| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Nextech Invest AG | 12.07M (296.97%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | Nextech Invest, Ltd. | 12.07M (296.97%) | 12.07M Increased by +100.00% | Mar 31, 25 |
| 3 | EcoR1 Capital, LLC | 11.33M (278.78%) | -8.04M Decreased by -70.95% | Dec 31, 24 |
| 4 | Bain Capital Life Sciences Investors, LLC | 8.66M (213.21%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 5 | Vanguard Group Inc | 8.38M (206.18%) | 1.32M Increased by +15.76% | Mar 31, 25 |
| 6 | BlackRock Inc | 8.33M (204.91%) | -879.00K Decreased by -10.56% | Mar 31, 25 |
| 7 | Schonfeld Strategic Advisors LLC | 7.61M (187.38%) | 5.49M Increased by +72.16% | Mar 31, 25 |
| 8 | State Street Corporation | 5.50M (135.29%) | 3.17M Increased by +57.63% | Mar 31, 24 |
| 9 | Bellevue Group AG | 5.22M (128.43%) | -800.00 Decreased by -0.02% | Sep 30, 23 |
| 10 | AQR Capital Management LLC | 5.14M (126.59%) | 5.14M Increased by +100.00% | Mar 31, 25 |
| 11 | Citadel Advisors Llc | 4.41M (108.57%) | 1.67M Increased by +37.81% | Sep 30, 24 |
| 12 | Novo A/S | 4.25M (104.59%) | 4.25M Increased by +100.00% | Dec 31, 24 |
| 13 | Rock Springs Capital Management LP | 3.81M (93.88%) | 383.00K Increased by +10.04% | Mar 31, 25 |
| 14 | Balyasny Asset Management LLC | 3.66M (89.97%) | -6.04M Decreased by -165.27% | Mar 31, 24 |
| 15 | VR Adviser, LLC | 3.57M (87.96%) | -6.68M Decreased by -186.99% | Mar 31, 25 |
| 16 | SILVERARC CAPITAL MANAGEMENT, LLC | 3.09M (76.01%) | 3.09M Increased by +100.00% | Mar 31, 25 |
| 17 | Acadian Asset Management LLC | 2.99M (73.57%) | 2.98M Increased by +99.60% | Mar 31, 25 |
| 18 | Boxer Capital Management, LLC | 2.63M (64.85%) | 2.63M Increased by +100.00% | Dec 31, 24 |
| 19 | State Street Corp | 2.60M (64.08%) | -161.03K Decreased by -6.18% | Mar 31, 25 |
| 20 | Cormorant Asset Management, LLC | 2.60M (63.99%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BB Biotech AG Ord | 5.21M (128.12%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 2 | Vanguard US Total Market Shares ETF | 3.47M (85.42%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 3 | SPDR® S&P Biotech ETF | 3.01M (74.04%) | 5.82K Increased by +0.19% | May 31, 24 |
| 4 | Vanguard Explorer Inv | 2.01M (49.39%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 5 | Vanguard Institutional Extnd Mkt Idx Tr | 1.52M (37.53%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 6 | Fidelity Small Cap Index | 1.11M (27.35%) | 0.00 Increased by 0.00% | May 31, 25 |
| 7 | Fidelity® Small Cap Index | 1.02M (25.01%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 8 | State St Russell Sm/Mid Cp® Indx NL Cl C | 839.38K (20.66%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 9 | State St Russell Sm/Mid Cp® Indx SL Cl I | 839.38K (20.66%) | 0.00 Increased by 0.00% | May 31, 25 |
| 10 | iShares Biotechnology ETF | 625.00K (15.38%) | -2.26K Decreased by -0.36% | Jun 30, 25 |
| 11 | iShares Russell 2000 ETF | 569.31K (14.01%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 12 | Vanguard Russell 2000 ETF | 564.71K (13.90%) | 4.82K Increased by +0.85% | May 31, 25 |
| 13 | HealthInvest Sustainable Healthcare E | 538.62K (13.26%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 14 | Fidelity Extended Market Index | 522.39K (12.86%) | -1.36K Decreased by -0.26% | Jun 30, 25 |
| 15 | Fidelity® Extended Market Index | 508.16K (12.51%) | 83.33K Increased by +16.40% | Nov 30, 23 |
| 16 | Bridgeway Ultra-Small Company | 475.50K (11.70%) | 243.20K Increased by +51.15% | Jun 30, 24 |
| 17 | Xtrackers MSCI World Swap ETF 1C | 449.40K (11.06%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 18 | State St Russell Sm Cap® Indx SL Cl I | 414.47K (10.20%) | 0.00 Increased by 0.00% | May 31, 25 |
| 19 | Vanguard VIF Small Co Gr | 408.39K (10.05%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 20 | JPMorgan US Small Company L | 403.74K (9.94%) | -11.73K Decreased by -2.91% | Dec 31, 24 |