| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Baker Bros Advisors LP | 33.72M (27.03%) | 9.30M Increased by +27.57% | Jun 30, 25 |
| 2 | FMR Inc | 9.23M (7.39%) | -111.85K Decreased by -1.21% | Jun 30, 25 |
| 3 | Vanguard Group Inc | 8.67M (6.95%) | -2.97M Decreased by -34.21% | Jun 30, 25 |
| 4 | State Street Corporation | 8.11M (6.50%) | 5.66M Increased by +69.73% | Mar 31, 24 |
| 5 | BlackRock Inc | 6.85M (5.49%) | -1.55M Decreased by -22.65% | Jun 30, 25 |
| 6 | State Street Corp | 4.02M (3.22%) | -833.69K Decreased by -20.75% | Jun 30, 25 |
| 7 | T. Rowe Price Associates, Inc. | 3.91M (3.13%) | -2.65M Decreased by -67.93% | Jun 30, 25 |
| 8 | Geode Capital Management, LLC | 2.93M (2.35%) | -350.07K Decreased by -11.93% | Jun 30, 25 |
| 9 | Pictet Asset Manangement SA | 2.16M (1.73%) | -497.73K Decreased by -23.00% | Jun 30, 25 |
| 10 | UBS Group AG | 2.09M (1.68%) | 829.74K Increased by +39.63% | Jun 30, 25 |
| 11 | Balyasny Asset Management LLC | 1.70M (1.36%) | 1.32M Increased by +77.26% | Mar 31, 25 |
| 12 | NORGES BANK | 1.39M (1.11%) | 1.29M Increased by +92.81% | Jun 30, 25 |
| 13 | Charles Schwab Investment Management Inc | 1.29M (1.04%) | -169.05K Decreased by -13.09% | Jun 30, 25 |
| 14 | abrdn PLC | 1.29M (1.03%) | 154.14K Increased by +11.94% | Dec 31, 24 |
| 15 | APEIRON CAPITAL Ltd | 1.20M (0.96%) | 1.20M Increased by +100.00% | Jun 30, 25 |
| 16 | Aberdeen Group PLC | 1.14M (0.91%) | -61.28K Decreased by -5.38% | Jun 30, 25 |
| 17 | BNP Paribas Arbitrage, SA | 1.10M (0.88%) | 605.30K Increased by +55.10% | Mar 31, 25 |
| 18 | Darwin Global Management, Ltd. | 1.08M (0.87%) | 1.08M Increased by +100.00% | Sep 30, 24 |
| 19 | Polar Capital Holdings PLC | 1.00M (0.80%) | 1.00M Increased by +100.00% | Jun 30, 25 |
| 20 | Citadel Advisors Llc | 998.74K (0.80%) | 811.33K Increased by +81.24% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | T. Rowe Price Health Sciences | 3.11M (2.49%) | 365.22K Increased by +11.73% | Jul 31, 25 |
| 2 | Fidelity Growth Compy Commingled Pl S | 2.72M (2.18%) | 26.86K Increased by +0.99% | Jul 31, 25 |
| 3 | SPDR® S&P Biotech ETF | 2.43M (1.95%) | 5.41K Increased by +0.22% | Aug 31, 25 |
| 4 | Vanguard Total Stock Mkt Idx Inv | 2.37M (1.90%) | -50.74K Decreased by -2.15% | Jul 31, 25 |
| 5 | iShares Russell 2000 ETF | 2.31M (1.85%) | 0.00 Increased by 0.00% | May 31, 25 |
| 6 | Fidelity Growth Company Fund | 2.09M (1.67%) | 6.27K Increased by +0.30% | Jul 31, 25 |
| 7 | Vanguard Small Cap Index | 1.80M (1.44%) | -12.15K Decreased by -0.67% | Jul 31, 25 |
| 8 | Fidelity Select Biotechnology | 1.63M (1.31%) | -55.10K Decreased by -3.38% | Jul 31, 25 |
| 9 | Vanguard Institutional Extnd Mkt Idx Tr | 1.52M (1.22%) | -660.32K Decreased by -43.53% | Jul 31, 25 |
| 10 | Vanguard Small Cap Value Index Inv | 1.16M (0.93%) | -1.02K Decreased by -0.09% | Jul 31, 25 |
| 11 | Fidelity® Small Cap Index | 1.12M (0.89%) | 29.95K Increased by +2.69% | Oct 31, 23 |
| 12 | Polar Capital Biotech S Inc | 1.00M (0.80%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 13 | Fidelity Small Cap Index | 932.02K (0.75%) | 2.56K Increased by +0.28% | May 31, 25 |
| 14 | iShares Russell Mid-Cap Growth ETF | 779.26K (0.62%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 15 | Fidelity Extended Market Index | 763.51K (0.61%) | 7.05K Increased by +0.92% | Jul 31, 25 |
| 16 | iShares Russell 2000 Growth ETF | 755.44K (0.61%) | 0.00 Increased by 0.00% | May 31, 25 |
| 17 | Fidelity Advisor Health Care I | 750.00K (0.60%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 18 | abrdn Healthcare Investors | 745.67K (0.60%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 19 | Fidelity Growth Compy Commingled Pl O | 721.52K (0.58%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 20 | Pictet-Biotech P USD | 720.64K (0.58%) | 8.82K Increased by +1.22% | May 31, 25 |