| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 11.86M (22.08%) | -92.36K Decreased by -0.78% | Jun 30, 25 |
| 2 | PRIMECAP Management Company | 10.53M (19.61%) | 766.31K Increased by +7.28% | Jun 30, 25 |
| 3 | Vanguard Group Inc | 8.62M (16.06%) | 725.91K Increased by +8.42% | Jun 30, 25 |
| 4 | EcoR1 Capital, LLC | 6.14M (11.44%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 5 | State Street Corporation | 4.24M (7.89%) | 908.59K Increased by +21.45% | Mar 31, 24 |
| 6 | State Street Corp | 3.82M (7.11%) | 133.90K Increased by +3.51% | Jun 30, 25 |
| 7 | T. Rowe Price Associates, Inc. | 3.76M (7.00%) | -170.46K Decreased by -4.53% | Jun 30, 25 |
| 8 | Bvf Inc | 2.74M (5.10%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 9 | FMR Inc | 2.56M (4.77%) | -868.99K Decreased by -33.91% | Dec 31, 23 |
| 10 | Fidelity Management and Research Company | 2.56M (4.77%) | 2.56M Increased by +100.00% | Dec 31, 23 |
| 11 | TCG Crossover Management, LLC | 2.45M (4.57%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 12 | RTW INVESTMENTS, LLC | 2.40M (4.48%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 13 | Dimensional Fund Advisors, Inc. | 1.78M (3.32%) | 43.18K Increased by +2.43% | Jun 30, 25 |
| 14 | Geode Capital Management, LLC | 1.70M (3.17%) | 29.32K Increased by +1.72% | Jun 30, 25 |
| 15 | BRAIDWELL LP | 1.66M (3.08%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 16 | Millennium Management LLC | 1.41M (2.63%) | 593.42K Increased by +41.96% | Sep 30, 24 |
| 17 | T. Rowe Price Investment Management,Inc. | 1.35M (2.52%) | -2.43M Decreased by -179.60% | Dec 31, 23 |
| 18 | Royal Bank of Canada | 1.32M (2.46%) | 1.31M Increased by +99.23% | Jun 30, 25 |
| 19 | Logos Global Management LP | 1.25M (2.33%) | 1.25M Increased by +100.00% | Jun 30, 25 |
| 20 | Darwin Global Management, Ltd. | 1.11M (2.07%) | 1.11M Increased by +100.00% | Mar 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | PRIMECAP Odyssey Aggressive Growth | 6.32M (11.78%) | 383.87K Increased by +6.07% | Jun 30, 25 |
| 2 | iShares Core S&P Small-Cap ETF | 4.23M (7.89%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 3 | PRIMECAP Odyssey Growth | 3.45M (6.43%) | 425.84K Increased by +12.34% | Jun 30, 25 |
| 4 | Vanguard Total Stock Mkt Idx Inv | 2.20M (4.10%) | -48.83K Decreased by -2.22% | Jul 31, 25 |
| 5 | Vanguard US Total Market Shares ETF | 2.17M (4.04%) | 217.00K Increased by +10.00% | Sep 30, 24 |
| 6 | Vanguard Small Cap Index | 1.73M (3.22%) | -10.85K Decreased by -0.63% | Jul 31, 25 |
| 7 | iShares Russell 2000 ETF | 1.70M (3.17%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 8 | US Small-Cap Growth II Equity Comp | 1.44M (2.68%) | -154.25K Decreased by -10.71% | Jun 30, 25 |
| 9 | Fidelity Select Health Care | 1.20M (2.23%) | -192.88K Decreased by -16.07% | Dec 31, 23 |
| 10 | T. Rowe Price New Horizons | 1.15M (2.13%) | -293.56K Decreased by -25.61% | Jul 31, 25 |
| 11 | SPDR® S&P Biotech ETF | 1.10M (2.06%) | 2.46K Increased by +0.22% | Aug 31, 25 |
| 12 | Fidelity Advisor® Health Care I | 1.00M (1.86%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 13 | Vanguard Small Cap Growth Index Inv | 968.36K (1.80%) | -22.15K Decreased by -2.29% | Jul 31, 25 |
| 14 | T. Rowe Price Small-Cap Value | 799.16K (1.49%) | -397.20K Decreased by -49.70% | Dec 31, 23 |
| 15 | Vanguard Institutional Extnd Mkt Idx Tr | 763.30K (1.42%) | -330.74K Decreased by -43.33% | Jul 31, 25 |
| 16 | Fidelity Advisor Health Care I | 750.00K (1.40%) | -146.00K Decreased by -19.47% | Dec 31, 23 |
| 17 | T. Rowe Price Small-Cap Stock | 749.36K (1.40%) | -1.10K Decreased by -0.15% | Sep 30, 23 |
| 18 | T. Rowe Price US Small-Cap Core Equity | 749.36K (1.40%) | -1.10K Decreased by -0.15% | Sep 30, 23 |
| 19 | Vanguard US Opportunities Ins USD Acc | 720.29K (1.34%) | 21.19K Increased by +2.94% | Jun 30, 25 |
| 20 | Fidelity Small Cap Index | 705.71K (1.31%) | 25.69K Increased by +3.64% | Jun 30, 25 |