| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 9.47M (14.75%) | 1.29M Increased by +13.65% | Jun 30, 25 |
| 2 | Suvretta Capital Management, LLC | 8.12M (12.64%) | 676.74K Increased by +8.34% | Jun 30, 25 |
| 3 | Bvf Inc | 7.75M (12.08%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 4 | Armistice Capital, LLC | 6.20M (9.66%) | -372.00K Decreased by -6.00% | Jun 30, 25 |
| 5 | Deerfield Management Co | 5.41M (8.43%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 6 | Vanguard Group Inc | 5.35M (8.33%) | 400.09K Increased by +7.48% | Jun 30, 25 |
| 7 | Paradigm Biocapital Advisors LP | 4.33M (6.75%) | -208.06K Decreased by -4.80% | Sep 30, 24 |
| 8 | EcoR1 Capital, LLC | 4.20M (6.54%) | 1.56M Increased by +37.14% | Jun 30, 25 |
| 9 | State Street Corporation | 4.20M (6.54%) | 1.28M Increased by +30.43% | Mar 31, 24 |
| 10 | RA Capital Management, LLC | 4.00M (6.24%) | -446.43K Decreased by -11.15% | Mar 31, 25 |
| 11 | Prosight Management, LP | 3.18M (4.95%) | 1.10M Increased by +34.67% | Jun 30, 25 |
| 12 | State Street Corp | 3.04M (4.73%) | -245.22K Decreased by -8.07% | Jun 30, 25 |
| 13 | Holocene Advisors, LP | 2.69M (4.19%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 14 | Millennium Management LLC | 2.62M (4.08%) | 811.98K Increased by +30.97% | Jun 30, 25 |
| 15 | venBio Select Advisor LLC | 2.25M (3.50%) | -1.29M Decreased by -57.40% | Dec 31, 24 |
| 16 | Geode Capital Management, LLC | 2.01M (3.14%) | 211.47K Increased by +10.50% | Jun 30, 25 |
| 17 | Morgan Stanley - Brokerage Accounts | 1.98M (3.09%) | 60.88K Increased by +3.07% | Jun 30, 25 |
| 18 | Deep Track Capital, LP | 1.96M (3.06%) | 1.58M Increased by +80.40% | Sep 30, 24 |
| 19 | Qube Research & Technologies | 1.91M (2.98%) | 738.76K Increased by +38.64% | Jun 30, 25 |
| 20 | Artal Group S A | 1.82M (2.83%) | -100.00K Decreased by -5.49% | Jun 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 2.69M (4.19%) | -59.74K Decreased by -2.22% | Jul 31, 25 |
| 2 | Vanguard US Total Market Shares ETF | 2.17M (3.37%) | 3.54K Increased by +0.16% | Sep 30, 24 |
| 3 | iShares Russell 2000 ETF | 1.89M (2.94%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 4 | SPDR® S&P Biotech ETF | 1.28M (1.99%) | 2.86K Increased by +0.22% | Aug 31, 25 |
| 5 | HBM Healthcare Investments AG Ord | 1.21M (1.88%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 6 | Vanguard Institutional Extnd Mkt Idx Tr | 974.31K (1.52%) | -440.17K Decreased by -45.18% | Jul 31, 25 |
| 7 | Invesco MSCI World ETF | 897.58K (1.40%) | 897.58K Increased by +100.00% | Jul 31, 25 |
| 8 | Fidelity Small Cap Index | 793.04K (1.24%) | 44.84K Increased by +5.65% | Jun 30, 25 |
| 9 | BlackRock Advantage Small Cap Core Instl | 769.61K (1.20%) | 125.68K Increased by +16.33% | Jul 31, 25 |
| 10 | iShares Russell 2000 Value ETF | 703.32K (1.10%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 11 | Fidelity® Small Cap Index | 680.34K (1.06%) | 20.18K Increased by +2.97% | Oct 31, 23 |
| 12 | iShares Russell 2000 Growth ETF | 637.90K (0.99%) | 0.00 Increased by 0.00% | May 31, 25 |
| 13 | iShares Biotechnology ETF | 494.39K (0.77%) | 0.00 Increased by 0.00% | Aug 31, 25 |
| 14 | Candriam Eqs L Biotech C USD Cap | 467.46K (0.73%) | 0.00 Increased by 0.00% | Oct 31, 24 |
| 15 | Fidelity Extended Market Index | 466.82K (0.73%) | -3.84K Decreased by -0.82% | Jul 31, 25 |
| 16 | Candriam Global Equities Oncology | 439.00K (0.68%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 17 | State St Russell Sm/Mid Cp® Indx NL Cl C | 427.93K (0.67%) | 2.13K Increased by +0.50% | Apr 30, 25 |
| 18 | State St Russell Sm/Mid Cp® Indx SL Cl I | 427.93K (0.67%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 19 | Belfius Equities Cure C Cap | 422.63K (0.66%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 20 | Fidelity® Extended Market Index | 420.95K (0.66%) | 0.00 Increased by 0.00% | Nov 30, 23 |