| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Frazier Life Sciences Management, L.P. | 4.57M (12.26%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 2 | TRV GP IV, LLC | 4.47M (12.01%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 3 | ARCH VENTURE CORP | 4.12M (11.06%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 4 | Deep Track Capital, LP | 3.48M (9.34%) | -768.88K Decreased by -22.11% | Mar 31, 26 |
| 5 | HHG PLC | 2.86M (7.67%) | -283.71K Decreased by -9.92% | Mar 31, 26 |
| 6 | Paradigm Biocapital Advisors LP | 2.74M (7.37%) | 2.74M Increased by +100.00% | Mar 31, 26 |
| 7 | BlackRock Inc | 2.57M (6.90%) | 283.27K Increased by +11.02% | Mar 31, 26 |
| 8 | Vanguard Group Inc | 1.70M (4.56%) | 362.06K Increased by +21.34% | Dec 31, 25 |
| 9 | VR Adviser, LLC | 1.60M (4.30%) | 53.47K Increased by +3.34% | Mar 31, 26 |
| 10 | Vanguard Capital Management, LLC | 1.44M (3.85%) | 1.44M Increased by +100.00% | Mar 31, 26 |
| 11 | Alphabet Inc | 1.39M (3.73%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 12 | Logos Global Management LP | 1.24M (3.32%) | 285.00K Increased by +23.08% | Mar 31, 26 |
| 13 | Adage Capital Partners Gp LLC | 1.18M (3.16%) | 1.18M Increased by +100.00% | Mar 31, 26 |
| 14 | General Catalyst Group Management, LLC | 1.04M (2.78%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 15 | TRV GP V, LLC | 950.80K (2.55%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 16 | FMR Inc | 864.21K (2.32%) | 135.61K Increased by +15.69% | Mar 31, 26 |
| 17 | Citadel Advisors Llc | 775.71K (2.08%) | 327.50K Increased by +42.22% | Mar 31, 26 |
| 18 | ArrowMark Colorado Holdings, LLC (ArrowMark Partners) | 767.38K (2.06%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 19 | Casdin Capital, LLC | 758.86K (2.04%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 20 | Cormorant Asset Management, LLC | 750.00K (2.01%) | 750.00K Increased by +100.00% | Mar 31, 26 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 1.16M (3.12%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 2 | Fidelity Select Biotechnology | 739.66K (1.99%) | 427.77K Increased by +57.83% | Apr 30, 26 |
| 3 | iShares Russell 2000 ETF | 634.98K (1.70%) | 5.88K Increased by +0.93% | May 29, 26 |
| 4 | Janus Henderson Hrzn Biotec E2 USD | 514.40K (1.38%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 5 | JPMorgan Small Cap Growth A | 433.13K (1.16%) | 433.13K Increased by +100.00% | Apr 30, 26 |
| 6 | Eventide Healthcare & Life Sciences I | 324.04K (0.87%) | 324.04K Increased by +100.00% | Dec 31, 25 |
| 7 | T. Rowe Price Small-Cap Stock | 295.57K (0.79%) | 295.57K Increased by +100.00% | Apr 30, 26 |
| 8 | Fidelity Small Cap Index | 259.43K (0.70%) | 49.52K Increased by +19.09% | Mar 31, 26 |
| 9 | Vanguard Institutional Extnd Mkt Idx Tr | 239.07K (0.64%) | 3.98K Increased by +1.66% | Apr 30, 26 |
| 10 | iShares Biotechnology ETF | 232.78K (0.62%) | 4.46K Increased by +1.92% | May 29, 26 |
| 11 | T. Rowe Price Small-Cap Value | 232.75K (0.62%) | 232.75K Increased by +100.00% | Apr 30, 26 |
| 12 | iShares Russell 2000 Value ETF | 215.77K (0.58%) | 0.00 Increased by 0.00% | May 29, 26 |
| 13 | BlackRock Health Sciences Opps Inv A | 184.45K (0.50%) | 0.00 Increased by 0.00% | Apr 30, 26 |
| 14 | BGF World Healthscience A2 | 175.96K (0.47%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 15 | Heptagon Driehaus US Micro Cap Eq C$ Acc | 161.68K (0.43%) | 53.68K Increased by +33.20% | Apr 30, 26 |
| 16 | MEDICAL BioHealth EUR Acc | 158.65K (0.43%) | 98.00 Increased by +0.06% | Apr 30, 26 |
| 17 | T. Rowe Price Instl Small-Cap Stock | 158.41K (0.43%) | 158.41K Increased by +100.00% | Apr 30, 26 |
| 18 | Fidelity Small Cap Growth | 156.28K (0.42%) | 156.28K Increased by +100.00% | Mar 31, 26 |
| 19 | State St Russell Sm/Mid Cp® Indx SL Cl I | 156.11K (0.42%) | 0.00 Increased by 0.00% | May 31, 26 |
| 20 | Fidelity Growth Compy Commingled Pl S | 141.06K (0.38%) | 88.00 Increased by +0.06% | Apr 30, 26 |