| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RA Capital Management, LLC | 39.65M (101.80%) | 16.90M Increased by +42.62% | Dec 31, 24 |
| 2 | Paradigm Biocapital Advisors LP | 6.46M (16.58%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 3 | FMR Inc | 6.42M (16.48%) | -651.48K Decreased by -10.15% | Dec 31, 24 |
| 4 | 5AM Venture Management, LLC | 6.36M (16.34%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 5 | LAURION CAPITAL MANAGEMENT LP | 2.53M (6.48%) | -657.44K Decreased by -26.03% | Jun 30, 24 |
| 6 | Hudson Bay Capital Management LP | 2.47M (6.33%) | 2.47M Increased by +100.00% | Sep 30, 24 |
| 7 | Vanguard Group Inc | 1.94M (4.99%) | -11.46K Decreased by -0.59% | Dec 31, 24 |
| 8 | COWEN AND COMPANY, LLC | 1.22M (3.13%) | 1.22M Increased by +100.00% | Sep 30, 24 |
| 9 | Woodline Partners LP | 1.11M (2.85%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 10 | Johnson & Johnson | 1.07M (2.76%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 11 | Artal Group S A | 1.00M (2.57%) | -1.35M Decreased by -134.74% | Mar 31, 24 |
| 12 | State Street Corporation | 657.71K (1.69%) | 49.70K Increased by +7.56% | Mar 31, 24 |
| 13 | Baker Bros Advisors LP | 633.85K (1.63%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 14 | Sarissa Capital Management LP | 618.00K (1.59%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 15 | Renaissance Technologies Corp | 529.50K (1.36%) | -226.51K Decreased by -42.78% | Dec 31, 24 |
| 16 | BlackRock Inc | 488.36K (1.25%) | 709.00 Increased by +0.15% | Dec 31, 24 |
| 17 | Geode Capital Management, LLC | 422.14K (1.08%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 18 | Goldman Sachs Group Inc | 375.34K (0.96%) | 282.17K Increased by +75.18% | Jun 30, 24 |
| 19 | OUP Management Co., LLC | 374.71K (0.96%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 20 | Ensign Peak Advisors Inc | 329.38K (0.85%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Fidelity Growth Compy Commingled Pl S | 2.17M (5.57%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 2 | Fidelity Growth Compy Commingled Pl O | 2.12M (5.44%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 3 | Fidelity® Growth Company | 1.43M (3.68%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 4 | Fidelity Growth Company Fund | 1.41M (3.63%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 5 | Vanguard Total Stock Mkt Idx Inv | 1.39M (3.56%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 6 | Vanguard US Total Market Shares ETF | 1.39M (3.56%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 7 | Fidelity® Select Biotechnology | 1.11M (2.86%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 8 | iShares Russell 2000 ETF | 776.40K (1.99%) | -6.20K Decreased by -0.80% | Apr 30, 24 |
| 9 | Fidelity VIP Growth Initial | 618.39K (1.59%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 10 | VIP Growth Initial | 618.39K (1.59%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 11 | Fidelity Select Biotechnology | 614.60K (1.58%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 12 | Fidelity Capital Appreciation | 610.40K (1.57%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 13 | Fidelity® Capital Appreciation | 610.40K (1.57%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 14 | Fidelity® Growth Company K6 | 603.64K (1.55%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 15 | Vanguard Institutional Extnd Mkt Idx Tr | 519.63K (1.33%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 16 | Fidelity Growth Company K6 | 481.91K (1.24%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 17 | Fidelity Advisor® Equity Growth I | 474.94K (1.22%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 18 | Fidelity Advisor Equity Growth I | 474.17K (1.22%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 19 | Fidelity Small Cap Index | 384.43K (0.99%) | 13.14K Increased by +3.42% | Jun 30, 24 |
| 20 | iShares Russell 2000 Value ETF | 383.06K (0.98%) | 0.00 Increased by 0.00% | Apr 30, 24 |