| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Frazier Life Sciences Management, L.P. | 12.47M (20.66%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 2 | Medicxi Ventures Management (Jersey) Ltd | 7.46M (12.37%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 3 | Jennison Associates LLC | 7.04M (11.67%) | -20.18K Decreased by -0.29% | Mar 31, 25 |
| 4 | Amvescap Plc. | 4.32M (7.16%) | 401.61K Increased by +9.29% | Mar 31, 26 |
| 5 | BlackRock Inc | 4.06M (6.73%) | 506.45K Increased by +12.47% | Mar 31, 26 |
| 6 | Millennium Management LLC | 4.02M (6.67%) | 1.94M Increased by +48.24% | Mar 31, 26 |
| 7 | The Carlyle Group Inc | 3.50M (5.80%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 8 | Vanguard Group Inc | 3.18M (5.27%) | -38.36K Decreased by -1.21% | Dec 31, 25 |
| 9 | Vanguard Capital Management, LLC | 2.58M (4.28%) | 2.58M Increased by +100.00% | Mar 31, 26 |
| 10 | Checkpoint Capital LP | 2.27M (3.77%) | 769.85K Increased by +33.85% | Dec 31, 24 |
| 11 | NEA Management Company, LLC | 1.96M (3.25%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 12 | 683 Capital Management LLC | 1.85M (3.07%) | 65.00K Increased by +3.51% | Mar 31, 26 |
| 13 | Portolan Capital Management, LLC | 1.70M (2.82%) | 569.83K Increased by +33.52% | Sep 30, 24 |
| 14 | Ensign Peak Advisors Inc | 1.63M (2.70%) | -724.21K Decreased by -44.49% | Mar 31, 26 |
| 15 | Gilder Gagnon Howe & CO LLC | 1.62M (2.69%) | 150.62K Increased by +9.28% | Sep 30, 24 |
| 16 | Catalys Pacific LLC | 1.49M (2.48%) | 64.84K Increased by +4.34% | Mar 31, 26 |
| 17 | Orbimed Advisors, LLC | 1.45M (2.40%) | 1.45M Increased by +100.00% | Sep 30, 24 |
| 18 | GW&K Investment Management, LLC | 1.42M (2.36%) | 114.43K Increased by +8.05% | Mar 31, 26 |
| 19 | Federated Hermes Inc | 1.40M (2.33%) | 1.40M Increased by +100.00% | Sep 30, 24 |
| 20 | State Street Corp | 1.39M (2.30%) | 237.35K Increased by +17.11% | Mar 31, 26 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Invesco Global A | 2.34M (3.88%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 2 | Invesco OFI Global Equity | 2.34M (3.88%) | 367.07K Increased by +15.67% | Mar 31, 26 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 1.96M (3.25%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 4 | Jennison Health Sciences Equity | 1.78M (2.95%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 5 | Vanguard US Total Market Shares ETF | 1.65M (2.73%) | 280.90K Increased by +17.06% | Sep 30, 24 |
| 6 | Jennison SMid Cap Core Equity | 1.58M (2.62%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 7 | Strategic Advisers U.S. Total Stock{mg} | 1.48M (2.45%) | -273.72K Decreased by -18.55% | Sep 30, 24 |
| 8 | Strategic Advisers Small-Mid Cap | 1.24M (2.06%) | 278.88K Increased by +22.43% | Jul 31, 24 |
| 9 | PGIM Jennison Small Company A | 1.21M (2.00%) | -373.30K Decreased by -30.96% | Apr 30, 25 |
| 10 | iShares Russell 2000 ETF | 1.11M (1.84%) | 10.24K Increased by +0.92% | May 29, 26 |
| 11 | Strategic Advisers U.S. Total Stock | 967.60K (1.60%) | -300.00 Decreased by -0.03% | Apr 30, 26 |
| 12 | AZ InvestEd Ivy Small Cap Growth E | 892.79K (1.48%) | 73.47K Increased by +8.23% | Apr 30, 26 |
| 13 | PGIM Jennison Health Sciences Z | 867.63K (1.44%) | -913.72K Decreased by -105.31% | Apr 30, 25 |
| 14 | Biotech Growth Ord | 847.90K (1.41%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 15 | Franklin Biotechnology Discv A(acc)USD | 840.26K (1.39%) | 209.84K Increased by +24.97% | Apr 30, 26 |
| 16 | Wasatch Micro Cap | 806.56K (1.34%) | 57.42K Increased by +7.12% | Mar 31, 26 |
| 17 | Federated Hermes Kaufmann Growth | 690.00K (1.14%) | 690.00K Increased by +100.00% | Sep 30, 24 |
| 18 | Federated Hermes Kaufmann R | 690.00K (1.14%) | 690.00K Increased by +100.00% | Sep 30, 24 |
| 19 | Franklin Small Cap Growth Adv | 565.90K (0.94%) | 565.90K Increased by +100.00% | Apr 30, 26 |
| 20 | Vanguard Institutional Extnd Mkt Idx Tr | 562.11K (0.93%) | 2.91K Increased by +0.52% | Apr 30, 26 |