| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | NEA Management Company, LLC | 24.47M (24.03%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | Bain Capital Life Sciences Investors, LLC | 14.57M (14.30%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 3 | TCG Crossover Management, LLC | 12.36M (12.14%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 4 | Vestal Point Capital LP | 10.78M (10.58%) | 2.69M Increased by +24.92% | Dec 31, 24 |
| 5 | BlackRock Inc | 9.59M (9.41%) | 189.01K Increased by +1.97% | Dec 31, 24 |
| 6 | Vanguard Group Inc | 8.31M (8.16%) | 365.96K Increased by +4.40% | Dec 31, 24 |
| 7 | Deerfield Management Co | 7.96M (7.82%) | 1.50M Increased by +18.81% | Dec 31, 24 |
| 8 | Nantahala Capital Management, LLC | 7.53M (7.39%) | 2.34M Increased by +31.15% | Dec 31, 24 |
| 9 | VR Adviser, LLC | 7.18M (7.05%) | 833.33K Increased by +11.60% | Sep 30, 23 |
| 10 | Farallon Capital Management, L.L.C. | 6.83M (6.71%) | 2.27M Increased by +33.28% | Dec 31, 24 |
| 11 | Jennison Associates LLC | 6.73M (6.61%) | 1.00M Increased by +14.87% | Sep 30, 24 |
| 12 | Wellington Management Company LLP | 5.48M (5.38%) | -3.14M Decreased by -57.32% | Dec 31, 24 |
| 13 | Sofinnova Ventures | 5.47M (5.37%) | -191.25K Decreased by -3.50% | Dec 31, 24 |
| 14 | State Street Corp | 4.17M (4.10%) | 35.80K Increased by +0.86% | Dec 31, 24 |
| 15 | Caxton Corp | 3.31M (3.25%) | -1.67M Decreased by -50.31% | Sep 30, 23 |
| 16 | ExodusPoint Capital Management, LP | 2.79M (2.74%) | -25.84K Decreased by -0.92% | Sep 30, 24 |
| 17 | Geode Capital Management, LLC | 2.78M (2.73%) | 57.19K Increased by +2.05% | Dec 31, 24 |
| 18 | Woodline Partners LP | 2.69M (2.64%) | 381.74K Increased by +14.21% | Dec 31, 24 |
| 19 | Rosalind Advisors, Inc. | 2.65M (2.61%) | 2.65M Increased by +100.00% | Dec 31, 24 |
| 20 | Emerald Advisers, LLC | 2.33M (2.29%) | 2.33M Increased by +100.00% | Dec 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 5.12M (5.02%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 2 | Jennison Health Sciences Equity | 3.78M (3.71%) | 463.66K Increased by +12.28% | Sep 30, 24 |
| 3 | PGIM Jennison Health Sciences Z | 3.78M (3.71%) | 0.00 Increased by 0.00% | Oct 31, 24 |
| 4 | iShares Russell 2000 ETF | 3.20M (3.14%) | -27.72K Decreased by -0.87% | Mar 31, 25 |
| 5 | Vanguard Institutional Extnd Mkt Idx Tr | 1.97M (1.93%) | 4.34K Increased by +0.22% | Feb 28, 25 |
| 6 | SPDR® S&P Biotech ETF | 1.56M (1.53%) | -9.50K Decreased by -0.61% | Feb 28, 25 |
| 7 | Fidelity Small Cap Index | 1.15M (1.13%) | -21.53K Decreased by -1.87% | Jan 31, 25 |
| 8 | Emerald Growth A | 1.08M (1.06%) | 334.15K Increased by +30.83% | Feb 28, 25 |
| 9 | UTM IM GBP AXA Framlington Biotech | 1.01M (0.99%) | 0.00 Increased by 0.00% | Jan 31, 25 |
| 10 | Fidelity Advisor Biotechnology I | 986.50K (0.97%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 11 | Fidelity® Small Cap Index | 874.11K (0.86%) | 26.44K Increased by +3.03% | Oct 31, 23 |
| 12 | iShares Russell 2000 Growth ETF | 844.51K (0.83%) | -4.02K Decreased by -0.48% | Mar 31, 25 |
| 13 | iShares Russell 2000 Value ETF | 790.67K (0.78%) | 0.00 Increased by 0.00% | Apr 30, 24 |
| 14 | State St Russell Sm/Mid Cp® Indx NL Cl C | 748.64K (0.74%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 15 | Principal SmallCap Growth I Instl | 717.68K (0.70%) | 162.75K Increased by +22.68% | Feb 28, 25 |
| 16 | Fidelity Extended Market Index | 633.40K (0.62%) | -4.04K Decreased by -0.64% | Feb 28, 25 |
| 17 | DWS ESG Biotech LC | 620.02K (0.61%) | 5.00 Increased by +0.00% | Feb 28, 25 |
| 18 | Hartford Healthcare Y | 580.81K (0.57%) | -35.30K Decreased by -6.08% | Feb 28, 25 |
| 19 | MEDICAL BioHealth EUR Acc | 575.46K (0.56%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 20 | iShares Biotechnology ETF | 558.82K (0.55%) | -6.22K Decreased by -1.11% | Mar 31, 25 |