| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 22.25M (16.47%) | 404.47K Increased by +1.82% | Mar 31, 26 |
| 2 | Vanguard Group Inc | 15.84M (11.72%) | 319.70K Increased by +2.02% | Dec 31, 25 |
| 3 | State Street Corp | 8.65M (6.40%) | 169.77K Increased by +1.96% | Mar 31, 26 |
| 4 | Vanguard Portfolio Management, LLC | 8.27M (6.12%) | 8.27M Increased by +100.00% | Mar 31, 26 |
| 5 | State Street Corporation | 7.80M (5.77%) | -456.99K Decreased by -5.86% | Mar 31, 24 |
| 6 | Vanguard Capital Management, LLC | 6.60M (4.89%) | 6.60M Increased by +100.00% | Mar 31, 26 |
| 7 | Darwin Global Management, Ltd. | 4.05M (3.00%) | 4.05M Increased by +100.00% | Dec 31, 23 |
| 8 | Soleus Capital Management, L.P. | 4.03M (2.98%) | 890.01K Increased by +22.09% | Mar 31, 26 |
| 9 | Geode Capital Management, LLC | 3.50M (2.59%) | 96.05K Increased by +2.74% | Mar 31, 26 |
| 10 | ClearBridge Advisors, LLC | 3.21M (2.38%) | -237.10K Decreased by -7.38% | Mar 31, 26 |
| 11 | Woodline Partners LP | 2.57M (1.90%) | 1.15M Increased by +44.66% | Sep 30, 24 |
| 12 | The Goldman Sachs Group Inc | 2.29M (1.69%) | 236.56K Increased by +10.34% | Mar 31, 26 |
| 13 | Opaleye Management Inc | 2.26M (1.67%) | -20.00K Decreased by -0.88% | Dec 31, 24 |
| 14 | Paradigm Biocapital Advisors LP | 2.17M (1.61%) | -1.45M Decreased by -66.67% | Dec 31, 23 |
| 15 | Congress Asset Management Company, LLP | 2.17M (1.60%) | 245.67K Increased by +11.33% | Mar 31, 26 |
| 16 | Marshall Wace Asset Management Ltd | 2.05M (1.52%) | 2.05M Increased by +100.00% | Jun 30, 24 |
| 17 | Jane Street Group LLC | 2.04M (1.51%) | 1.07M Increased by +52.49% | Mar 31, 26 |
| 18 | Citadel Advisors Llc | 1.92M (1.42%) | 911.85K Increased by +47.42% | Mar 31, 26 |
| 19 | Sofinnova Ventures | 1.86M (1.38%) | -123.69K Decreased by -6.65% | Jun 30, 24 |
| 20 | Nuveen Asset Management, LLC | 1.80M (1.33%) | -232.34K Decreased by -12.91% | Dec 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | iShares Core S&P Small-Cap ETF | 8.25M (6.11%) | 2.90K Increased by +0.04% | May 29, 26 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 4.83M (3.58%) | 13.31K Increased by +0.28% | Apr 30, 26 |
| 3 | Vanguard US Total Market Shares ETF | 4.36M (3.23%) | 3.80K Increased by +0.09% | Sep 30, 24 |
| 4 | Vanguard Small Cap Index | 3.48M (2.57%) | -6.89K Decreased by -0.20% | Apr 30, 26 |
| 5 | iShares Russell 2000 ETF | 3.47M (2.57%) | 32.08K Increased by +0.92% | May 29, 26 |
| 6 | State Street® SPDR® S&P® Biotech ETF | 3.34M (2.47%) | -20.58K Decreased by -0.62% | May 31, 26 |
| 7 | Vanguard Health Care Inv | 3.07M (2.27%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 8 | SPDR® S&P Biotech ETF | 2.30M (1.70%) | 5.12K Increased by +0.22% | Aug 31, 25 |
| 9 | Vanguard Small Cap Growth Index Inv | 1.95M (1.44%) | -1.80K Decreased by -0.09% | Apr 30, 26 |
| 10 | Pictet Biotech | 1.79M (1.33%) | 1.79M Increased by +100.00% | Mar 31, 24 |
| 11 | Vanguard Institutional Extnd Mkt Idx Tr | 1.53M (1.14%) | 14.18K Increased by +0.92% | Apr 30, 26 |
| 12 | Fidelity Small Cap Index | 1.42M (1.05%) | 2.37K Increased by +0.17% | Mar 31, 26 |
| 13 | Fidelity® Small Cap Index | 1.32M (0.98%) | 35.93K Increased by +2.72% | Oct 31, 23 |
| 14 | ClearBridge SMID Cap Growth | 1.30M (0.96%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 15 | Vanguard Explorer Inv | 1.30M (0.96%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 16 | Congress Small Cap Growth Institutional | 1.30M (0.96%) | 45.00K Increased by +3.46% | Apr 30, 26 |
| 17 | State Street SPDR Port S&P 600 Sm CpETF | 1.25M (0.92%) | 0.00 Increased by 0.00% | May 29, 26 |
| 18 | iShares S&P Small-Cap 600 Growth ETF | 1.20M (0.89%) | -4.30K Decreased by -0.36% | May 29, 26 |
| 19 | SPDR® Portfolio S&P 600™ Sm Cap ETF | 1.20M (0.89%) | 14.39K Increased by +1.20% | Aug 29, 25 |
| 20 | iShares Russell 2000 Growth ETF | 1.18M (0.88%) | -7.71K Decreased by -0.65% | May 29, 26 |