| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 21.81M (15.54%) | 318.33K Increased by +1.46% | Jun 30, 25 |
| 2 | Vanguard Group Inc | 15.81M (11.26%) | 204.81K Increased by +1.30% | Jun 30, 25 |
| 3 | State Street Corporation | 7.80M (5.55%) | -456.99K Decreased by -5.86% | Mar 31, 24 |
| 4 | State Street Corp | 7.62M (5.43%) | 184.34K Increased by +2.42% | Jun 30, 25 |
| 5 | Darwin Global Management, Ltd. | 4.05M (2.88%) | 4.05M Increased by +100.00% | Dec 31, 23 |
| 6 | Geode Capital Management, LLC | 3.49M (2.49%) | 207.89K Increased by +5.96% | Jun 30, 25 |
| 7 | ClearBridge Advisors, LLC | 3.05M (2.17%) | 408.10K Increased by +13.37% | Jun 30, 25 |
| 8 | Woodline Partners LP | 2.57M (1.83%) | 1.15M Increased by +44.66% | Sep 30, 24 |
| 9 | Opaleye Management Inc | 2.26M (1.61%) | -20.00K Decreased by -0.88% | Dec 31, 24 |
| 10 | Soleus Capital Management, L.P. | 2.24M (1.60%) | -602.77K Decreased by -26.86% | Jun 30, 25 |
| 11 | Paradigm Biocapital Advisors LP | 2.17M (1.55%) | -1.45M Decreased by -66.67% | Dec 31, 23 |
| 12 | Marshall Wace Asset Management Ltd | 2.05M (1.46%) | 2.05M Increased by +100.00% | Jun 30, 24 |
| 13 | Pictet Asset Manangement SA | 1.91M (1.36%) | -489.69K Decreased by -25.67% | Jun 30, 25 |
| 14 | Sofinnova Ventures | 1.86M (1.33%) | -123.69K Decreased by -6.65% | Jun 30, 24 |
| 15 | Nuveen Asset Management, LLC | 1.80M (1.28%) | -232.34K Decreased by -12.91% | Dec 31, 24 |
| 16 | Deep Track Capital, LP | 1.73M (1.23%) | -1.15M Decreased by -66.38% | Sep 30, 24 |
| 17 | Bank of America Corp | 1.70M (1.21%) | -384.52K Decreased by -22.65% | Sep 30, 24 |
| 18 | VOLORIDGE INVESTMENT MANAGEMENT, LLC | 1.61M (1.15%) | 958.95K Increased by +59.47% | Sep 30, 23 |
| 19 | Goldman Sachs Group Inc | 1.57M (1.12%) | -349.51K Decreased by -22.26% | Jun 30, 25 |
| 20 | Hood River Capital Management LLC | 1.57M (1.12%) | 11.02K Increased by +0.70% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | iShares Core S&P Small-Cap ETF | 8.06M (5.74%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 4.52M (3.22%) | -95.21K Decreased by -2.11% | Jul 31, 25 |
| 3 | Vanguard US Total Market Shares ETF | 4.36M (3.11%) | 3.80K Increased by +0.09% | Sep 30, 24 |
| 4 | iShares Russell 2000 ETF | 3.50M (2.49%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 5 | Vanguard Small Cap Index | 3.47M (2.47%) | -23.18K Decreased by -0.67% | Jul 31, 25 |
| 6 | Vanguard Health Care Inv | 3.07M (2.18%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 7 | SPDR® S&P Biotech ETF | 2.30M (1.64%) | 5.12K Increased by +0.22% | Aug 31, 25 |
| 8 | Vanguard Small Cap Growth Index Inv | 1.95M (1.39%) | -4.82K Decreased by -0.25% | Jul 31, 25 |
| 9 | Pictet Biotech | 1.79M (1.28%) | 1.79M Increased by +100.00% | Mar 31, 24 |
| 10 | Vanguard Institutional Extnd Mkt Idx Tr | 1.46M (1.04%) | -633.82K Decreased by -43.48% | Jul 31, 25 |
| 11 | Fidelity Small Cap Index | 1.46M (1.04%) | 41.92K Increased by +2.88% | Jun 30, 25 |
| 12 | Fidelity® Small Cap Index | 1.32M (0.94%) | 35.93K Increased by +2.72% | Oct 31, 23 |
| 13 | iShares Russell 2000 Growth ETF | 1.28M (0.91%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 14 | Vanguard Explorer Inv | 1.26M (0.90%) | 203.15K Increased by +16.12% | Jun 30, 25 |
| 15 | SPDR® Portfolio S&P 600™ Sm Cap ETF | 1.20M (0.85%) | 14.39K Increased by +1.20% | Aug 29, 25 |
| 16 | iShares S&P Small-Cap 600 Growth ETF | 1.17M (0.83%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 17 | Fidelity® Select Biotechnology | 1.16M (0.83%) | 37.16K Increased by +3.21% | Nov 30, 23 |
| 18 | Dynamic Power American Growth | 1.06M (0.75%) | 248.00K Increased by +23.43% | Apr 30, 25 |
| 19 | Eventide Healthcare & Life Sciences I | 954.53K (0.68%) | 235.72K Increased by +24.69% | Jun 30, 25 |
| 20 | Pictet-Biotech P USD | 943.52K (0.67%) | 926.00 Increased by +0.10% | Jul 31, 25 |