| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 6.85M (13.31%) | -95.96K Decreased by -1.40% | Mar 31, 25 |
| 2 | RA Capital Management, LLC | 6.08M (11.81%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 3 | PRIMECAP Management Company | 5.79M (11.23%) | -783.87K Decreased by -13.54% | Mar 31, 25 |
| 4 | Baker Bros Advisors LP | 5.60M (10.88%) | -479.77K Decreased by -8.56% | Mar 31, 25 |
| 5 | Vanguard Group Inc | 3.44M (6.69%) | 2.33K Increased by +0.07% | Mar 31, 25 |
| 6 | State Street Corporation | 3.01M (5.85%) | 807.82K Increased by +26.80% | Mar 31, 24 |
| 7 | NEA Management Company, LLC | 2.91M (5.65%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 8 | Perceptive Advisors LLC | 2.55M (4.95%) | -1.13M Decreased by -44.42% | Mar 31, 25 |
| 9 | State Street Corp | 1.97M (3.83%) | 129.86K Increased by +6.59% | Mar 31, 25 |
| 10 | FMR Inc | 1.69M (3.28%) | 1.58M Increased by +93.30% | Mar 31, 25 |
| 11 | HHG PLC | 1.66M (3.21%) | 435.80K Increased by +26.33% | Mar 31, 25 |
| 12 | Goldman Sachs Group Inc | 1.64M (3.18%) | -174.30K Decreased by -10.64% | Mar 31, 25 |
| 13 | Federated Hermes Inc | 1.59M (3.09%) | 42.24K Increased by +2.65% | Mar 31, 25 |
| 14 | Polar Capital Holdings PLC | 1.50M (2.91%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 15 | Driehaus Capital Management LLC | 1.46M (2.83%) | 167.05K Increased by +11.46% | Mar 31, 25 |
| 16 | Westfield Capital Management Company, L.P. | 1.34M (2.60%) | 1.34M Increased by +100.00% | Mar 31, 25 |
| 17 | Geode Capital Management, LLC | 1.29M (2.50%) | 31.37K Increased by +2.44% | Mar 31, 25 |
| 18 | T. Rowe Price Associates, Inc. | 1.20M (2.33%) | 513.90K Increased by +42.86% | Mar 31, 25 |
| 19 | HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | 1.11M (2.16%) | 143.80K Increased by +12.94% | Sep 30, 24 |
| 20 | VR Adviser, LLC | 1.09M (2.12%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | PRIMECAP Odyssey Aggressive Growth | 3.87M (7.51%) | -604.46K Decreased by -15.62% | Mar 31, 25 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 1.97M (3.82%) | 32.66K Increased by +1.66% | Apr 30, 25 |
| 3 | Vanguard US Total Market Shares ETF | 1.92M (3.72%) | 2.33K Increased by +0.12% | Sep 30, 24 |
| 4 | PRIMECAP Odyssey Growth | 1.64M (3.18%) | -165.10K Decreased by -10.07% | Mar 31, 25 |
| 5 | iShares Russell 2000 ETF | 1.35M (2.62%) | 228.00 Increased by +0.02% | Apr 30, 25 |
| 6 | Vanguard Institutional Extnd Mkt Idx Tr | 812.54K (1.58%) | 996.00 Increased by +0.12% | Apr 30, 25 |
| 7 | Fidelity® Select Biotechnology | 786.90K (1.53%) | -75.80K Decreased by -9.63% | Nov 30, 23 |
| 8 | Federated Hermes Kaufmann Small Cap A | 740.07K (1.44%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 9 | Federated Hermes Kaufmann Small Cap Grow | 740.07K (1.44%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 10 | Federated Hermes Kaufmann Growth | 691.29K (1.34%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 11 | Federated Hermes Kaufmann R | 691.29K (1.34%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 12 | BlackRock Health Sciences Opps Inv A | 690.35K (1.34%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 13 | SPDR® S&P Biotech ETF | 690.14K (1.34%) | -10.12K Decreased by -1.47% | Apr 30, 25 |
| 14 | BGF World Healthscience A2 | 679.21K (1.32%) | 0.00 Increased by 0.00% | Jan 31, 25 |
| 15 | Pictet Biotech | 659.88K (1.28%) | 659.88K Increased by +100.00% | Mar 31, 24 |
| 16 | BlackRock Health Sciences Term Trust | 630.46K (1.22%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 17 | ACAP Strategic A | 576.14K (1.12%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 18 | Fidelity Small Cap Index | 543.04K (1.05%) | 3.04K Increased by +0.56% | Feb 28, 25 |
| 19 | Fidelity Select Biotechnology | 517.40K (1.00%) | -269.50K Decreased by -52.09% | Dec 31, 23 |
| 20 | Polar Capital Biotech S Inc | 500.00K (0.97%) | -750.00K Decreased by -150.00% | Mar 31, 25 |