| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 3.54M (12.12%) | -216.66K Decreased by -6.12% | Dec 31, 24 |
| 2 | RTW INVESTMENTS, LLC | 3.24M (11.09%) | -175.94K Decreased by -5.44% | Dec 31, 24 |
| 3 | Paradigm Biocapital Advisors LP | 2.53M (8.67%) | 91.45K Increased by +3.61% | Dec 31, 24 |
| 4 | Jennison Associates LLC | 2.50M (8.56%) | 321.55K Increased by +12.86% | Dec 31, 24 |
| 5 | TANG CAPITAL MANAGEMENT LLC | 2.25M (7.72%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 6 | COWEN AND COMPANY, LLC | 2.20M (7.53%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 7 | Vanguard Group Inc | 2.12M (7.24%) | 17.84K Increased by +0.84% | Dec 31, 24 |
| 8 | Morgan Stanley - Brokerage Accounts | 1.97M (6.74%) | -239.52K Decreased by -12.16% | Dec 31, 24 |
| 9 | The Toronto-Dominion Bank | 1.91M (6.54%) | 1.91M Increased by +100.00% | Dec 31, 24 |
| 10 | Perceptive Advisors LLC | 1.30M (4.44%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 11 | Lord, Abbett & Co LLC | 1.28M (4.38%) | 685.11K Increased by +53.52% | Dec 31, 24 |
| 12 | Assenagon Asset Management SA | 1.15M (3.93%) | 5.57K Increased by +0.49% | Dec 31, 24 |
| 13 | Amvescap Plc. | 932.12K (3.19%) | 250.02K Increased by +26.82% | Dec 31, 24 |
| 14 | State Street Corp | 916.86K (3.14%) | 17.48K Increased by +1.91% | Dec 31, 24 |
| 15 | HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | 898.00K (3.08%) | 824.00K Increased by +91.76% | Mar 31, 24 |
| 16 | ExodusPoint Capital Management, LP | 883.04K (3.02%) | 212.58K Increased by +24.07% | Sep 30, 24 |
| 17 | JPMorgan Chase & Co | 880.33K (3.02%) | 840.11K Increased by +95.43% | Sep 30, 24 |
| 18 | Geode Capital Management, LLC | 838.80K (2.87%) | 3.01K Increased by +0.36% | Dec 31, 24 |
| 19 | Macquarie Group Ltd | 815.91K (2.79%) | 221.03K Increased by +27.09% | Dec 31, 24 |
| 20 | Deerfield Management Co | 754.04K (2.58%) | 754.04K Increased by +100.00% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 1.14M (3.91%) | 1.05K Increased by +0.09% | Feb 28, 25 |
| 2 | iShares Russell 2000 ETF | 947.34K (3.24%) | -11.17K Decreased by -1.18% | Feb 28, 25 |
| 3 | Jennison SMid Cap Core Equity | 664.86K (2.28%) | 185.97K Increased by +27.97% | Dec 31, 24 |
| 4 | PGIM Jennison Small Company A | 664.86K (2.28%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 5 | Lord Abbett Developing Growth A | 569.17K (1.95%) | 0.00 Increased by 0.00% | Jan 31, 25 |
| 6 | Vanguard Institutional Extnd Mkt Idx Tr | 527.80K (1.81%) | 3.41K Increased by +0.65% | Feb 28, 25 |
| 7 | Invesco Small Cap Value A | 491.19K (1.68%) | 0.00 Increased by 0.00% | Jan 31, 25 |
| 8 | MEDICAL BioHealth EUR Acc | 488.32K (1.67%) | 66.98K Increased by +13.72% | Nov 30, 24 |
| 9 | Artisan International Small-Mid Investor | 457.19K (1.57%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 10 | Artisan Non-U.S. Small-Mid Growth Comp | 457.19K (1.57%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 11 | Macquarie Small Cap Growth C | 452.00K (1.55%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 12 | AZ InvestEd Ivy Small Cap Growth E | 389.81K (1.34%) | -62.19K Decreased by -15.95% | Jan 31, 25 |
| 13 | Jennison Health Sciences Equity | 382.76K (1.31%) | -75.18K Decreased by -19.64% | Dec 31, 24 |
| 14 | PGIM Jennison Health Sciences Z | 382.76K (1.31%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 15 | Fidelity Small Cap Index | 369.47K (1.27%) | -3.22K Decreased by -0.87% | Dec 31, 24 |
| 16 | iShares Russell 2000 Growth ETF | 328.25K (1.12%) | -388.00 Decreased by -0.12% | Feb 28, 25 |
| 17 | Delaware Ivy Small Cap Growth C | 303.11K (1.04%) | 41.62K Increased by +13.73% | Sep 30, 24 |
| 18 | APO Medical Opportunities R | 289.25K (0.99%) | 82.44K Increased by +28.50% | Jan 31, 25 |
| 19 | iShares Russell 2000 Value ETF | 270.00K (0.92%) | 0.00 Increased by 0.00% | Apr 30, 24 |
| 20 | CREF Stock R1 | 254.34K (0.87%) | 0.00 Increased by 0.00% | Jun 30, 24 |