| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 21.90M (16.29%) | -57.44K Decreased by -0.26% | Dec 31, 24 |
| 2 | Vanguard Group Inc | 15.60M (11.60%) | 209.19K Increased by +1.34% | Dec 31, 24 |
| 3 | State Street Corp | 9.20M (6.84%) | 105.75K Increased by +1.15% | Dec 31, 24 |
| 4 | State Street Corporation | 7.80M (5.80%) | -456.99K Decreased by -5.86% | Mar 31, 24 |
| 5 | Darwin Global Management, Ltd. | 4.05M (3.01%) | 4.05M Increased by +100.00% | Dec 31, 23 |
| 6 | Geode Capital Management, LLC | 3.19M (2.37%) | -11.72K Decreased by -0.37% | Dec 31, 24 |
| 7 | Wellington Management Company LLP | 3.15M (2.35%) | 13.83K Increased by +0.44% | Mar 31, 24 |
| 8 | Pictet Asset Manangement SA | 2.79M (2.08%) | -788.65K Decreased by -28.23% | Dec 31, 24 |
| 9 | Soleus Capital Management, L.P. | 2.68M (1.99%) | 146.70K Increased by +5.47% | Dec 31, 24 |
| 10 | Woodline Partners LP | 2.57M (1.91%) | 1.15M Increased by +44.66% | Sep 30, 24 |
| 11 | Opaleye Management Inc | 2.26M (1.68%) | -20.00K Decreased by -0.88% | Dec 31, 24 |
| 12 | Paradigm Biocapital Advisors LP | 2.17M (1.61%) | -1.45M Decreased by -66.67% | Dec 31, 23 |
| 13 | Morgan Stanley - Brokerage Accounts | 2.16M (1.61%) | -34.00 Decreased by -0.00% | Dec 31, 24 |
| 14 | Marshall Wace Asset Management Ltd | 2.05M (1.53%) | 2.05M Increased by +100.00% | Jun 30, 24 |
| 15 | Sofinnova Ventures | 1.86M (1.38%) | -123.69K Decreased by -6.65% | Jun 30, 24 |
| 16 | Citadel Advisors Llc | 1.86M (1.38%) | 1.48M Increased by +79.34% | Jun 30, 24 |
| 17 | ClearBridge Advisors, LLC | 1.84M (1.36%) | 1.84M Increased by +100.00% | Dec 31, 24 |
| 18 | Nuveen Asset Management, LLC | 1.80M (1.34%) | -232.34K Decreased by -12.91% | Dec 31, 24 |
| 19 | Deep Track Capital, LP | 1.73M (1.28%) | -1.15M Decreased by -66.38% | Sep 30, 24 |
| 20 | Bank of America Corp | 1.70M (1.26%) | -384.52K Decreased by -22.65% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | iShares Core S&P Small-Cap ETF | 8.51M (6.33%) | 4.36K Increased by +0.05% | Feb 26, 25 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 4.38M (3.26%) | 10.04K Increased by +0.23% | Jan 31, 25 |
| 3 | iShares Russell 2000 ETF | 3.64M (2.71%) | -71.22K Decreased by -1.96% | Feb 26, 25 |
| 4 | Vanguard Small Cap Index | 3.57M (2.66%) | 6.36K Increased by +0.18% | Jan 31, 25 |
| 5 | SPDR® S&P Biotech ETF | 3.55M (2.64%) | 26.80K Increased by +0.75% | Feb 27, 25 |
| 6 | Vanguard Health Care Inv | 3.07M (2.28%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 7 | Vanguard Small Cap Growth Index Inv | 2.02M (1.50%) | -2.82K Decreased by -0.14% | Jan 31, 25 |
| 8 | Vanguard Institutional Extnd Mkt Idx Tr | 2.01M (1.50%) | 530.00 Increased by +0.03% | Jan 31, 25 |
| 9 | Pictet Biotech | 1.79M (1.33%) | 1.79M Increased by +100.00% | Mar 31, 24 |
| 10 | Fidelity Small Cap Index | 1.42M (1.05%) | -10.12K Decreased by -0.71% | Nov 30, 24 |
| 11 | Pictet-Biotech P USD | 1.33M (0.99%) | 21.17K Increased by +1.59% | Jan 31, 25 |
| 12 | Fidelity® Small Cap Index | 1.32M (0.98%) | 35.93K Increased by +2.72% | Oct 31, 23 |
| 13 | iShares Russell 2000 Growth ETF | 1.25M (0.93%) | -1.47K Decreased by -0.12% | Feb 26, 25 |
| 14 | iShares S&P Small-Cap 600 Growth ETF | 1.23M (0.92%) | 0.00 Increased by 0.00% | Feb 26, 25 |
| 15 | Pictet-Global Megatrend Sel I USD | 1.21M (0.90%) | -161.19K Decreased by -13.34% | Nov 30, 24 |
| 16 | SPDR® Portfolio S&P 600™ Sm Cap ETF | 1.19M (0.88%) | 0.00 Increased by 0.00% | Feb 27, 25 |
| 17 | Fidelity® Select Biotechnology | 1.16M (0.86%) | 37.16K Increased by +3.21% | Nov 30, 23 |
| 18 | Hood River Small-Cap Growth Instl | 959.04K (0.71%) | 49.28K Increased by +5.14% | Dec 31, 24 |
| 19 | Vanguard Tax-Managed Small Cap Adm | 935.49K (0.70%) | 0.00 Increased by 0.00% | Jan 31, 25 |
| 20 | Fidelity Select Biotechnology | 919.22K (0.68%) | -28.50K Decreased by -3.10% | Dec 31, 24 |