| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Squadron Capital Management LLC | 6.70M (10.24%) | 6.70M Increased by +100.00% | Dec 31, 25 |
| 2 | Adage Capital Partners Gp LLC | 4.27M (6.52%) | 4.27M Increased by +100.00% | Dec 31, 25 |
| 3 | Spruce Street Capital LP | 4.09M (6.24%) | 4.09M Increased by +100.00% | Dec 31, 25 |
| 4 | Marshall Wace Asset Management Ltd | 3.19M (4.87%) | 2.92M Increased by +91.47% | Dec 31, 25 |
| 5 | Ikarian Capital, LLC | 3.07M (4.69%) | 1.23M Increased by +39.93% | Dec 31, 25 |
| 6 | Orbimed Advisors, LLC | 2.61M (3.99%) | 2.61M Increased by +100.00% | Dec 31, 25 |
| 7 | RTW INVESTMENTS, LLC | 2.13M (3.26%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 8 | Driehaus Capital Management LLC | 1.88M (2.87%) | 1.14M Increased by +60.64% | Dec 31, 25 |
| 9 | Millennium Management LLC | 1.67M (2.56%) | 1.67M Increased by +100.00% | Dec 31, 25 |
| 10 | BRAIDWELL LP | 1.58M (2.42%) | 1.58M Increased by +100.00% | Dec 31, 25 |
| 11 | CI Private Wealth LLC | 1.44M (2.20%) | 1.23M Increased by +85.64% | Dec 31, 25 |
| 12 | Vanguard Group Inc | 1.20M (1.84%) | 784.73K Increased by +65.21% | Dec 31, 25 |
| 13 | Opaleye Management Inc | 935.00K (1.43%) | 935.00K Increased by +100.00% | Dec 31, 25 |
| 14 | Geode Capital Management, LLC | 854.93K (1.31%) | 558.72K Increased by +65.35% | Dec 31, 25 |
| 15 | BOOTHBAY FUND MANAGEMENT, LLC | 835.30K (1.28%) | 142.06K Increased by +17.01% | Dec 31, 25 |
| 16 | Deep Track Capital, LP | 674.83K (1.03%) | -559.94K Decreased by -82.97% | Sep 30, 24 |
| 17 | Acadian Asset Management LLC | 582.54K (0.89%) | 582.54K Increased by +100.00% | Sep 30, 25 |
| 18 | Two Sigma Investments LLC | 572.84K (0.88%) | 399.22K Increased by +69.69% | Dec 31, 25 |
| 19 | Balyasny Asset Management LLC | 547.85K (0.84%) | 547.85K Increased by +100.00% | Dec 31, 25 |
| 20 | BlackRock Inc | 508.00K (0.78%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Biotech Growth Ord | 1.52M (2.32%) | 1.52M Increased by +100.00% | Nov 30, 25 |
| 2 | Vanguard US Total Market Shares ETF | 851.92K (1.30%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 3 | Vanguard Institutional Extnd Mkt Idx Tr | 808.69K (1.24%) | 9.72K Increased by +1.20% | Feb 28, 26 |
| 4 | Vanguard Total Stock Mkt Idx Inv | 803.29K (1.23%) | -48.63K Decreased by -6.05% | Mar 31, 25 |
| 5 | Franklin Biotechnology Discv A(acc)USD | 623.80K (0.95%) | -221.90K Decreased by -35.57% | Feb 28, 25 |
| 6 | Fidelity Extended Market Index | 386.50K (0.59%) | -3.36K Decreased by -0.87% | Jan 31, 26 |
| 7 | AdvisorShares Psychedelics ETF | 338.87K (0.52%) | 0.00 Increased by 0.00% | Feb 27, 26 |
| 8 | Franklin Biotechnology Discovery A | 336.31K (0.51%) | -120.09K Decreased by -35.71% | Feb 28, 25 |
| 9 | Horizons Psychedelic Stock ETF | 227.04K (0.35%) | -36.13K Decreased by -15.91% | Feb 29, 24 |
| 10 | IMC US Ultra Micro Cap | 197.93K (0.30%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 11 | Blackrock Extended Mkt Fund CF | 192.46K (0.29%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 12 | Extended Equity Market Fund K | 165.07K (0.25%) | 117.75K Increased by +71.33% | Dec 31, 25 |
| 13 | Fidelity Total Market Index | 144.34K (0.22%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 14 | Fidelity® Extended Market Index | 128.41K (0.20%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 15 | Fidelity Series Total Market Index | 116.05K (0.18%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 16 | T. Rowe Price Health Sciences | 110.67K (0.17%) | -3.15K Decreased by -2.84% | Sep 30, 23 |
| 17 | Spartan Extended Market Index Pool F | 101.85K (0.16%) | 1.61K Increased by +1.58% | Jan 31, 26 |
| 18 | Bridgeway Ultra-Small Company | 100.18K (0.15%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 19 | Pleiades Small Cap Equity A | 98.97K (0.15%) | 98.97K Increased by +100.00% | Dec 31, 25 |
| 20 | Fidelity Enhanced Small Cap ETF | 91.17K (0.14%) | 0.00 Increased by 0.00% | Nov 26, 24 |