%) | -25.41K Decreased by -0.17% | Dec 31, 25 |
| 4 | State Street Corp | 7.26M (5.73%) | 1.08M Increased by +14.85% | Sep 30, 25 |
| 5 | RTW INVESTMENTS, LLC | 7.14M (5.64%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 6 | State Street Corporation | 6.00M (4.74%) | -463.62K Decreased by -7.73% | Mar 31, 24 |
| 7 | Morgan Stanley - Brokerage Accounts | 4.11M (3.25%) | -568.94K Decreased by -13.84% | Jun 30, 25 |
| 8 | T. Rowe Price Associates, Inc. | 4.00M (3.16%) | -1.18M Decreased by -29.48% | Mar 31, 24 |
| 9 | Point72 Asset Management, L.P. | 3.38M (2.67%) | 1.89M Increased by +55.99% | Dec 31, 25 |
| 10 | Geode Capital Management, LLC | 3.24M (2.56%) | 106.81K Increased by +3.30% | Dec 31, 25 |
| 11 | Dimensional Fund Advisors, Inc. | 2.92M (2.31%) | 122.84K Increased by +4.21% | Dec 31, 25 |
| 12 | Palo Alto Investors, LLC | 2.48M (1.96%) | 17.35K Increased by +0.70% | Dec 31, 25 |
| 13 | SG Americas Securities, LLC | 2.48M (1.96%) | 1.97M Increased by +79.18% | Dec 31, 24 |
| 14 | FMR Inc | 2.37M (1.87%) | -1.63M Decreased by -68.73% | Jun 30, 24 |
| 15 | Marshall Wace Asset Management Ltd | 2.36M (1.86%) | 389.17K Increased by +16.50% | Sep 30, 25 |
| 16 | Rockefeller Capital Management L.P. | 2.33M (1.84%) | 1.19M Increased by +51.13% | Jun 30, 25 |
| 17 | First Trust Advisors L.P. | 2.27M (1.79%) | 326.88K Increased by +14.40% | Dec 31, 25 |
| 18 | Goldman Sachs Group Inc | 2.18M (1.72%) | -701.69K Decreased by -32.21% | Mar 31, 25 |
| 19 | Millennium Management LLC | 2.05M (1.62%) | -884.60K Decreased by -43.09% | Sep 30, 24 |
| 20 | BRAIDWELL LP | 2.03M (1.60%) | -346.63K Decreased by -17.06% | Dec 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | iShares Core S&P Small-Cap ETF | 7.52M (5.94%) | 2.79K Increased by +0.04% | Mar 31, 26 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 4.04M (3.19%) | 26.05K Increased by +0.65% | Mar 31, 26 |
| 3 | Vanguard US Total Market Shares ETF | 3.89M (3.07%) | 4.42K Increased by +0.11% | Sep 30, 24 |
| 4 | State Street® SPDR® S&P® Biotech ETF | 3.57M (2.82%) | 209.92K Increased by +5.88% | Mar 31, 26 |
| 5 | iShares Russell 2000 ETF | 3.06M (2.42%) | -25.00K Decreased by -0.82% | Mar 31, 26 |
| 6 | First Trust NYSE Arca Biotech ETF | 3.01M (2.38%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 7 | Vanguard Small Cap Index | 2.95M (2.33%) | 67.55K Increased by +2.29% | Mar 31, 26 |
| 8 | Fidelity® Growth Company | 1.70M (1.34%) | 57.80K Increased by +3.41% | Nov 30, 23 |
| 9 | Vanguard Small Cap Growth Index Inv | 1.65M (1.30%) | 47.65K Increased by +2.89% | Mar 31, 26 |
| 10 | SPDR® S&P Biotech ETF | 1.54M (1.21%) | 3.42K Increased by +0.22% | Aug 31, 25 |
| 11 | T. Rowe Price New Horizons | 1.53M (1.21%) | -176.30K Decreased by -11.53% | Mar 31, 24 |
| 12 | US Small-Cap Growth II Equity Comp | 1.53M (1.21%) | -176.30K Decreased by -11.53% | Mar 31, 24 |
| 13 | Vanguard Institutional Extnd Mkt Idx Tr | 1.40M (1.11%) | 34.45K Increased by +2.46% | Mar 31, 26 |
| 14 | iShares Biotechnology ETF | 1.25M (0.99%) | 2.60K Increased by +0.21% | Mar 31, 26 |
| 15 | Fidelity Small Cap Index | 1.20M (0.95%) | -15.88K Decreased by -1.32% | Jan 31, 26 |
| 16 | T. Rowe Price Health Sciences | 1.20M (0.94%) | -68.81K Decreased by -5.76% | Dec 31, 23 |
| 17 | Fidelity® Small Cap Index | 1.17M (0.92%) | 31.83K Increased by +2.73% | Oct 31, 23 |
| 18 | State Street SPDR Port S&P 600 Sm CpETF | 1.13M (0.89%) | -594.00 Decreased by -0.05% | Mar 31, 26 |
| 19 | SPDR® Portfolio S&P 600™ Sm Cap ETF | 1.10M (0.87%) | 13.13K Increased by +1.19% | Aug 29, 25 |
| 20 | iShares S&P Small-Cap 600 Growth ETF | 1.08M (0.85%) | 0.00 Increased by 0.00% | Mar 31, 26 |