| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 21.49M (15.92%) | -403.79K Decreased by -1.88% | Mar 31, 25 |
| 2 | Vanguard Group Inc | 15.60M (11.55%) | 8.03K Increased by +0.05% | Mar 31, 25 |
| 3 | State Street Corporation | 7.80M (5.77%) | -456.99K Decreased by -5.86% | Mar 31, 24 |
| 4 | State Street Corp | 7.43M (5.50%) | -1.77M Decreased by -23.76% | Mar 31, 25 |
| 5 | Darwin Global Management, Ltd. | 4.05M (3.00%) | 4.05M Increased by +100.00% | Dec 31, 23 |
| 6 | Geode Capital Management, LLC | 3.28M (2.43%) | 89.06K Increased by +2.71% | Mar 31, 25 |
| 7 | Soleus Capital Management, L.P. | 2.85M (2.11%) | 165.46K Increased by +5.81% | Mar 31, 25 |
| 8 | ClearBridge Advisors, LLC | 2.64M (1.96%) | 809.33K Increased by +30.60% | Mar 31, 25 |
| 9 | Woodline Partners LP | 2.57M (1.90%) | 1.15M Increased by +44.66% | Sep 30, 24 |
| 10 | Pictet Asset Manangement SA | 2.40M (1.77%) | -396.75K Decreased by -16.55% | Mar 31, 25 |
| 11 | Opaleye Management Inc | 2.26M (1.67%) | -20.00K Decreased by -0.88% | Dec 31, 24 |
| 12 | Paradigm Biocapital Advisors LP | 2.17M (1.61%) | -1.45M Decreased by -66.67% | Dec 31, 23 |
| 13 | Marshall Wace Asset Management Ltd | 2.05M (1.52%) | 2.05M Increased by +100.00% | Jun 30, 24 |
| 14 | Morgan Stanley - Brokerage Accounts | 2.05M (1.52%) | -113.89K Decreased by -5.55% | Mar 31, 25 |
| 15 | Goldman Sachs Group Inc | 1.92M (1.42%) | 345.06K Increased by +17.98% | Mar 31, 25 |
| 16 | Sofinnova Ventures | 1.86M (1.38%) | -123.69K Decreased by -6.65% | Jun 30, 24 |
| 17 | Citadel Advisors Llc | 1.86M (1.38%) | 1.48M Increased by +79.34% | Jun 30, 24 |
| 18 | Nuveen Asset Management, LLC | 1.80M (1.33%) | -232.34K Decreased by -12.91% | Dec 31, 24 |
| 19 | FMR Inc | 1.74M (1.29%) | 711.93K Increased by +40.84% | Mar 31, 25 |
| 20 | Deep Track Capital, LP | 1.73M (1.28%) | -1.15M Decreased by -66.38% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | iShares Core S&P Small-Cap ETF | 8.05M (5.96%) | -22.68K Decreased by -0.28% | Jun 30, 25 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 4.50M (3.33%) | 19.64K Increased by +0.44% | May 31, 25 |
| 3 | Vanguard US Total Market Shares ETF | 4.36M (3.23%) | 3.80K Increased by +0.09% | Sep 30, 24 |
| 4 | iShares Russell 2000 ETF | 3.63M (2.68%) | 25.17K Increased by +0.69% | Jun 30, 25 |
| 5 | Vanguard Small Cap Index | 3.53M (2.62%) | 16.61K Increased by +0.47% | May 31, 25 |
| 6 | Vanguard Health Care Inv | 3.07M (2.27%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 7 | SPDR® S&P Biotech ETF | 2.30M (1.70%) | -37.58K Decreased by -1.64% | Jun 30, 25 |
| 8 | Vanguard Institutional Extnd Mkt Idx Tr | 2.08M (1.54%) | 17.16K Increased by +0.83% | May 31, 25 |
| 9 | Vanguard Small Cap Growth Index Inv | 1.95M (1.44%) | -12.91K Decreased by -0.66% | May 31, 25 |
| 10 | Pictet Biotech | 1.79M (1.33%) | 1.79M Increased by +100.00% | Mar 31, 24 |
| 11 | Fidelity Small Cap Index | 1.41M (1.05%) | 16.60K Increased by +1.18% | Apr 30, 25 |
| 12 | Fidelity® Small Cap Index | 1.32M (0.98%) | 35.93K Increased by +2.72% | Oct 31, 23 |
| 13 | iShares Russell 2000 Growth ETF | 1.27M (0.94%) | 101.00 Increased by +0.01% | Jun 30, 25 |
| 14 | iShares S&P Small-Cap 600 Growth ETF | 1.19M (0.88%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 15 | Fidelity® Select Biotechnology | 1.16M (0.86%) | 37.16K Increased by +3.21% | Nov 30, 23 |
| 16 | SPDR® Portfolio S&P 600™ Sm Cap ETF | 1.15M (0.85%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 17 | Vanguard Explorer Inv | 1.06M (0.78%) | 508.58K Increased by +48.13% | Mar 31, 25 |
| 18 | Hood River Small-Cap Growth Instl | 959.04K (0.71%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 19 | Pictet-Biotech P USD | 942.59K (0.70%) | 19.84K Increased by +2.11% | Jun 30, 25 |
| 20 | Pictet-Global Megatrend Sel I USD | 923.81K (0.68%) | -261.18K Decreased by -28.27% | Mar 31, 25 |