| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 9.03M (11.74%) | 794.90K Increased by +8.80% | Dec 31, 24 |
| 2 | Kynam Capital Management, LP | 8.52M (11.07%) | 2.68M Increased by +31.42% | Dec 31, 24 |
| 3 | Goldman Sachs Group Inc | 5.95M (7.73%) | 4.34M Increased by +72.91% | Dec 31, 24 |
| 4 | Morgan Stanley - Brokerage Accounts | 5.31M (6.91%) | 4.43M Increased by +83.30% | Dec 31, 24 |
| 5 | Vanguard Group Inc | 4.88M (6.35%) | -5.01K Decreased by -0.10% | Dec 31, 24 |
| 6 | State Street Corporation | 4.82M (6.26%) | -196.63K Decreased by -4.08% | Mar 31, 24 |
| 7 | Wellington Management Company LLP | 4.23M (5.50%) | -751.52K Decreased by -17.75% | Dec 31, 24 |
| 8 | Eversept Partners, LLC | 4.11M (5.34%) | 491.68K Increased by +11.98% | Sep 30, 24 |
| 9 | State Street Corp | 3.92M (5.09%) | 146.69K Increased by +3.74% | Dec 31, 24 |
| 10 | StemPoint Capital LP | 2.87M (3.73%) | 1.14M Increased by +39.73% | Dec 31, 24 |
| 11 | Partner Fund Management LP | 2.72M (3.53%) | 542.80K Increased by +19.99% | Sep 30, 23 |
| 12 | Soleus Capital Management, L.P. | 2.49M (3.24%) | 1.40M Increased by +56.22% | Dec 31, 24 |
| 13 | Hudson Bay Capital Management LP | 2.47M (3.21%) | 2.00M Increased by +80.79% | Sep 30, 23 |
| 14 | T. Rowe Price Investment Management,Inc. | 2.46M (3.20%) | -252.02K Decreased by -10.25% | Mar 31, 24 |
| 15 | Paradigm Biocapital Advisors LP | 2.39M (3.11%) | -34.05K Decreased by -1.42% | Sep 30, 23 |
| 16 | Jennison Associates LLC | 2.35M (3.05%) | -174.24K Decreased by -7.42% | Sep 30, 23 |
| 17 | venBio Select Advisor LLC | 2.27M (2.96%) | -1.61M Decreased by -70.92% | Dec 31, 24 |
| 18 | Sofinnova Ventures | 2.15M (2.80%) | 545.13K Increased by +25.31% | Jun 30, 24 |
| 19 | Assenagon Asset Management SA | 2.06M (2.68%) | 1.60M Increased by +77.43% | Dec 31, 24 |
| 20 | Kingdon Capital Management LLC | 2.00M (2.60%) | 1.00M Increased by +50.00% | Dec 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Health Care Inv | 2.99M (3.88%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 2.55M (3.32%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 3 | iShares Russell 2000 ETF | 2.15M (2.80%) | -18.64K Decreased by -0.87% | Mar 31, 25 |
| 4 | SPDR® S&P Biotech ETF | 2.10M (2.73%) | -22.52K Decreased by -1.07% | Mar 31, 25 |
| 5 | Vanguard Institutional Extnd Mkt Idx Tr | 1.29M (1.68%) | 2.04K Increased by +0.16% | Feb 28, 25 |
| 6 | Eventide Healthcare & Life Sciences I | 1.18M (1.53%) | 391.07K Increased by +33.20% | Dec 31, 24 |
| 7 | Franklin Biotechnology Discv A(acc)USD | 814.51K (1.06%) | 81.30K Increased by +9.98% | Feb 28, 25 |
| 8 | Fidelity Small Cap Index | 809.22K (1.05%) | -15.15K Decreased by -1.87% | Jan 31, 25 |
| 9 | iShares Russell 2000 Growth ETF | 724.33K (0.94%) | -3.44K Decreased by -0.48% | Mar 31, 25 |
| 10 | Franklin Small Cap Growth Adv | 703.28K (0.91%) | 136.70K Increased by +19.44% | Feb 28, 25 |
| 11 | BNP Paribas Health Cr Innovtr Cl Cap | 671.95K (0.87%) | -91.00 Decreased by -0.01% | Feb 28, 25 |
| 12 | Fidelity® Small Cap Index | 634.70K (0.82%) | 15.84K Increased by +2.50% | Oct 31, 23 |
| 13 | Wellington Global Hlthcr Eq USD G Ac | 633.83K (0.82%) | -13.65K Decreased by -2.15% | May 31, 24 |
| 14 | Biotech Growth Ord | 612.09K (0.80%) | -25.11K Decreased by -4.10% | Oct 31, 24 |
| 15 | T. Rowe Price Small-Cap Value | 607.50K (0.79%) | -270.60K Decreased by -44.54% | Mar 31, 24 |
| 16 | Franklin US Small Cap Growth Equity | 566.58K (0.74%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 17 | BNP Paribas US Small Cap Classic R | 549.50K (0.71%) | 38.85K Increased by +7.07% | Feb 28, 25 |
| 18 | iShares Biotechnology ETF | 533.39K (0.69%) | -5.94K Decreased by -1.11% | Mar 31, 25 |
| 19 | Federated Hermes Kaufmann Growth | 522.40K (0.68%) | 272.40K Increased by +52.14% | Sep 30, 24 |
| 20 | Federated Hermes Kaufmann R | 522.40K (0.68%) | 272.40K Increased by +52.14% | Sep 30, 24 |