| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Bellevue Group AG | 9.92M (18.87%) | -9.97K Decreased by -0.10% | Jun 30, 25 |
| 2 | venBio Select Advisor LLC | 6.15M (11.70%) | 6.15M Increased by +100.00% | Mar 31, 24 |
| 3 | Armistice Capital, LLC | 5.96M (11.34%) | -336.00K Decreased by -5.64% | Jun 30, 25 |
| 4 | BlackRock Inc | 4.91M (9.35%) | -144.05K Decreased by -2.93% | Mar 31, 25 |
| 5 | State Street Corporation | 4.39M (8.35%) | 2.22M Increased by +50.47% | Mar 31, 24 |
| 6 | Vanguard Group Inc | 4.21M (8.02%) | -212.88K Decreased by -5.05% | Jun 30, 25 |
| 7 | Wasatch Advisors LP | 3.25M (6.19%) | 774.00 Increased by +0.02% | Jun 30, 25 |
| 8 | T. Rowe Price Investment Management,Inc. | 2.77M (5.26%) | -2.87M Decreased by -103.83% | Mar 31, 24 |
| 9 | Acadian Asset Management LLC | 2.31M (4.39%) | 2.31M Increased by +99.93% | Mar 31, 25 |
| 10 | RA Capital Management, LLC | 2.08M (3.96%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 11 | Millennium Management LLC | 1.72M (3.28%) | -1.14M Decreased by -66.14% | Mar 31, 25 |
| 12 | EcoR1 Capital, LLC | 1.60M (3.05%) | 1.60M Increased by +100.00% | Jun 30, 25 |
| 13 | Geode Capital Management, LLC | 1.46M (2.77%) | 22.97K Increased by +1.58% | Mar 31, 25 |
| 14 | State Street Corp | 1.41M (2.68%) | -53.22K Decreased by -3.78% | Mar 31, 25 |
| 15 | Wasatch Advisors Inc. | 1.30M (2.47%) | -111.96K Decreased by -8.63% | Dec 31, 23 |
| 16 | SILVERARC CAPITAL MANAGEMENT, LLC | 1.26M (2.39%) | -5.52K Decreased by -0.44% | Dec 31, 23 |
| 17 | T. Rowe Price Associates, Inc. | 1.25M (2.39%) | -82.78K Decreased by -6.60% | Sep 30, 24 |
| 18 | Renaissance Technologies Corp | 1.15M (2.19%) | 613.75K Increased by +53.26% | Mar 31, 25 |
| 19 | Rock Springs Capital Management LP | 1.15M (2.18%) | 91.57K Increased by +8.00% | Mar 31, 25 |
| 20 | Morgan Stanley - Brokerage Accounts | 1.10M (2.10%) | 784.56K Increased by +71.04% | Dec 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BB Biotech AG Ord | 9.93M (18.89%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | Wasatch Ultra Growth | 2.82M (5.37%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 3 | SPDR® S&P Biotech ETF | 2.78M (5.29%) | -37.04K Decreased by -1.33% | Apr 30, 24 |
| 4 | Vanguard US Total Market Shares ETF | 2.00M (3.81%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 5 | Vanguard Total Stock Mkt Idx Inv | 1.93M (3.67%) | -42.58K Decreased by -2.20% | Jul 31, 25 |
| 6 | Wasatch Micro Cap | 773.76K (1.47%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 7 | T. Rowe Price New Horizons | 750.71K (1.43%) | 750.71K Increased by +100.00% | Mar 31, 24 |
| 8 | US Small-Cap Growth II Equity Comp | 750.71K (1.43%) | 750.71K Increased by +100.00% | Mar 31, 24 |
| 9 | T. Rowe Price Small-Cap Stock | 707.16K (1.35%) | -665.30K Decreased by -94.08% | Mar 31, 24 |
| 10 | T. Rowe Price US Small-Cap Core Equity | 707.16K (1.35%) | -665.30K Decreased by -94.08% | Mar 31, 24 |
| 11 | T. Rowe Price Small-Cap Value | 679.96K (1.29%) | -966.34K Decreased by -142.12% | Mar 31, 24 |
| 12 | T. Rowe Price U.S. SC Core Eq Tr-Z | 670.71K (1.28%) | 70.60K Increased by +10.53% | Dec 31, 23 |
| 13 | Vanguard Institutional Extnd Mkt Idx Tr | 639.64K (1.22%) | -291.46K Decreased by -45.57% | Jul 31, 25 |
| 14 | Fidelity Small Cap Index | 633.43K (1.21%) | -6.51K Decreased by -1.03% | May 31, 25 |
| 15 | Fidelity® Small Cap Index | 588.71K (1.12%) | 17.84K Increased by +3.03% | Oct 31, 23 |
| 16 | Federated Hermes MDT SCC Institutional | 550.65K (1.05%) | -86.61K Decreased by -15.73% | Dec 31, 23 |
| 17 | T. Rowe Price Instl Small-Cap Stock | 523.38K (1.00%) | 113.70K Increased by +21.72% | Dec 31, 23 |
| 18 | JPMorgan Small Cap Value I | 510.51K (0.97%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 19 | State St Russell Sm/Mid Cp® Indx NL Cl C | 476.20K (0.91%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 20 | State St Russell Sm/Mid Cp® Indx SL Cl I | 476.20K (0.91%) | 0.00 Increased by 0.00% | May 31, 25 |