| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RTW INVESTMENTS, LLC | 13.30M (19.12%) | 11.81M Increased by +88.79% | Mar 31, 26 |
| 2 | Adage Capital Partners Gp LLC | 12.81M (18.42%) | 2.20M Increased by +17.19% | Mar 31, 26 |
| 3 | Boxer Capital Management, LLC | 10.88M (15.64%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 4 | EcoR1 Capital, LLC | 10.63M (15.28%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 5 | TCG Crossover Management, LLC | 10.53M (15.14%) | -2.23M Decreased by -21.19% | Mar 31, 26 |
| 6 | FMR Inc | 9.91M (14.24%) | 7.04M Increased by +71.05% | Mar 31, 26 |
| 7 | Farallon Capital Management, L.L.C. | 9.10M (13.08%) | -3.96M Decreased by -43.57% | Mar 31, 26 |
| 8 | BlackRock Inc | 8.75M (12.58%) | 207.25K Increased by +2.37% | Mar 31, 26 |
| 9 | Boxer Capital LLC | 8.20M (11.79%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 10 | Woodline Partners LP | 8.00M (11.50%) | -2.07M Decreased by -25.90% | Mar 31, 26 |
| 11 | Nextech Invest, Ltd. | 7.27M (10.45%) | 1.73M Increased by +23.84% | Dec 31, 25 |
| 12 | Vanguard Group Inc | 6.75M (9.71%) | 1.70M Increased by +25.17% | Dec 31, 25 |
| 13 | TRV GP IV, LLC | 6.37M (9.16%) | -1.50M Decreased by -23.53% | Mar 31, 26 |
| 14 | Siren, L.L.C. | 5.66M (8.13%) | -2.51M Decreased by -44.34% | Mar 31, 26 |
| 15 | Nextech Invest AG | 5.53M (7.96%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 16 | Vanguard Capital Management, LLC | 5.16M (7.42%) | 5.16M Increased by +100.00% | Mar 31, 26 |
| 17 | The Goldman Sachs Group Inc | 5.08M (7.30%) | 133.98K Increased by +2.64% | Mar 31, 26 |
| 18 | Southpoint Capital Advisors LP | 5.00M (7.19%) | -276.70K Decreased by -5.53% | Sep 30, 24 |
| 19 | State Street Corp | 4.65M (6.69%) | -1.57M Decreased by -33.68% | Mar 31, 26 |
| 20 | Deerfield Management Co | 4.15M (5.96%) | 1.24M Increased by +29.90% | Mar 31, 26 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 3.94M (5.67%) | 10.45K Increased by +0.27% | Apr 30, 26 |
| 2 | Fidelity Growth Compy Commingled Pl S | 2.80M (4.03%) | 633.48K Increased by +22.59% | Apr 30, 26 |
| 3 | iShares Russell 2000 ETF | 2.65M (3.81%) | 24.49K Increased by +0.92% | May 29, 26 |
| 4 | Fidelity Select Biotechnology | 2.34M (3.36%) | -186.20K Decreased by -7.96% | Apr 30, 26 |
| 5 | Fidelity Growth Company Fund | 2.23M (3.21%) | 491.30K Increased by +22.02% | Apr 30, 26 |
| 6 | State Street® SPDR® S&P® Biotech ETF | 2.18M (3.14%) | -13.43K Decreased by -0.61% | May 31, 26 |
| 7 | Fidelity Growth Compy Commingled Pl O | 1.69M (2.43%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 8 | T. Rowe Price Small-Cap Value | 1.54M (2.22%) | -117.06K Decreased by -7.59% | Jul 31, 25 |
| 9 | Fidelity® Small Cap Growth | 1.26M (1.81%) | -1.53K Decreased by -0.12% | Oct 31, 23 |
| 10 | FIAM Small Cap Core Composite | 1.26M (1.81%) | 1.26M Increased by +100.00% | Dec 31, 25 |
| 11 | T. Rowe Price Small-Cap Stock | 1.19M (1.71%) | 199.50K Increased by +16.82% | Sep 30, 24 |
| 12 | T. Rowe Price US Small-Cap Core Equity | 1.19M (1.71%) | 277.63K Increased by +23.40% | Sep 30, 24 |
| 13 | SPDR® S&P Biotech ETF | 1.12M (1.62%) | 16.00K Increased by +1.42% | Nov 30, 24 |
| 14 | Vanguard Institutional Extnd Mkt Idx Tr | 1.11M (1.59%) | 9.23K Increased by +0.83% | Apr 30, 26 |
| 15 | Fidelity Small Cap Index | 1.09M (1.57%) | 48.16K Increased by +4.42% | Mar 31, 26 |
| 16 | Fidelity® Growth Company | 1.02M (1.47%) | 52.20K Increased by +5.12% | Nov 30, 23 |
| 17 | T. Rowe Price U.S. SC Value Eq Tr-D | 971.86K (1.40%) | 4.71K Increased by +0.48% | Jun 30, 25 |
| 18 | T. Rowe Price U.S. SC Value Eq Tr-Z | 967.15K (1.39%) | 1.56K Increased by +0.16% | Mar 31, 25 |
| 19 | iShares Russell 2000 Value ETF | 960.85K (1.38%) | 0.00 Increased by 0.00% | May 29, 26 |
| 20 | Nuveen Quant Small Cap Equity R6 | 820.00K (1.18%) | 820.00K Increased by +100.00% | Jul 31, 25 |