| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Bvf Inc | 19.75M (69.73%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 2 | Cormorant Asset Management, LLC | 8.49M (29.99%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 3 | FMR Inc | 6.33M (22.34%) | -14.38K Decreased by -0.23% | Mar 31, 25 |
| 4 | T. Rowe Price Associates, Inc. | 2.97M (10.50%) | -369.81K Decreased by -12.44% | Mar 31, 25 |
| 5 | venBio Select Advisor LLC | 2.77M (9.78%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 6 | Holocene Advisors, LP | 1.59M (5.60%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 7 | Citadel Advisors Llc | 1.48M (5.22%) | -708.23K Decreased by -47.90% | Mar 31, 25 |
| 8 | Westfield Capital Management Company, L.P. | 1.43M (5.07%) | 123.15K Increased by +8.58% | Mar 31, 25 |
| 9 | Goldman Sachs Group Inc | 1.29M (4.56%) | -382.06K Decreased by -29.56% | Mar 31, 25 |
| 10 | Federated Hermes Inc | 1.27M (4.48%) | -10.70K Decreased by -0.84% | Mar 31, 25 |
| 11 | Westfield Capital Management Company, LP | 1.17M (4.12%) | 49.73K Increased by +4.26% | Sep 30, 24 |
| 12 | Polar Capital Holdings PLC | 1.10M (3.88%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 13 | T. Rowe Price Investment Management,Inc. | 1.10M (3.87%) | -125.50K Decreased by -11.46% | Mar 31, 24 |
| 14 | Darwin Global Management, Ltd. | 1.04M (3.67%) | 1.04M Increased by +100.00% | Dec 31, 23 |
| 15 | AllianceBernstein L.P. | 966.09K (3.41%) | -56.51K Decreased by -5.85% | Mar 31, 25 |
| 16 | ING Investment Management LLC | 785.85K (2.77%) | 336.99K Increased by +42.88% | Mar 31, 25 |
| 17 | Avidity Partners Management LP | 777.17K (2.74%) | 377.17K Increased by +48.53% | Sep 30, 23 |
| 18 | Nuveen, LLC | 673.34K (2.38%) | 673.34K Increased by +100.00% | Mar 31, 25 |
| 19 | Hood River Capital Management LLC | 662.98K (2.34%) | 13.39K Increased by +2.02% | Mar 31, 25 |
| 20 | Fred Alger Management, LLC | 642.88K (2.27%) | -30.89K Decreased by -4.81% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | T. Rowe Price Health Sciences | 1.28M (4.53%) | -183.82K Decreased by -14.32% | Mar 31, 25 |
| 2 | Polar Capital Biotech S Inc | 1.00M (3.53%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 3 | Fidelity Select Health Care | 752.79K (2.66%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 4 | Harbor Small Cap Growth Instl | 704.82K (2.49%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 5 | Westfield Capital Mgt Co Sm-Cap Gr Eq | 704.82K (2.49%) | 56.75K Increased by +8.05% | Mar 31, 25 |
| 6 | Fidelity Growth Compy Commingled Pl S | 687.62K (2.43%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 7 | Federated Hermes Kaufmann Growth | 665.00K (2.35%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 8 | Federated Hermes Kaufmann R | 665.00K (2.35%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 9 | T. Rowe Price New Horizons | 658.08K (2.32%) | -8.90K Decreased by -1.35% | Mar 31, 25 |
| 10 | US Small-Cap Growth II Equity Comp | 658.08K (2.32%) | -9.09K Decreased by -1.38% | Mar 31, 25 |
| 11 | T. Rowe Price Integrated US SmCapGrEq | 598.31K (2.11%) | 299.16K Increased by +50.00% | Dec 31, 24 |
| 12 | Federated Hermes Kaufmann Small Cap A | 519.00K (1.83%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 13 | Federated Hermes Kaufmann Small Cap Grow | 519.00K (1.83%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 14 | Fidelity Select Biotechnology | 510.86K (1.80%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 15 | Fidelity Contrafund | 494.78K (1.75%) | -454.00 Decreased by -0.09% | Mar 31, 24 |
| 16 | Fidelity® Contrafund® | 493.74K (1.74%) | 80.19K Increased by +16.24% | Oct 31, 23 |
| 17 | Alger Small Cap Focus Composite | 483.56K (1.71%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 18 | Alger Small Cap Focus I | 483.56K (1.71%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 19 | Fidelity Growth Company Fund | 477.36K (1.69%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 20 | MEDICAL BioHealth EUR Acc | 452.69K (1.60%) | 175.96K Increased by +38.87% | Mar 31, 25 |