| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | NEA Management Company, LLC | 13.22M (11.22%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 2 | Frazier Life Sciences Management, L.P. | 10.26M (8.71%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 3 | BlackRock Inc | 10.13M (8.59%) | 225.13K Increased by +2.22% | Dec 31, 25 |
| 4 | FMR Inc | 6.50M (5.52%) | 3.20M Increased by +49.23% | Dec 31, 25 |
| 5 | Vanguard Group Inc | 6.43M (5.46%) | 607.67K Increased by +9.44% | Dec 31, 25 |
| 6 | Fairmount Funds Management LLC | 5.16M (4.38%) | -27.07K Decreased by -0.52% | Sep 30, 23 |
| 7 | Vivo Capital, LLC | 5.09M (4.32%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 8 | Marshall Wace Asset Management Ltd | 4.58M (3.89%) | -261.20K Decreased by -5.70% | Dec 31, 25 |
| 9 | Morgan Stanley - Brokerage Accounts | 4.30M (3.65%) | 3.28M Increased by +76.20% | Sep 30, 25 |
| 10 | Woodline Partners LP | 4.05M (3.43%) | 1.99M Increased by +49.15% | Jun 30, 25 |
| 11 | Rubric Capital Management LP | 3.71M (3.15%) | -54.38K Decreased by -1.46% | Mar 31, 26 |
| 12 | Wellington Management Company LLP | 3.40M (2.89%) | 150.10K Increased by +4.41% | Dec 31, 25 |
| 13 | MPM Oncology Impact Management LP | 3.29M (2.79%) | -119.87K Decreased by -3.65% | Dec 31, 25 |
| 14 | Viking Global Investors LP | 3.20M (2.71%) | -1.93M Decreased by -60.35% | Dec 31, 25 |
| 15 | Orbimed Advisors, LLC | 3.19M (2.71%) | -117.70K Decreased by -3.69% | Dec 31, 25 |
| 16 | AllianceBernstein L.P. | 3.08M (2.62%) | -1.21M Decreased by -39.23% | Dec 31, 25 |
| 17 | Armistice Capital, LLC | 2.99M (2.54%) | 2.99M Increased by +100.00% | Mar 31, 25 |
| 18 | Octagon Capital Advisors LP | 2.81M (2.39%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 19 | Eventide Asset Management, LLC | 2.62M (2.23%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 20 | Adage Capital Partners Gp LLC | 2.50M (2.12%) | 2.50M Increased by +100.00% | Dec 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 3.70M (3.14%) | 274.80K Increased by +7.43% | Mar 31, 26 |
| 2 | Eventide Healthcare & Life Sciences I | 2.62M (2.23%) | 1.24M Increased by +47.32% | Dec 31, 25 |
| 3 | Fidelity Select Biotechnology | 2.38M (2.02%) | 90.00K Increased by +3.78% | Mar 31, 26 |
| 4 | iShares Russell 2000 ETF | 2.26M (1.92%) | 19.04K Increased by +0.84% | Apr 30, 26 |
| 5 | Vanguard US Total Market Shares ETF | 1.78M (1.51%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 6 | MEDICAL BioHealth EUR Acc | 1.39M (1.18%) | -1.42K Decreased by -0.10% | Mar 31, 26 |
| 7 | Fidelity Small Cap Growth | 1.29M (1.10%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 8 | AB Small Cap Growth A | 1.25M (1.06%) | -34.89K Decreased by -2.79% | Mar 31, 26 |
| 9 | Vanguard Institutional Extnd Mkt Idx Tr | 1.16M (0.99%) | 26.83K Increased by +2.31% | Mar 31, 26 |
| 10 | Pictet-Biotech P USD | 1.10M (0.94%) | 1.10M Increased by +100.00% | Jan 31, 26 |
| 11 | Fidelity Select Health Care | 1.00M (0.85%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 12 | Biotech Growth Ord | 894.50K (0.76%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 13 | Fidelity Small Cap Index | 888.69K (0.75%) | 10.40K Increased by +1.17% | Feb 28, 26 |
| 14 | Principal SmallCap Growth I Instl | 804.02K (0.68%) | -1.35K Decreased by -0.17% | Mar 31, 26 |
| 15 | iShares Russell 2000 Growth ETF | 781.84K (0.66%) | 2.02K Increased by +0.26% | Apr 30, 26 |
| 16 | Fidelity Growth Compy Commingled Pl S | 682.79K (0.58%) | 161.99K Increased by +23.73% | Mar 31, 26 |
| 17 | Fidelity Small Cap Growth K6 | 643.32K (0.55%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 18 | iShares Biotechnology ETF | 610.99K (0.52%) | 9.46K Increased by +1.55% | Apr 30, 26 |
| 19 | Emerald Growth A | 579.25K (0.49%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 20 | BlackRock Advantage Small Cap Core Instl | 572.21K (0.49%) | -7.04K Decreased by -1.23% | Mar 31, 26 |