| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 13.79M (17.41%) | 159.23K Increased by +1.15% | Mar 31, 25 |
| 2 | Artal Group S A | 11.26M (14.21%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 3 | Siren, L.L.C. | 9.25M (11.67%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 4 | T. Rowe Price Associates, Inc. | 8.89M (11.22%) | -389.54K Decreased by -4.38% | Mar 31, 25 |
| 5 | BlackRock Inc | 7.31M (9.22%) | 134.90K Increased by +1.85% | Mar 31, 25 |
| 6 | Samsara BioCapital, LLC | 5.61M (7.08%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 7 | Vanguard Group Inc | 4.85M (6.11%) | 101.72K Increased by +2.10% | Mar 31, 25 |
| 8 | Redmile Group, LLC | 4.55M (5.74%) | -688.96K Decreased by -15.14% | Dec 31, 24 |
| 9 | State Street Corporation | 4.17M (5.26%) | 2.01M Increased by +48.21% | Mar 31, 24 |
| 10 | State Street Corp | 3.13M (3.96%) | 494.85K Increased by +15.79% | Mar 31, 25 |
| 11 | Marshall Wace Asset Management Ltd | 2.95M (3.72%) | 2.73M Increased by +92.77% | Dec 31, 24 |
| 12 | Eventide Asset Management, LLC | 2.66M (3.36%) | 2.37K Increased by +0.09% | Mar 31, 25 |
| 13 | Polar Capital Holdings PLC | 2.58M (3.26%) | -125.00K Decreased by -4.84% | Mar 31, 25 |
| 14 | Bellevue Group AG | 2.51M (3.16%) | -3.80K Decreased by -0.15% | Mar 31, 25 |
| 15 | Adage Capital Partners Gp LLC | 2.02M (2.55%) | 423.13K Increased by +20.97% | Mar 31, 25 |
| 16 | NORGES BANK | 1.99M (2.51%) | 1.99M Increased by +100.00% | Dec 31, 24 |
| 17 | Fairmount Funds Management LLC | 1.96M (2.48%) | 1.96M Increased by +100.00% | Dec 31, 24 |
| 18 | Hood River Capital Management LLC | 1.94M (2.45%) | 45.52K Increased by +2.34% | Mar 31, 25 |
| 19 | Geode Capital Management, LLC | 1.85M (2.33%) | 77.13K Increased by +4.17% | Mar 31, 25 |
| 20 | Wellington Management Company LLP | 1.84M (2.33%) | 119.38K Increased by +6.47% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Fidelity Growth Compy Commingled Pl S | 4.82M (6.08%) | 38.66K Increased by +0.80% | Mar 31, 25 |
| 2 | T. Rowe Price New Horizons | 3.82M (4.82%) | -142.86K Decreased by -3.74% | Mar 31, 25 |
| 3 | US Small-Cap Growth II Equity Comp | 3.82M (4.82%) | -212.11K Decreased by -5.55% | Mar 31, 25 |
| 4 | Fidelity Growth Compy Commingled Pl O | 3.59M (4.53%) | 36.80K Increased by +1.02% | Aug 31, 24 |
| 5 | Fidelity Growth Company Fund | 3.47M (4.38%) | 76.29K Increased by +2.20% | Mar 31, 25 |
| 6 | Vanguard Total Stock Mkt Idx Inv | 2.74M (3.45%) | 52.85K Increased by +1.93% | Apr 30, 25 |
| 7 | BB Biotech AG Ord | 2.49M (3.14%) | 353.98K Increased by +14.23% | Dec 31, 24 |
| 8 | Fidelity® Select Biotechnology | 2.49M (3.14%) | 428.93K Increased by +17.25% | Nov 30, 23 |
| 9 | Polar Capital Biotech S Inc | 2.38M (3.00%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 10 | Vanguard US Total Market Shares ETF | 2.29M (2.90%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 11 | Fidelity® Growth Company | 2.19M (2.76%) | 66.00K Increased by +3.02% | Nov 30, 23 |
| 12 | T. Rowe Price Health Sciences | 2.03M (2.56%) | -121.77K Decreased by -6.01% | Mar 31, 25 |
| 13 | iShares Russell 2000 ETF | 1.98M (2.50%) | 335.00 Increased by +0.02% | Apr 30, 25 |
| 14 | Fidelity Advisor® Biotechnology I | 1.67M (2.10%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 15 | Fidelity Select Biotechnology | 1.63M (2.06%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 16 | Eventide Gilead N | 1.46M (1.84%) | 78.66K Increased by +5.38% | Dec 31, 24 |
| 17 | SPDR® S&P Biotech ETF | 1.33M (1.68%) | -19.55K Decreased by -1.46% | Apr 30, 25 |
| 18 | T. Rowe Price Integrated US SmCapGrEq | 1.25M (1.58%) | 624.53K Increased by +50.00% | Dec 31, 24 |
| 19 | Eventide Healthcare & Life Sciences I | 1.19M (1.50%) | 167.87K Increased by +14.12% | Dec 31, 24 |
| 20 | Vanguard Institutional Extnd Mkt Idx Tr | 1.14M (1.44%) | 9.10K Increased by +0.80% | Apr 30, 25 |