| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 6.89M (15.23%) | 147.34K Increased by +2.14% | Sep 30, 24 |
| 2 | PRIMECAP Management Company | 6.57M (14.53%) | -645.72K Decreased by -9.83% | Dec 31, 24 |
| 3 | RA Capital Management, LLC | 6.08M (13.45%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 4 | Baker Bros Advisors LP | 6.08M (13.45%) | -314.12K Decreased by -5.16% | Dec 31, 24 |
| 5 | Goldman Sachs Group Inc | 3.88M (8.58%) | -1.41M Decreased by -36.31% | Sep 30, 24 |
| 6 | Perceptive Advisors LLC | 3.56M (7.87%) | 113.64K Increased by +3.19% | Sep 30, 24 |
| 7 | Vanguard Group Inc | 3.44M (7.61%) | -5.31K Decreased by -0.15% | Dec 31, 24 |
| 8 | State Street Corporation | 3.01M (6.66%) | 807.82K Increased by +26.80% | Mar 31, 24 |
| 9 | NEA Management Company, LLC | 2.91M (6.43%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 10 | State Street Corp | 1.99M (4.41%) | -10.72K Decreased by -0.54% | Sep 30, 24 |
| 11 | Federated Hermes Inc | 1.66M (3.68%) | 3.12K Increased by +0.19% | Sep 30, 24 |
| 12 | Polar Capital Holdings PLC | 1.50M (3.32%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 13 | Driehaus Capital Management LLC | 1.30M (2.87%) | 117.12K Increased by +9.01% | Sep 30, 24 |
| 14 | Geode Capital Management, LLC | 1.26M (2.78%) | 3.50K Increased by +0.28% | Sep 30, 24 |
| 15 | Rock Springs Capital Management LP | 1.23M (2.72%) | -52.40K Decreased by -4.27% | Sep 30, 24 |
| 16 | Alkeon Capital Management, LLC | 1.17M (2.58%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 17 | HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | 1.11M (2.46%) | 143.80K Increased by +12.94% | Sep 30, 24 |
| 18 | VR Adviser, LLC | 1.09M (2.41%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 19 | Morgan Stanley - Brokerage Accounts | 951.30K (2.10%) | 585.56K Increased by +61.55% | Jun 30, 24 |
| 20 | FMR Inc | 868.47K (1.92%) | 166.94K Increased by +19.22% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | PRIMECAP Odyssey Aggressive Growth | 4.48M (9.90%) | -314.92K Decreased by -7.04% | Dec 31, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 1.91M (4.23%) | 12.64K Increased by +0.66% | Dec 31, 24 |
| 3 | PRIMECAP Odyssey Growth | 1.81M (3.99%) | -284.97K Decreased by -15.79% | Dec 31, 24 |
| 4 | Polar Capital Biotech S Inc | 1.50M (3.32%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 5 | iShares Russell 2000 ETF | 1.49M (3.29%) | -11.30K Decreased by -0.76% | Jan 31, 25 |
| 6 | Vanguard Institutional Extnd Mkt Idx Tr | 788.90K (1.74%) | 1.96K Increased by +0.25% | Dec 31, 24 |
| 7 | Fidelity® Select Biotechnology | 786.90K (1.74%) | -75.80K Decreased by -9.63% | Nov 30, 23 |
| 8 | Federated Hermes Kaufmann Small Cap A | 740.07K (1.64%) | -59.93K Decreased by -8.10% | Dec 31, 24 |
| 9 | Federated Hermes Kaufmann Small Cap Grow | 740.07K (1.64%) | -59.93K Decreased by -8.10% | Dec 31, 24 |
| 10 | Federated Hermes Kaufmann Growth | 691.29K (1.53%) | -148.71K Decreased by -21.51% | Dec 31, 24 |
| 11 | Federated Hermes Kaufmann R | 691.29K (1.53%) | -148.71K Decreased by -21.51% | Dec 31, 24 |
| 12 | BlackRock Health Sciences Opps Inv A | 690.35K (1.53%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 13 | Pictet Biotech | 659.88K (1.46%) | 659.88K Increased by +100.00% | Mar 31, 24 |
| 14 | BGF World Healthscience A2 | 652.77K (1.44%) | 0.00 Increased by 0.00% | Oct 31, 24 |
| 15 | BlackRock Health Sciences Term Trust | 630.46K (1.39%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 16 | Fidelity Small Cap Index | 555.12K (1.23%) | -4.71K Decreased by -0.85% | Nov 30, 24 |
| 17 | SPDR® S&P Biotech ETF | 536.70K (1.19%) | -12.18K Decreased by -2.27% | Jan 31, 25 |
| 18 | Fidelity Select Biotechnology | 517.40K (1.14%) | -269.50K Decreased by -52.09% | Dec 31, 23 |
| 19 | Janus Henderson Global Life Sciences | 500.00K (1.11%) | -2.06K Decreased by -0.41% | Sep 30, 23 |
| 20 | Janus Henderson Global Life Sciences D | 500.00K (1.11%) | -2.06K Decreased by -0.41% | Sep 30, 23 |