| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Frazier Life Sciences Management, L.P. | 16.94M (21.00%) | 241.82K Increased by +1.43% | Dec 31, 25 |
| 2 | Capital World Investors | 11.11M (13.77%) | 1.13M Increased by +10.13% | Mar 31, 26 |
| 3 | RA Capital Management, LLC | 9.55M (11.83%) | -588.75K Decreased by -6.16% | Dec 31, 25 |
| 4 | FCPM III SERVICES BV | 9.20M (11.40%) | -13.48K Decreased by -0.15% | Dec 31, 25 |
| 5 | Bain Capital Life Sciences Investors, LLC | 7.31M (9.05%) | -3.41M Decreased by -46.71% | Dec 31, 25 |
| 6 | FMR Inc | 6.41M (7.95%) | 877.69K Increased by +13.69% | Dec 31, 25 |
| 7 | Wellington Management Company LLP | 5.03M (6.24%) | 1.01M Increased by +20.13% | Dec 31, 25 |
| 8 | Viking Global Investors LP | 4.20M (5.21%) | -2.27M Decreased by -54.05% | Dec 31, 25 |
| 9 | Deerfield Management Co | 4.16M (5.16%) | -101.90K Decreased by -2.45% | Dec 31, 25 |
| 10 | Duquesne Family Office LLC | 3.07M (3.80%) | 1.15M Increased by +37.34% | Dec 31, 25 |
| 11 | Polar Capital Holdings PLC | 2.78M (3.44%) | -135.41K Decreased by -4.88% | Dec 31, 25 |
| 12 | Goldman Sachs Group Inc | 2.77M (3.43%) | 2.77M Increased by +100.00% | Dec 31, 23 |
| 13 | Jennison Associates LLC | 2.75M (3.41%) | -738.82K Decreased by -26.86% | Mar 31, 26 |
| 14 | Medicxi Ventures Management (Jersey) Ltd | 2.67M (3.31%) | -195.38K Decreased by -7.31% | Mar 31, 26 |
| 15 | JPMorgan Chase & Co | 2.60M (3.23%) | 1.15M Increased by +44.00% | Sep 30, 25 |
| 16 | HHG PLC | 2.34M (2.90%) | 224.65K Increased by +9.59% | Dec 31, 25 |
| 17 | Westfield Capital Management Company, L.P. | 2.20M (2.73%) | 2.20M Increased by +100.00% | Mar 31, 26 |
| 18 | Cormorant Asset Management, LLC | 2.17M (2.70%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 19 | Woodline Partners LP | 1.90M (2.35%) | -545.20K Decreased by -28.74% | Jun 30, 25 |
| 20 | Maverick Capital Ltd | 1.89M (2.35%) | 389.48K Increased by +20.56% | Dec 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | American Funds SMALLCAP World A | 8.40M (10.40%) | -200.00K Decreased by -2.38% | Mar 31, 26 |
| 2 | Vanguard Health Care Inv | 3.95M (4.90%) | 280.70K Increased by +7.10% | Mar 31, 26 |
| 3 | Polar Capital Biotech S Inc | 2.68M (3.32%) | 177.97K Increased by +6.65% | Mar 31, 26 |
| 4 | Capital Group Global Equity Canada F | 2.52M (3.12%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 5 | Strategic Advisers Fidelity US TtlStk | 1.78M (2.20%) | 316.00K Increased by +17.76% | Mar 31, 26 |
| 6 | Fidelity Contrafund | 1.27M (1.57%) | 77.77K Increased by +6.13% | Mar 31, 26 |
| 7 | Jennison SMid Cap Core Equity | 966.54K (1.20%) | -119.37K Decreased by -12.35% | Dec 31, 25 |
| 8 | American Funds New Economy A | 957.48K (1.19%) | 286.38K Increased by +29.91% | Mar 31, 26 |
| 9 | Capital Group New Economy Comp | 957.48K (1.19%) | 286.38K Increased by +29.91% | Mar 31, 26 |
| 10 | AB Small Cap Growth A | 686.06K (0.85%) | 32.56K Increased by +4.75% | Jul 31, 25 |
| 11 | Candriam Eqs L Biotech C USD Cap | 684.30K (0.85%) | 13.07K Increased by +1.91% | Oct 31, 25 |
| 12 | Pictet-Global Megatrend Sel I USD | 682.29K (0.85%) | 10.43K Increased by +1.53% | May 31, 25 |
| 13 | Fidelity Select Health Care | 670.00K (0.83%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 14 | Fidelity Advisor Biotechnology I | 586.40K (0.73%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 15 | Fidelity Select Biotechnology | 562.50K (0.70%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 16 | Capital Group U.S. Small and Mid Cap ETF | 541.69K (0.67%) | 91.65K Increased by +16.92% | Apr 30, 26 |
| 17 | AB Discovery Growth A | 535.54K (0.66%) | 41.26K Increased by +7.70% | Jul 31, 25 |
| 18 | iShares Biotechnology ETF | 535.32K (0.66%) | 6.11K Increased by +1.14% | Apr 30, 26 |
| 19 | Jennison Health Sciences Equity | 534.10K (0.66%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 20 | PGIM Jennison Health Sciences Z | 534.10K (0.66%) | 0.00 Increased by 0.00% | Mar 31, 26 |