| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 2.33M (24.86%) | -5.79K Decreased by -0.25% | Jun 30, 25 |
| 2 | State Street Corporation | 2.20M (23.45%) | 168.59K Increased by +7.66% | Dec 31, 23 |
| 3 | OUP Management Co., LLC | 862.54K (9.19%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 4 | CM Management, LLC | 700.00K (7.45%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 5 | MPM Oncology Impact Management LP | 686.01K (7.31%) | -104.77K Decreased by -15.27% | Jun 30, 25 |
| 6 | BlackRock Inc | 653.84K (6.96%) | -19.21K Decreased by -2.94% | Jun 30, 25 |
| 7 | Siren, L.L.C. | 563.27K (6.00%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 8 | DZ BANK AG Deutsche Zentral-Genossenschaftsbank Frankfurt am Main | 528.04K (5.62%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 9 | Vanguard Group Inc | 496.37K (5.29%) | -7.17K Decreased by -1.44% | Jun 30, 25 |
| 10 | Endurant Capital Management LP | 453.31K (4.83%) | -232.83K Decreased by -51.36% | Sep 30, 23 |
| 11 | Artal Group S A | 304.55K (3.24%) | 304.55K Increased by +100.00% | Jun 30, 24 |
| 12 | Erste Asset Management GmbH | 260.01K (2.77%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 13 | 683 Capital Management LLC | 219.00K (2.33%) | 69.00K Increased by +31.51% | Jun 30, 25 |
| 14 | Geode Capital Management, LLC | 218.93K (2.33%) | -6.57K Decreased by -3.00% | Jun 30, 25 |
| 15 | JPMorgan Chase & Co | 195.04K (2.08%) | -79.70K Decreased by -40.87% | Mar 31, 25 |
| 16 | State Street Corp | 194.27K (2.07%) | -6.86K Decreased by -3.53% | Jun 30, 25 |
| 17 | Logos Global Management LP | 180.00K (1.92%) | 180.00K Increased by +100.00% | Jun 30, 24 |
| 18 | Citadel Advisors Llc | 120.87K (1.29%) | -26.42K Decreased by -21.86% | Jun 30, 25 |
| 19 | Yale University | 100.00K (1.06%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 20 | Armistice Capital, LLC | 98.56K (1.05%) | 98.56K Increased by +100.00% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Fidelity® Select Biotechnology | 5.39M (57.35%) | 2.96M Increased by +55.05% | Nov 30, 23 |
| 2 | JPM Thematics Genetic Thrps C2 Acc USD | 1.38M (14.66%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 3 | Fidelity® Small Cap Index | 1.10M (11.73%) | 20.74K Increased by +1.88% | Oct 31, 23 |
| 4 | Fidelity Select Biotechnology | 665.75K (7.09%) | -10.20K Decreased by -1.53% | Jul 31, 25 |
| 5 | Fidelity® Extended Market Index | 555.52K (5.92%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 6 | Vanguard Explorer Inv | 528.84K (5.63%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 7 | Fidelity Growth Compy Commingled Pl S | 462.91K (4.93%) | 500.00 Increased by +0.11% | Jul 31, 25 |
| 8 | HBM Healthcare Investments AG Ord | 415.23K (4.42%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 9 | Vanguard VIF Small Co Gr | 414.81K (4.42%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 10 | Fidelity Select Health Care | 368.99K (3.93%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 11 | Fidelity Growth Company Fund | 341.34K (3.64%) | 300.00 Increased by +0.09% | Jul 31, 25 |
| 12 | Nuveen Equity Index R6 | 330.58K (3.52%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 13 | TIAA-CREF Equity Index Instl | 330.58K (3.52%) | 0.00 Increased by 0.00% | Jan 31, 24 |
| 14 | BlackRock Extended Mkt Composite | 310.20K (3.30%) | 2.03K Increased by +0.66% | Sep 30, 23 |
| 15 | Bridgeway Ultra-Small Company Market | 285.00K (3.04%) | -150.00K Decreased by -52.63% | Mar 31, 24 |
| 16 | Vanguard Total Stock Mkt Idx Inv | 281.78K (3.00%) | -6.21K Decreased by -2.20% | Jul 31, 25 |
| 17 | BlackRock Extended Equity Market K | 267.73K (2.85%) | 96.00 Increased by +0.04% | Mar 31, 24 |
| 18 | NT R2000 Value Index Fund - NL | 261.51K (2.78%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 19 | NT R2000 Index Fund - DC - NL - 2 | 260.15K (2.77%) | -12.44K Decreased by -4.78% | Mar 31, 24 |
| 20 | iShares Russell 2000 ETF | 239.73K (2.55%) | 0.00 Increased by 0.00% | Aug 31, 25 |