| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Frazier Life Sciences Management, L.P. | 16.94M (23.71%) | 241.82K Increased by +1.43% | Dec 31, 25 |
| 2 | Capital World Investors | 9.82M (13.74%) | 1.43M Increased by +14.61% | Sep 30, 25 |
| 3 | RA Capital Management, LLC | 9.55M (13.36%) | -588.75K Decreased by -6.16% | Dec 31, 25 |
| 4 | FCPM III SERVICES BV | 9.21M (12.89%) | -1.42M Decreased by -15.41% | Sep 30, 25 |
| 5 | Bain Capital Life Sciences Investors, LLC | 7.31M (10.22%) | -3.41M Decreased by -46.71% | Dec 31, 25 |
| 6 | FMR Inc | 6.41M (8.97%) | 877.69K Increased by +13.69% | Dec 31, 25 |
| 7 | Wellington Management Company LLP | 5.03M (7.04%) | 1.01M Increased by +20.13% | Dec 31, 25 |
| 8 | Viking Global Investors LP | 4.20M (5.88%) | -2.27M Decreased by -54.05% | Dec 31, 25 |
| 9 | Deerfield Management Co | 4.16M (5.83%) | -101.90K Decreased by -2.45% | Dec 31, 25 |
| 10 | Jennison Associates LLC | 3.49M (4.88%) | -709.33K Decreased by -20.33% | Dec 31, 25 |
| 11 | Duquesne Family Office LLC | 3.07M (4.30%) | 1.15M Increased by +37.34% | Dec 31, 25 |
| 12 | Adage Capital Partners Gp LLC | 3.01M (4.22%) | 1.06M Increased by +35.26% | Jun 30, 25 |
| 13 | Polar Capital Holdings PLC | 2.91M (4.07%) | 393.86K Increased by +13.53% | Sep 30, 25 |
| 14 | Medicxi Ventures Management (Jersey) Ltd | 2.87M (4.02%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 15 | Goldman Sachs Group Inc | 2.77M (3.87%) | 2.77M Increased by +100.00% | Dec 31, 23 |
| 16 | JPMorgan Chase & Co | 2.60M (3.65%) | 1.15M Increased by +44.00% | Sep 30, 25 |
| 17 | Cormorant Asset Management, LLC | 2.17M (3.04%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 18 | AllianceBernstein L.P. | 2.14M (3.00%) | -189.81K Decreased by -8.86% | Sep 30, 25 |
| 19 | HHG PLC | 2.12M (2.96%) | 155.01K Increased by +7.32% | Sep 30, 25 |
| 20 | Capital Research & Mgmt Co - Division 3 | 2.06M (2.89%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | American Funds SMALLCAP World A | 8.60M (12.03%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 2 | Vanguard Health Care Inv | 3.67M (5.14%) | 823.72K Increased by +22.43% | Dec 31, 25 |
| 3 | Capital Group Global Equity Canada F | 2.52M (3.53%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 4 | Polar Capital Biotech S Inc | 2.50M (3.50%) | 2.50M Increased by +100.00% | Jan 31, 26 |
| 5 | Fidelity Contrafund | 1.19M (1.67%) | 205.55K Increased by +17.25% | Jan 31, 26 |
| 6 | Jennison SMid Cap Core Equity | 966.54K (1.35%) | -119.37K Decreased by -12.35% | Dec 31, 25 |
| 7 | PGIM Jennison Small Company A | 966.54K (1.35%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 8 | AB Small Cap Growth A | 686.06K (0.96%) | 32.56K Increased by +4.75% | Jul 31, 25 |
| 9 | Candriam Eqs L Biotech C USD Cap | 684.30K (0.96%) | 13.07K Increased by +1.91% | Oct 31, 25 |
| 10 | Pictet-Global Megatrend Sel I USD | 682.29K (0.95%) | 10.43K Increased by +1.53% | May 31, 25 |
| 11 | American Funds New Economy A | 671.10K (0.94%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 12 | Capital Group New Economy Comp | 671.10K (0.94%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 13 | Fidelity Select Health Care | 670.00K (0.94%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 14 | Fidelity Advisor Biotechnology I | 586.40K (0.82%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 15 | iShares Biotechnology ETF | 564.71K (0.79%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 16 | Fidelity Select Biotechnology | 562.50K (0.79%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 17 | AB Discovery Growth A | 535.54K (0.75%) | 41.26K Increased by +7.70% | Jul 31, 25 |
| 18 | Jennison Health Sciences Equity | 534.10K (0.75%) | -243.18K Decreased by -45.53% | Dec 31, 25 |
| 19 | PGIM Jennison Health Sciences Z | 534.10K (0.75%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 20 | BNP Paribas Health Cr Innovtr Cl Cap | 514.18K (0.72%) | 514.18K Increased by +100.00% | Jan 31, 26 |