| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Baker Bros Advisors LP | 24.42M (21.05%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 2 | Vanguard Group Inc | 11.64M (10.03%) | -30.07K Decreased by -0.26% | Mar 31, 25 |
| 3 | FMR Inc | 9.34M (8.05%) | 1.28M Increased by +13.74% | Mar 31, 25 |
| 4 | BlackRock Inc | 8.40M (7.24%) | -33.97K Decreased by -0.40% | Mar 31, 25 |
| 5 | State Street Corporation | 8.11M (6.99%) | 5.66M Increased by +69.73% | Mar 31, 24 |
| 6 | T. Rowe Price Associates, Inc. | 6.56M (5.65%) | -123.00 Decreased by -0.00% | Mar 31, 25 |
| 7 | State Street Corp | 4.85M (4.18%) | -751.52K Decreased by -15.49% | Mar 31, 25 |
| 8 | Geode Capital Management, LLC | 3.28M (2.83%) | 84.03K Increased by +2.56% | Mar 31, 25 |
| 9 | Pictet Asset Manangement SA | 2.66M (2.29%) | 1.27M Increased by +47.88% | Mar 31, 25 |
| 10 | Balyasny Asset Management LLC | 1.70M (1.47%) | 1.32M Increased by +77.26% | Mar 31, 25 |
| 11 | Charles Schwab Investment Management Inc | 1.46M (1.26%) | -24.36K Decreased by -1.67% | Mar 31, 25 |
| 12 | abrdn PLC | 1.29M (1.11%) | 154.14K Increased by +11.94% | Dec 31, 24 |
| 13 | Aberdeen Group PLC | 1.20M (1.03%) | -89.61K Decreased by -7.46% | Mar 31, 25 |
| 14 | UBS Group AG | 1.19M (1.02%) | 1.07M Increased by +89.90% | Dec 31, 24 |
| 15 | BNP Paribas Arbitrage, SA | 1.10M (0.95%) | 605.30K Increased by +55.10% | Mar 31, 25 |
| 16 | Darwin Global Management, Ltd. | 1.08M (0.93%) | 1.08M Increased by +100.00% | Sep 30, 24 |
| 17 | Citadel Advisors Llc | 998.74K (0.86%) | 811.33K Increased by +81.24% | Mar 31, 25 |
| 18 | Rock Springs Capital Management LP | 995.00K (0.86%) | -59.00K Decreased by -5.93% | Mar 31, 25 |
| 19 | Anson Funds Management LP | 941.91K (0.81%) | 941.91K Increased by +100.00% | Jun 30, 24 |
| 20 | Millennium Management LLC | 887.01K (0.76%) | -1.16M Decreased by -131.09% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 3.55M (3.06%) | 52.99K Increased by +1.49% | Apr 30, 25 |
| 2 | Vanguard Small Cap Index | 2.78M (2.39%) | 19.69K Increased by +0.71% | Apr 30, 25 |
| 3 | SPDR® S&P Biotech ETF | 2.64M (2.28%) | 15.64K Increased by +0.59% | May 31, 25 |
| 4 | Fidelity Growth Compy Commingled Pl S | 2.40M (2.07%) | 111.10K Increased by +4.62% | Apr 30, 25 |
| 5 | iShares Russell 2000 ETF | 2.31M (1.99%) | 0.00 Increased by 0.00% | May 31, 25 |
| 6 | Vanguard Institutional Extnd Mkt Idx Tr | 2.17M (1.87%) | 11.89K Increased by +0.55% | Apr 30, 25 |
| 7 | Fidelity Select Biotechnology | 2.16M (1.86%) | -89.80K Decreased by -4.16% | Apr 30, 25 |
| 8 | Fidelity Growth Company Fund | 1.86M (1.60%) | 76.30K Increased by +4.11% | Apr 30, 25 |
| 9 | Vanguard Small Cap Value Index Inv | 1.80M (1.55%) | 5.67K Increased by +0.32% | Apr 30, 25 |
| 10 | Fidelity® Small Cap Index | 1.12M (0.96%) | 29.95K Increased by +2.69% | Oct 31, 23 |
| 11 | Pictet-Biotech P USD | 956.79K (0.82%) | -37.44K Decreased by -3.91% | Feb 28, 25 |
| 12 | Fidelity Small Cap Index | 918.73K (0.79%) | 7.04K Increased by +0.77% | Mar 31, 25 |
| 13 | Fidelity Extended Market Index | 780.67K (0.67%) | 4.62K Increased by +0.59% | Apr 30, 25 |
| 14 | iShares Russell 2000 Growth ETF | 755.44K (0.65%) | 0.00 Increased by 0.00% | May 31, 25 |
| 15 | Fidelity Advisor Health Care I | 750.00K (0.65%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 16 | abrdn Healthcare Investors | 745.67K (0.64%) | -42.88K Decreased by -5.75% | May 31, 25 |
| 17 | Fidelity Growth Compy Commingled Pl O | 721.52K (0.62%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 18 | Pictet-Global Megatrend Sel I USD | 718.02K (0.62%) | -10.15K Decreased by -1.41% | Feb 28, 25 |
| 19 | iShares Biotechnology ETF | 679.14K (0.59%) | 0.00 Increased by 0.00% | May 31, 25 |
| 20 | Fidelity® Extended Market Index | 672.34K (0.58%) | 20.68K Increased by +3.08% | Nov 30, 23 |