| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 11.78M (14.54%) | 142.21K Increased by +1.21% | Mar 31, 26 |
| 2 | BlackRock Inc | 5.52M (6.81%) | -880.00 Decreased by -0.02% | Mar 31, 26 |
| 3 | RTW INVESTMENTS, LLC | 4.17M (5.15%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 4 | Vanguard Group Inc | 4.04M (4.98%) | 984.34K Increased by +24.39% | Dec 31, 25 |
| 5 | Fairmount Funds Management LLC | 4.02M (4.96%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 6 | Perceptive Advisors LLC | 3.78M (4.67%) | 714.00K Increased by +18.87% | Mar 31, 26 |
| 7 | VR Adviser, LLC | 3.69M (4.55%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 8 | Vanguard Capital Management, LLC | 3.06M (3.77%) | 3.06M Increased by +100.00% | Mar 31, 26 |
| 9 | Driehaus Capital Management LLC | 2.79M (3.44%) | -91.64K Decreased by -3.28% | Mar 31, 26 |
| 10 | State Street Corp | 2.61M (3.22%) | 344.19K Increased by +13.20% | Mar 31, 26 |
| 11 | Paradigm Biocapital Advisors LP | 1.96M (2.41%) | 490.00K Increased by +25.03% | Mar 31, 26 |
| 12 | COMMODORE CAPITAL LP | 1.91M (2.36%) | -475.87K Decreased by -24.88% | Mar 31, 26 |
| 13 | TCG Crossover Management, LLC | 1.90M (2.34%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 14 | TANG CAPITAL MANAGEMENT LLC | 1.89M (2.33%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 15 | Wellington Management Company LLP | 1.82M (2.25%) | 275.53K Increased by +15.10% | Mar 31, 26 |
| 16 | Capital Research & Mgmt Co - Division 3 | 1.75M (2.15%) | -1.75M Decreased by -100.02% | Mar 31, 26 |
| 17 | Geode Capital Management, LLC | 1.72M (2.12%) | 61.77K Increased by +3.59% | Mar 31, 26 |
| 18 | HHG PLC | 1.66M (2.04%) | -172.84K Decreased by -10.44% | Mar 31, 26 |
| 19 | RA Capital Management, LLC | 1.62M (2.00%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 20 | T. Rowe Price Associates, Inc. | 1.60M (1.97%) | -3.15K Decreased by -0.20% | Mar 31, 26 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Fidelity Growth Compy Commingled Pl S | 3.39M (4.18%) | 208.08K Increased by +6.14% | Apr 30, 26 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 2.44M (3.02%) | 224.90K Increased by +9.20% | Apr 30, 26 |
| 3 | Fidelity Growth Company Fund | 2.43M (3.00%) | 166.08K Increased by +6.82% | Apr 30, 26 |
| 4 | American Funds SMALLCAP World A | 2.41M (2.98%) | -1.28M Decreased by -53.05% | Mar 31, 26 |
| 5 | iShares Russell 2000 ETF | 1.79M (2.20%) | 16.48K Increased by +0.92% | May 29, 26 |
| 6 | State Street® SPDR® S&P® Biotech ETF | 1.18M (1.46%) | -7.29K Decreased by -0.62% | May 31, 26 |
| 7 | Polar Capital Biotech S Inc | 986.26K (1.22%) | 236.43K Increased by +23.97% | Apr 30, 26 |
| 8 | T. Rowe Price Health Sciences | 851.95K (1.05%) | -45.10K Decreased by -5.29% | Apr 30, 26 |
| 9 | Fidelity Advisor Biotechnology I | 851.77K (1.05%) | 4.38K Increased by +0.51% | Apr 30, 26 |
| 10 | Vanguard Institutional Extnd Mkt Idx Tr | 845.61K (1.04%) | 81.91K Increased by +9.69% | Apr 30, 26 |
| 11 | Fidelity Select Health Care | 800.00K (0.99%) | -140.00K Decreased by -17.50% | Apr 30, 26 |
| 12 | Fidelity Small Cap Growth | 766.82K (0.95%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 13 | Fidelity Growth Company K6 | 711.94K (0.88%) | 44.16K Increased by +6.20% | Apr 30, 26 |
| 14 | Wellington CIF II Small Cap 2000 | 693.01K (0.86%) | 693.01K Increased by +100.00% | Sep 30, 25 |
| 15 | Fidelity Small Cap Index | 675.52K (0.83%) | 1.12K Increased by +0.17% | Mar 31, 26 |
| 16 | Fidelity Series Growth Company | 635.81K (0.78%) | 44.00K Increased by +6.92% | Apr 30, 26 |
| 17 | Pictet-Biotech P USD | 582.20K (0.72%) | 582.20K Increased by +100.00% | Jan 31, 26 |
| 18 | iShares Biotechnology ETF | 567.86K (0.70%) | 100.71K Increased by +17.73% | May 29, 26 |
| 19 | Franklin Biotechnology Discv A(acc)USD | 554.27K (0.68%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 20 | Fidelity Advisor Health Care I | 480.00K (0.59%) | 0.00 Increased by 0.00% | Mar 31, 26 |