| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Nextech Invest AG | 12.07M (321.50%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | Nextech Invest, Ltd. | 12.07M (321.50%) | 12.07M Increased by +100.00% | Mar 31, 25 |
| 3 | EcoR1 Capital, LLC | 11.33M (301.81%) | -8.04M Decreased by -70.95% | Dec 31, 24 |
| 4 | Bain Capital Life Sciences Investors, LLC | 8.66M (230.82%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 5 | Vanguard Group Inc | 8.38M (223.20%) | 1.32M Increased by +15.76% | Mar 31, 25 |
| 6 | BlackRock Inc | 8.33M (221.83%) | -879.00K Decreased by -10.56% | Mar 31, 25 |
| 7 | Schonfeld Strategic Advisors LLC | 7.61M (202.86%) | 5.49M Increased by +72.16% | Mar 31, 25 |
| 8 | State Street Corporation | 5.50M (146.47%) | 3.17M Increased by +57.63% | Mar 31, 24 |
| 9 | Bellevue Group AG | 5.22M (139.04%) | -800.00 Decreased by -0.02% | Sep 30, 23 |
| 10 | AQR Capital Management LLC | 5.14M (137.04%) | 5.14M Increased by +100.00% | Mar 31, 25 |
| 11 | Citadel Advisors Llc | 4.41M (117.53%) | 1.67M Increased by +37.81% | Sep 30, 24 |
| 12 | Novo A/S | 4.25M (113.23%) | 4.25M Increased by +100.00% | Dec 31, 24 |
| 13 | Rock Springs Capital Management LP | 3.81M (101.63%) | 383.00K Increased by +10.04% | Mar 31, 25 |
| 14 | Balyasny Asset Management LLC | 3.66M (97.41%) | -6.04M Decreased by -165.27% | Mar 31, 24 |
| 15 | VR Adviser, LLC | 3.57M (95.23%) | -6.68M Decreased by -186.99% | Mar 31, 25 |
| 16 | SILVERARC CAPITAL MANAGEMENT, LLC | 3.09M (82.29%) | 3.09M Increased by +100.00% | Mar 31, 25 |
| 17 | Acadian Asset Management LLC | 2.99M (79.65%) | 2.98M Increased by +99.60% | Mar 31, 25 |
| 18 | Boxer Capital Management, LLC | 2.63M (70.20%) | 2.63M Increased by +100.00% | Dec 31, 24 |
| 19 | State Street Corp | 2.60M (69.37%) | -161.03K Decreased by -6.18% | Mar 31, 25 |
| 20 | Cormorant Asset Management, LLC | 2.60M (69.27%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BB Biotech AG Ord | 5.21M (138.70%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 3.47M (92.47%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 3 | Vanguard US Total Market Shares ETF | 3.47M (92.47%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 4 | SPDR® S&P Biotech ETF | 3.01M (80.16%) | 5.82K Increased by +0.19% | May 31, 24 |
| 5 | Vanguard Explorer Inv | 2.01M (53.47%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 6 | Vanguard Institutional Extnd Mkt Idx Tr | 1.52M (40.63%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 7 | Fidelity Small Cap Index | 1.11M (29.61%) | 0.00 Increased by 0.00% | May 31, 25 |
| 8 | Fidelity® Small Cap Index | 1.02M (27.08%) | 0.00 Increased by 0.00% | Oct 31, 23 |
| 9 | State St Russell Sm/Mid Cp® Indx NL Cl C | 839.38K (22.36%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 10 | State St Russell Sm/Mid Cp® Indx SL Cl I | 839.38K (22.36%) | 0.00 Increased by 0.00% | May 31, 25 |
| 11 | iShares Biotechnology ETF | 625.00K (16.65%) | -2.26K Decreased by -0.36% | Jun 30, 25 |
| 12 | iShares Russell 2000 ETF | 569.31K (15.17%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 13 | Vanguard Russell 2000 ETF | 564.71K (15.05%) | 4.82K Increased by +0.85% | May 31, 25 |
| 14 | HealthInvest Sustainable Healthcare E | 538.62K (14.35%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 15 | Fidelity Extended Market Index | 522.39K (13.92%) | -1.36K Decreased by -0.26% | Jun 30, 25 |
| 16 | Fidelity® Extended Market Index | 508.16K (13.54%) | 83.33K Increased by +16.40% | Nov 30, 23 |
| 17 | Bridgeway Ultra-Small Company | 475.50K (12.67%) | 243.20K Increased by +51.15% | Jun 30, 24 |
| 18 | Xtrackers MSCI World Swap ETF 1C | 449.40K (11.97%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 19 | State St Russell Sm Cap® Indx SL Cl I | 414.47K (11.04%) | 0.00 Increased by 0.00% | May 31, 25 |
| 20 | Vanguard VIF Small Co Gr | 408.39K (10.88%) | 0.00 Increased by 0.00% | Jun 30, 25 |