| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | 5AM Venture Management, LLC | 6.36M (18.44%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 2 | TCG Crossover Management, LLC | 5.67M (16.45%) | 5.67M Increased by +100.00% | Mar 31, 26 |
| 3 | RA Capital Management, LLC | 5.40M (15.67%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 4 | FCPM III SERVICES BV | 4.12M (11.94%) | 500.00K Increased by +12.14% | Mar 31, 26 |
| 5 | VR Adviser, LLC | 3.04M (8.82%) | 1.10M Increased by +36.10% | Mar 31, 26 |
| 6 | Frazier Life Sciences Management, L.P. | 2.54M (7.37%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 7 | Hudson Bay Capital Management LP | 2.47M (7.15%) | 2.47M Increased by +100.00% | Sep 30, 24 |
| 8 | Caligan Partners LP | 1.93M (5.58%) | 1000.00K Increased by +51.95% | Mar 31, 26 |
| 9 | Great Point Partners LLC | 1.75M (5.07%) | 379.89K Increased by +21.71% | Mar 31, 26 |
| 10 | Paradigm Biocapital Advisors LP | 1.75M (5.07%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 11 | FMR Inc | 1.54M (4.46%) | -986.50K Decreased by -64.07% | Mar 31, 26 |
| 12 | Vanguard Capital Management, LLC | 1.43M (4.15%) | 1.43M Increased by +100.00% | Mar 31, 26 |
| 13 | COWEN AND COMPANY, LLC | 1.22M (3.54%) | 1.22M Increased by +100.00% | Sep 30, 24 |
| 14 | Marshall Wace Asset Management Ltd | 1.15M (3.34%) | 1.15M Increased by +100.00% | Mar 31, 26 |
| 15 | State Street Corp | 1.12M (3.24%) | 1.03M Increased by +91.86% | Mar 31, 26 |
| 16 | Woodline Partners LP | 1.11M (3.22%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 17 | Artal Group S A | 1.00M (2.90%) | -1.35M Decreased by -134.74% | Mar 31, 24 |
| 18 | NEXTBio Capital Management LP | 999.97K (2.90%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 19 | BlackRock Inc | 794.76K (2.30%) | 329.12K Increased by +41.41% | Mar 31, 26 |
| 20 | Vanguard Group Inc | 770.25K (2.23%) | 665.06K Increased by +86.34% | Dec 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Fidelity Growth Compy Commingled Pl O | 2.12M (6.14%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 2 | Fidelity Growth Compy Commingled Pl S | 1.96M (5.69%) | -207.80K Decreased by -10.58% | Apr 30, 25 |
| 3 | Fidelity® Growth Company | 1.43M (4.15%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 4 | Vanguard US Total Market Shares ETF | 1.39M (4.02%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 5 | Fidelity Growth Company Fund | 1.27M (3.69%) | -140.15K Decreased by -11.00% | Apr 30, 25 |
| 6 | Fidelity Select Biotechnology | 1.19M (3.44%) | -350.40K Decreased by -29.55% | Apr 30, 26 |
| 7 | Fidelity® Select Biotechnology | 1.11M (3.23%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 8 | Vanguard Total Stock Mkt Idx Inv | 1.07M (3.09%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 9 | State Street® SPDR® S&P® Biotech ETF | 1.04M (3.01%) | -6.46K Decreased by -0.62% | May 31, 26 |
| 10 | iShares Russell 2000 ETF | 776.40K (2.25%) | -6.20K Decreased by -0.80% | Apr 30, 24 |
| 11 | Fidelity VIP Growth Initial | 618.39K (1.79%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 12 | VIP Growth Initial | 618.39K (1.79%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 13 | Fidelity Capital Appreciation | 610.40K (1.77%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 14 | Fidelity® Capital Appreciation | 610.40K (1.77%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 15 | Fidelity® Growth Company K6 | 603.64K (1.75%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 16 | Fidelity Advisor® Equity Growth I | 474.94K (1.38%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 17 | Fidelity Advisor Equity Growth I | 474.17K (1.37%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 18 | Fidelity Growth Company K6 | 438.61K (1.27%) | -43.30K Decreased by -9.87% | Apr 30, 25 |
| 19 | Fidelity Small Cap Index | 384.43K (1.11%) | 13.14K Increased by +3.42% | Jun 30, 24 |
| 20 | iShares Russell 2000 Value ETF | 383.06K (1.11%) | 0.00 Increased by 0.00% | Apr 30, 24 |