| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 21.96M (16.44%) | 10.57M Increased by +48.13% | Sep 30, 24 |
| 2 | Vanguard Group Inc | 15.39M (11.52%) | 1.70M Increased by +11.02% | Sep 30, 24 |
| 3 | State Street Corp | 9.09M (6.81%) | 2.40M Increased by +26.37% | Sep 30, 24 |
| 4 | State Street Corporation | 7.80M (5.84%) | -456.99K Decreased by -5.86% | Mar 31, 24 |
| 5 | Darwin Global Management, Ltd. | 4.05M (3.03%) | 4.05M Increased by +100.00% | Dec 31, 23 |
| 6 | Pictet Asset Manangement SA | 3.58M (2.68%) | 339.10K Increased by +9.47% | Sep 30, 24 |
| 7 | Geode Capital Management, LLC | 3.21M (2.40%) | -1.16K Decreased by -0.04% | Sep 30, 24 |
| 8 | Wellington Management Company LLP | 3.15M (2.36%) | 13.83K Increased by +0.44% | Mar 31, 24 |
| 9 | Woodline Partners LP | 2.57M (1.92%) | 1.15M Increased by +44.66% | Sep 30, 24 |
| 10 | Goldman Sachs Group Inc | 2.56M (1.91%) | 471.72K Increased by +18.45% | Sep 30, 24 |
| 11 | Soleus Capital Management, L.P. | 2.53M (1.90%) | -1.11M Decreased by -43.84% | Sep 30, 24 |
| 12 | Opaleye Management Inc | 2.28M (1.71%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 13 | Paradigm Biocapital Advisors LP | 2.17M (1.63%) | -1.45M Decreased by -66.67% | Dec 31, 23 |
| 14 | Morgan Stanley - Brokerage Accounts | 2.16M (1.62%) | -813.02K Decreased by -37.56% | Sep 30, 24 |
| 15 | Marshall Wace Asset Management Ltd | 2.05M (1.54%) | 2.05M Increased by +100.00% | Jun 30, 24 |
| 16 | Nuveen Asset Management, LLC | 2.03M (1.52%) | 342.67K Increased by +16.87% | Sep 30, 24 |
| 17 | Susquehanna International Group, LLP | 1.95M (1.46%) | 570.90K Increased by +29.30% | Dec 31, 23 |
| 18 | Sofinnova Ventures | 1.86M (1.39%) | -123.69K Decreased by -6.65% | Jun 30, 24 |
| 19 | Citadel Advisors Llc | 1.86M (1.39%) | 1.48M Increased by +79.34% | Jun 30, 24 |
| 20 | Deep Track Capital, LP | 1.73M (1.29%) | -1.15M Decreased by -66.38% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | iShares Core S&P Small-Cap ETF | 8.62M (6.45%) | 3.79K Increased by +0.04% | Dec 31, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 4.37M (3.27%) | 44.83K Increased by +1.03% | Dec 31, 24 |
| 3 | SPDR® S&P Biotech ETF | 3.75M (2.81%) | -66.85K Decreased by -1.78% | Dec 31, 24 |
| 4 | iShares Russell 2000 ETF | 3.74M (2.80%) | -14.38K Decreased by -0.38% | Dec 31, 24 |
| 5 | Vanguard Small Cap Index | 3.57M (2.67%) | 53.60K Increased by +1.50% | Dec 31, 24 |
| 6 | Vanguard Health Care Inv | 3.07M (2.30%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 7 | Vanguard Small Cap Growth Index Inv | 2.02M (1.52%) | 90.71K Increased by +4.48% | Dec 31, 24 |
| 8 | Vanguard Institutional Extnd Mkt Idx Tr | 2.01M (1.51%) | 13.63K Increased by +0.68% | Dec 31, 24 |
| 9 | Pictet Biotech | 1.79M (1.34%) | 1.79M Increased by +100.00% | Mar 31, 24 |
| 10 | Fidelity Small Cap Index | 1.43M (1.07%) | 5.42K Increased by +0.38% | Oct 31, 24 |
| 11 | Pictet-Global Megatrend Sel I USD | 1.37M (1.02%) | 48.77K Increased by +3.57% | Sep 30, 24 |
| 12 | Fidelity® Small Cap Index | 1.32M (0.99%) | 35.93K Increased by +2.72% | Oct 31, 23 |
| 13 | Pictet-Biotech P USD | 1.31M (0.98%) | -115.07K Decreased by -8.79% | Dec 31, 24 |
| 14 | iShares Russell 2000 Growth ETF | 1.28M (0.96%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 15 | iShares S&P Small-Cap 600 Growth ETF | 1.25M (0.93%) | -2.79K Decreased by -0.22% | Dec 31, 24 |
| 16 | SPDR® Portfolio S&P 600™ Sm Cap ETF | 1.22M (0.91%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 17 | Fidelity® Select Biotechnology | 1.16M (0.87%) | 37.16K Increased by +3.21% | Nov 30, 23 |
| 18 | Fidelity Select Biotechnology | 947.72K (0.71%) | 0.00 Increased by 0.00% | Nov 30, 24 |
| 19 | Vanguard Tax-Managed Small Cap Adm | 935.49K (0.70%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 20 | Hood River Small-Cap Growth Instl | 909.77K (0.68%) | 93.82K Increased by +10.31% | Sep 30, 24 |