| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Baker Bros Advisors LP | 11.05M (20.85%) | 1.00M Increased by +9.05% | Sep 30, 24 |
| 2 | T. Rowe Price Associates, Inc. | 9.88M (18.65%) | 643.19K Increased by +6.51% | Sep 30, 24 |
| 3 | State Street Corporation | 6.49M (12.25%) | 1.38M Increased by +21.20% | Mar 31, 24 |
| 4 | BlackRock Inc | 5.47M (10.33%) | 757.77K Increased by +13.85% | Sep 30, 24 |
| 5 | FCPM III SERVICES BV | 4.87M (9.19%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 6 | Redmile Group, LLC | 4.78M (9.03%) | -780.91K Decreased by -16.33% | Sep 30, 24 |
| 7 | Vanguard Group Inc | 3.47M (6.54%) | 571.13K Increased by +16.48% | Sep 30, 24 |
| 8 | BRAIDWELL LP | 3.07M (5.80%) | 2.06M Increased by +67.00% | Sep 30, 24 |
| 9 | Omega Fund Management LLC | 2.46M (4.65%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 10 | State Street Corp | 2.34M (4.42%) | 1.18M Increased by +50.52% | Sep 30, 24 |
| 11 | HHG PLC | 2.17M (4.09%) | 2.15M Increased by +99.17% | Sep 30, 23 |
| 12 | Bvf Inc | 2.14M (4.05%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 13 | Morgan Stanley - Brokerage Accounts | 1.69M (3.19%) | -1.78M Decreased by -105.43% | Sep 30, 24 |
| 14 | Boxer Capital LLC | 1.54M (2.90%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 15 | Geode Capital Management, LLC | 1.43M (2.70%) | 217.31K Increased by +15.21% | Sep 30, 24 |
| 16 | Camber Capital Management LLC | 1.35M (2.55%) | -1.40M Decreased by -103.70% | Jun 30, 24 |
| 17 | Loomis, Sayles & Company LP | 1.29M (2.44%) | 103.22K Increased by +8.00% | Sep 30, 23 |
| 18 | TANG CAPITAL MANAGEMENT LLC | 1.20M (2.27%) | 394.56K Increased by +32.88% | Sep 30, 24 |
| 19 | Citadel Advisors Llc | 1.20M (2.26%) | 60.92K Increased by +5.09% | Sep 30, 23 |
| 20 | Millennium Management LLC | 1.15M (2.18%) | -1.96M Decreased by -170.00% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | T. Rowe Price New Horizons | 4.73M (8.93%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | US Small-Cap Growth II Equity Comp | 4.73M (8.93%) | 337.32K Increased by +7.13% | Dec 31, 24 |
| 3 | T. Rowe Price Integrated US SmCapGrEq | 2.96M (5.60%) | 1.63M Increased by +54.85% | Dec 31, 24 |
| 4 | Vanguard Total Stock Mkt Idx Inv | 1.99M (3.75%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 5 | T. Rowe Price Health Sciences | 1.72M (3.24%) | -4.53K Decreased by -0.26% | Dec 31, 24 |
| 6 | iShares Russell 2000 ETF | 1.65M (3.12%) | -12.55K Decreased by -0.76% | Jan 31, 25 |
| 7 | T. Rowe Price Integrated US Sm Gr Eq | 1.48M (2.80%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 8 | T. Rowe Price New Horizons Tr-Z | 1.28M (2.41%) | 274.81K Increased by +21.52% | Dec 31, 24 |
| 9 | Vanguard Institutional Extnd Mkt Idx Tr | 888.12K (1.68%) | 22.41K Increased by +2.52% | Dec 31, 24 |
| 10 | SPDR® S&P Biotech ETF | 833.78K (1.57%) | -8.11K Decreased by -0.97% | Jan 31, 25 |
| 11 | Fidelity® Select Biotechnology | 825.12K (1.56%) | -31.60K Decreased by -3.83% | Nov 30, 23 |
| 12 | Janus Henderson Global Life Sciences | 638.89K (1.21%) | 638.89K Increased by +100.00% | Sep 30, 23 |
| 13 | Janus Henderson Global Life Sciences D | 638.89K (1.21%) | 638.89K Increased by +100.00% | Sep 30, 23 |
| 14 | Fidelity Small Cap Index | 617.93K (1.17%) | -997.00 Decreased by -0.16% | Nov 30, 24 |
| 15 | Candriam Global Equities Oncology | 612.16K (1.16%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 16 | iShares Russell 2000 Value ETF | 562.62K (1.06%) | 766.00 Increased by +0.14% | Jan 31, 25 |
| 17 | Nuveen Quant Small Cap Equity R6 | 525.62K (0.99%) | 0.00 Increased by 0.00% | Nov 30, 24 |
| 18 | Direxion Daily S&P Biotech Bull 3X ETF | 501.66K (0.95%) | 3.54K Increased by +0.71% | Apr 30, 24 |
| 19 | T. Rowe Price Small-Cap Value | 497.43K (0.94%) | -1.00K Decreased by -0.20% | Sep 30, 23 |
| 20 | Janus Selection Global Life Science AUSD | 493.81K (0.93%) | 493.81K Increased by +100.00% | Sep 30, 23 |