| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Lynx1 Capital Management, LP | 8.02M (14.48%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 2 | Bvf Inc | 5.23M (9.44%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 3 | Adage Capital Partners Gp LLC | 3.50M (6.32%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 4 | Baker Bros Advisors LP | 2.78M (5.03%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 5 | Vanguard Group Inc | 2.48M (4.47%) | 157.82K Increased by +6.37% | Dec 31, 25 |
| 6 | Propel Bio Management LLC | 2.09M (3.77%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 7 | Checkpoint Capital LP | 2.02M (3.64%) | 261.66K Increased by +12.97% | Mar 31, 25 |
| 8 | BlackRock Inc | 1.85M (3.34%) | -534.07K Decreased by -28.89% | Dec 31, 25 |
| 9 | Renaissance Technologies Corp | 1.36M (2.46%) | 223.71K Increased by +16.39% | Mar 31, 26 |
| 10 | Deer Management Co. LLC | 1.25M (2.25%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 11 | Alphabet Inc | 1.08M (1.94%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 12 | Simplify Asset Management Inc. | 1.05M (1.89%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 13 | Great Point Partners LLC | 940.83K (1.70%) | 940.83K Increased by +100.00% | Jun 30, 24 |
| 14 | Aberdeen Group PLC | 918.02K (1.66%) | -867.22K Decreased by -94.47% | Mar 31, 26 |
| 15 | StemPoint Capital LP | 860.95K (1.55%) | 15.88K Increased by +1.84% | Sep 30, 24 |
| 16 | LMR Partners LLP | 665.53K (1.20%) | 665.53K Increased by +100.00% | Jun 30, 24 |
| 17 | EcoR1 Capital, LLC | 662.83K (1.20%) | -4.34M Decreased by -654.34% | Mar 31, 25 |
| 18 | Two Sigma Investments LLC | 651.18K (1.18%) | 231.78K Increased by +35.59% | Dec 31, 25 |
| 19 | DC Funds, LP | 630.00K (1.14%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 20 | TANG CAPITAL MANAGEMENT LLC | 600.00K (1.08%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 1.50M (2.71%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 2 | Simplify Propel Opportunities ETF | 1.05M (1.89%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 3 | abrdn Life Sciences Investors | 836.78K (1.51%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 4 | Vanguard Institutional Extnd Mkt Idx Tr | 577.59K (1.04%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 5 | BlackRock Health Sciences Opps Inv A | 556.65K (1.00%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 6 | BlackRock Health Sciences Term Trust | 407.01K (0.73%) | -202.79K Decreased by -49.82% | Dec 31, 25 |
| 7 | Fidelity Small Cap Index | 392.73K (0.71%) | 0.00 Increased by 0.00% | May 31, 25 |
| 8 | Fidelity Extended Market Index | 319.69K (0.58%) | 48.25K Increased by +15.09% | Mar 31, 26 |
| 9 | iShares Biotechnology ETF | 262.48K (0.47%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 10 | State St Russell Sm/Mid Cp® Indx NL Cl C | 217.61K (0.39%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 11 | State St Russell Sm/Mid Cp® Indx SL Cl I | 217.61K (0.39%) | 0.00 Increased by 0.00% | May 31, 25 |
| 12 | iShares Russell 2000 Growth ETF | 213.91K (0.39%) | 0.00 Increased by 0.00% | May 31, 25 |
| 13 | Fidelity® Extended Market Index | 209.06K (0.38%) | 5.06K Increased by +2.42% | Nov 30, 23 |
| 14 | BIT Biotech Opportunities S | 204.76K (0.37%) | 74.21K Increased by +36.24% | Nov 30, 24 |
| 15 | A4Investments SICAV SIF ACCI IlanaA2EURH | 200.00K (0.36%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 16 | Vanguard Russell 2000 ETF | 191.93K (0.35%) | 1.75K Increased by +0.91% | May 31, 25 |
| 17 | State St Russell Sm Cap® Indx SL Cl I | 164.00K (0.30%) | 0.00 Increased by 0.00% | May 31, 25 |
| 18 | Tocqueville Asset Mgt Multi Cap Equity | 149.70K (0.27%) | 34.00K Increased by +22.71% | Dec 31, 24 |
| 19 | iShares Russell 2000 Value ETF | 120.24K (0.22%) | 0.00 Increased by 0.00% | May 31, 25 |
| 20 | iShares Micro-Cap ETF | 116.80K (0.21%) | 0.00 Increased by 0.00% | Apr 30, 26 |