| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | HHG PLC | 2.21M (19.45%) | -269.77K Decreased by -12.22% | Dec 31, 24 |
| 2 | Paulson & Company Inc | 2.04M (17.98%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 3 | venBio Select Advisor LLC | 2.03M (17.87%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 4 | RTW INVESTMENTS, LLC | 1.99M (17.56%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 5 | Baker Bros Advisors LP | 1.97M (17.39%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 6 | Vanguard Group Inc | 1.71M (15.02%) | -127.63K Decreased by -7.48% | Dec 31, 24 |
| 7 | BlackRock Inc | 1.49M (13.16%) | 32.78K Increased by +2.19% | Dec 31, 24 |
| 8 | FMR Inc | 867.85K (7.64%) | 84.31K Increased by +9.71% | Dec 31, 24 |
| 9 | State Street Corp | 781.29K (6.88%) | -106.46K Decreased by -13.63% | Dec 31, 24 |
| 10 | State Street Corporation | 624.94K (5.50%) | -75.80K Decreased by -12.13% | Mar 31, 24 |
| 11 | T. Rowe Price Associates, Inc. | 588.76K (5.18%) | -144.93K Decreased by -24.62% | Dec 31, 24 |
| 12 | Geode Capital Management, LLC | 410.58K (3.62%) | 4.92K Increased by +1.20% | Dec 31, 24 |
| 13 | Marshall Wace Asset Management Ltd | 395.40K (3.48%) | -65.25K Decreased by -16.50% | Sep 30, 23 |
| 14 | William Blair Investment Management, LLC | 371.77K (3.27%) | 371.77K Increased by +100.00% | Dec 31, 24 |
| 15 | AllianceBernstein L.P. | 339.75K (2.99%) | -21.22K Decreased by -6.25% | Dec 31, 23 |
| 16 | UBS Group AG | 325.27K (2.86%) | 144.64K Increased by +44.47% | Dec 31, 24 |
| 17 | Woodline Partners LP | 309.12K (2.72%) | 162.03K Increased by +52.42% | Dec 31, 24 |
| 18 | Citadel Advisors Llc | 276.83K (2.44%) | 192.92K Increased by +69.69% | Sep 30, 23 |
| 19 | Rock Springs Capital Management LP | 265.21K (2.34%) | 2.15K Increased by +0.81% | Dec 31, 24 |
| 20 | Perceptive Advisors LLC | 264.60K (2.33%) | -165.35K Decreased by -62.49% | Jun 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Janus Concentrated Growth CF | 632.30K (5.57%) | 66.37K Increased by +10.50% | Dec 31, 24 |
| 2 | Janus Henderson Forty S | 632.30K (5.57%) | 0.00 Increased by 0.00% | Jan 31, 25 |
| 3 | Vanguard Total Stock Mkt Idx Inv | 517.04K (4.55%) | 297.00 Increased by +0.06% | Feb 28, 25 |
| 4 | iShares Russell 2000 ETF | 472.62K (4.16%) | -4.07K Decreased by -0.86% | Mar 31, 25 |
| 5 | Vanguard Small Cap Index | 417.65K (3.68%) | 336.00 Increased by +0.08% | Feb 28, 25 |
| 6 | SPDR® S&P Biotech ETF | 366.35K (3.23%) | -3.92K Decreased by -1.07% | Mar 31, 25 |
| 7 | Janus Henderson Contrarian D | 357.90K (3.15%) | 38.25K Increased by +10.69% | Jan 31, 25 |
| 8 | Janus Henderson Opportunistic Alpha MA | 319.65K (2.81%) | 319.62K Increased by +99.99% | Jun 30, 24 |
| 9 | Janus Henderson US Opportunistic Alpha | 319.65K (2.81%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 10 | Vanguard Small Cap Value Index Inv | 275.19K (2.42%) | -885.00 Decreased by -0.32% | Feb 28, 25 |
| 11 | Vanguard Institutional Extnd Mkt Idx Tr | 259.28K (2.28%) | 352.00 Increased by +0.14% | Feb 28, 25 |
| 12 | Janus Henderson Research D | 226.92K (2.00%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 13 | Janus Henderson US Research Growth Eq | 226.92K (2.00%) | 0.00 Increased by 0.00% | Dec 31, 23 |
| 14 | Janus Selection Global Life Science AUSD | 225.04K (1.98%) | -19.20K Decreased by -8.53% | Mar 31, 24 |
| 15 | T. Rowe Price Health Sciences | 219.75K (1.94%) | -30.45K Decreased by -13.86% | Sep 30, 24 |
| 16 | Janus Henderson Glb Life Scn I2 USD | 204.21K (1.80%) | 16.24K Increased by +7.95% | Oct 31, 24 |
| 17 | Artisan International Small-Mid Investor | 198.71K (1.75%) | -15.54K Decreased by -7.82% | Sep 30, 24 |
| 18 | Artisan Non-U.S. Small-Mid Growth Comp | 198.71K (1.75%) | -15.54K Decreased by -7.82% | Sep 30, 24 |
| 19 | US Small-Cap Growth II Equity Comp | 197.64K (1.74%) | -13.38K Decreased by -6.77% | Dec 31, 24 |
| 20 | Janus Henderson Global Life Sciences | 189.99K (1.67%) | -62.41K Decreased by -32.85% | Dec 31, 24 |