| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Suvretta Capital Management, LLC | 6.49M (9.67%) | -974.17K Decreased by -15.01% | Jun 30, 25 |
| 2 | BlackRock Inc | 6.20M (9.24%) | -1.39M Decreased by -22.38% | Mar 31, 25 |
| 3 | Kynam Capital Management, LP | 5.09M (7.58%) | -353.35K Decreased by -6.94% | Jun 30, 25 |
| 4 | RA Capital Management, LLC | 4.43M (6.61%) | 4.43M Increased by +100.00% | Mar 31, 25 |
| 5 | Vanguard Group Inc | 4.12M (6.13%) | -279.99K Decreased by -6.80% | Jun 30, 25 |
| 6 | Bvf Inc | 3.35M (4.99%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 7 | Rubric Capital Management LP | 3.34M (4.98%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 8 | Acadian Asset Management LLC | 3.13M (4.67%) | 3.04M Increased by +96.83% | Mar 31, 25 |
| 9 | Velan Capital Investment Management LP | 3.06M (4.56%) | 2.03M Increased by +66.34% | Jun 30, 25 |
| 10 | Franklin Resources Inc | 2.76M (4.12%) | -71.72K Decreased by -2.60% | Dec 31, 23 |
| 11 | Merck & Co Inc | 2.72M (4.06%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 12 | Vestal Point Capital LP | 2.60M (3.87%) | 30.00K Increased by +1.15% | Mar 31, 25 |
| 13 | TANG CAPITAL MANAGEMENT LLC | 2.56M (3.82%) | 2.36M Increased by +92.19% | Jun 30, 25 |
| 14 | Verition Fund Managegment, LLC | 2.50M (3.73%) | 555.02K Increased by +22.19% | Sep 30, 23 |
| 15 | Eversept Partners, LLC | 2.29M (3.42%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 16 | Point72 Asset Management, L.P. | 2.20M (3.27%) | -799.91K Decreased by -36.40% | Dec 31, 24 |
| 17 | Samsara BioCapital, LLC | 2.20M (3.27%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 18 | MPM Oncology Impact Management LP | 2.16M (3.22%) | -672.00K Decreased by -31.11% | Dec 31, 24 |
| 19 | Holocene Advisors, LP | 2.13M (3.18%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 20 | Adage Capital Partners Gp LLC | 2.00M (2.98%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard US Total Market Shares ETF | 2.42M (3.60%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 2.36M (3.52%) | -51.67K Decreased by -2.19% | Jul 31, 25 |
| 3 | Franklin Biotechnology Discv A(acc)USD | 1.12M (1.68%) | -56.48K Decreased by -5.02% | Dec 31, 23 |
| 4 | Franklin Small Cap Growth Adv | 963.45K (1.44%) | -5.00K Decreased by -0.52% | Dec 31, 23 |
| 5 | Franklin US Small Cap Growth Equity | 963.45K (1.44%) | -5.00K Decreased by -0.52% | Dec 31, 23 |
| 6 | Baillie Gifford Global Discovery A Acc | 917.84K (1.37%) | 7.41K Increased by +0.81% | Oct 31, 24 |
| 7 | Fidelity Small Cap Index | 835.21K (1.24%) | -23.86K Decreased by -2.86% | May 31, 25 |
| 8 | Vanguard Institutional Extnd Mkt Idx Tr | 815.39K (1.21%) | -371.55K Decreased by -45.57% | Jul 31, 25 |
| 9 | Edinburgh Worldwide Ord | 750.73K (1.12%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 10 | iShares Russell 2000 Value ETF | 728.08K (1.08%) | 0.00 Increased by 0.00% | May 31, 25 |
| 11 | Fidelity® Small Cap Index | 562.81K (0.84%) | 14.30K Increased by +2.54% | Sep 30, 23 |
| 12 | Belfius Equities Cure C Cap | 550.37K (0.82%) | 0.00 Increased by 0.00% | Feb 29, 24 |
| 13 | Franklin Biotechnology Discovery A | 543.39K (0.81%) | -20.80K Decreased by -3.83% | Dec 31, 23 |
| 14 | State St Russell Sm/Mid Cp® Indx NL Cl C | 502.75K (0.75%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 15 | State St Russell Sm/Mid Cp® Indx SL Cl I | 502.75K (0.75%) | 0.00 Increased by 0.00% | May 31, 25 |
| 16 | iShares Biotechnology ETF | 481.13K (0.72%) | 4.11K Increased by +0.85% | Jul 31, 25 |
| 17 | Goldman Sachs Small Cp Val Insghts Instl | 467.61K (0.70%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 18 | Candriam Global Equities Oncology | 440.37K (0.66%) | -110.00K Decreased by -24.98% | Mar 31, 24 |
| 19 | Fidelity Extended Market Index | 409.73K (0.61%) | -1.07K Decreased by -0.26% | Jun 30, 25 |
| 20 | Vanguard Russell 2000 ETF | 409.49K (0.61%) | 3.66K Increased by +0.89% | May 31, 25 |