| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 7.77M (14.44%) | -1.14M Decreased by -14.73% | Dec 31, 25 |
| 2 | Renaissance Technologies Corp | 3.76M (6.99%) | 378.60K Increased by +10.07% | Mar 31, 26 |
| 3 | Vanguard Group Inc | 3.73M (6.93%) | 144.71K Increased by +3.88% | Dec 31, 25 |
| 4 | AIGH Capital Management, LLC | 2.75M (5.11%) | 751.57K Increased by +27.33% | Mar 31, 26 |
| 5 | TANG CAPITAL MANAGEMENT LLC | 2.35M (4.37%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 6 | Pictet Asset Manangement SA | 1.92M (3.57%) | 181.41K Increased by +9.45% | Dec 31, 23 |
| 7 | Acadian Asset Management LLC | 1.80M (3.34%) | 1.73M Increased by +96.53% | Mar 31, 26 |
| 8 | Dimensional Fund Advisors, Inc. | 1.77M (3.29%) | -346.83K Decreased by -19.58% | Mar 31, 26 |
| 9 | Millennium Management LLC | 1.68M (3.12%) | -1.57M Decreased by -93.62% | Dec 31, 25 |
| 10 | Nantahala Capital Management, LLC | 1.59M (2.96%) | -1.59M Decreased by -100.00% | Sep 30, 24 |
| 11 | Geode Capital Management, LLC | 1.39M (2.59%) | -295.00 Decreased by -0.02% | Dec 31, 25 |
| 12 | State Street Corp | 1.26M (2.35%) | -7.54K Decreased by -0.60% | Dec 31, 25 |
| 13 | Bank of America Corp | 1.21M (2.24%) | 1.18M Increased by +97.75% | Mar 31, 24 |
| 14 | State Street Corporation | 1.20M (2.24%) | -24.80K Decreased by -2.06% | Mar 31, 24 |
| 15 | Krensavage Asset Management, LLC | 1.18M (2.19%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 16 | Empire Financial Management Company, LLC | 1.11M (2.06%) | 350.15K Increased by +31.60% | Dec 31, 25 |
| 17 | Two Sigma Advisers, LLC | 1.05M (1.95%) | 140.00K Increased by +13.34% | Dec 31, 25 |
| 18 | Two Sigma Investments LLC | 978.99K (1.82%) | 316.69K Increased by +32.35% | Dec 31, 25 |
| 19 | Citigroup Inc | 880.60K (1.64%) | 484.11K Increased by +54.98% | Jun 30, 25 |
| 20 | Connor Clark & Lunn Inv Mgmt Ltd | 743.55K (1.38%) | -161.00K Decreased by -21.65% | Dec 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | State Street® SPDR® S&P® Biotech ETF | 1.94M (3.61%) | -13.77K Decreased by -0.71% | Apr 30, 26 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 1.76M (3.27%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 3 | Vanguard US Total Market Shares ETF | 1.74M (3.24%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 4 | iShares Russell 2000 ETF | 1.31M (2.44%) | 11.09K Increased by +0.84% | Apr 30, 26 |
| 5 | Pictet Biopharmaceutical Mother | 864.20K (1.61%) | 245.23K Increased by +28.38% | Oct 13, 23 |
| 6 | Vanguard Institutional Extnd Mkt Idx Tr | 665.19K (1.24%) | 13.08K Increased by +1.97% | Mar 31, 26 |
| 7 | Fidelity® Small Cap Index | 578.15K (1.07%) | 52.64K Increased by +9.11% | Oct 31, 23 |
| 8 | PGIM Quant Small Cap value Equity | 557.80K (1.04%) | 159.20K Increased by +28.54% | Dec 31, 23 |
| 9 | PGIM Quant Solutions Small-Cap Val Z | 557.80K (1.04%) | 37.00K Increased by +6.63% | Dec 31, 23 |
| 10 | Fidelity Small Cap Index | 546.07K (1.01%) | 9.22K Increased by +1.69% | Feb 28, 26 |
| 11 | BlackRock Advantage Small Cap Core Instl | 489.96K (0.91%) | -56.99K Decreased by -11.63% | Mar 31, 26 |
| 12 | iShares Russell 2000 Value ETF | 468.05K (0.87%) | 2.52K Increased by +0.54% | Apr 30, 26 |
| 13 | DFA US Targeted Value I | 444.72K (0.83%) | 13.19K Increased by +2.97% | Jul 31, 25 |
| 14 | Federated Hermes MDT SCC Institutional | 430.41K (0.80%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 15 | Federated Hermes MDT Small Cap Core IS | 430.41K (0.80%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 16 | iShares Biotechnology ETF | 399.14K (0.74%) | 2.53K Increased by +0.63% | Apr 30, 26 |
| 17 | PGIM Quant International Small Cap Eq | 398.60K (0.74%) | 398.60K Increased by +100.00% | Sep 30, 23 |
| 18 | Dimensional US Targeted Value ETF | 366.28K (0.68%) | 0.00 Increased by 0.00% | Aug 29, 25 |
| 19 | Russell 2000 Equity Index Fund B | 359.81K (0.67%) | -177.00 Decreased by -0.05% | Dec 31, 25 |
| 20 | Goldman Sachs Small Cp Val Insghts Instl | 351.48K (0.65%) | -155.27K Decreased by -44.18% | Oct 31, 23 |