| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Baker Bros Advisors LP | 24.42M (21.05%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 2 | Vanguard Group Inc | 11.64M (10.03%) | -30.07K Decreased by -0.26% | Mar 31, 25 |
| 3 | FMR Inc | 9.34M (8.05%) | 1.28M Increased by +13.74% | Mar 31, 25 |
| 4 | BlackRock Inc | 8.40M (7.24%) | -33.97K Decreased by -0.40% | Mar 31, 25 |
| 5 | State Street Corporation | 8.11M (6.99%) | 5.66M Increased by +69.73% | Mar 31, 24 |
| 6 | T. Rowe Price Associates, Inc. | 6.56M (5.65%) | -123.00 Decreased by -0.00% | Mar 31, 25 |
| 7 | State Street Corp | 4.85M (4.18%) | -751.52K Decreased by -15.49% | Mar 31, 25 |
| 8 | Geode Capital Management, LLC | 3.28M (2.83%) | 84.03K Increased by +2.56% | Mar 31, 25 |
| 9 | Pictet Asset Manangement SA | 2.66M (2.29%) | 1.27M Increased by +47.88% | Mar 31, 25 |
| 10 | Balyasny Asset Management LLC | 1.70M (1.47%) | 1.32M Increased by +77.26% | Mar 31, 25 |
| 11 | Charles Schwab Investment Management Inc | 1.46M (1.26%) | -24.36K Decreased by -1.67% | Mar 31, 25 |
| 12 | abrdn PLC | 1.29M (1.11%) | 154.14K Increased by +11.94% | Dec 31, 24 |
| 13 | UBS Group AG | 1.26M (1.09%) | 77.87K Increased by +6.16% | Mar 31, 25 |
| 14 | Aberdeen Group PLC | 1.14M (0.98%) | -61.28K Decreased by -5.38% | Jun 30, 25 |
| 15 | BNP Paribas Arbitrage, SA | 1.10M (0.95%) | 605.30K Increased by +55.10% | Mar 31, 25 |
| 16 | Darwin Global Management, Ltd. | 1.08M (0.93%) | 1.08M Increased by +100.00% | Sep 30, 24 |
| 17 | Citadel Advisors Llc | 998.74K (0.86%) | 811.33K Increased by +81.24% | Mar 31, 25 |
| 18 | Rock Springs Capital Management LP | 995.00K (0.86%) | -59.00K Decreased by -5.93% | Mar 31, 25 |
| 19 | Anson Funds Management LP | 941.91K (0.81%) | 941.91K Increased by +100.00% | Jun 30, 24 |
| 20 | Millennium Management LLC | 887.01K (0.76%) | -1.16M Decreased by -131.09% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | T. Rowe Price Health Sciences | 2.75M (2.37%) | -103.45K Decreased by -3.77% | Jun 30, 25 |
| 2 | Fidelity Growth Compy Commingled Pl S | 2.69M (2.32%) | 103.64K Increased by +3.85% | Jun 30, 25 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 2.42M (2.08%) | -1.14M Decreased by -47.06% | Jun 30, 25 |
| 4 | SPDR® S&P Biotech ETF | 2.41M (2.08%) | 59.51K Increased by +2.47% | Jul 31, 25 |
| 5 | iShares Russell 2000 ETF | 2.31M (1.99%) | 0.00 Increased by 0.00% | May 31, 25 |
| 6 | Vanguard Institutional Extnd Mkt Idx Tr | 2.18M (1.88%) | -5.49K Decreased by -0.25% | Jun 30, 25 |
| 7 | Fidelity Growth Company Fund | 2.08M (1.79%) | 81.80K Increased by +3.93% | Jun 30, 25 |
| 8 | Vanguard Small Cap Index | 1.81M (1.56%) | -979.67K Decreased by -54.01% | Jun 30, 25 |
| 9 | Fidelity Select Biotechnology | 1.69M (1.45%) | -40.00K Decreased by -2.37% | Jun 30, 25 |
| 10 | Vanguard Small Cap Value Index Inv | 1.16M (1.00%) | -636.38K Decreased by -54.96% | Jun 30, 25 |
| 11 | Fidelity® Small Cap Index | 1.12M (0.96%) | 29.95K Increased by +2.69% | Oct 31, 23 |
| 12 | Polar Capital Biotech S Inc | 1.00M (0.86%) | 813.85K Increased by +81.39% | Jun 30, 25 |
| 13 | Fidelity Small Cap Index | 932.02K (0.80%) | 2.56K Increased by +0.28% | May 31, 25 |
| 14 | iShares Russell Mid-Cap Growth ETF | 780.90K (0.67%) | 0.00 Increased by 0.00% | Jul 30, 25 |
| 15 | Fidelity Extended Market Index | 756.46K (0.65%) | -8.44K Decreased by -1.12% | Jun 30, 25 |
| 16 | iShares Russell 2000 Growth ETF | 755.44K (0.65%) | 0.00 Increased by 0.00% | May 31, 25 |
| 17 | Fidelity Advisor Health Care I | 750.00K (0.65%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 18 | abrdn Healthcare Investors | 745.67K (0.64%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 19 | Fidelity Growth Compy Commingled Pl O | 721.52K (0.62%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 20 | Pictet-Global Megatrend Sel I USD | 716.00K (0.62%) | -2.03K Decreased by -0.28% | Mar 31, 25 |