| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | NEA Management Company, LLC | 24.47M (18.81%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 2 | Bain Capital Life Sciences Investors, LLC | 17.60M (13.53%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 3 | VR Adviser, LLC | 13.74M (10.56%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 4 | Deerfield Management Co | 13.57M (10.43%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 5 | TCG Crossover Management, LLC | 12.36M (9.50%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 6 | BlackRock Inc | 11.29M (8.68%) | 193.90K Increased by +1.72% | Mar 31, 26 |
| 7 | Vanguard Group Inc | 10.04M (7.72%) | 1.73M Increased by +17.21% | Dec 31, 25 |
| 8 | Frazier Life Sciences Management, L.P. | 9.72M (7.47%) | -141.45K Decreased by -1.46% | Mar 31, 26 |
| 9 | Polar Capital Holdings PLC | 9.54M (7.33%) | 1.24M Increased by +12.95% | Mar 31, 26 |
| 10 | Vanguard Capital Management, LLC | 7.78M (5.98%) | 7.78M Increased by +100.00% | Mar 31, 26 |
| 11 | Nantahala Capital Management, LLC | 7.34M (5.64%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 12 | Farallon Capital Management, L.L.C. | 6.83M (5.25%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 13 | Jennison Associates LLC | 6.73M (5.17%) | 1.00M Increased by +14.87% | Sep 30, 24 |
| 14 | State Street Corp | 6.71M (5.16%) | 2.37M Increased by +35.40% | Mar 31, 26 |
| 15 | RTW INVESTMENTS, LLC | 5.95M (4.57%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 16 | Marshall Wace Asset Management Ltd | 4.51M (3.47%) | -45.57K Decreased by -1.01% | Mar 31, 26 |
| 17 | Woodline Partners LP | 4.25M (3.26%) | 479.00 Increased by +0.01% | Mar 31, 26 |
| 18 | ADAR1 Capital Management LLC | 3.60M (2.77%) | 2.24M Increased by +62.22% | Jun 30, 25 |
| 19 | Geode Capital Management, LLC | 3.59M (2.76%) | 176.71K Increased by +4.92% | Mar 31, 26 |
| 20 | Spruce Street Capital LP | 3.38M (2.60%) | 972.08K Increased by +28.73% | Mar 31, 26 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Polar Capital Healthcare Opports Inc | 8.19M (6.30%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 6.07M (4.67%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 3 | Vanguard US Total Market Shares ETF | 4.93M (3.79%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 4 | State Street® SPDR® S&P® Biotech ETF | 3.89M (2.99%) | -24.18K Decreased by -0.62% | May 31, 26 |
| 5 | Jennison Health Sciences Equity | 3.78M (2.90%) | 463.66K Increased by +12.28% | Sep 30, 24 |
| 6 | PGIM Jennison Health Sciences Z | 3.78M (2.90%) | 0.00 Increased by 0.00% | Oct 31, 24 |
| 7 | iShares Russell 2000 ETF | 3.52M (2.70%) | 32.50K Increased by +0.92% | May 29, 26 |
| 8 | SPDR® S&P Biotech ETF | 1.56M (1.20%) | -9.50K Decreased by -0.61% | Feb 28, 25 |
| 9 | Vanguard Institutional Extnd Mkt Idx Tr | 1.53M (1.18%) | 22.57K Increased by +1.47% | Apr 30, 26 |
| 10 | Fidelity Small Cap Index | 1.44M (1.11%) | 51.50K Increased by +3.58% | Mar 31, 26 |
| 11 | Polar Capital Glb Healthcare Ord | 1.35M (1.04%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 12 | iShares Russell 2000 Growth ETF | 1.19M (0.91%) | -7.71K Decreased by -0.65% | May 29, 26 |
| 13 | UTM IM GBP AXA Framlington Biotech | 1.01M (0.77%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 14 | Fidelity Advisor Biotechnology I | 986.50K (0.76%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 15 | Principal SmallCap Growth I Instl | 927.79K (0.71%) | -1.34K Decreased by -0.14% | Apr 30, 26 |
| 16 | Russell 2000 Equity Index Fund B | 894.39K (0.69%) | 195.85K Increased by +21.90% | Dec 31, 25 |
| 17 | Fidelity® Small Cap Index | 874.11K (0.67%) | 26.44K Increased by +3.03% | Oct 31, 23 |
| 18 | State St Russell Sm/Mid Cp® Indx SL Cl I | 855.85K (0.66%) | 0.00 Increased by 0.00% | May 31, 26 |
| 19 | Emerald Growth A | 798.88K (0.61%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 20 | iShares Russell 2000 Value ETF | 790.67K (0.61%) | 0.00 Increased by 0.00% | Apr 30, 24 |