| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | NEA Management Company, LLC | 24.47M (20.73%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 2 | Bain Capital Life Sciences Investors, LLC | 17.60M (14.91%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 3 | TCG Crossover Management, LLC | 12.36M (10.47%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 4 | Vestal Point Capital LP | 11.02M (9.33%) | 15.00K Increased by +0.14% | Jun 30, 25 |
| 5 | BlackRock Inc | 9.78M (8.28%) | -170.74K Decreased by -1.75% | Jun 30, 25 |
| 6 | VR Adviser, LLC | 8.88M (7.53%) | 5.63M Increased by +63.33% | Jun 30, 25 |
| 7 | Vanguard Group Inc | 8.45M (7.16%) | 334.73K Increased by +3.96% | Jun 30, 25 |
| 8 | Nantahala Capital Management, LLC | 8.33M (7.05%) | 250.00K Increased by +3.00% | Jun 30, 25 |
| 9 | Deerfield Management Co | 7.96M (6.75%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 10 | Farallon Capital Management, L.L.C. | 6.83M (5.79%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 11 | Jennison Associates LLC | 6.73M (5.70%) | 1.00M Increased by +14.87% | Sep 30, 24 |
| 12 | ADAR1 Capital Management LLC | 3.60M (3.05%) | 2.24M Increased by +62.22% | Jun 30, 25 |
| 13 | Emerald Advisers, LLC | 3.53M (2.99%) | 444.15K Increased by +12.57% | Jun 30, 25 |
| 14 | Wellington Management Company LLP | 3.35M (2.84%) | -812.38K Decreased by -24.25% | Jun 30, 25 |
| 15 | Caxton Corp | 3.31M (2.81%) | -1.67M Decreased by -50.31% | Sep 30, 23 |
| 16 | Geode Capital Management, LLC | 2.97M (2.52%) | 147.95K Increased by +4.98% | Jun 30, 25 |
| 17 | ExodusPoint Capital Management, LP | 2.79M (2.37%) | -25.84K Decreased by -0.92% | Sep 30, 24 |
| 18 | Woodline Partners LP | 2.69M (2.28%) | 381.74K Increased by +14.21% | Dec 31, 24 |
| 19 | Rosalind Advisors, Inc. | 2.65M (2.25%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 20 | Sofinnova Ventures | 2.46M (2.08%) | -3.02M Decreased by -123.07% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 5.10M (4.32%) | -113.17K Decreased by -2.22% | Jul 31, 25 |
| 2 | Vanguard US Total Market Shares ETF | 4.93M (4.18%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 3 | Jennison Health Sciences Equity | 3.78M (3.20%) | 463.66K Increased by +12.28% | Sep 30, 24 |
| 4 | PGIM Jennison Health Sciences Z | 3.78M (3.20%) | 0.00 Increased by 0.00% | Oct 31, 24 |
| 5 | iShares Russell 2000 ETF | 3.03M (2.57%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 6 | SPDR® S&P Biotech ETF | 1.56M (1.32%) | -9.50K Decreased by -0.61% | Feb 28, 25 |
| 7 | Fidelity Small Cap Index | 1.27M (1.08%) | 37.61K Increased by +2.96% | Jun 30, 25 |
| 8 | Vanguard Institutional Extnd Mkt Idx Tr | 1.26M (1.07%) | -574.05K Decreased by -45.63% | Jul 31, 25 |
| 9 | iShares Russell 2000 Growth ETF | 1.14M (0.97%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 10 | UTM IM GBP AXA Framlington Biotech | 1.01M (0.85%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 11 | Emerald Growth A | 1.00M (0.85%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 12 | Fidelity Advisor Biotechnology I | 986.50K (0.84%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 13 | Principal SmallCap Growth I Instl | 925.48K (0.78%) | 102.35K Increased by +11.06% | Jul 31, 25 |
| 14 | Fidelity® Small Cap Index | 874.11K (0.74%) | 26.44K Increased by +3.03% | Oct 31, 23 |
| 15 | iShares Russell 2000 Value ETF | 790.67K (0.67%) | 0.00 Increased by 0.00% | Apr 30, 24 |
| 16 | State St Russell Sm/Mid Cp® Indx NL Cl C | 690.85K (0.59%) | 3.20K Increased by +0.46% | Apr 30, 25 |
| 17 | State St Russell Sm/Mid Cp® Indx SL Cl I | 690.85K (0.59%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 18 | Fidelity Extended Market Index | 630.49K (0.53%) | -5.19K Decreased by -0.82% | Jul 31, 25 |
| 19 | DWS ESG Biotech LC | 620.03K (0.53%) | -1.00 Decreased by -0.00% | Jul 31, 25 |
| 20 | Vanguard Russell 2000 ETF | 603.28K (0.51%) | -23.30K Decreased by -3.86% | Jul 31, 25 |