| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Baker Bros Advisors LP | 2.14M (16.59%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 2 | RTW INVESTMENTS, LLC | 1.99M (15.45%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 3 | venBio Select Advisor LLC | 1.82M (14.09%) | 10.68K Increased by +0.59% | Mar 31, 26 |
| 4 | Vanguard Group Inc | 1.81M (14.02%) | -3.16K Decreased by -0.17% | Dec 31, 25 |
| 5 | BlackRock Inc | 1.64M (12.74%) | 85.04K Increased by +5.17% | Dec 31, 25 |
| 6 | HHG PLC | 1.58M (12.28%) | -257.85K Decreased by -16.27% | Dec 31, 25 |
| 7 | Paulson & Company Inc | 1.39M (10.79%) | -315.33K Decreased by -22.65% | Mar 31, 26 |
| 8 | State Street Corporation | 624.94K (4.84%) | -75.80K Decreased by -12.13% | Mar 31, 24 |
| 9 | State Street Corp | 583.00K (4.52%) | -75.09K Decreased by -12.88% | Dec 31, 25 |
| 10 | UBS Group AG | 505.71K (3.92%) | 184.21K Increased by +36.43% | Jun 30, 25 |
| 11 | Wellington Management Company LLP | 461.40K (3.58%) | 56.95K Increased by +12.34% | Dec 31, 25 |
| 12 | Geode Capital Management, LLC | 451.74K (3.50%) | 5.51K Increased by +1.22% | Dec 31, 25 |
| 13 | FMR Inc | 439.40K (3.40%) | 38.26K Increased by +8.71% | Dec 31, 25 |
| 14 | Bank of America Corp | 416.02K (3.22%) | 171.73K Increased by +41.28% | Dec 31, 25 |
| 15 | Marshall Wace Asset Management Ltd | 395.40K (3.06%) | -65.25K Decreased by -16.50% | Sep 30, 23 |
| 16 | Holocene Advisors, LP | 390.55K (3.03%) | 390.55K Increased by +100.00% | Mar 31, 25 |
| 17 | Adage Capital Partners Gp LLC | 376.16K (2.91%) | 184.55K Increased by +49.06% | Jun 30, 25 |
| 18 | William Blair Investment Management, LLC | 354.22K (2.74%) | -57.58K Decreased by -16.26% | Dec 31, 25 |
| 19 | AllianceBernstein L.P. | 339.75K (2.63%) | -21.22K Decreased by -6.25% | Dec 31, 23 |
| 20 | Amvescap Plc. | 329.52K (2.55%) | -35.80K Decreased by -10.86% | Mar 31, 26 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 586.52K (4.54%) | 9.77K Increased by +1.67% | Mar 31, 26 |
| 2 | Vanguard US Total Market Shares ETF | 578.31K (4.48%) | 388.00 Increased by +0.07% | Sep 30, 24 |
| 3 | Vanguard Health Care Inv | 444.14K (3.44%) | 202.94K Increased by +45.69% | Mar 31, 26 |
| 4 | Janus Concentrated Growth CF | 429.42K (3.33%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 5 | Janus Henderson Forty S | 429.42K (3.33%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 6 | Vanguard Small Cap Index | 423.74K (3.28%) | 11.08K Increased by +2.62% | Mar 31, 26 |
| 7 | iShares Russell 2000 ETF | 402.28K (3.12%) | 3.38K Increased by +0.84% | Apr 30, 26 |
| 8 | Janus Henderson Opportunistic Alpha MA | 319.65K (2.48%) | 319.62K Increased by +99.99% | Jun 30, 24 |
| 9 | SPDR® S&P Biotech ETF | 299.46K (2.32%) | 670.00 Increased by +0.22% | Aug 31, 25 |
| 10 | Polar Capital Biotech S Inc | 273.15K (2.12%) | 18.15K Increased by +6.65% | Mar 31, 26 |
| 11 | Vanguard Small Cap Growth Index Inv | 237.20K (1.84%) | 122.56K Increased by +51.67% | Mar 31, 26 |
| 12 | Janus Inst Mid Cap Growth CF | 233.27K (1.81%) | 233.27K Increased by +100.00% | Mar 31, 26 |
| 13 | Janus Henderson Research D | 226.92K (1.76%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 14 | Janus Henderson US Research Growth Eq | 226.92K (1.76%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 15 | Janus Selection Global Life Science AUSD | 225.04K (1.74%) | -19.20K Decreased by -8.53% | Mar 31, 24 |
| 16 | T. Rowe Price Health Sciences | 219.75K (1.70%) | -30.45K Decreased by -13.86% | Sep 30, 24 |
| 17 | State Street® SPDR® S&P® Biotech ETF | 219.44K (1.70%) | -1.57K Decreased by -0.71% | Apr 30, 26 |
| 18 | RTW Biotech Opportunities Ord | 213.44K (1.65%) | -1.38K Decreased by -0.65% | Jun 30, 25 |
| 19 | Vanguard Institutional Extnd Mkt Idx Tr | 208.21K (1.61%) | 5.25K Increased by +2.52% | Mar 31, 26 |
| 20 | Artisan International Small-Mid Investor | 198.71K (1.54%) | -15.54K Decreased by -7.82% | Sep 30, 24 |