| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 7.93M (13.27%) | 778.69K Increased by +9.81% | Dec 31, 24 |
| 2 | Armistice Capital, LLC | 5.80M (9.70%) | 3.14M Increased by +54.17% | Dec 31, 24 |
| 3 | Deerfield Management Co | 5.41M (9.05%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 4 | Suvretta Capital Management, LLC | 5.08M (8.49%) | -2.58M Decreased by -50.75% | Dec 31, 24 |
| 5 | Vanguard Group Inc | 4.82M (8.06%) | 615.21K Increased by +12.77% | Dec 31, 24 |
| 6 | RA Capital Management, LLC | 4.45M (7.45%) | 4.45M Increased by +100.00% | Dec 31, 24 |
| 7 | Paradigm Biocapital Advisors LP | 4.33M (7.25%) | -208.06K Decreased by -4.80% | Sep 30, 24 |
| 8 | State Street Corporation | 4.20M (7.03%) | 1.28M Increased by +30.43% | Mar 31, 24 |
| 9 | EcoR1 Capital, LLC | 3.56M (5.95%) | -2.25M Decreased by -63.24% | Dec 31, 24 |
| 10 | State Street Corp | 3.35M (5.60%) | 676.62K Increased by +20.22% | Dec 31, 24 |
| 11 | Morgan Stanley - Brokerage Accounts | 3.27M (5.48%) | 2.07M Increased by +63.14% | Dec 31, 24 |
| 12 | Holocene Advisors, LP | 2.69M (4.50%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 13 | Bvf Inc | 2.57M (4.30%) | -804.29K Decreased by -31.33% | Dec 31, 24 |
| 14 | Millennium Management LLC | 2.37M (3.96%) | 1.52M Increased by +64.29% | Dec 31, 24 |
| 15 | venBio Select Advisor LLC | 2.25M (3.76%) | -1.29M Decreased by -57.40% | Dec 31, 24 |
| 16 | Deep Track Capital, LP | 1.96M (3.29%) | 1.58M Increased by +80.40% | Sep 30, 24 |
| 17 | Artal Group S A | 1.82M (3.04%) | -100.00K Decreased by -5.49% | Jun 30, 24 |
| 18 | COMMODORE CAPITAL LP | 1.80M (3.01%) | 206.65K Increased by +11.48% | Sep 30, 24 |
| 19 | Geode Capital Management, LLC | 1.78M (2.98%) | 1.53K Increased by +0.09% | Dec 31, 24 |
| 20 | Foresite Capital Management IV, LLC | 1.73M (2.89%) | -123.06K Decreased by -7.13% | Dec 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 2.75M (4.61%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 2 | iShares Russell 2000 ETF | 1.95M (3.26%) | -16.89K Decreased by -0.87% | Mar 31, 25 |
| 3 | SPDR® S&P Biotech ETF | 1.61M (2.69%) | -17.20K Decreased by -1.07% | Mar 31, 25 |
| 4 | Vanguard Institutional Extnd Mkt Idx Tr | 1.23M (2.05%) | 2.21K Increased by +0.18% | Feb 28, 25 |
| 5 | HBM Healthcare Investments AG Ord | 1.21M (2.02%) | 710.00K Increased by +58.68% | Dec 31, 24 |
| 6 | Fidelity Small Cap Index | 709.18K (1.19%) | -13.28K Decreased by -1.87% | Jan 31, 25 |
| 7 | Franklin Small Cap Growth SMA | 686.10K (1.15%) | 686.07K Increased by +100.00% | Mar 31, 24 |
| 8 | Fidelity® Small Cap Index | 680.34K (1.14%) | 20.18K Increased by +2.97% | Oct 31, 23 |
| 9 | iShares Russell 2000 Growth ETF | 655.84K (1.10%) | -3.12K Decreased by -0.48% | Mar 31, 25 |
| 10 | iShares Russell 2000 Value ETF | 641.54K (1.07%) | 0.00 Increased by 0.00% | May 29, 24 |
| 11 | Franklin US Small Cap Growth Equity | 621.52K (1.04%) | -57.60K Decreased by -9.27% | Dec 31, 24 |
| 12 | Franklin Biotechnology Discv A(acc)USD | 533.90K (0.89%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 13 | Franklin Small Cap Growth Adv | 486.82K (0.81%) | -134.70K Decreased by -27.67% | Feb 28, 25 |
| 14 | Candriam Eqs L Biotech C USD Cap | 467.46K (0.78%) | 0.00 Increased by 0.00% | Oct 31, 24 |
| 15 | iShares Biotechnology ETF | 462.29K (0.77%) | -5.15K Decreased by -1.11% | Mar 31, 25 |
| 16 | State St Russell Sm/Mid Cp® Indx NL Cl C | 445.39K (0.75%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 17 | Candriam Global Equities Oncology | 439.00K (0.73%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 18 | Belfius Equities Cure C Cap | 422.63K (0.71%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 19 | Fidelity Extended Market Index | 421.83K (0.71%) | -2.69K Decreased by -0.64% | Feb 28, 25 |
| 20 | Fidelity® Extended Market Index | 420.95K (0.70%) | 0.00 Increased by 0.00% | Nov 30, 23 |