| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Nextech Invest AG | 12.07M (15.10%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | EcoR1 Capital, LLC | 11.33M (14.17%) | -8.04M Decreased by -70.95% | Dec 31, 24 |
| 3 | VR Adviser, LLC | 10.26M (12.83%) | -1.07M Decreased by -10.43% | Dec 31, 24 |
| 4 | BlackRock Inc | 9.21M (11.52%) | 583.32K Increased by +6.34% | Dec 31, 24 |
| 5 | Bain Capital Life Sciences Investors, LLC | 8.66M (10.84%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 6 | Vanguard Group Inc | 7.06M (8.83%) | -119.94K Decreased by -1.70% | Dec 31, 24 |
| 7 | State Street Corporation | 5.50M (6.88%) | 3.17M Increased by +57.63% | Mar 31, 24 |
| 8 | Bellevue Group AG | 5.22M (6.53%) | -800.00 Decreased by -0.02% | Sep 30, 23 |
| 9 | Citadel Advisors Llc | 4.41M (5.52%) | 1.67M Increased by +37.81% | Sep 30, 24 |
| 10 | Novo A/S | 4.25M (5.32%) | 4.25M Increased by +100.00% | Dec 31, 24 |
| 11 | Balyasny Asset Management LLC | 3.66M (4.57%) | -6.04M Decreased by -165.27% | Mar 31, 24 |
| 12 | Rock Springs Capital Management LP | 3.43M (4.29%) | 384.90K Increased by +11.22% | Dec 31, 24 |
| 13 | State Street Corp | 2.76M (3.46%) | 39.50K Increased by +1.43% | Dec 31, 24 |
| 14 | Boxer Capital Management, LLC | 2.63M (3.30%) | 2.63M Increased by +100.00% | Dec 31, 24 |
| 15 | Cormorant Asset Management, LLC | 2.60M (3.25%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 16 | JPMorgan Chase & Co | 2.53M (3.17%) | -2.17M Decreased by -85.55% | Dec 31, 24 |
| 17 | Geode Capital Management, LLC | 2.44M (3.06%) | 29.04K Increased by +1.19% | Dec 31, 24 |
| 18 | COMMODORE CAPITAL LP | 2.24M (2.81%) | 2.24M Increased by +100.00% | Sep 30, 23 |
| 19 | Schonfeld Strategic Advisors LLC | 2.12M (2.65%) | -103.72K Decreased by -4.89% | Dec 31, 24 |
| 20 | Walleye Trading Advisors, LLC | 2.02M (2.53%) | 1.87M Increased by +92.34% | Sep 30, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BB Biotech AG Ord | 5.21M (6.51%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 3.47M (4.34%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 3 | SPDR® S&P Biotech ETF | 3.01M (3.76%) | 5.82K Increased by +0.19% | May 31, 24 |
| 4 | iShares Russell 2000 ETF | 2.49M (3.12%) | -21.61K Decreased by -0.87% | Mar 31, 25 |
| 5 | Vanguard Institutional Extnd Mkt Idx Tr | 1.52M (1.91%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 6 | Fidelity Small Cap Index | 1.14M (1.43%) | -21.33K Decreased by -1.87% | Jan 31, 25 |
| 7 | Fidelity® Small Cap Index | 1.02M (1.27%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 8 | State St Russell Sm/Mid Cp® Indx NL Cl C | 839.38K (1.05%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 9 | Vanguard Explorer Inv | 614.97K (0.77%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 10 | HealthInvest Sustainable Healthcare E | 538.62K (0.67%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 11 | iShares Russell 2000 Growth ETF | 523.40K (0.65%) | -2.49K Decreased by -0.48% | Mar 31, 25 |
| 12 | Fidelity Extended Market Index | 519.93K (0.65%) | -3.31K Decreased by -0.64% | Feb 28, 25 |
| 13 | Vanguard Russell 2000 ETF | 518.50K (0.65%) | 12.06K Increased by +2.33% | Feb 28, 25 |
| 14 | iShares Biotechnology ETF | 516.25K (0.65%) | -5.75K Decreased by -1.11% | Mar 31, 25 |
| 15 | Fidelity® Extended Market Index | 508.16K (0.64%) | 83.33K Increased by +16.40% | Nov 30, 23 |
| 16 | iShares Russell 2000 Value ETF | 500.86K (0.63%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 17 | Bridgeway Ultra-Small Company | 475.50K (0.59%) | 243.20K Increased by +51.15% | Jun 30, 24 |
| 18 | Xtrackers MSCI World Swap ETF 1C | 449.40K (0.56%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 19 | State St Russell Sm Cap® Indx SL Cl I | 414.47K (0.52%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 20 | Vanguard VIF Small Co Gr | 408.39K (0.51%) | -59.24K Decreased by -14.51% | Dec 31, 24 |