| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Suvretta Capital Management, LLC | 6.49M (62.98%) | -974.17K Decreased by -15.01% | Jun 30, 25 |
| 2 | Rubric Capital Management LP | 3.34M (32.47%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 3 | Franklin Resources Inc | 2.76M (26.82%) | -71.72K Decreased by -2.60% | Dec 31, 23 |
| 4 | Verition Fund Managegment, LLC | 2.50M (24.28%) | 555.02K Increased by +22.19% | Sep 30, 23 |
| 5 | Eversept Partners, LLC | 2.29M (22.25%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 6 | MPM Oncology Impact Management LP | 2.16M (20.97%) | -672.00K Decreased by -31.11% | Dec 31, 24 |
| 7 | Holocene Advisors, LP | 2.13M (20.70%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 8 | Parkman Healthcare Partners LLC | 1.73M (16.77%) | 11.79K Increased by +0.68% | Dec 31, 24 |
| 9 | Goldman Sachs Group Inc | 1.71M (16.62%) | -2.31K Decreased by -0.13% | Mar 31, 25 |
| 10 | Baillie Gifford & Co Limited. | 1.52M (14.75%) | -329.41K Decreased by -21.68% | Sep 30, 24 |
| 11 | Nuveen Asset Management, LLC | 1.32M (12.85%) | 124.15K Increased by +9.38% | Dec 31, 24 |
| 12 | Bvf Inc | 1.25M (12.15%) | 1.25M Increased by +100.00% | Mar 31, 26 |
| 13 | State Street Corporation | 1.20M (11.62%) | 35.26K Increased by +2.95% | Mar 31, 24 |
| 14 | Aquilo Capital Management, LLC | 1.17M (11.31%) | 744.82K Increased by +63.91% | Mar 31, 24 |
| 15 | Schonfeld Strategic Advisors LLC | 1.12M (10.90%) | 768.10K Increased by +68.39% | Mar 31, 24 |
| 16 | Affinity Asset Advisors, LLC | 1.07M (10.38%) | 321.14K Increased by +30.03% | Mar 31, 26 |
| 17 | Samsara BioCapital, LLC | 1.06M (10.32%) | 858.37K Increased by +80.76% | Mar 31, 26 |
| 18 | Panagora Asset Management Inc | 907.50K (8.81%) | 122.30K Increased by +13.48% | Jun 30, 24 |
| 19 | Candriam Luxembourg S.C.A. | 898.23K (8.72%) | -640.00K Decreased by -71.25% | Dec 31, 23 |
| 20 | Kynam Capital Management, LP | 872.56K (8.47%) | 392.97K Increased by +45.04% | Mar 31, 26 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard US Total Market Shares ETF | 2.42M (23.45%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 2 | Franklin Biotechnology Discv A(acc)USD | 1.12M (10.92%) | -56.48K Decreased by -5.02% | Dec 31, 23 |
| 3 | Franklin Small Cap Growth Adv | 963.45K (9.35%) | -5.00K Decreased by -0.52% | Dec 31, 23 |
| 4 | Franklin US Small Cap Growth Equity | 963.45K (9.35%) | -5.00K Decreased by -0.52% | Dec 31, 23 |
| 5 | Baillie Gifford Global Discovery A Acc | 917.84K (8.91%) | 7.41K Increased by +0.81% | Oct 31, 24 |
| 6 | Fidelity Small Cap Index | 835.21K (8.11%) | -23.86K Decreased by -2.86% | May 31, 25 |
| 7 | Edinburgh Worldwide Ord | 750.73K (7.29%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 8 | iShares Russell 2000 Value ETF | 728.08K (7.07%) | 0.00 Increased by 0.00% | May 31, 25 |
| 9 | Eventide Healthcare & Life Sciences I | 715.31K (6.94%) | 715.31K Increased by +100.00% | Mar 31, 26 |
| 10 | Fidelity® Small Cap Index | 562.81K (5.46%) | 14.30K Increased by +2.54% | Sep 30, 23 |
| 11 | Belfius Equities Cure C Cap | 550.37K (5.34%) | 0.00 Increased by 0.00% | Feb 29, 24 |
| 12 | Franklin Biotechnology Discovery A | 543.39K (5.27%) | -20.80K Decreased by -3.83% | Dec 31, 23 |
| 13 | Vanguard Total Stock Mkt Idx Inv | 533.12K (5.17%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 14 | State St Russell Sm/Mid Cp® Indx NL Cl C | 502.75K (4.88%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 15 | State St Russell Sm/Mid Cp® Indx SL Cl I | 502.75K (4.88%) | 0.00 Increased by 0.00% | May 31, 25 |
| 16 | Goldman Sachs Small Cp Val Insghts Instl | 467.61K (4.54%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 17 | iShares Biotechnology ETF | 467.05K (4.53%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 18 | Candriam Global Equities Oncology | 440.37K (4.27%) | -110.00K Decreased by -24.98% | Mar 31, 24 |
| 19 | Vanguard Russell 2000 ETF | 409.49K (3.97%) | 3.66K Increased by +0.89% | May 31, 25 |
| 20 | Vanguard US Value Factor ETF | 394.19K (3.83%) | 200.29K Increased by +50.81% | Jun 30, 25 |