| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 12.20M (19.17%) | 1.17M Increased by +9.62% | Dec 31, 24 |
| 2 | PRIMECAP Management Company | 8.98M (14.11%) | -152.76K Decreased by -1.70% | Dec 31, 24 |
| 3 | Vanguard Group Inc | 8.02M (12.59%) | 418.04K Increased by +5.21% | Dec 31, 24 |
| 4 | EcoR1 Capital, LLC | 6.14M (9.65%) | 814.35K Increased by +13.25% | Dec 31, 24 |
| 5 | State Street Corporation | 4.24M (6.65%) | 908.59K Increased by +21.45% | Mar 31, 24 |
| 6 | T. Rowe Price Associates, Inc. | 4.04M (6.34%) | 107.35K Increased by +2.66% | Dec 31, 24 |
| 7 | State Street Corp | 3.20M (5.03%) | 81.62K Increased by +2.55% | Dec 31, 24 |
| 8 | Logos Global Management LP | 3.00M (4.71%) | 2.35M Increased by +78.33% | Jun 30, 24 |
| 9 | FMR Inc | 2.56M (4.03%) | -868.99K Decreased by -33.91% | Dec 31, 23 |
| 10 | Fidelity Management and Research Company | 2.56M (4.03%) | 2.56M Increased by +100.00% | Dec 31, 23 |
| 11 | TCG Crossover Management, LLC | 2.45M (3.85%) | 25.00K Increased by +1.02% | Dec 31, 24 |
| 12 | RTW INVESTMENTS, LLC | 2.40M (3.77%) | 1.83M Increased by +76.07% | Dec 31, 24 |
| 13 | Bvf Inc | 2.29M (3.60%) | 1.44M Increased by +62.86% | Dec 31, 24 |
| 14 | Point72 Asset Management, L.P. | 2.18M (3.42%) | -943.15K Decreased by -43.32% | Dec 31, 24 |
| 15 | Geode Capital Management, LLC | 1.63M (2.57%) | 179.53K Increased by +10.98% | Dec 31, 24 |
| 16 | Dimensional Fund Advisors, Inc. | 1.50M (2.36%) | 102.30K Increased by +6.81% | Dec 31, 24 |
| 17 | Millennium Management LLC | 1.41M (2.22%) | 593.42K Increased by +41.96% | Sep 30, 24 |
| 18 | T. Rowe Price Investment Management,Inc. | 1.35M (2.12%) | -2.43M Decreased by -179.60% | Dec 31, 23 |
| 19 | Darwin Global Management, Ltd. | 1.11M (1.74%) | 1.11M Increased by +100.00% | Mar 31, 24 |
| 20 | Loomis, Sayles & Company LP | 1.09M (1.72%) | 192.08K Increased by +17.58% | Dec 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | PRIMECAP Odyssey Aggressive Growth | 5.83M (9.15%) | -23.46K Decreased by -0.40% | Dec 31, 24 |
| 2 | iShares Core S&P Small-Cap ETF | 4.46M (7.01%) | 2.68K Increased by +0.06% | Feb 26, 25 |
| 3 | PRIMECAP Odyssey Growth | 2.52M (3.97%) | -68.04K Decreased by -2.70% | Dec 31, 24 |
| 4 | Vanguard Total Stock Mkt Idx Inv | 2.20M (3.46%) | 45.06K Increased by +2.05% | Jan 31, 25 |
| 5 | Vanguard Small Cap Index | 1.79M (2.81%) | 3.17K Increased by +0.18% | Jan 31, 25 |
| 6 | iShares Russell 2000 ETF | 1.76M (2.76%) | -34.44K Decreased by -1.96% | Feb 26, 25 |
| 7 | T. Rowe Price New Horizons | 1.62M (2.54%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 8 | US Small-Cap Growth II Equity Comp | 1.62M (2.54%) | -1.39K Decreased by -0.09% | Dec 31, 24 |
| 9 | Fidelity Select Health Care | 1.20M (1.89%) | -192.88K Decreased by -16.07% | Dec 31, 23 |
| 10 | T. Rowe Price Integrated US SmCapGrEq | 1.17M (1.84%) | 700.70K Increased by +59.70% | Dec 31, 24 |
| 11 | Vanguard Institutional Extnd Mkt Idx Tr | 1.09M (1.71%) | 320.00 Increased by +0.03% | Jan 31, 25 |
| 12 | Vanguard Small Cap Growth Index Inv | 1.01M (1.58%) | 182.00 Increased by +0.02% | Jan 31, 25 |
| 13 | Fidelity Advisor® Health Care I | 1.00M (1.57%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 14 | T. Rowe Price Small-Cap Value | 799.16K (1.26%) | -397.20K Decreased by -49.70% | Dec 31, 23 |
| 15 | Fidelity Advisor Health Care I | 750.00K (1.18%) | -146.00K Decreased by -19.47% | Dec 31, 23 |
| 16 | T. Rowe Price Small-Cap Stock | 749.36K (1.18%) | -1.10K Decreased by -0.15% | Sep 30, 23 |
| 17 | T. Rowe Price US Small-Cap Core Equity | 749.36K (1.18%) | -1.10K Decreased by -0.15% | Sep 30, 23 |
| 18 | T. Rowe Price Health Sciences | 675.14K (1.06%) | -1.78K Decreased by -0.26% | Dec 31, 24 |
| 19 | Loomis Sayles Small Cap Growth Instl | 637.76K (1.00%) | 127.09K Increased by +19.93% | Dec 31, 24 |
| 20 | Vanguard US Opportunities Ins USD Acc | 632.77K (0.99%) | -11.41K Decreased by -1.80% | Dec 31, 24 |