| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 28.95M (9.55%) | 239.38K Increased by +0.83% | Dec 31, 25 |
| 2 | Vanguard Group Inc | 17.88M (5.90%) | 250.29K Increased by +1.40% | Dec 31, 25 |
| 3 | State Street Corp | 14.62M (4.82%) | 3.88M Increased by +26.55% | Dec 31, 25 |
| 4 | State Street Corporation | 11.94M (3.94%) | -999.00K Decreased by -8.37% | Mar 31, 24 |
| 5 | UBS Group AG | 8.26M (2.72%) | 3.15M Increased by +38.18% | Mar 31, 26 |
| 6 | Geode Capital Management, LLC | 7.37M (2.43%) | -11.38K Decreased by -0.15% | Dec 31, 25 |
| 7 | Nitorum Capital, L.P. | 5.33M (1.76%) | -1.24M Decreased by -23.20% | Dec 31, 25 |
| 8 | Dimensional Fund Advisors, Inc. | 4.95M (1.63%) | 509.69K Increased by +10.29% | Mar 31, 26 |
| 9 | Millennium Management LLC | 4.48M (1.48%) | -1.34M Decreased by -29.92% | Jun 30, 25 |
| 10 | Morgan Stanley - Brokerage Accounts | 4.44M (1.47%) | 593.47K Increased by +13.35% | Dec 31, 25 |
| 11 | Frazier Life Sciences Management, L.P. | 4.22M (1.39%) | 4.22M Increased by +100.00% | Dec 31, 25 |
| 12 | JPMorgan Chase & Co | 4.10M (1.35%) | 2.74M Increased by +66.99% | Sep 30, 25 |
| 13 | Rubric Capital Management LP | 3.62M (1.19%) | -3.86M Decreased by -106.51% | Mar 31, 26 |
| 14 | FMR Inc | 3.58M (1.18%) | 258.77K Increased by +7.23% | Dec 31, 25 |
| 15 | Citadel Advisors Llc | 3.57M (1.18%) | 2.27M Increased by +63.59% | Dec 31, 25 |
| 16 | Two Sigma Advisers, LLC | 3.39M (1.12%) | -348.90K Decreased by -10.30% | Jun 30, 25 |
| 17 | TSP Capital Management Group/LLC | 3.34M (1.10%) | 380.80K Increased by +11.39% | Mar 31, 26 |
| 18 | Wellington Management Company LLP | 3.31M (1.09%) | -162.71K Decreased by -4.92% | Dec 31, 25 |
| 19 | 180 WEALTH ADVISORS, LLC | 2.96M (0.98%) | 86.66K Increased by +2.93% | Dec 31, 25 |
| 20 | Arrowstreet Capital Limited Partnership | 2.72M (0.90%) | -2.17M Decreased by -79.93% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | State Street® SPDR® S&P® Biotech ETF | 12.22M (4.03%) | -86.74K Decreased by -0.71% | Apr 30, 26 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 9.15M (3.02%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 3 | Vanguard US Total Market Shares ETF | 8.09M (2.67%) | -22.90K Decreased by -0.28% | Sep 30, 24 |
| 4 | iShares Russell 2000 ETF | 7.17M (2.37%) | 60.44K Increased by +0.84% | Apr 30, 26 |
| 5 | Fidelity® Select Biotechnology | 5.93M (1.96%) | -518.10K Decreased by -8.74% | Nov 30, 23 |
| 6 | Vanguard Institutional Extnd Mkt Idx Tr | 3.43M (1.13%) | 80.81K Increased by +2.35% | Mar 31, 26 |
| 7 | Fidelity Select Biotechnology | 3.18M (1.05%) | 997.10K Increased by +31.33% | Mar 31, 26 |
| 8 | Fidelity Small Cap Index | 2.95M (0.97%) | 28.61K Increased by +0.97% | Feb 28, 26 |
| 9 | SPDR® S&P Biotech ETF | 2.87M (0.95%) | 6.40K Increased by +0.22% | Aug 31, 25 |
| 10 | iShares Russell 2000 Growth ETF | 2.50M (0.83%) | 6.45K Increased by +0.26% | Apr 30, 26 |
| 11 | Fidelity® Small Cap Index | 2.47M (0.81%) | 65.46K Increased by +2.65% | Oct 31, 23 |
| 12 | iShares Biotechnology ETF | 2.20M (0.72%) | 42.01K Increased by +1.91% | Apr 30, 26 |
| 13 | Russell 2000 Equity Index Fund B | 1.90M (0.63%) | -63.14K Decreased by -3.33% | Dec 31, 25 |
| 14 | State St Russell Sm/Mid Cp® Indx SL Cl I | 1.77M (0.58%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 15 | Fidelity Extended Market Index | 1.64M (0.54%) | 40.37K Increased by +2.46% | Mar 31, 26 |
| 16 | State St Russell Sm/Mid Cp® Indx NL Cl C | 1.55M (0.51%) | 7.57K Increased by +0.49% | Apr 30, 25 |
| 17 | Nuveen Quant Small Cap Equity R6 | 1.53M (0.50%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 18 | Vanguard Russell 2000 ETF | 1.51M (0.50%) | 6.25K Increased by +0.42% | Mar 31, 26 |
| 19 | Schwab US Small-Cap ETF™ | 1.49M (0.49%) | -109.00 Decreased by -0.01% | Apr 30, 26 |
| 20 | Fidelity® Extended Market Index | 1.44M (0.48%) | 0.00 Increased by 0.00% | Nov 30, 23 |