| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 12.24M (18.28%) | 15.82K Increased by +0.13% | Jun 30, 25 |
| 2 | BlackRock Inc | 5.71M (8.53%) | -50.47K Decreased by -0.88% | Mar 31, 25 |
| 3 | Deep Track Capital, LP | 5.38M (8.04%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 4 | COMMODORE CAPITAL LP | 4.88M (7.28%) | 1.27M Increased by +26.15% | Jun 30, 25 |
| 5 | Vanguard Group Inc | 4.51M (6.73%) | -54.59K Decreased by -1.21% | Jun 30, 25 |
| 6 | State Street Corporation | 4.49M (6.70%) | 1.78M Increased by +39.66% | Mar 31, 24 |
| 7 | Kynam Capital Management, LP | 4.43M (6.61%) | -272.07K Decreased by -6.14% | Jun 30, 25 |
| 8 | VR Adviser, LLC | 3.88M (5.80%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 9 | Fairmount Funds Management LLC | 3.46M (5.17%) | 14.10K Increased by +0.41% | Jun 30, 25 |
| 10 | T. Rowe Price Associates, Inc. | 2.90M (4.32%) | 1.21M Increased by +41.69% | Jun 30, 25 |
| 11 | State Street Corp | 2.87M (4.28%) | -657.07K Decreased by -22.93% | Mar 31, 25 |
| 12 | TANG CAPITAL MANAGEMENT LLC | 2.84M (4.25%) | 50.00K Increased by +1.76% | Jun 30, 25 |
| 13 | Paradigm Biocapital Advisors LP | 2.74M (4.10%) | 646.50K Increased by +23.58% | Jun 30, 25 |
| 14 | Novo A/S | 2.38M (3.56%) | 129.70K Increased by +5.45% | Jun 30, 25 |
| 15 | Maverick Capital Ltd | 2.26M (3.37%) | 195.74K Increased by +8.67% | Jun 30, 25 |
| 16 | AllianceBernstein L.P. | 2.02M (3.02%) | -265.38K Decreased by -13.13% | Mar 31, 25 |
| 17 | RA Capital Management, LLC | 2.01M (3.00%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 18 | EcoR1 Capital, LLC | 1.96M (2.93%) | 1.96M Increased by +100.00% | Sep 30, 24 |
| 19 | Eversept Partners, LLC | 1.90M (2.84%) | 524.87K Increased by +27.59% | Jun 30, 25 |
| 20 | Baker Bros Advisors LP | 1.74M (2.61%) | 1.74M Increased by +100.00% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Fidelity Select Health Care | 2.68M (4.01%) | 52.20K Increased by +1.95% | Jul 31, 25 |
| 2 | Vanguard US Total Market Shares ETF | 2.24M (3.35%) | 324.50K Increased by +14.47% | Sep 30, 24 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 2.24M (3.34%) | -49.64K Decreased by -2.22% | Jul 31, 25 |
| 4 | Fidelity Advisor Biotechnology I | 1.76M (2.63%) | 12.00K Increased by +0.68% | Jul 31, 25 |
| 5 | iShares Russell 2000 ETF | 1.67M (2.50%) | -18.65K Decreased by -1.11% | Aug 29, 25 |
| 6 | Fidelity Advisor Health Care I | 1.57M (2.34%) | 29.70K Increased by +1.89% | Jul 31, 25 |
| 7 | Fidelity Advisor® Biotechnology I | 1.21M (1.81%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 8 | T. Rowe Price New Horizons | 1.21M (1.81%) | -6.02K Decreased by -0.50% | Jun 30, 25 |
| 9 | US Small-Cap Growth II Equity Comp | 1.21M (1.81%) | 237.23K Increased by +19.61% | Jun 30, 25 |
| 10 | Fidelity Small Cap Growth | 1.05M (1.58%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 11 | FIAM Small Cap Core Composite | 1.01M (1.51%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 12 | SPDR® S&P Biotech ETF | 928.94K (1.39%) | -7.90K Decreased by -0.85% | Aug 29, 25 |
| 13 | Fidelity Select Biotechnology | 901.73K (1.35%) | 34.50K Increased by +3.83% | Jul 31, 25 |
| 14 | AB Small Cap Growth A | 869.99K (1.30%) | -12.97K Decreased by -1.49% | Jul 31, 25 |
| 15 | FIAM Small Cap Core CIT Cl B | 857.10K (1.28%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 16 | Vanguard Institutional Extnd Mkt Idx Tr | 753.52K (1.13%) | -328.82K Decreased by -43.64% | Jul 31, 25 |
| 17 | Polar Capital Biotech S Inc | 750.00K (1.12%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 18 | Loomis Sayles Small Cap Growth Instl | 735.81K (1.10%) | -17.00K Decreased by -2.31% | Jul 31, 25 |
| 19 | Fidelity Series Small Cap Opps | 709.91K (1.06%) | 800.00 Increased by +0.11% | Jun 30, 25 |
| 20 | Fidelity Small Cap Index | 697.17K (1.04%) | -58.26K Decreased by -8.36% | Jun 30, 25 |