| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Bvf Inc | 19.75M (60.67%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 2 | Cormorant Asset Management, LLC | 8.49M (26.09%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 3 | FMR Inc | 5.73M (17.60%) | -596.47K Decreased by -10.41% | Jun 30, 25 |
| 4 | venBio Select Advisor LLC | 4.15M (12.75%) | 1.38M Increased by +33.25% | Jun 30, 25 |
| 5 | T. Rowe Price Associates, Inc. | 2.61M (8.03%) | -360.60K Decreased by -13.80% | Jun 30, 25 |
| 6 | Citadel Advisors Llc | 1.67M (5.14%) | 195.41K Increased by +11.67% | Jun 30, 25 |
| 7 | Holocene Advisors, LP | 1.59M (4.87%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 8 | Goldman Sachs Group Inc | 1.28M (3.92%) | -17.04K Decreased by -1.34% | Jun 30, 25 |
| 9 | Westfield Capital Management Company, L.P. | 1.26M (3.87%) | -175.39K Decreased by -13.93% | Jun 30, 25 |
| 10 | Federated Hermes Inc | 1.25M (3.84%) | -20.78K Decreased by -1.66% | Jun 30, 25 |
| 11 | Westfield Capital Management Company, LP | 1.17M (3.59%) | 49.73K Increased by +4.26% | Sep 30, 24 |
| 12 | AllianceBernstein L.P. | 1.14M (3.50%) | 171.93K Increased by +15.11% | Jun 30, 25 |
| 13 | Polar Capital Holdings PLC | 1.10M (3.38%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 14 | T. Rowe Price Investment Management,Inc. | 1.10M (3.36%) | -125.50K Decreased by -11.46% | Mar 31, 24 |
| 15 | Darwin Global Management, Ltd. | 1.04M (3.19%) | 1.04M Increased by +100.00% | Dec 31, 23 |
| 16 | Paradigm Biocapital Advisors LP | 878.32K (2.70%) | 250.90K Increased by +28.57% | Jun 30, 25 |
| 17 | Nuveen, LLC | 791.55K (2.43%) | 118.21K Increased by +14.93% | Jun 30, 25 |
| 18 | ING Investment Management LLC | 785.85K (2.41%) | 336.99K Increased by +42.88% | Mar 31, 25 |
| 19 | Avidity Partners Management LP | 777.17K (2.39%) | 377.17K Increased by +48.53% | Sep 30, 23 |
| 20 | RTW INVESTMENTS, LLC | 741.09K (2.28%) | 741.09K Increased by +100.00% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | T. Rowe Price Health Sciences | 1.04M (3.20%) | -55.57K Decreased by -5.34% | Jul 31, 25 |
| 2 | Polar Capital Biotech S Inc | 1.00M (3.07%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 3 | Fidelity Growth Compy Commingled Pl S | 981.02K (3.01%) | 273.63K Increased by +27.89% | Jul 31, 25 |
| 4 | Fidelity Growth Company Fund | 740.92K (2.28%) | 248.13K Increased by +33.49% | Jul 31, 25 |
| 5 | Federated Hermes Kaufmann Growth | 665.00K (2.04%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 6 | Federated Hermes Kaufmann R | 665.00K (2.04%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 7 | US Small-Cap Growth II Equity Comp | 523.89K (1.61%) | -134.19K Decreased by -25.62% | Jun 30, 25 |
| 8 | Fidelity Select Health Care | 520.00K (1.60%) | -150.00K Decreased by -28.85% | Jul 31, 25 |
| 9 | Fidelity Select Biotechnology | 518.86K (1.59%) | -86.20K Decreased by -16.61% | Jul 31, 25 |
| 10 | Federated Hermes Kaufmann Small Cap A | 503.00K (1.55%) | -16.00K Decreased by -3.18% | Jun 30, 25 |
| 11 | Federated Hermes Kaufmann Small Cap Grow | 503.00K (1.55%) | -16.00K Decreased by -3.18% | Jun 30, 25 |
| 12 | Fidelity Contrafund | 494.78K (1.52%) | -454.00 Decreased by -0.09% | Mar 31, 24 |
| 13 | Fidelity® Contrafund® | 493.74K (1.52%) | 80.19K Increased by +16.24% | Oct 31, 23 |
| 14 | MEDICAL BioHealth EUR Acc | 452.69K (1.39%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 15 | Fidelity Growth Compy Commingled Pl O | 442.87K (1.36%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 16 | T. Rowe Price Small-Cap Stock | 421.42K (1.29%) | 31.52K Increased by +7.48% | Mar 31, 24 |
| 17 | T. Rowe Price US Small-Cap Core Equity | 421.42K (1.29%) | 31.52K Increased by +7.48% | Mar 31, 24 |
| 18 | Pictet-Biotech P USD | 406.15K (1.25%) | -58.93K Decreased by -14.51% | Jul 31, 23 |
| 19 | Fidelity® Blue Chip Growth | 396.52K (1.22%) | -679.00 Decreased by -0.17% | Oct 31, 23 |
| 20 | Strategic Advisers Fidelity US TtlStk | 394.67K (1.21%) | 3.39K Increased by +0.86% | May 31, 25 |