| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Baker Bros Advisors LP | 4.70M (145.71%) | -569.39K Decreased by -12.10% | Sep 30, 23 |
| 2 | Curative Ventures V LLC | 1.90M (58.82%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 3 | Western Standard LLC | 1.80M (55.66%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 4 | Jacobs Levy Equity Management, Inc. | 867.28K (26.86%) | 653.54K Increased by +75.36% | Sep 30, 23 |
| 5 | BML Capital Management LLC | 645.60K (20.00%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 6 | Cpmg Inc | 410.92K (12.73%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 7 | Boxer Capital LLC | 355.50K (11.01%) | 355.50K Increased by +100.00% | Sep 30, 24 |
| 8 | Perceptive Advisors LLC | 345.55K (10.70%) | 345.55K Increased by +100.00% | Sep 30, 24 |
| 9 | Vivo Capital, LLC | 292.74K (9.07%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 10 | Cable Car Capital LLC | 258.10K (7.99%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 11 | Millennium Management LLC | 242.77K (7.52%) | 46.03K Increased by +18.96% | Dec 31, 25 |
| 12 | Siren, L.L.C. | 203.93K (6.32%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 13 | Vanguard Group Inc | 191.06K (5.92%) | 23.25K Increased by +12.17% | Dec 31, 25 |
| 14 | Goldman Sachs Group Inc | 163.26K (5.06%) | 30.83K Increased by +18.88% | Jun 30, 25 |
| 15 | Sectoral Asset Management Inc | 161.38K (5.00%) | 75.16K Increased by +46.57% | Sep 30, 25 |
| 16 | COMMODORE CAPITAL LP | 150.93K (4.67%) | 150.93K Increased by +100.00% | Sep 30, 24 |
| 17 | SUPERSTRING CAPITAL MANAGEMENT LP | 148.02K (4.58%) | 40.47K Increased by +27.34% | Dec 31, 24 |
| 18 | Amvescap Plc. | 145.12K (4.49%) | 145.12K Increased by +100.00% | Sep 30, 24 |
| 19 | IEQ CAPITAL, LLC | 120.00K (3.72%) | 120.00K Increased by +100.00% | Sep 30, 23 |
| 20 | Orbimed Advisors, LLC | 116.78K (3.62%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Fidelity® Extended Market Index | 357.16K (11.06%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 118.99K (3.69%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 3 | Fidelity® Total Market Index | 105.72K (3.27%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 4 | Biotech Growth Ord | 94.51K (2.93%) | -22.28K Decreased by -23.57% | Apr 30, 25 |
| 5 | Vanguard US Total Market Shares ETF | 85.90K (2.66%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 6 | BlackRock Extended Mkt Composite | 83.46K (2.59%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 7 | Fidelity® Series Total Market Index | 75.06K (2.32%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 8 | Invesco Small Cap Core | 68.88K (2.13%) | 68.88K Increased by +100.00% | Sep 30, 24 |
| 9 | Invesco Main Street Small Cap R6 | 68.88K (2.13%) | 68.88K Increased by +100.00% | Sep 30, 24 |
| 10 | Bridgeway Ultra-Small Company Market | 59.50K (1.84%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 11 | Macquarie Healthcare I | 50.00K (1.55%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 12 | Nomura Healthcare Fund Class I | 50.00K (1.55%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 13 | Vanguard Institutional Extnd Mkt Idx Tr | 41.74K (1.29%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 14 | NT Quality Small Cap Value | 34.62K (1.07%) | 34.62K Increased by +100.00% | Jun 30, 25 |
| 15 | Northern Small Cap Value | 34.62K (1.07%) | 34.62K Increased by +100.00% | Jun 30, 25 |
| 16 | Invesco V.I. Main Street Small Cap I | 32.09K (0.99%) | 32.09K Increased by +100.00% | Sep 30, 24 |
| 17 | Inver-99 SICAV | 25.00K (0.77%) | 0.00 Increased by 0.00% | May 31, 23 |
| 18 | Balaguer 98 de Inversiones SICAV | 25.00K (0.77%) | 0.00 Increased by 0.00% | May 31, 23 |
| 19 | Arctic Aurora LifeScience I USD | 19.50K (0.60%) | 19.50K Increased by +100.00% | Sep 30, 24 |
| 20 | Fidelity Extended Market Index | 19.48K (0.60%) | -67.00 Decreased by -0.34% | Jan 31, 26 |