| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Bvf Inc | 4.89M (12.01%) | 1.90M Increased by +38.86% | Mar 31, 25 |
| 2 | BlackRock Inc | 4.88M (11.98%) | -82.87K Decreased by -1.70% | Mar 31, 25 |
| 3 | Adage Capital Partners Gp LLC | 3.50M (8.60%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 4 | Baker Bros Advisors LP | 2.78M (6.84%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 5 | Vanguard Group Inc | 2.36M (5.79%) | -25.79K Decreased by -1.09% | Mar 31, 25 |
| 6 | Propel Bio Management LLC | 2.09M (5.13%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 7 | Checkpoint Capital LP | 2.02M (4.96%) | 261.66K Increased by +12.97% | Mar 31, 25 |
| 8 | Alphabet Inc | 1.08M (2.65%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 9 | Simplify Asset Management Inc. | 1.05M (2.57%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 10 | Geode Capital Management, LLC | 1.02M (2.49%) | 51.83K Increased by +5.11% | Mar 31, 25 |
| 11 | Great Point Partners LLC | 940.83K (2.31%) | 940.83K Increased by +100.00% | Jun 30, 24 |
| 12 | Aberdeen Group PLC | 891.45K (2.19%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 13 | StemPoint Capital LP | 860.95K (2.11%) | 15.88K Increased by +1.84% | Sep 30, 24 |
| 14 | State Street Corp | 817.25K (2.01%) | 16.30K Increased by +1.99% | Mar 31, 25 |
| 15 | LMR Partners LLP | 665.53K (1.63%) | 665.53K Increased by +100.00% | Jun 30, 24 |
| 16 | EcoR1 Capital, LLC | 662.83K (1.63%) | -4.34M Decreased by -654.34% | Mar 31, 25 |
| 17 | DC Funds, LP | 630.00K (1.55%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 18 | TANG CAPITAL MANAGEMENT LLC | 600.00K (1.47%) | 482.15K Increased by +80.36% | Mar 31, 25 |
| 19 | Morgan Stanley - Brokerage Accounts | 592.97K (1.46%) | 180.11K Increased by +30.37% | Mar 31, 25 |
| 20 | Amvescap Plc. | 499.87K (1.23%) | 11.46K Increased by +2.29% | Jun 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 1.37M (3.37%) | 0.00 Increased by 0.00% | May 31, 25 |
| 2 | Simplify Propel Opportunities ETF | 1.05M (2.57%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 3 | BlackRock Health Sciences Term Trust | 1.05M (2.57%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 4 | Vanguard Institutional Extnd Mkt Idx Tr | 706.08K (1.73%) | 0.00 Increased by 0.00% | May 31, 25 |
| 5 | BlackRock Health Sciences Opps Inv A | 650.52K (1.60%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 6 | abrdn Healthcare Investors | 498.01K (1.22%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 7 | abrdn Life Sciences Investors | 393.44K (0.97%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 8 | Fidelity Small Cap Index | 392.73K (0.96%) | 13.42K Increased by +3.42% | Apr 30, 25 |
| 9 | Fidelity Extended Market Index | 284.10K (0.70%) | -1.27K Decreased by -0.45% | May 31, 25 |
| 10 | iShares Biotechnology ETF | 274.36K (0.67%) | -990.00 Decreased by -0.36% | Jun 30, 25 |
| 11 | State St Russell Sm/Mid Cp® Indx NL Cl C | 217.61K (0.53%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 12 | State St Russell Sm/Mid Cp® Indx SL Cl I | 217.61K (0.53%) | 0.00 Increased by 0.00% | May 31, 25 |
| 13 | iShares Russell 2000 Growth ETF | 213.91K (0.53%) | 0.00 Increased by 0.00% | May 31, 25 |
| 14 | Fidelity® Extended Market Index | 209.06K (0.51%) | 5.06K Increased by +2.42% | Nov 30, 23 |
| 15 | BIT Biotech Opportunities S | 204.76K (0.50%) | 74.21K Increased by +36.24% | Nov 30, 24 |
| 16 | Vanguard Russell 2000 ETF | 191.93K (0.47%) | 1.75K Increased by +0.91% | May 31, 25 |
| 17 | State St Russell Sm Cap® Indx SL Cl I | 164.00K (0.40%) | 0.00 Increased by 0.00% | May 31, 25 |
| 18 | Tocqueville Asset Mgt Multi Cap Equity | 149.70K (0.37%) | 34.00K Increased by +22.71% | Dec 31, 24 |
| 19 | A4Investments SICAV SIF ACCI IlanaA2EURH | 138.83K (0.34%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 20 | iShares Russell 2000 Value ETF | 120.24K (0.30%) | 0.00 Increased by 0.00% | May 31, 25 |