| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RA Capital Management, LLC | 10.81M (17.87%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 2 | COMMODORE CAPITAL LP | 4.66M (7.71%) | 511.04K Increased by +10.96% | Sep 30, 24 |
| 3 | BlackRock Inc | 4.12M (6.81%) | 416.60K Increased by +10.12% | Dec 31, 25 |
| 4 | Boxer Capital LLC | 4.03M (6.67%) | -1.58M Decreased by -39.15% | Sep 30, 24 |
| 5 | Adage Capital Partners Gp LLC | 3.60M (5.96%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 6 | NEA Management Company, LLC | 3.57M (5.90%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 7 | Samsara BioCapital, LLC | 3.51M (5.80%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 8 | SR ONE CAPITAL MANAGEMENT, LP | 3.33M (5.51%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 9 | GSK PLC | 3.15M (5.21%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 10 | Vanguard Group Inc | 2.60M (4.30%) | 105.65K Increased by +4.07% | Dec 31, 25 |
| 11 | Monaco Asset Management | 2.52M (4.17%) | -25.00K Decreased by -0.99% | Mar 31, 26 |
| 12 | Jefferies Financial Group Inc | 2.50M (4.14%) | 2.25M Increased by +90.02% | Dec 31, 24 |
| 13 | Deerfield Management Co | 2.15M (3.57%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 14 | Wasatch Advisors Inc. | 2.10M (3.47%) | 251.79K Increased by +11.99% | Dec 31, 23 |
| 15 | Alyeska Investment Group, L.P. | 2.08M (3.45%) | 144.00 Increased by +0.01% | Dec 31, 25 |
| 16 | EcoR1 Capital, LLC | 2.00M (3.31%) | 2.00M Increased by +100.00% | Mar 31, 24 |
| 17 | Morgan Stanley - Brokerage Accounts | 1.75M (2.90%) | 1.38M Increased by +78.66% | Dec 31, 24 |
| 18 | Renaissance Technologies Corp | 1.73M (2.87%) | 30.35K Increased by +1.75% | Mar 31, 26 |
| 19 | Wasatch Advisors LP | 1.58M (2.61%) | 1.56K Increased by +0.10% | Mar 31, 26 |
| 20 | TANG CAPITAL MANAGEMENT LLC | 1.48M (2.45%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard US Total Market Shares ETF | 1.82M (3.01%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 2 | Wasatch Ultra Growth | 1.49M (2.46%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 1.42M (2.34%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 4 | iShares Russell 2000 ETF | 1.15M (1.91%) | 64.32K Increased by +5.57% | Apr 30, 26 |
| 5 | T. Rowe Price Small-Cap Stock | 956.65K (1.58%) | -1.40K Decreased by -0.15% | Sep 30, 23 |
| 6 | T. Rowe Price US Small-Cap Core Equity | 956.65K (1.58%) | -1.40K Decreased by -0.15% | Sep 30, 23 |
| 7 | Biotech Growth Ord | 821.40K (1.36%) | 0.00 Increased by 0.00% | May 31, 25 |
| 8 | CT (Lux) American Smaller Com 9U USD | 669.14K (1.11%) | 35.52K Increased by +5.31% | Oct 31, 24 |
| 9 | Wasatch Micro Cap | 668.36K (1.11%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 10 | CT American Smaller Coms(US) InstAccGBP | 615.86K (1.02%) | -11.25K Decreased by -1.83% | Oct 31, 24 |
| 11 | Vanguard Institutional Extnd Mkt Idx Tr | 557.53K (0.92%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 12 | JPM Thematics Genetic Thrps C2 dist USD | 555.19K (0.92%) | -26.81K Decreased by -4.83% | Mar 31, 26 |
| 13 | JPM Thmtcs Gentc Thrps C2 dist USD | 555.19K (0.92%) | -26.81K Decreased by -4.83% | Mar 31, 26 |
| 14 | T. Rowe Price Instl Small-Cap Stock | 536.71K (0.89%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 15 | T. Rowe Price Small-Cap Value | 511.45K (0.85%) | -15.76K Decreased by -3.08% | Sep 30, 24 |
| 16 | JPMorgan US Small Company L | 463.11K (0.77%) | -381.48K Decreased by -82.37% | Mar 31, 25 |
| 17 | T. Rowe Price US Smlr Cm Eq A USD | 441.17K (0.73%) | 59.24K Increased by +13.43% | Mar 31, 24 |
| 18 | T. Rowe Price U.S. SC Core Eq Tr-Z | 431.54K (0.71%) | 1.40K Increased by +0.32% | Sep 30, 23 |
| 19 | Fidelity Small Cap Index | 416.58K (0.69%) | -1.69K Decreased by -0.41% | Feb 28, 26 |
| 20 | Wasatch Small Cap Growth Investor | 415.44K (0.69%) | -1.28M Decreased by -307.18% | Sep 30, 23 |