| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Orbimed Advisors, LLC | 2.25M (89.92%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 2 | Atlas Venture Life Science Advisors, LLC | 2.09M (83.50%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 3 | Opaleye Management Inc | 1.26M (50.14%) | 1.04M Increased by +83.02% | Mar 31, 26 |
| 4 | The Carlyle Group Inc | 1.10M (44.01%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 5 | Vanguard Group Inc | 321.05K (12.81%) | 25.64K Increased by +7.99% | Dec 31, 25 |
| 6 | ARCH VENTURE CORP | 320.48K (12.79%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 7 | Vanguard Capital Management, LLC | 306.40K (12.23%) | 306.40K Increased by +100.00% | Mar 31, 26 |
| 8 | Mackenzie Investments | 246.30K (9.83%) | 246.30K Increased by +100.00% | Mar 31, 26 |
| 9 | Sanofi | 244.08K (9.74%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 10 | Renaissance Technologies Corp | 206.91K (8.26%) | 107.31K Increased by +51.86% | Mar 31, 26 |
| 11 | Acadian Asset Management LLC | 172.59K (6.89%) | 172.13K Increased by +99.74% | Mar 31, 26 |
| 12 | MONIMUS CAPITAL MANAGEMENT, LP | 134.31K (5.36%) | 134.31K Increased by +100.00% | Mar 31, 26 |
| 13 | Geode Capital Management, LLC | 118.15K (4.72%) | 12.04K Increased by +10.19% | Mar 31, 26 |
| 14 | Pfizer Inc | 101.62K (4.06%) | -176.16K Decreased by -173.35% | Mar 31, 26 |
| 15 | BlackRock Inc | 86.15K (3.44%) | 26.21K Increased by +30.43% | Mar 31, 26 |
| 16 | Jane Street Group LLC | 65.60K (2.62%) | 40.23K Increased by +61.32% | Mar 31, 26 |
| 17 | Marshall Wace Asset Management Ltd | 52.44K (2.09%) | 52.44K Increased by +100.00% | Mar 31, 26 |
| 18 | Vanguard Fiduciary Trust Co | 49.99K (2.00%) | 49.99K Increased by +100.00% | Mar 31, 26 |
| 19 | Citadel Advisors Llc | 45.73K (1.83%) | 35.61K Increased by +77.88% | Dec 31, 25 |
| 20 | Two Sigma Investments LLC | 42.35K (1.69%) | -4.48K Decreased by -10.58% | Mar 31, 26 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 186.72K (7.45%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 2 | Avantis US Small Cap Value ETF | 128.51K (5.13%) | 704.00 Increased by +0.55% | May 30, 26 |
| 3 | Vanguard Institutional Extnd Mkt Idx Tr | 119.69K (4.78%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 4 | Mackenzie GQE US Small Cap F8 | 73.08K (2.92%) | 73.08K Increased by +100.00% | Mar 31, 26 |
| 5 | Blackrock Extended Mkt Fund CF | 38.40K (1.53%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 6 | BlackRock Extended Equity Market Fund K | 32.69K (1.30%) | 22.25K Increased by +68.04% | Mar 31, 26 |
| 7 | Fidelity Extended Market Index | 30.02K (1.20%) | -26.80K Decreased by -89.29% | Apr 30, 26 |
| 8 | Fidelity Total Market Index | 16.80K (0.67%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 9 | Fidelity Series Total Market Index | 15.34K (0.61%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 10 | Spartan Extended Market Index Pool F | 14.77K (0.59%) | 110.00 Increased by +0.74% | Apr 30, 26 |
| 11 | Dimensional US Small Cap ETF | 14.65K (0.58%) | 0.00 Increased by 0.00% | May 29, 26 |
| 12 | NT Ext Equity Mkt Index Fund - Lending | 13.02K (0.52%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 13 | Northern Trust Extended Eq Market Idx | 13.02K (0.52%) | 7.41K Increased by +56.92% | Mar 31, 26 |
| 14 | Bridgeway Ultra-Small Company | 12.61K (0.50%) | 12.61K Increased by +100.00% | Mar 31, 26 |
| 15 | Extended Equity Market Fund B | 12.18K (0.49%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 16 | Extended Equity Market Fund E | 12.18K (0.49%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 17 | NT Ext Equity Mkt Index Fund - NL | 11.72K (0.47%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 18 | NT Ext Equity Mkt Idx Fd - DC - NL - T2 | 9.18K (0.37%) | -48.00 Decreased by -0.52% | Mar 31, 26 |
| 19 | Fidelity Nasdaq Composite Index | 8.32K (0.33%) | 1.83K Increased by +21.96% | Apr 30, 26 |
| 20 | Spartan Total Market Index Pool G | 7.96K (0.32%) | 0.00 Increased by 0.00% | Apr 30, 26 |