| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Medicxi Ventures Management (Jersey) Ltd | 7.46M (14.47%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 2 | Jennison Associates LLC | 7.04M (13.65%) | -20.18K Decreased by -0.29% | Mar 31, 25 |
| 3 | Amvescap Plc. | 3.65M (7.08%) | -20.57K Decreased by -0.56% | Mar 31, 25 |
| 4 | The Carlyle Group Inc | 3.50M (6.78%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 5 | BlackRock Inc | 3.32M (6.44%) | -178.77K Decreased by -5.38% | Mar 31, 25 |
| 6 | Vanguard Group Inc | 2.79M (5.40%) | 8.62K Increased by +0.31% | Jun 30, 25 |
| 7 | Ensign Peak Advisors Inc | 2.52M (4.88%) | 5.69K Increased by +0.23% | Jun 30, 25 |
| 8 | Checkpoint Capital LP | 2.27M (4.41%) | 769.85K Increased by +33.85% | Dec 31, 24 |
| 9 | NEA Management Company, LLC | 1.96M (3.80%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 10 | Wasatch Advisors LP | 1.70M (3.30%) | 142.70K Increased by +8.39% | Mar 31, 25 |
| 11 | Portolan Capital Management, LLC | 1.70M (3.29%) | 569.83K Increased by +33.52% | Sep 30, 24 |
| 12 | Gilder Gagnon Howe & CO LLC | 1.62M (3.15%) | 150.62K Increased by +9.28% | Sep 30, 24 |
| 13 | Orbimed Advisors, LLC | 1.45M (2.81%) | 1.45M Increased by +100.00% | Sep 30, 24 |
| 14 | 683 Capital Management LLC | 1.45M (2.80%) | 420.00K Increased by +29.07% | Mar 31, 25 |
| 15 | Federated Hermes Inc | 1.40M (2.72%) | 1.40M Increased by +100.00% | Sep 30, 24 |
| 16 | Decheng Capital LLC | 1.25M (2.42%) | 400.00K Increased by +32.00% | Sep 30, 24 |
| 17 | TANG CAPITAL MANAGEMENT LLC | 1.20M (2.33%) | 700.00K Increased by +58.33% | Mar 31, 25 |
| 18 | Catalys Pacific LLC | 1.17M (2.26%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 19 | Propel Bio Management LLC | 1.13M (2.20%) | 145.00K Increased by +12.78% | Mar 31, 25 |
| 20 | Morgan Stanley - Brokerage Accounts | 1.13M (2.19%) | 164.63K Increased by +14.56% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Invesco Global A | 1.98M (3.83%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 2 | Invesco OFI Global Equity | 1.98M (3.83%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 3 | Jennison Health Sciences Equity | 1.78M (3.45%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 4 | Vanguard US Total Market Shares ETF | 1.65M (3.19%) | 280.90K Increased by +17.06% | Sep 30, 24 |
| 5 | Jennison SMid Cap Core Equity | 1.58M (3.06%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 6 | Vanguard Total Stock Mkt Idx Inv | 1.55M (3.01%) | -34.49K Decreased by -2.22% | Jul 31, 25 |
| 7 | Strategic Advisers U.S. Total Stock{mg} | 1.48M (2.86%) | -273.72K Decreased by -18.55% | Sep 30, 24 |
| 8 | Strategic Advisers Small-Mid Cap | 1.24M (2.41%) | 278.88K Increased by +22.43% | Jul 31, 24 |
| 9 | PGIM Jennison Small Company A | 1.21M (2.34%) | -373.30K Decreased by -30.96% | Apr 30, 25 |
| 10 | Wasatch Ultra Growth | 1.01M (1.96%) | -458.57K Decreased by -45.37% | Jun 30, 25 |
| 11 | iShares Russell 2000 ETF | 981.31K (1.90%) | -18.69K Decreased by -1.90% | Jul 31, 25 |
| 12 | PGIM Jennison Health Sciences Z | 867.63K (1.68%) | -913.72K Decreased by -105.31% | Apr 30, 25 |
| 13 | Biotech Growth Ord | 847.90K (1.64%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 14 | Federated Hermes Kaufmann Growth | 690.00K (1.34%) | 690.00K Increased by +100.00% | Sep 30, 24 |
| 15 | Federated Hermes Kaufmann R | 690.00K (1.34%) | 690.00K Increased by +100.00% | Sep 30, 24 |
| 16 | Strategic Advisers U.S. Total Stock | 632.61K (1.23%) | 0.00 Increased by 0.00% | May 31, 25 |
| 17 | Federated Hermes Kaufmann Small Cap A | 550.00K (1.07%) | 550.00K Increased by +100.00% | Sep 30, 24 |
| 18 | Federated Hermes Kaufmann Small Cap Grow | 550.00K (1.07%) | 550.00K Increased by +100.00% | Sep 30, 24 |
| 19 | Vanguard Institutional Extnd Mkt Idx Tr | 496.32K (0.96%) | -217.10K Decreased by -43.74% | Jul 31, 25 |
| 20 | JENNISON SMALL/MID CAP EQUITY 3 | 469.76K (0.91%) | 15.77K Increased by +3.36% | Mar 31, 25 |