| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Nextech Invest AG | 12.07M (12.86%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | Nextech Invest, Ltd. | 12.07M (12.86%) | 12.07M Increased by +100.00% | Mar 31, 25 |
| 3 | EcoR1 Capital, LLC | 11.33M (12.07%) | -8.04M Decreased by -70.95% | Dec 31, 24 |
| 4 | Bain Capital Life Sciences Investors, LLC | 8.66M (9.23%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 5 | Vanguard Group Inc | 8.38M (8.93%) | 1.32M Increased by +15.76% | Mar 31, 25 |
| 6 | BlackRock Inc | 8.33M (8.87%) | -879.00K Decreased by -10.56% | Mar 31, 25 |
| 7 | State Street Corporation | 5.50M (5.86%) | 3.17M Increased by +57.63% | Mar 31, 24 |
| 8 | Bellevue Group AG | 5.22M (5.56%) | -800.00 Decreased by -0.02% | Sep 30, 23 |
| 9 | AQR Capital Management LLC | 5.14M (5.48%) | 5.14M Increased by +100.00% | Mar 31, 25 |
| 10 | Citadel Advisors Llc | 4.41M (4.70%) | 1.67M Increased by +37.81% | Sep 30, 24 |
| 11 | Novo A/S | 4.25M (4.53%) | 4.25M Increased by +100.00% | Dec 31, 24 |
| 12 | Rock Springs Capital Management LP | 3.81M (4.07%) | 383.00K Increased by +10.04% | Mar 31, 25 |
| 13 | Balyasny Asset Management LLC | 3.66M (3.90%) | -6.04M Decreased by -165.27% | Mar 31, 24 |
| 14 | VR Adviser, LLC | 3.57M (3.81%) | -6.68M Decreased by -186.99% | Mar 31, 25 |
| 15 | SILVERARC CAPITAL MANAGEMENT, LLC | 3.09M (3.29%) | 3.09M Increased by +100.00% | Mar 31, 25 |
| 16 | Acadian Asset Management LLC | 2.99M (3.19%) | 2.98M Increased by +99.60% | Mar 31, 25 |
| 17 | Boxer Capital Management, LLC | 2.63M (2.81%) | 2.63M Increased by +100.00% | Dec 31, 24 |
| 18 | State Street Corp | 2.60M (2.77%) | -161.03K Decreased by -6.18% | Mar 31, 25 |
| 19 | Cormorant Asset Management, LLC | 2.60M (2.77%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 20 | JPMorgan Chase & Co | 2.53M (2.70%) | -2.17M Decreased by -85.55% | Dec 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BB Biotech AG Ord | 5.21M (5.55%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 3.47M (3.70%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 3 | Vanguard US Total Market Shares ETF | 3.47M (3.70%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 4 | SPDR® S&P Biotech ETF | 3.01M (3.21%) | 5.82K Increased by +0.19% | May 31, 24 |
| 5 | iShares Russell 2000 ETF | 2.36M (2.51%) | 0.00 Increased by 0.00% | May 31, 25 |
| 6 | Vanguard Explorer Inv | 2.01M (2.14%) | 1.39M Increased by +69.36% | Mar 31, 25 |
| 7 | Vanguard Institutional Extnd Mkt Idx Tr | 1.52M (1.63%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 8 | Fidelity Small Cap Index | 1.11M (1.19%) | -26.25K Decreased by -2.36% | Mar 31, 25 |
| 9 | Fidelity® Small Cap Index | 1.02M (1.08%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 10 | State St Russell Sm/Mid Cp® Indx NL Cl C | 839.38K (0.89%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 11 | State St Russell Sm/Mid Cp® Indx SL Cl I | 839.38K (0.89%) | 0.00 Increased by 0.00% | May 31, 25 |
| 12 | Vanguard Russell 2000 ETF | 559.89K (0.60%) | 29.62K Increased by +5.29% | Apr 30, 25 |
| 13 | HealthInvest Sustainable Healthcare E | 538.62K (0.57%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 14 | Fidelity Extended Market Index | 526.10K (0.56%) | -5.03K Decreased by -0.96% | Apr 30, 25 |
| 15 | iShares Russell 2000 Growth ETF | 509.09K (0.54%) | 0.00 Increased by 0.00% | May 31, 25 |
| 16 | Fidelity® Extended Market Index | 508.16K (0.54%) | 83.33K Increased by +16.40% | Nov 30, 23 |
| 17 | iShares Russell 2000 Value ETF | 491.20K (0.52%) | 0.00 Increased by 0.00% | May 31, 25 |
| 18 | Bridgeway Ultra-Small Company | 475.50K (0.51%) | 243.20K Increased by +51.15% | Jun 30, 24 |
| 19 | iShares Biotechnology ETF | 471.40K (0.50%) | 0.00 Increased by 0.00% | May 31, 25 |
| 20 | Xtrackers MSCI World Swap ETF 1C | 449.40K (0.48%) | 0.00 Increased by 0.00% | Mar 31, 25 |