| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | HHG PLC | 5.24M (13.10%) | 470.17K Increased by +8.98% | Jun 30, 25 |
| 2 | BlackRock Inc | 3.58M (8.95%) | 237.53K Increased by +6.64% | Jun 30, 25 |
| 3 | State Street Corporation | 2.82M (7.06%) | 1.09M Increased by +38.54% | Mar 31, 24 |
| 4 | Bvf Inc | 2.76M (6.91%) | -35.18K Decreased by -1.27% | Jun 30, 25 |
| 5 | Eventide Asset Management, LLC | 2.64M (6.60%) | 110.48K Increased by +4.19% | Jun 30, 25 |
| 6 | Vanguard Group Inc | 2.56M (6.42%) | 24.81K Increased by +0.97% | Jun 30, 25 |
| 7 | NEA Management Company, LLC | 2.19M (5.47%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 8 | Novo A/S | 1.50M (3.75%) | 55.00 Increased by +0.00% | Jun 30, 25 |
| 9 | T. Rowe Price Associates, Inc. | 1.42M (3.55%) | 2.08K Increased by +0.15% | Jun 30, 25 |
| 10 | Citadel Advisors Llc | 1.41M (3.52%) | -39.64K Decreased by -2.82% | Jun 30, 25 |
| 11 | State Street Corp | 1.38M (3.44%) | -118.94K Decreased by -8.65% | Jun 30, 25 |
| 12 | TANG CAPITAL MANAGEMENT LLC | 1.24M (3.09%) | -1.08K Decreased by -0.09% | Jun 30, 25 |
| 13 | Cadian Capital Management LP | 1.24M (3.09%) | -1.06M Decreased by -85.61% | Jun 30, 24 |
| 14 | Wagonhound Investments, LP | 1.20M (3.00%) | 284.25K Increased by +23.70% | Sep 30, 23 |
| 15 | Geode Capital Management, LLC | 1.03M (2.58%) | 65.95K Increased by +6.41% | Jun 30, 25 |
| 16 | ClearBridge Advisors, LLC | 1.03M (2.57%) | 49.46K Increased by +4.81% | Jun 30, 25 |
| 17 | Polar Capital Holdings PLC | 975.00K (2.44%) | -200.00K Decreased by -20.51% | Jun 30, 25 |
| 18 | Rock Springs Capital Management LP | 818.21K (2.05%) | -133.56K Decreased by -16.32% | Jun 30, 25 |
| 19 | Lord, Abbett & Co LLC | 771.15K (1.93%) | -42.25K Decreased by -5.48% | Jun 30, 25 |
| 20 | Nuveen Asset Management, LLC | 722.15K (1.81%) | 229.75K Increased by +31.81% | Dec 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Eventide Gilead N | 1.43M (3.58%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 2 | Vanguard US Total Market Shares ETF | 1.41M (3.52%) | 1.77K Increased by +0.13% | Sep 30, 24 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 1.34M (3.35%) | -28.37K Decreased by -2.12% | Jul 31, 25 |
| 4 | Eventide Healthcare & Life Sciences I | 1.19M (2.99%) | 108.58K Increased by +9.09% | Jun 30, 25 |
| 5 | iShares Russell 2000 ETF | 1.05M (2.62%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 6 | Polar Capital Biotech S Inc | 975.00K (2.44%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 7 | Janus Henderson Global Life Sciences | 774.99K (1.94%) | 62.59K Increased by +8.08% | Jun 30, 25 |
| 8 | Janus Henderson Global Life Sciences D | 774.99K (1.94%) | -3.15K Decreased by -0.41% | Jun 30, 25 |
| 9 | MEDICAL BioHealth EUR Acc | 756.50K (1.89%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 10 | US Small-Cap Growth II Equity Comp | 716.26K (1.79%) | -40.98K Decreased by -5.72% | Jun 30, 25 |
| 11 | ClearBridge Small Cap Growth A | 706.79K (1.77%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 12 | Janus Selection Global Life Science AUSD | 700.63K (1.75%) | 265.57K Increased by +37.90% | Jun 30, 24 |
| 13 | ClearBridge Small Cap Growth | 699.09K (1.75%) | -7.70K Decreased by -1.10% | Jul 31, 25 |
| 14 | Janus Henderson Triton D | 679.10K (1.70%) | -8.01K Decreased by -1.18% | Jun 30, 25 |
| 15 | Janus Henderson US SMID Cap Growth | 679.10K (1.70%) | -8.01K Decreased by -1.18% | Jun 30, 25 |
| 16 | Janus Henderson US SMID Cap Growth MA | 679.10K (1.70%) | 679.10K Increased by +100.00% | Jun 30, 25 |
| 17 | Janus Global Life Science AUSD | 641.26K (1.60%) | 64.26K Increased by +10.02% | Jun 30, 25 |
| 18 | Janus Henderson Glb Life Scn I2 USD | 635.14K (1.59%) | -4.45K Decreased by -0.70% | Jul 31, 25 |
| 19 | T. Rowe Price New Horizons | 627.48K (1.57%) | -88.79K Decreased by -14.15% | Jul 31, 25 |
| 20 | Franklin Biotechnology Discv A(acc)USD | 555.15K (1.39%) | -71.10K Decreased by -12.81% | Jul 31, 24 |