| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | NEA Management Company, LLC | 13.22M (14.59%) | 1.85M Increased by +14.01% | Jun 30, 25 |
| 2 | Rubric Capital Management LP | 8.53M (9.41%) | 3.99M Increased by +46.80% | Jun 30, 25 |
| 3 | BlackRock Inc | 8.21M (9.05%) | 2.89M Increased by +35.25% | Jun 30, 25 |
| 4 | Vanguard Group Inc | 5.32M (5.87%) | 1.48M Increased by +27.81% | Jun 30, 25 |
| 5 | Fairmount Funds Management LLC | 5.16M (5.70%) | -27.07K Decreased by -0.52% | Sep 30, 23 |
| 6 | Vivo Capital, LLC | 4.49M (4.95%) | 1.00M Increased by +22.28% | Jun 30, 25 |
| 7 | AllianceBernstein L.P. | 4.28M (4.72%) | 4.26M Increased by +99.48% | Jun 30, 25 |
| 8 | Woodline Partners LP | 4.05M (4.46%) | 1.99M Increased by +49.15% | Jun 30, 25 |
| 9 | Siren, L.L.C. | 3.94M (4.35%) | 1.07M Increased by +27.29% | Jun 30, 25 |
| 10 | Octagon Capital Advisors LP | 3.67M (4.05%) | 350.00K Increased by +9.53% | Jun 30, 25 |
| 11 | MPM Oncology Impact Management LP | 3.41M (3.76%) | -21.41K Decreased by -0.63% | Jun 30, 25 |
| 12 | Orbimed Advisors, LLC | 3.31M (3.65%) | 2.19M Increased by +66.15% | Jun 30, 25 |
| 13 | Armistice Capital, LLC | 2.99M (3.30%) | 2.99M Increased by +100.00% | Mar 31, 25 |
| 14 | Affinity Asset Advisors, LLC | 2.53M (2.80%) | 1.28M Increased by +50.67% | Jun 30, 25 |
| 15 | Adage Capital Partners Gp LLC | 2.50M (2.76%) | 2.50M Increased by +100.00% | Dec 31, 24 |
| 16 | Marshall Wace Asset Management Ltd | 2.48M (2.73%) | -76.31K Decreased by -3.08% | Jun 30, 25 |
| 17 | Balyasny Asset Management LLC | 2.35M (2.60%) | 595.78K Increased by +25.31% | Jun 30, 25 |
| 18 | Opaleye Management Inc | 2.32M (2.56%) | -250.49K Decreased by -10.81% | Dec 31, 24 |
| 19 | State Street Corp | 1.83M (2.02%) | 408.41K Increased by +22.28% | Jun 30, 25 |
| 20 | Geode Capital Management, LLC | 1.79M (1.97%) | 171.98K Increased by +9.62% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 3.12M (3.45%) | -69.28K Decreased by -2.22% | Jul 31, 25 |
| 2 | Fidelity Select Biotechnology | 2.16M (2.38%) | 1.80M Increased by +83.49% | Jul 31, 25 |
| 3 | AB Small Cap Growth A | 2.09M (2.31%) | 119.29K Increased by +5.71% | Jul 31, 25 |
| 4 | iShares Russell 2000 ETF | 1.83M (2.02%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 5 | Vanguard US Total Market Shares ETF | 1.78M (1.96%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 6 | Eventide Healthcare & Life Sciences I | 1.38M (1.52%) | 1.38M Increased by +100.00% | Jun 30, 25 |
| 7 | BlackRock Advantage Small Cap Core Instl | 844.90K (0.93%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 8 | Vanguard Institutional Extnd Mkt Idx Tr | 793.99K (0.88%) | -365.90K Decreased by -46.08% | Jul 31, 25 |
| 9 | Fidelity Small Cap Index | 761.49K (0.84%) | 5.37K Increased by +0.70% | Jun 30, 25 |
| 10 | iShares Russell 2000 Growth ETF | 660.91K (0.73%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 11 | Wellington Global Hlthcr Eq USD G Ac | 620.61K (0.68%) | 620.61K Increased by +100.00% | Jul 31, 25 |
| 12 | Principal SmallCap Growth I Instl | 514.18K (0.57%) | 34.82K Increased by +6.77% | Jul 31, 25 |
| 13 | AB US Small Cap Growth Collective Tr W | 506.71K (0.56%) | 8.00K Increased by +1.58% | Jul 31, 25 |
| 14 | Biotech Growth Ord | 492.00K (0.54%) | 0.00 Increased by 0.00% | May 31, 25 |
| 15 | MEDICAL BioHealth EUR Acc | 414.62K (0.46%) | 119.62K Increased by +28.85% | Jun 30, 25 |
| 16 | iShares Biotechnology ETF | 414.50K (0.46%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 17 | Fidelity Extended Market Index | 398.67K (0.44%) | 4.88K Increased by +1.22% | Jul 31, 25 |
| 18 | State St Russell Sm/Mid Cp® Indx SL Cl I | 387.46K (0.43%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 19 | Fidelity® Small Cap Index | 369.71K (0.41%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 20 | Vanguard Russell 2000 ETF | 360.79K (0.40%) | -25.47K Decreased by -7.06% | Jul 31, 25 |