| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 6.27M (11.40%) | -587.22K Decreased by -9.37% | Jun 30, 25 |
| 2 | Baker Bros Advisors LP | 5.60M (10.19%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 3 | RA Capital Management, LLC | 5.56M (10.11%) | -523.05K Decreased by -9.41% | Jun 30, 25 |
| 4 | PRIMECAP Management Company | 4.88M (8.87%) | -909.28K Decreased by -18.64% | Jun 30, 25 |
| 5 | Vanguard Group Inc | 3.59M (6.53%) | 144.19K Increased by +4.02% | Jun 30, 25 |
| 6 | State Street Corporation | 3.01M (5.48%) | 807.82K Increased by +26.80% | Mar 31, 24 |
| 7 | NEA Management Company, LLC | 2.91M (5.29%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 8 | Perceptive Advisors LLC | 2.42M (4.40%) | -130.15K Decreased by -5.38% | Jun 30, 25 |
| 9 | FMR Inc | 1.95M (3.55%) | 265.07K Increased by +13.57% | Jun 30, 25 |
| 10 | State Street Corp | 1.91M (3.47%) | -63.13K Decreased by -3.31% | Jun 30, 25 |
| 11 | Goldman Sachs Group Inc | 1.73M (3.15%) | 95.81K Increased by +5.53% | Jun 30, 25 |
| 12 | Federated Hermes Inc | 1.69M (3.07%) | 94.62K Increased by +5.61% | Jun 30, 25 |
| 13 | Westfield Capital Management Company, L.P. | 1.63M (2.96%) | 288.38K Increased by +17.70% | Jun 30, 25 |
| 14 | HHG PLC | 1.41M (2.57%) | -243.45K Decreased by -17.24% | Jun 30, 25 |
| 15 | T. Rowe Price Associates, Inc. | 1.34M (2.44%) | 142.34K Increased by +10.61% | Jun 30, 25 |
| 16 | Geode Capital Management, LLC | 1.31M (2.38%) | 24.09K Increased by +1.84% | Jun 30, 25 |
| 17 | Driehaus Capital Management LLC | 1.27M (2.31%) | -188.07K Decreased by -14.81% | Jun 30, 25 |
| 18 | Polar Capital Holdings PLC | 1.25M (2.27%) | 750.87K Increased by +60.03% | Jun 30, 25 |
| 19 | HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | 1.11M (2.02%) | 143.80K Increased by +12.94% | Sep 30, 24 |
| 20 | VR Adviser, LLC | 1.09M (1.98%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | PRIMECAP Odyssey Aggressive Growth | 3.09M (5.62%) | -779.65K Decreased by -25.22% | Jun 30, 25 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 2.02M (3.68%) | -51.22K Decreased by -2.53% | Jul 31, 25 |
| 3 | Vanguard US Total Market Shares ETF | 1.92M (3.49%) | 2.33K Increased by +0.12% | Sep 30, 24 |
| 4 | PRIMECAP Odyssey Growth | 1.53M (2.78%) | -111.43K Decreased by -7.29% | Jun 30, 25 |
| 5 | iShares Russell 2000 ETF | 1.31M (2.39%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 6 | Polar Capital Biotech S Inc | 1.25M (2.27%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 7 | Fidelity® Select Biotechnology | 786.90K (1.43%) | -75.80K Decreased by -9.63% | Nov 30, 23 |
| 8 | Federated Hermes Kaufmann Small Cap A | 742.00K (1.35%) | 1.93K Increased by +0.26% | Jun 30, 25 |
| 9 | Federated Hermes Kaufmann Small Cap Grow | 742.00K (1.35%) | 1.93K Increased by +0.26% | Jun 30, 25 |
| 10 | Federated Hermes Kaufmann Growth | 733.00K (1.33%) | 41.70K Increased by +5.69% | Jun 30, 25 |
| 11 | Federated Hermes Kaufmann R | 733.00K (1.33%) | 41.70K Increased by +5.69% | Jun 30, 25 |
| 12 | BlackRock Health Sciences Opps Inv A | 690.35K (1.26%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 13 | BGF World Healthscience A2 USD | 679.21K (1.23%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 14 | Pictet Biotech | 659.88K (1.20%) | 659.88K Increased by +100.00% | Mar 31, 24 |
| 15 | BlackRock Health Sciences Term Trust | 630.46K (1.15%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 16 | SPDR® S&P Biotech ETF | 630.00K (1.15%) | 1.41K Increased by +0.22% | Aug 31, 25 |
| 17 | BGF World Healthscience A2 | 611.43K (1.11%) | -67.78K Decreased by -11.09% | May 31, 25 |
| 18 | Vanguard Institutional Extnd Mkt Idx Tr | 580.85K (1.06%) | -255.43K Decreased by -43.98% | Jul 31, 25 |
| 19 | Fidelity Small Cap Growth | 577.39K (1.05%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 20 | Fidelity Small Cap Index | 545.84K (0.99%) | -8.76K Decreased by -1.60% | Jun 30, 25 |