| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Baker Bros Advisors LP | 11.05M (20.91%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 2 | T. Rowe Price Associates, Inc. | 10.82M (20.48%) | -34.62K Decreased by -0.32% | Jun 30, 25 |
| 3 | State Street Corporation | 6.49M (12.28%) | 1.38M Increased by +21.20% | Mar 31, 24 |
| 4 | BlackRock Inc | 5.73M (10.85%) | -331.51K Decreased by -5.79% | Jun 30, 25 |
| 5 | Redmile Group, LLC | 4.66M (8.83%) | -233.74K Decreased by -5.01% | Jun 30, 25 |
| 6 | FCPM III SERVICES BV | 3.91M (7.40%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 7 | Vanguard Group Inc | 3.47M (6.57%) | -363.35K Decreased by -10.47% | Jun 30, 25 |
| 8 | TANG CAPITAL MANAGEMENT LLC | 3.20M (6.06%) | 300.00K Increased by +9.38% | Jun 30, 25 |
| 9 | State Street Corp | 2.45M (4.64%) | 54.64K Increased by +2.23% | Jun 30, 25 |
| 10 | Boxer Capital Management, LLC | 2.21M (4.19%) | 415.00K Increased by +18.77% | Jun 30, 25 |
| 11 | HHG PLC | 2.17M (4.10%) | 2.15M Increased by +99.17% | Sep 30, 23 |
| 12 | Bvf Inc | 2.14M (4.06%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 13 | RTW INVESTMENTS, LLC | 2.07M (3.91%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 14 | Omega Fund Management LLC | 1.98M (3.74%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 15 | Marshall Wace Asset Management Ltd | 1.87M (3.53%) | -621.16K Decreased by -33.28% | Jun 30, 25 |
| 16 | Sofinnova Ventures | 1.81M (3.42%) | -673.41K Decreased by -37.28% | Jun 30, 25 |
| 17 | Geode Capital Management, LLC | 1.62M (3.07%) | -48.72K Decreased by -3.00% | Jun 30, 25 |
| 18 | Boxer Capital LLC | 1.54M (2.91%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 19 | BRAIDWELL LP | 1.46M (2.77%) | -15.28K Decreased by -1.04% | Mar 31, 25 |
| 20 | Camber Capital Management LLC | 1.35M (2.56%) | -1.40M Decreased by -103.70% | Jun 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | US Small-Cap Growth II Equity Comp | 4.21M (7.98%) | -451.47K Decreased by -10.71% | Jun 30, 25 |
| 2 | T. Rowe Price New Horizons | 4.21M (7.96%) | -7.08K Decreased by -0.17% | Jul 31, 25 |
| 3 | Vanguard US Total Market Shares ETF | 2.02M (3.83%) | 478.00K Increased by +23.62% | Sep 30, 24 |
| 4 | T. Rowe Price Health Sciences | 1.73M (3.27%) | -165.39K Decreased by -9.56% | Jul 31, 25 |
| 5 | Vanguard Total Stock Mkt Idx Inv | 1.71M (3.23%) | -37.82K Decreased by -2.22% | Jul 31, 25 |
| 6 | T. Rowe Price Integrated US Sm Gr Eq | 1.60M (3.03%) | 117.60K Increased by +7.35% | Jul 31, 25 |
| 7 | iShares Russell 2000 ETF | 1.58M (2.99%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 8 | T. Rowe Price Integrated US SmCapGrEq | 1.48M (2.81%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 9 | T. Rowe Price New Horizons Tr-A | 1.30M (2.46%) | 21.57K Increased by +1.66% | Jun 30, 25 |
| 10 | T. Rowe Price New Horizons Tr-Z | 1.28M (2.42%) | 1.80K Increased by +0.14% | Mar 31, 25 |
| 11 | Fidelity Select Biotechnology | 1.00M (1.89%) | 797.79K Increased by +79.72% | Jul 31, 25 |
| 12 | SPDR® S&P Biotech ETF | 968.96K (1.83%) | 2.17K Increased by +0.22% | Aug 31, 25 |
| 13 | Fidelity® Select Biotechnology | 825.12K (1.56%) | -31.60K Decreased by -3.83% | Nov 30, 23 |
| 14 | Vanguard Institutional Extnd Mkt Idx Tr | 715.03K (1.35%) | -306.05K Decreased by -42.80% | Jul 31, 25 |
| 15 | Fidelity Small Cap Index | 660.96K (1.25%) | -33.31K Decreased by -5.04% | Jun 30, 25 |
| 16 | Janus Henderson Global Life Sciences | 638.89K (1.21%) | 638.89K Increased by +100.00% | Sep 30, 23 |
| 17 | Janus Henderson Global Life Sciences D | 638.89K (1.21%) | 638.89K Increased by +100.00% | Sep 30, 23 |
| 18 | Candriam Global Equities Oncology | 612.16K (1.16%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 19 | iShares Russell 2000 Value ETF | 587.25K (1.11%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 20 | Nuveen Quant Small Cap Equity R6 | 509.32K (0.96%) | -12.67K Decreased by -2.49% | Apr 30, 25 |