| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Paradigm Biocapital Advisors LP | 4.09M (14.90%) | 215.75K Increased by +5.28% | Sep 30, 24 |
| 2 | BlackRock Inc | 2.94M (10.72%) | 81.46K Increased by +2.77% | Jun 30, 24 |
| 3 | Sofinnova Ventures | 2.19M (8.00%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 4 | Vanguard Group Inc | 2.04M (7.42%) | 78.02K Increased by +3.83% | Sep 30, 24 |
| 5 | Polar Capital Holdings PLC | 1.83M (6.68%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 6 | Cormorant Asset Management, LLC | 1.45M (5.29%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 7 | State Street Corp | 1.21M (4.41%) | 405.17K Increased by +33.49% | Sep 30, 24 |
| 8 | Caligan Partners LP | 1.20M (4.36%) | 613.17K Increased by +51.30% | Sep 30, 24 |
| 9 | Geode Capital Management, LLC | 813.49K (2.97%) | 47.85K Increased by +5.88% | Sep 30, 24 |
| 10 | Logos Global Management LP | 800.00K (2.92%) | 800.00K Increased by +100.00% | Sep 30, 24 |
| 11 | D. E. Shaw & Co LP | 787.54K (2.87%) | -138.92K Decreased by -17.64% | Sep 30, 24 |
| 12 | State Street Corporation | 751.07K (2.74%) | -10.46K Decreased by -1.39% | Mar 31, 24 |
| 13 | Pictet Asset Manangement SA | 687.98K (2.51%) | 28.31K Increased by +4.11% | Sep 30, 24 |
| 14 | Acadian Asset Management LLC | 602.31K (2.20%) | -200.07K Decreased by -33.22% | Mar 31, 24 |
| 15 | BOOTHBAY FUND MANAGEMENT, LLC | 557.43K (2.03%) | 188.07K Increased by +33.74% | Sep 30, 24 |
| 16 | Jacobs Levy Equity Management, Inc. | 530.44K (1.93%) | -34.09K Decreased by -6.43% | Sep 30, 23 |
| 17 | Dimensional Fund Advisors, Inc. | 477.66K (1.74%) | -6.77K Decreased by -1.42% | Sep 30, 24 |
| 18 | Soleus Capital Management, L.P. | 399.98K (1.46%) | -248.00K Decreased by -62.00% | Sep 30, 24 |
| 19 | Point72 Asset Management, L.P. | 358.94K (1.31%) | -1.17M Decreased by -325.44% | Jun 30, 24 |
| 20 | Millennium Management LLC | 349.78K (1.28%) | 67.23K Increased by +19.22% | Jun 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | HBM Healthcare Investments AG Ord | 3.30M (12.03%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 2 | Polar Capital Biotech S Inc | 1.50M (5.47%) | 0.00 Increased by 0.00% | Oct 31, 24 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 1.04M (3.79%) | 0.00 Increased by 0.00% | Oct 31, 24 |
| 4 | iShares Russell 2000 ETF | 1.02M (3.74%) | -2.14K Decreased by -0.21% | Nov 27, 24 |
| 5 | Vanguard Institutional Extnd Mkt Idx Tr | 476.19K (1.74%) | -1.74K Decreased by -0.37% | Oct 31, 24 |
| 6 | Pictet Biotech | 390.64K (1.42%) | 390.64K Increased by +100.00% | Mar 31, 24 |
| 7 | Pictet-Biotech P USD | 390.00K (1.42%) | 3.00K Increased by +0.77% | Aug 31, 24 |
| 8 | SPDR® S&P Biotech ETF | 384.34K (1.40%) | -11.70K Decreased by -3.04% | Nov 27, 24 |
| 9 | Fidelity Small Cap Index | 375.98K (1.37%) | -1.29K Decreased by -0.34% | Sep 30, 24 |
| 10 | Fidelity® Small Cap Index | 356.43K (1.30%) | 9.18K Increased by +2.57% | Oct 31, 23 |
| 11 | iShares Russell 2000 Growth ETF | 330.58K (1.21%) | 0.00 Increased by 0.00% | Nov 27, 24 |
| 12 | Victory Science & Technology | 299.43K (1.09%) | 29.54K Increased by +9.86% | Sep 30, 23 |
| 13 | iShares Biotechnology ETF | 254.63K (0.93%) | 259.00 Increased by +0.10% | Nov 27, 24 |
| 14 | State St Russell Sm/Mid Cp® Indx NL Cl C | 253.39K (0.92%) | -7.60K Decreased by -3.00% | Oct 31, 24 |
| 15 | Pictet-Global Megatrend Sel I USD | 241.64K (0.88%) | 504.00 Increased by +0.21% | Aug 31, 24 |
| 16 | Fidelity Extended Market Index | 195.26K (0.71%) | 13.88K Increased by +7.11% | Sep 30, 24 |
| 17 | iShares Russell 2000 Value ETF | 181.87K (0.66%) | 0.00 Increased by 0.00% | Apr 30, 24 |
| 18 | Vanguard Russell 2000 ETF | 167.84K (0.61%) | -1.05K Decreased by -0.63% | Oct 31, 24 |
| 19 | Schwab US Small-Cap ETF™ | 160.88K (0.59%) | 88.00 Increased by +0.05% | Nov 28, 24 |
| 20 | Fidelity® Extended Market Index | 153.06K (0.56%) | 0.00 Increased by 0.00% | Nov 30, 23 |