| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Baker Bros Advisors LP | 24.42M (21.97%) | 1.20M Increased by +4.92% | Sep 30, 24 |
| 2 | Vanguard Group Inc | 10.95M (9.85%) | 2.13M Increased by +19.44% | Sep 30, 24 |
| 3 | FMR Inc | 8.30M (7.47%) | 737.69K Increased by +8.88% | Sep 30, 24 |
| 4 | State Street Corporation | 8.11M (7.30%) | 5.66M Increased by +69.73% | Mar 31, 24 |
| 5 | BlackRock Inc | 8.09M (7.28%) | 196.10K Increased by +2.42% | Sep 30, 24 |
| 6 | T. Rowe Price Associates, Inc. | 5.44M (4.89%) | 3.40M Increased by +62.46% | Sep 30, 24 |
| 7 | State Street Corp | 3.47M (3.12%) | -654.62K Decreased by -18.87% | Sep 30, 24 |
| 8 | Geode Capital Management, LLC | 3.10M (2.79%) | 135.98K Increased by +4.39% | Sep 30, 24 |
| 9 | Charles Schwab Investment Management Inc | 1.43M (1.29%) | 497.98K Increased by +34.76% | Sep 30, 24 |
| 10 | abrdn PLC | 1.29M (1.16%) | 154.14K Increased by +11.94% | Dec 31, 24 |
| 11 | Millennium Management LLC | 1.22M (1.10%) | -720.51K Decreased by -58.95% | Sep 30, 24 |
| 12 | Darwin Global Management, Ltd. | 1.08M (0.98%) | 1.08M Increased by +100.00% | Sep 30, 24 |
| 13 | Rock Springs Capital Management LP | 1.04M (0.94%) | 1.04M Increased by +100.00% | Sep 30, 24 |
| 14 | Anson Funds Management LP | 941.91K (0.85%) | 941.91K Increased by +100.00% | Jun 30, 24 |
| 15 | Northern Trust Corp | 857.33K (0.77%) | -102.98K Decreased by -12.01% | Sep 30, 24 |
| 16 | Candriam Luxembourg S.C.A. | 850.40K (0.76%) | 850.40K Increased by +100.00% | Sep 30, 24 |
| 17 | First Trust Advisors L.P. | 788.07K (0.71%) | 788.07K Increased by +100.00% | Jun 30, 24 |
| 18 | TD Asset Management Inc | 694.72K (0.62%) | 427.92K Increased by +61.60% | Sep 30, 24 |
| 19 | Pictet Asset Manangement SA | 691.40K (0.62%) | -17.22K Decreased by -2.49% | Sep 30, 24 |
| 20 | Citadel Advisors Llc | 650.83K (0.59%) | 650.83K Increased by +100.00% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 3.45M (3.11%) | 51.98K Increased by +1.51% | Dec 31, 24 |
| 2 | SPDR® S&P Biotech ETF | 3.39M (3.05%) | -12.57K Decreased by -0.37% | Jan 30, 25 |
| 3 | Vanguard Small Cap Index | 2.82M (2.53%) | 77.62K Increased by +2.76% | Dec 31, 24 |
| 4 | Fidelity Select Biotechnology | 2.79M (2.51%) | -247.70K Decreased by -8.87% | Dec 31, 24 |
| 5 | iShares Russell 2000 ETF | 2.51M (2.26%) | -381.00 Decreased by -0.02% | Jan 29, 25 |
| 6 | Vanguard Institutional Extnd Mkt Idx Tr | 2.13M (1.91%) | 68.75K Increased by +3.23% | Dec 31, 24 |
| 7 | Vanguard Small Cap Value Index Inv | 1.87M (1.68%) | 18.84K Increased by +1.01% | Dec 31, 24 |
| 8 | Fidelity® Small Cap Index | 1.12M (1.00%) | 29.95K Increased by +2.69% | Oct 31, 23 |
| 9 | Fidelity Growth Compy Commingled Pl S | 949.33K (0.85%) | 10.07K Increased by +1.06% | Dec 31, 24 |
| 10 | Fidelity Small Cap Index | 887.71K (0.80%) | -5.93K Decreased by -0.67% | Nov 30, 24 |
| 11 | abrdn Healthcare Investors | 852.28K (0.77%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 12 | iShares Russell 2000 Growth ETF | 784.18K (0.71%) | 0.00 Increased by 0.00% | Jan 29, 25 |
| 13 | Fidelity Extended Market Index | 776.36K (0.70%) | 12.67K Increased by +1.63% | Dec 31, 24 |
| 14 | Fidelity Advisor Health Care I | 750.00K (0.67%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 15 | Fidelity Growth Compy Commingled Pl O | 721.52K (0.65%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 16 | Fidelity Growth Company Fund | 698.99K (0.63%) | -17.41K Decreased by -2.49% | Dec 31, 24 |
| 17 | Schwab US Small-Cap ETF™ | 677.26K (0.61%) | -864.00 Decreased by -0.13% | Jan 30, 25 |
| 18 | Fidelity® Extended Market Index | 672.34K (0.60%) | 20.68K Increased by +3.08% | Nov 30, 23 |
| 19 | iShares Biotechnology ETF | 655.37K (0.59%) | 3.47K Increased by +0.53% | Jan 29, 25 |
| 20 | Candriam Eqs L Biotech C USD Cap | 639.83K (0.58%) | 0.00 Increased by 0.00% | Dec 31, 24 |