| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 6.95M (14.80%) | 61.46K Increased by +0.88% | Dec 31, 24 |
| 2 | PRIMECAP Management Company | 6.57M (13.99%) | -645.72K Decreased by -9.83% | Dec 31, 24 |
| 3 | RA Capital Management, LLC | 6.08M (12.95%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 4 | Baker Bros Advisors LP | 6.08M (12.95%) | -314.12K Decreased by -5.16% | Dec 31, 24 |
| 5 | Perceptive Advisors LLC | 3.68M (7.83%) | 120.26K Increased by +3.27% | Dec 31, 24 |
| 6 | Vanguard Group Inc | 3.44M (7.33%) | -5.31K Decreased by -0.15% | Dec 31, 24 |
| 7 | State Street Corporation | 3.01M (6.42%) | 807.82K Increased by +26.80% | Mar 31, 24 |
| 8 | NEA Management Company, LLC | 2.91M (6.19%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 9 | State Street Corp | 1.84M (3.92%) | -152.30K Decreased by -8.27% | Dec 31, 24 |
| 10 | Goldman Sachs Group Inc | 1.81M (3.86%) | -2.07M Decreased by -114.09% | Dec 31, 24 |
| 11 | Federated Hermes Inc | 1.55M (3.30%) | -114.27K Decreased by -7.37% | Dec 31, 24 |
| 12 | Polar Capital Holdings PLC | 1.50M (3.19%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 13 | Driehaus Capital Management LLC | 1.29M (2.75%) | -8.52K Decreased by -0.66% | Dec 31, 24 |
| 14 | Geode Capital Management, LLC | 1.26M (2.67%) | -389.00 Decreased by -0.03% | Dec 31, 24 |
| 15 | HHG PLC | 1.22M (2.60%) | 621.43K Increased by +50.96% | Dec 31, 24 |
| 16 | Alkeon Capital Management, LLC | 1.17M (2.49%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 17 | Rock Springs Capital Management LP | 1.16M (2.48%) | -65.38K Decreased by -5.62% | Dec 31, 24 |
| 18 | HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | 1.11M (2.37%) | 143.80K Increased by +12.94% | Sep 30, 24 |
| 19 | VR Adviser, LLC | 1.09M (2.32%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 20 | Morgan Stanley - Brokerage Accounts | 951.30K (2.03%) | 585.56K Increased by +61.55% | Jun 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | PRIMECAP Odyssey Aggressive Growth | 4.48M (9.53%) | -314.92K Decreased by -7.04% | Dec 31, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 1.93M (4.10%) | 1.55K Increased by +0.08% | Feb 28, 25 |
| 3 | PRIMECAP Odyssey Growth | 1.81M (3.84%) | -284.97K Decreased by -15.79% | Dec 31, 24 |
| 4 | iShares Russell 2000 ETF | 1.44M (3.06%) | -12.43K Decreased by -0.87% | Mar 31, 25 |
| 5 | Polar Capital Biotech S Inc | 1.25M (2.66%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 6 | Vanguard Institutional Extnd Mkt Idx Tr | 790.27K (1.68%) | 1.16K Increased by +0.15% | Feb 28, 25 |
| 7 | Fidelity® Select Biotechnology | 786.90K (1.68%) | -75.80K Decreased by -9.63% | Nov 30, 23 |
| 8 | Federated Hermes Kaufmann Small Cap A | 740.07K (1.58%) | -59.93K Decreased by -8.10% | Dec 31, 24 |
| 9 | Federated Hermes Kaufmann Small Cap Grow | 740.07K (1.58%) | -59.93K Decreased by -8.10% | Dec 31, 24 |
| 10 | SPDR® S&P Biotech ETF | 707.28K (1.51%) | -7.59K Decreased by -1.07% | Mar 31, 25 |
| 11 | Federated Hermes Kaufmann Growth | 691.29K (1.47%) | -148.71K Decreased by -21.51% | Dec 31, 24 |
| 12 | Federated Hermes Kaufmann R | 691.29K (1.47%) | -148.71K Decreased by -21.51% | Dec 31, 24 |
| 13 | BlackRock Health Sciences Opps Inv A | 690.35K (1.47%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 14 | BGF World Healthscience A2 | 679.21K (1.45%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 15 | Pictet Biotech | 659.88K (1.40%) | 659.88K Increased by +100.00% | Mar 31, 24 |
| 16 | BlackRock Health Sciences Term Trust | 630.46K (1.34%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 17 | Fidelity Small Cap Index | 539.99K (1.15%) | -10.11K Decreased by -1.87% | Jan 31, 25 |
| 18 | Fidelity Select Biotechnology | 517.40K (1.10%) | -269.50K Decreased by -52.09% | Dec 31, 23 |
| 19 | Janus Henderson Global Life Sciences | 500.00K (1.06%) | -2.06K Decreased by -0.41% | Sep 30, 23 |
| 20 | Janus Henderson Global Life Sciences D | 500.00K (1.06%) | -2.06K Decreased by -0.41% | Sep 30, 23 |