| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RA Capital Management, LLC | 18.70M (152.85%) | 18.70M Increased by +100.00% | Sep 30, 23 |
| 2 | BlackRock Inc | 15.71M (128.39%) | -384.26K Decreased by -2.45% | Mar 31, 25 |
| 3 | Vanguard Group Inc | 12.31M (100.62%) | -18.33K Decreased by -0.15% | Mar 31, 25 |
| 4 | Samlyn Capital, LLC | 9.67M (79.02%) | 467.10K Increased by +4.83% | Dec 31, 24 |
| 5 | Nantahala Capital Management, LLC | 7.79M (63.67%) | -20.95K Decreased by -0.27% | Mar 31, 25 |
| 6 | Acadian Asset Management LLC | 7.30M (59.68%) | 7.23M Increased by +99.07% | Mar 31, 25 |
| 7 | Citadel Advisors Llc | 6.95M (56.85%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 8 | Eventide Asset Management, LLC | 6.65M (54.36%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 9 | PRIMECAP Management Company | 5.35M (43.77%) | -185.80K Decreased by -3.47% | Mar 31, 25 |
| 10 | Renaissance Technologies Corp | 4.70M (38.43%) | 791.00K Increased by +16.82% | Mar 31, 25 |
| 11 | Almitas Capital LLC | 4.61M (37.69%) | 3.69M Increased by +80.04% | Mar 31, 25 |
| 12 | Geode Capital Management, LLC | 4.01M (32.77%) | 51.54K Increased by +1.29% | Mar 31, 25 |
| 13 | TCG Crossover Management, LLC | 4.00M (32.70%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 14 | TANG CAPITAL MANAGEMENT LLC | 3.94M (32.20%) | 3.80M Increased by +96.46% | Sep 30, 23 |
| 15 | Woodline Partners LP | 3.69M (30.18%) | -1.28M Decreased by -34.74% | Mar 31, 25 |
| 16 | AQR Capital Management LLC | 3.64M (29.76%) | 2.81M Increased by +77.11% | Mar 31, 25 |
| 17 | Stonepine Capital Management Llc | 3.48M (28.45%) | 3.48M Increased by +100.00% | Mar 31, 24 |
| 18 | State Street Corp | 3.26M (26.63%) | -13.81K Decreased by -0.42% | Mar 31, 25 |
| 19 | Jacobs Levy Equity Management, Inc. | 3.01M (24.59%) | 380.97K Increased by +12.67% | Mar 31, 25 |
| 20 | Altium Capital Management, LP | 3.00M (24.52%) | 2.99M Increased by +99.62% | Dec 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Eventide Healthcare & Life Sciences I | 6.65M (54.36%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 5.72M (46.79%) | 0.00 Increased by 0.00% | May 31, 25 |
| 3 | Vanguard US Total Market Shares ETF | 5.72M (46.79%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 4 | iShares Russell 2000 ETF | 4.62M (37.76%) | 0.00 Increased by 0.00% | May 31, 25 |
| 5 | PRIMECAP Odyssey Aggressive Growth | 3.46M (28.32%) | -72.30K Decreased by -2.09% | Mar 31, 25 |
| 6 | Vanguard Institutional Extnd Mkt Idx Tr | 2.66M (21.76%) | 0.00 Increased by 0.00% | May 31, 25 |
| 7 | Pictet Biopharmaceutical Mother | 1.85M (15.09%) | 999.77K Increased by +54.15% | Apr 13, 23 |
| 8 | Fidelity Small Cap Index | 1.78M (14.54%) | -11.15K Decreased by -0.63% | Mar 31, 25 |
| 9 | iShares Russell 2000 Value ETF | 1.66M (13.60%) | 0.00 Increased by 0.00% | May 31, 25 |
| 10 | Vanguard Strategic Equity Inv | 1.52M (12.40%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 11 | PRIMECAP Odyssey Growth | 1.37M (11.17%) | -78.90K Decreased by -5.78% | Mar 31, 25 |
| 12 | BlackRock Advantage Small Cap Core Instl | 1.01M (8.24%) | 0.00 Increased by 0.00% | May 31, 25 |
| 13 | Bridgeway Ultra-Small Company | 992.10K (8.11%) | -300.00K Decreased by -30.24% | Mar 31, 25 |
| 14 | Fidelity® Extended Market Index | 921.63K (7.53%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 15 | State St Russell Sm/Mid Cp® Indx NL Cl C | 913.93K (7.47%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 16 | State St Russell Sm/Mid Cp® Indx SL Cl I | 913.93K (7.47%) | 0.00 Increased by 0.00% | May 31, 25 |
| 17 | Fidelity Extended Market Index | 898.55K (7.34%) | -8.59K Decreased by -0.96% | Apr 30, 25 |
| 18 | Vanguard Russell 2000 ETF | 892.48K (7.30%) | 8.00K Increased by +0.90% | May 31, 25 |
| 19 | Schwab US Small-Cap ETF™ | 766.70K (6.27%) | -2.07K Decreased by -0.27% | May 31, 25 |
| 20 | Vanguard Strategic Small-Cap Equity Inv | 763.31K (6.24%) | 0.00 Increased by 0.00% | Mar 31, 25 |