| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RTW INVESTMENTS, LLC | 5.16M (13.93%) | 892.80K Increased by +17.31% | Jun 30, 25 |
| 2 | EcoR1 Capital, LLC | 3.99M (10.77%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 3 | Vestal Point Capital LP | 3.70M (9.99%) | -1.09M Decreased by -29.53% | Jun 30, 25 |
| 4 | venBio Select Advisor LLC | 3.63M (9.79%) | 1.45M Increased by +40.00% | Jun 30, 25 |
| 5 | State Street Corporation | 3.48M (9.39%) | 28.59K Increased by +0.82% | Dec 31, 23 |
| 6 | Aberdeen Group PLC | 2.75M (7.43%) | 535.16K Increased by +19.46% | Jun 30, 25 |
| 7 | Boxer Capital LLC | 2.23M (6.01%) | 2.23M Increased by +100.00% | Sep 30, 24 |
| 8 | Millennium Management LLC | 2.19M (5.91%) | 1.67M Increased by +76.47% | Sep 30, 24 |
| 9 | Jefferies Financial Group Inc | 2.10M (5.66%) | 2.10M Increased by +100.00% | Jun 30, 25 |
| 10 | Nantahala Capital Management, LLC | 2.05M (5.54%) | -704.11K Decreased by -34.32% | Jun 30, 25 |
| 11 | JPMorgan Chase & Co | 1.81M (4.88%) | 1.49M Increased by +82.51% | Jun 30, 25 |
| 12 | Point72 Asset Management, L.P. | 1.77M (4.78%) | 794.46K Increased by +44.85% | Dec 31, 24 |
| 13 | Franklin Resources Inc | 1.61M (4.33%) | -382.17K Decreased by -23.80% | Jun 30, 25 |
| 14 | Sofinnova Ventures | 1.56M (4.21%) | 1.01M Increased by +64.98% | Jun 30, 25 |
| 15 | abrdn PLC | 1.51M (4.07%) | -419.73K Decreased by -27.81% | Dec 31, 24 |
| 16 | Goldman Sachs Group Inc | 1.39M (3.75%) | 928.87K Increased by +66.79% | Dec 31, 23 |
| 17 | Integral Health Asset Management, LLC | 1.35M (3.64%) | 100.00K Increased by +7.41% | Jun 30, 25 |
| 18 | Orbimed Advisors, LLC | 1.35M (3.64%) | -716.55K Decreased by -53.16% | Dec 31, 23 |
| 19 | BlackRock Inc | 1.33M (3.60%) | -103.32K Decreased by -7.75% | Jun 30, 25 |
| 20 | Pictet Asset Manangement SA | 1.32M (3.57%) | 320.55K Increased by +24.21% | Dec 31, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | abrdn Healthcare Investors | 1.53M (4.13%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 2 | Franklin Biotechnology Discv A(acc)USD | 1.04M (2.80%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 3 | JPMorgan Small Cap Growth A | 882.46K (2.38%) | -9.50K Decreased by -1.08% | Jul 31, 25 |
| 4 | SPDR® S&P Biotech ETF | 838.29K (2.26%) | 1.87K Increased by +0.22% | Aug 31, 25 |
| 5 | abrdn World Healthcare | 736.66K (1.99%) | 97.58K Increased by +13.25% | Jul 31, 25 |
| 6 | Delaware Healthcare I | 706.17K (1.91%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 7 | Macquarie Healthcare I | 706.17K (1.91%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 8 | abrdn Life Sciences Investors | 704.74K (1.90%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 9 | Biotech Growth Ord | 618.55K (1.67%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 10 | Franklin Biotechnology Discovery A | 568.80K (1.54%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 11 | MEDICAL BioHealth EUR Acc | 554.36K (1.50%) | 119.24K Increased by +21.51% | Jun 30, 25 |
| 12 | Vanguard Institutional Extnd Mkt Idx Tr | 550.98K (1.49%) | -241.47K Decreased by -43.83% | Jul 31, 25 |
| 13 | Pictet Biopharmaceutical Mother | 499.20K (1.35%) | 179.52K Increased by +35.96% | Oct 13, 23 |
| 14 | AlphaCentric Life Sciences & Hlthcare I | 460.00K (1.24%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 15 | AlphaCentric LifeSci Healthcare I | 460.00K (1.24%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 16 | Xtrackers S&P Global Infra Swap ETF 1C | 420.69K (1.14%) | 0.00 Increased by 0.00% | Oct 31, 24 |
| 17 | Fidelity Select Biotechnology | 414.98K (1.12%) | -6.30K Decreased by -1.52% | Jul 31, 25 |
| 18 | International Biotechnology Ord | 408.42K (1.10%) | -284.87K Decreased by -69.75% | Jul 31, 25 |
| 19 | Columbia Small Cap Value Discv A | 391.19K (1.06%) | 10.70K Increased by +2.74% | Jul 31, 25 |
| 20 | Columbia Small Cap Value I A | 391.19K (1.06%) | 10.70K Increased by +2.74% | Jul 31, 25 |