| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Bellevue Group AG | 9.92M (18.92%) | -9.97K Decreased by -0.10% | Jun 30, 25 |
| 2 | venBio Select Advisor LLC | 6.15M (11.73%) | 6.15M Increased by +100.00% | Mar 31, 24 |
| 3 | Armistice Capital, LLC | 6.01M (11.46%) | -312.00K Decreased by -5.19% | Mar 31, 26 |
| 4 | State Street Corporation | 4.39M (8.37%) | 2.22M Increased by +50.47% | Mar 31, 24 |
| 5 | Vanguard Group Inc | 4.23M (8.06%) | 2.71K Increased by +0.06% | Dec 31, 25 |
| 6 | Renaissance Technologies Corp | 2.96M (5.65%) | 54.93K Increased by +1.85% | Mar 31, 26 |
| 7 | Millennium Management LLC | 2.79M (5.33%) | 819.88K Increased by +29.34% | Mar 31, 26 |
| 8 | T. Rowe Price Investment Management,Inc. | 2.77M (5.28%) | -2.87M Decreased by -103.83% | Mar 31, 24 |
| 9 | Vanguard Capital Management, LLC | 2.65M (5.06%) | 2.65M Increased by +100.00% | Mar 31, 26 |
| 10 | Acadian Asset Management LLC | 2.54M (4.85%) | 2.54M Increased by +99.95% | Mar 31, 26 |
| 11 | Two Sigma Investments LLC | 2.53M (4.82%) | 1.53M Increased by +60.46% | Mar 31, 26 |
| 12 | Bank of America Corp | 2.40M (4.58%) | 564.09K Increased by +23.49% | Mar 31, 26 |
| 13 | Marshall Wace Asset Management Ltd | 2.03M (3.86%) | 740.96K Increased by +36.58% | Mar 31, 26 |
| 14 | RA Capital Management, LLC | 1.86M (3.55%) | 1.86M Increased by +100.00% | Mar 31, 26 |
| 15 | Jefferies Financial Group Inc | 1.84M (3.51%) | 1.84M Increased by +100.00% | Dec 31, 25 |
| 16 | EcoR1 Capital, LLC | 1.60M (3.06%) | 1.60M Increased by +100.00% | Jun 30, 25 |
| 17 | Wasatch Advisors LP | 1.56M (2.97%) | -226.66K Decreased by -14.53% | Mar 31, 26 |
| 18 | JPMorgan Chase & Co | 1.51M (2.88%) | 1.05M Increased by +69.54% | Sep 30, 25 |
| 19 | State Street Corp | 1.41M (2.69%) | -53.22K Decreased by -3.78% | Mar 31, 25 |
| 20 | Wasatch Advisors Inc. | 1.30M (2.47%) | -111.96K Decreased by -8.63% | Dec 31, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BB Biotech AG Ord | 9.92M (18.92%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 2 | SPDR® S&P Biotech ETF | 2.78M (5.30%) | -37.04K Decreased by -1.33% | Apr 30, 24 |
| 3 | Vanguard US Total Market Shares ETF | 2.00M (3.82%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 4 | Vanguard Total Stock Mkt Idx Inv | 1.93M (3.67%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 5 | Wasatch Ultra Growth | 1.43M (2.73%) | -228.06K Decreased by -15.90% | Mar 31, 26 |
| 6 | Wasatch Micro Cap | 773.76K (1.48%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 7 | T. Rowe Price New Horizons | 750.71K (1.43%) | 750.71K Increased by +100.00% | Mar 31, 24 |
| 8 | US Small-Cap Growth II Equity Comp | 750.71K (1.43%) | 750.71K Increased by +100.00% | Mar 31, 24 |
| 9 | T. Rowe Price Small-Cap Stock | 707.16K (1.35%) | -665.30K Decreased by -94.08% | Mar 31, 24 |
| 10 | T. Rowe Price US Small-Cap Core Equity | 707.16K (1.35%) | -665.30K Decreased by -94.08% | Mar 31, 24 |
| 11 | T. Rowe Price Small-Cap Value | 679.96K (1.30%) | -966.34K Decreased by -142.12% | Mar 31, 24 |
| 12 | T. Rowe Price U.S. SC Core Eq Tr-Z | 670.71K (1.28%) | 70.60K Increased by +10.53% | Dec 31, 23 |
| 13 | Vanguard Institutional Extnd Mkt Idx Tr | 651.75K (1.24%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 14 | Fidelity Small Cap Index | 633.43K (1.21%) | -6.51K Decreased by -1.03% | May 31, 25 |
| 15 | Fidelity® Small Cap Index | 588.71K (1.12%) | 17.84K Increased by +3.03% | Oct 31, 23 |
| 16 | Federated Hermes MDT SCC Institutional | 550.65K (1.05%) | -86.61K Decreased by -15.73% | Dec 31, 23 |
| 17 | T. Rowe Price Instl Small-Cap Stock | 523.38K (1.00%) | 113.70K Increased by +21.72% | Dec 31, 23 |
| 18 | JPMorgan Small Cap Value I | 510.51K (0.97%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 19 | State St Russell Sm/Mid Cp® Indx NL Cl C | 476.20K (0.91%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 20 | State St Russell Sm/Mid Cp® Indx SL Cl I | 476.20K (0.91%) | 0.00 Increased by 0.00% | May 31, 25 |