| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Baker Bros Advisors LP | 24.42M (21.97%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | Vanguard Group Inc | 11.67M (10.50%) | 724.04K Increased by +6.20% | Dec 31, 24 |
| 3 | BlackRock Inc | 8.43M (7.58%) | 336.84K Increased by +3.99% | Dec 31, 24 |
| 4 | State Street Corporation | 8.11M (7.30%) | 5.66M Increased by +69.73% | Mar 31, 24 |
| 5 | FMR Inc | 8.06M (7.25%) | -247.75K Decreased by -3.08% | Dec 31, 24 |
| 6 | T. Rowe Price Associates, Inc. | 6.56M (5.90%) | 1.12M Increased by +17.05% | Dec 31, 24 |
| 7 | State Street Corp | 5.60M (5.04%) | 2.13M Increased by +38.09% | Dec 31, 24 |
| 8 | Geode Capital Management, LLC | 3.20M (2.88%) | 101.04K Increased by +3.16% | Dec 31, 24 |
| 9 | Millennium Management LLC | 2.05M (1.84%) | 827.48K Increased by +40.37% | Dec 31, 24 |
| 10 | Charles Schwab Investment Management Inc | 1.49M (1.34%) | 52.36K Increased by +3.53% | Dec 31, 24 |
| 11 | Pictet Asset Manangement SA | 1.39M (1.25%) | 695.84K Increased by +50.16% | Dec 31, 24 |
| 12 | Aberdeen Group PLC | 1.29M (1.16%) | 154.14K Increased by +11.94% | Dec 31, 24 |
| 13 | abrdn PLC | 1.29M (1.16%) | 154.14K Increased by +11.94% | Dec 31, 24 |
| 14 | UBS Group AG | 1.19M (1.07%) | 1.07M Increased by +89.90% | Dec 31, 24 |
| 15 | Darwin Global Management, Ltd. | 1.08M (0.98%) | 1.08M Increased by +100.00% | Sep 30, 24 |
| 16 | Rock Springs Capital Management LP | 1.05M (0.95%) | 14.00K Increased by +1.33% | Dec 31, 24 |
| 17 | Anson Funds Management LP | 941.91K (0.85%) | 941.91K Increased by +100.00% | Jun 30, 24 |
| 18 | Goldman Sachs Group Inc | 910.00K (0.82%) | 414.65K Increased by +45.57% | Dec 31, 24 |
| 19 | Northern Trust Corp | 871.40K (0.78%) | 14.07K Increased by +1.62% | Dec 31, 24 |
| 20 | Candriam Luxembourg S.C.A. | 842.55K (0.76%) | -7.85K Decreased by -0.93% | Dec 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 3.50M (3.15%) | 11.61K Increased by +0.33% | Mar 31, 25 |
| 2 | Vanguard Small Cap Index | 2.76M (2.48%) | -66.03K Decreased by -2.39% | Mar 31, 25 |
| 3 | SPDR® S&P Biotech ETF | 2.74M (2.46%) | -48.03K Decreased by -1.75% | Apr 30, 25 |
| 4 | Fidelity Growth Compy Commingled Pl S | 2.29M (2.06%) | 142.50K Increased by +6.21% | Mar 31, 25 |
| 5 | Fidelity Select Biotechnology | 2.29M (2.06%) | -283.40K Decreased by -12.38% | Feb 28, 25 |
| 6 | iShares Russell 2000 ETF | 2.27M (2.05%) | -18.43K Decreased by -0.81% | Apr 29, 25 |
| 7 | Vanguard Institutional Extnd Mkt Idx Tr | 2.16M (1.94%) | 23.82K Increased by +1.10% | Mar 31, 25 |
| 8 | Vanguard Small Cap Value Index Inv | 1.79M (1.61%) | -69.57K Decreased by -3.89% | Mar 31, 25 |
| 9 | Fidelity Growth Company Fund | 1.67M (1.50%) | 340.10K Increased by +20.34% | Feb 28, 25 |
| 10 | Fidelity® Small Cap Index | 1.12M (1.00%) | 29.95K Increased by +2.69% | Oct 31, 23 |
| 11 | Pictet-Biotech P USD | 994.23K (0.89%) | 512.18K Increased by +51.52% | Jan 31, 25 |
| 12 | Fidelity Small Cap Index | 911.69K (0.82%) | 4.27K Increased by +0.47% | Feb 28, 25 |
| 13 | abrdn Healthcare Investors | 788.56K (0.71%) | -50.33K Decreased by -6.38% | Mar 31, 25 |
| 14 | Fidelity Extended Market Index | 776.05K (0.70%) | 13.69K Increased by +1.76% | Mar 31, 25 |
| 15 | iShares Russell 2000 Growth ETF | 774.50K (0.70%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 16 | Fidelity Advisor Health Care I | 750.00K (0.67%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 17 | Pictet-Global Megatrend Sel I USD | 728.17K (0.65%) | 728.17K Increased by +100.00% | Jan 31, 25 |
| 18 | iShares Biotechnology ETF | 723.86K (0.65%) | 1.66K Increased by +0.23% | Apr 30, 25 |
| 19 | Fidelity Growth Compy Commingled Pl O | 721.52K (0.65%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 20 | Fidelity® Extended Market Index | 672.34K (0.60%) | 20.68K Increased by +3.08% | Nov 30, 23 |