| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Baker Bros Advisors LP | 11.05M (25.20%) | 1.00M Increased by +9.05% | Sep 30, 24 |
| 2 | T. Rowe Price Associates, Inc. | 9.88M (22.54%) | 643.19K Increased by +6.51% | Sep 30, 24 |
| 3 | State Street Corporation | 6.49M (14.80%) | 1.38M Increased by +21.20% | Mar 31, 24 |
| 4 | BlackRock Inc | 5.47M (12.48%) | 757.77K Increased by +13.85% | Sep 30, 24 |
| 5 | FCPM III SERVICES BV | 4.87M (11.10%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 6 | Redmile Group, LLC | 4.78M (10.91%) | -780.91K Decreased by -16.33% | Sep 30, 24 |
| 7 | Vanguard Group Inc | 3.47M (7.91%) | 571.13K Increased by +16.48% | Sep 30, 24 |
| 8 | BRAIDWELL LP | 3.07M (7.01%) | 2.06M Increased by +67.00% | Sep 30, 24 |
| 9 | Omega Fund Management LLC | 2.46M (5.62%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 10 | State Street Corp | 2.34M (5.34%) | 1.18M Increased by +50.52% | Sep 30, 24 |
| 11 | HHG PLC | 2.17M (4.94%) | 2.15M Increased by +99.17% | Sep 30, 23 |
| 12 | Bvf Inc | 2.14M (4.89%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 13 | Morgan Stanley - Brokerage Accounts | 1.69M (3.86%) | -1.78M Decreased by -105.43% | Sep 30, 24 |
| 14 | Boxer Capital LLC | 1.54M (3.51%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 15 | Geode Capital Management, LLC | 1.43M (3.26%) | 217.31K Increased by +15.21% | Sep 30, 24 |
| 16 | Camber Capital Management LLC | 1.35M (3.08%) | -1.40M Decreased by -103.70% | Jun 30, 24 |
| 17 | Loomis, Sayles & Company LP | 1.29M (2.94%) | 103.22K Increased by +8.00% | Sep 30, 23 |
| 18 | TANG CAPITAL MANAGEMENT LLC | 1.20M (2.74%) | 394.56K Increased by +32.88% | Sep 30, 24 |
| 19 | Citadel Advisors Llc | 1.20M (2.73%) | 60.92K Increased by +5.09% | Sep 30, 23 |
| 20 | Millennium Management LLC | 1.15M (2.64%) | -1.96M Decreased by -170.00% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | T. Rowe Price New Horizons | 4.73M (10.79%) | 340.18K Increased by +7.19% | Nov 30, 24 |
| 2 | US Small-Cap Growth II Equity Comp | 4.39M (10.02%) | -15.52K Decreased by -0.35% | Sep 30, 24 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 1.99M (4.54%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 4 | T. Rowe Price Health Sciences | 1.72M (3.92%) | 230.10K Increased by +13.38% | Nov 30, 24 |
| 5 | iShares Russell 2000 ETF | 1.63M (3.73%) | -6.28K Decreased by -0.38% | Dec 31, 24 |
| 6 | T. Rowe Price Integrated US Sm Gr Eq | 1.48M (3.38%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 7 | T. Rowe Price Integrated US SmCapGrEq | 1.34M (3.05%) | 766.00K Increased by +57.23% | Sep 30, 24 |
| 8 | T. Rowe Price New Horizons Tr-Z | 1.28M (2.91%) | 274.81K Increased by +21.52% | Dec 31, 24 |
| 9 | Vanguard Institutional Extnd Mkt Idx Tr | 888.12K (2.03%) | 22.41K Increased by +2.52% | Dec 31, 24 |
| 10 | SPDR® S&P Biotech ETF | 875.28K (2.00%) | -15.60K Decreased by -1.78% | Dec 31, 24 |
| 11 | Fidelity® Select Biotechnology | 825.12K (1.88%) | -31.60K Decreased by -3.83% | Nov 30, 23 |
| 12 | Janus Henderson Global Life Sciences | 638.89K (1.46%) | 638.89K Increased by +100.00% | Sep 30, 23 |
| 13 | Janus Henderson Global Life Sciences D | 638.89K (1.46%) | 638.89K Increased by +100.00% | Sep 30, 23 |
| 14 | Fidelity Small Cap Index | 618.93K (1.41%) | 2.32K Increased by +0.38% | Oct 31, 24 |
| 15 | Candriam Global Equities Oncology | 612.16K (1.40%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 16 | iShares Russell 2000 Value ETF | 574.49K (1.31%) | -16.09K Decreased by -2.80% | Dec 31, 24 |
| 17 | Nuveen Quant Small Cap Equity R6 | 525.62K (1.20%) | 0.00 Increased by 0.00% | Nov 30, 24 |
| 18 | Direxion Daily S&P Biotech Bull 3X ETF | 501.66K (1.14%) | 3.54K Increased by +0.71% | Apr 30, 24 |
| 19 | T. Rowe Price Small-Cap Value | 497.43K (1.14%) | -1.00K Decreased by -0.20% | Sep 30, 23 |
| 20 | Janus Selection Global Life Science AUSD | 493.81K (1.13%) | 493.81K Increased by +100.00% | Sep 30, 23 |