| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | TRV GP IV, LLC | 16.86M (42.17%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 2 | TCG Crossover Management, LLC | 10.74M (26.85%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 3 | EcoR1 Capital, LLC | 10.63M (26.59%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 4 | Boxer Capital Management, LLC | 10.38M (25.97%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 5 | FMR Inc | 9.38M (23.46%) | -29.28K Decreased by -0.31% | Sep 30, 24 |
| 6 | Boxer Capital LLC | 8.20M (20.51%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 7 | Nextech Invest AG | 5.53M (13.84%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 8 | Nextech Invest, Ltd. | 5.53M (13.84%) | 5.53M Increased by +100.00% | Mar 31, 25 |
| 9 | Southpoint Capital Advisors LP | 5.00M (12.51%) | -276.70K Decreased by -5.53% | Sep 30, 24 |
| 10 | Farallon Capital Management, L.L.C. | 4.61M (11.53%) | 610.93K Increased by +13.25% | Mar 31, 25 |
| 11 | BlackRock Inc | 4.03M (10.09%) | -346.49K Decreased by -8.59% | Mar 31, 25 |
| 12 | Vanguard Group Inc | 3.88M (9.69%) | -109.68K Decreased by -2.83% | Mar 31, 25 |
| 13 | T. Rowe Price Investment Management,Inc. | 3.31M (8.29%) | -33.10K Decreased by -1.00% | Mar 31, 25 |
| 14 | Balyasny Asset Management LLC | 3.22M (8.05%) | -59.63K Decreased by -1.85% | Mar 31, 25 |
| 15 | Nantahala Capital Management, LLC | 2.99M (7.47%) | 183.57K Increased by +6.14% | Mar 31, 25 |
| 16 | State Street Corporation | 2.87M (7.17%) | 1.89M Increased by +65.84% | Mar 31, 24 |
| 17 | Bain Capital Life Sciences Investors, LLC | 2.71M (6.78%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 18 | Siren, L.L.C. | 2.57M (6.42%) | -38.55K Decreased by -1.50% | Mar 31, 25 |
| 19 | Artal Group S A | 2.52M (6.30%) | 325.00K Increased by +12.90% | Jun 30, 24 |
| 20 | Adage Capital Partners Gp LLC | 2.29M (5.74%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Fidelity Growth Compy Commingled Pl S | 2.42M (6.04%) | 712.74K Increased by +29.51% | Oct 31, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 2.20M (5.51%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 3 | Fidelity Growth Compy Commingled Pl O | 1.69M (4.24%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 4 | T. Rowe Price Small-Cap Value | 1.66M (4.16%) | -358.00 Decreased by -0.02% | Mar 31, 25 |
| 5 | Fidelity Growth Company Fund | 1.53M (3.84%) | 543.72K Increased by +35.45% | Oct 31, 24 |
| 6 | Fidelity® Small Cap Growth | 1.26M (3.16%) | -1.53K Decreased by -0.12% | Oct 31, 23 |
| 7 | Fidelity Small Cap Growth | 1.25M (3.14%) | 0.00 Increased by 0.00% | Oct 31, 24 |
| 8 | T. Rowe Price Small-Cap Stock | 1.19M (2.97%) | 199.50K Increased by +16.82% | Sep 30, 24 |
| 9 | T. Rowe Price US Small-Cap Core Equity | 1.19M (2.97%) | 277.63K Increased by +23.40% | Sep 30, 24 |
| 10 | iShares Russell 2000 ETF | 1.18M (2.96%) | 0.00 Increased by 0.00% | May 31, 25 |
| 11 | SPDR® S&P Biotech ETF | 1.12M (2.81%) | 16.00K Increased by +1.42% | Nov 30, 24 |
| 12 | Fidelity® Growth Company | 1.02M (2.55%) | 52.20K Increased by +5.12% | Nov 30, 23 |
| 13 | Vanguard Institutional Extnd Mkt Idx Tr | 986.39K (2.47%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 14 | T. Rowe Price U.S. SC Value Eq Tr-D | 967.15K (2.42%) | 1.56K Increased by +0.16% | Mar 31, 25 |
| 15 | T. Rowe Price U.S. SC Value Eq Tr-Z | 967.15K (2.42%) | 1.56K Increased by +0.16% | Mar 31, 25 |
| 16 | Fidelity Advisor Biotechnology I | 724.72K (1.81%) | 317.85K Increased by +43.86% | Oct 31, 24 |
| 17 | International Biotechnology Ord | 655.16K (1.64%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 18 | Fidelity Advisor® Biotechnology I | 633.97K (1.59%) | -50.00K Decreased by -7.89% | Nov 30, 23 |
| 19 | T. Rowe Price Instl Small-Cap Stock | 587.45K (1.47%) | 99.70K Increased by +16.97% | Sep 30, 24 |
| 20 | Fidelity Select Biotechnology | 587.40K (1.47%) | 464.31K Increased by +79.05% | Oct 31, 24 |