| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Caligan Partners LP | 8.99M (464.62%) | 1.56M Increased by +17.38% | Mar 31, 25 |
| 2 | Armistice Capital, LLC | 8.57M (442.64%) | -353.60K Decreased by -4.13% | Mar 31, 25 |
| 3 | venBio Select Advisor LLC | 4.00M (206.66%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 4 | Perceptive Advisors LLC | 3.25M (167.90%) | -3.85M Decreased by -118.46% | Dec 31, 24 |
| 5 | BOOTHBAY FUND MANAGEMENT, LLC | 2.81M (145.04%) | 220.30K Increased by +7.85% | Mar 31, 25 |
| 6 | Vanguard Group Inc | 2.36M (122.00%) | 481.41K Increased by +20.39% | Mar 31, 25 |
| 7 | BlackRock Inc | 1.23M (63.42%) | 37.99K Increased by +3.10% | Mar 31, 25 |
| 8 | Geode Capital Management, LLC | 1.02M (52.62%) | 541.22K Increased by +53.14% | Mar 31, 25 |
| 9 | UBS Group AG | 790.16K (40.82%) | 616.10K Increased by +77.97% | Mar 31, 25 |
| 10 | FMR Inc | 634.31K (32.77%) | -474.44K Decreased by -74.80% | Sep 30, 24 |
| 11 | State Street Corp | 567.05K (29.30%) | 43.93K Increased by +7.75% | Mar 31, 25 |
| 12 | Northern Trust Corp | 434.75K (22.46%) | 217.72K Increased by +50.08% | Mar 31, 25 |
| 13 | State Street Corporation | 412.60K (21.32%) | 23.34K Increased by +5.66% | Mar 31, 24 |
| 14 | Millennium Management LLC | 395.65K (20.44%) | 395.65K Increased by +100.00% | Mar 31, 25 |
| 15 | Sovran Advisors, LLC | 392.16K (20.26%) | -14.89K Decreased by -3.80% | Mar 31, 25 |
| 16 | Heights Capital Management Inc | 351.14K (18.14%) | 351.14K Increased by +100.00% | Dec 31, 24 |
| 17 | Propel Bio Management LLC | 344.94K (17.82%) | -80.00K Decreased by -23.19% | Sep 30, 24 |
| 18 | Qube Research & Technologies | 322.19K (16.65%) | 322.19K Increased by +100.00% | Sep 30, 24 |
| 19 | Rhumbline Advisers | 266.09K (13.75%) | 241.34K Increased by +90.70% | Dec 31, 24 |
| 20 | Renaissance Technologies Corp | 233.30K (12.05%) | 85.34K Increased by +36.58% | Dec 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Fidelity® Select Biotechnology | 1.51M (77.95%) | 4.09K Increased by +0.27% | Nov 30, 23 |
| 2 | Vanguard US Total Market Shares ETF | 815.89K (42.15%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 3 | Fidelity Select Biotechnology | 629.87K (32.54%) | -478.20K Decreased by -75.92% | Sep 30, 24 |
| 4 | iShares Russell 2000 ETF | 520.96K (26.92%) | 0.00 Increased by 0.00% | May 31, 25 |
| 5 | Invesco Dorsey Wright SmallCap Momt ETF | 409.00K (21.13%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 6 | Fidelity Small Cap Index | 385.38K (19.91%) | 0.00 Increased by 0.00% | May 31, 25 |
| 7 | State St Russell Sm/Mid Cp® Indx SL Cl I | 232.80K (12.03%) | 29.00K Increased by +12.46% | May 31, 25 |
| 8 | State St Russell Sm/Mid Cp® Indx NL Cl C | 203.80K (10.53%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 9 | Vanguard Russell 2000 ETF | 201.66K (10.42%) | 1.80K Increased by +0.89% | May 31, 25 |
| 10 | Fidelity® Small Cap Index | 201.15K (10.39%) | 2.11K Increased by +1.05% | Oct 31, 23 |
| 11 | Simplify Propel Opportunities ETF | 200.00K (10.33%) | 0.00 Increased by 0.00% | Oct 31, 24 |
| 12 | iShares Russell 2000 Growth ETF | 190.57K (9.85%) | 0.00 Increased by 0.00% | May 31, 25 |
| 13 | DWS Small Cap Core S | 174.70K (9.03%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 14 | Small Cap Core Equity Composite | 174.70K (9.03%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 15 | Vanguard Total Stock Mkt Idx Inv | 127.02K (6.56%) | -2.78K Decreased by -2.19% | Jul 31, 25 |
| 16 | Fidelity® Extended Market Index | 106.11K (5.48%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 17 | Schwab Small Cap Index | 99.50K (5.14%) | 0.00 Increased by 0.00% | May 31, 25 |
| 18 | NT R2000 Index Fund - NL | 82.90K (4.28%) | 37.60K Increased by +45.36% | Mar 31, 25 |
| 19 | State St Russell Sm Cap® Indx SL Cl I | 77.90K (4.02%) | 0.00 Increased by 0.00% | May 31, 25 |
| 20 | iShares Micro-Cap ETF | 77.29K (3.99%) | 0.00 Increased by 0.00% | May 31, 25 |