| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RA Capital Management, LLC | 6.67M (11.98%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 2 | BlackRock Inc | 6.24M (11.20%) | -60.18K Decreased by -0.96% | Mar 31, 26 |
| 3 | Vanguard Group Inc | 6.21M (11.16%) | 1.21M Increased by +19.55% | Dec 31, 25 |
| 4 | Baker Bros Advisors LP | 5.60M (10.07%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 5 | PRIMECAP Management Company | 3.42M (6.14%) | -61.16K Decreased by -1.79% | Mar 31, 26 |
| 6 | Vanguard Portfolio Management, LLC | 3.04M (5.46%) | 3.04M Increased by +100.00% | Mar 31, 26 |
| 7 | State Street Corporation | 3.01M (5.41%) | 807.82K Increased by +26.80% | Mar 31, 24 |
| 8 | Vanguard Capital Management, LLC | 2.97M (5.33%) | 2.97M Increased by +100.00% | Mar 31, 26 |
| 9 | NEA Management Company, LLC | 2.91M (5.23%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 10 | Perceptive Advisors LLC | 2.37M (4.26%) | -172.60K Decreased by -7.27% | Mar 31, 26 |
| 11 | State Street Corp | 2.27M (4.08%) | 73.24K Increased by +3.22% | Mar 31, 26 |
| 12 | The Goldman Sachs Group Inc | 1.97M (3.53%) | 134.57K Increased by +6.85% | Mar 31, 26 |
| 13 | Westfield Capital Management Company, L.P. | 1.93M (3.47%) | 661.97K Increased by +34.31% | Mar 31, 26 |
| 14 | Goldman Sachs Group Inc | 1.73M (3.11%) | 95.81K Increased by +5.53% | Jun 30, 25 |
| 15 | FMR Inc | 1.69M (3.04%) | -16.65K Decreased by -0.99% | Mar 31, 26 |
| 16 | T. Rowe Price Associates, Inc. | 1.65M (2.97%) | 94.03K Increased by +5.68% | Mar 31, 26 |
| 17 | Polar Capital Holdings PLC | 1.62M (2.90%) | 430.19K Increased by +26.63% | Mar 31, 26 |
| 18 | JPMorgan Chase & Co | 1.55M (2.79%) | 129.66K Increased by +8.35% | Mar 31, 26 |
| 19 | Citadel Advisors Llc | 1.42M (2.55%) | 1.27M Increased by +89.19% | Mar 31, 26 |
| 20 | Geode Capital Management, LLC | 1.42M (2.54%) | 40.54K Increased by +2.86% | Mar 31, 26 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 2.18M (3.92%) | 6.32K Increased by +0.29% | Apr 30, 26 |
| 2 | PRIMECAP Odyssey Aggressive Growth | 2.12M (3.82%) | -32.46K Decreased by -1.53% | Mar 31, 26 |
| 3 | Vanguard US Total Market Shares ETF | 1.92M (3.45%) | 2.33K Increased by +0.12% | Sep 30, 24 |
| 4 | Vanguard Small Cap Index | 1.57M (2.83%) | -3.16K Decreased by -0.20% | Apr 30, 26 |
| 5 | Polar Capital Biotech S Inc | 1.53M (2.74%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 6 | iShares Russell 2000 ETF | 1.27M (2.27%) | 11.70K Increased by +0.92% | May 29, 26 |
| 7 | American Funds SMALLCAP World A | 1.12M (2.01%) | 132.37K Increased by +11.82% | Mar 31, 26 |
| 8 | PRIMECAP Odyssey Growth | 1.11M (1.99%) | -29.40K Decreased by -2.66% | Mar 31, 26 |
| 9 | State Street® SPDR® S&P® Biotech ETF | 1.04M (1.87%) | -6.41K Decreased by -0.61% | May 31, 26 |
| 10 | Vanguard Small Cap Growth Index Inv | 882.31K (1.58%) | -574.00 Decreased by -0.07% | Apr 30, 26 |
| 11 | Fidelity® Select Biotechnology | 786.90K (1.41%) | -75.80K Decreased by -9.63% | Nov 30, 23 |
| 12 | Vanguard Institutional Extnd Mkt Idx Tr | 684.87K (1.23%) | 6.05K Increased by +0.88% | Apr 30, 26 |
| 13 | BGF World Healthscience A2 USD | 679.21K (1.22%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 14 | Pictet Biotech | 659.88K (1.19%) | 659.88K Increased by +100.00% | Mar 31, 24 |
| 15 | BlackRock Health Sciences Term Trust | 630.46K (1.13%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 16 | SPDR® S&P Biotech ETF | 630.00K (1.13%) | 1.41K Increased by +0.22% | Aug 31, 25 |
| 17 | JPM US Mid Cap Growth-Composite | 597.19K (1.07%) | 117.03K Increased by +19.60% | Mar 31, 26 |
| 18 | JPMorgan Mid Cap Growth I | 594.00K (1.07%) | -3.19K Decreased by -0.54% | Apr 30, 26 |
| 19 | Federated Hermes Kaufmann Small Cap A | 592.00K (1.06%) | -81.00K Decreased by -13.68% | Mar 31, 26 |
| 20 | Federated Hermes Kaufmann Small Cap Grow | 592.00K (1.06%) | -81.00K Decreased by -13.68% | Mar 31, 26 |