| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 8.18M (12.75%) | 243.54K Increased by +2.98% | Mar 31, 25 |
| 2 | Bvf Inc | 7.75M (12.09%) | 5.19M Increased by +66.89% | Mar 31, 25 |
| 3 | Suvretta Capital Management, LLC | 7.44M (11.60%) | 2.36M Increased by +31.76% | Mar 31, 25 |
| 4 | Armistice Capital, LLC | 6.57M (10.25%) | 772.00K Increased by +11.75% | Mar 31, 25 |
| 5 | Deerfield Management Co | 5.41M (8.44%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 6 | Vanguard Group Inc | 4.95M (7.72%) | 129.34K Increased by +2.61% | Mar 31, 25 |
| 7 | Paradigm Biocapital Advisors LP | 4.33M (6.76%) | -208.06K Decreased by -4.80% | Sep 30, 24 |
| 8 | State Street Corporation | 4.20M (6.55%) | 1.28M Increased by +30.43% | Mar 31, 24 |
| 9 | RA Capital Management, LLC | 4.00M (6.25%) | -446.43K Decreased by -11.15% | Mar 31, 25 |
| 10 | State Street Corp | 3.28M (5.12%) | -63.38K Decreased by -1.93% | Mar 31, 25 |
| 11 | Holocene Advisors, LP | 2.69M (4.19%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 12 | EcoR1 Capital, LLC | 2.64M (4.12%) | -916.97K Decreased by -34.73% | Mar 31, 25 |
| 13 | venBio Select Advisor LLC | 2.25M (3.51%) | -1.29M Decreased by -57.40% | Dec 31, 24 |
| 14 | Prosight Management, LP | 2.08M (3.24%) | 753.32K Increased by +36.25% | Mar 31, 25 |
| 15 | Deep Track Capital, LP | 1.96M (3.06%) | 1.58M Increased by +80.40% | Sep 30, 24 |
| 16 | Morgan Stanley - Brokerage Accounts | 1.92M (3.00%) | -1.35M Decreased by -70.25% | Mar 31, 25 |
| 17 | Artal Group S A | 1.82M (2.84%) | -100.00K Decreased by -5.49% | Jun 30, 24 |
| 18 | Millennium Management LLC | 1.81M (2.82%) | -557.61K Decreased by -30.81% | Mar 31, 25 |
| 19 | Geode Capital Management, LLC | 1.80M (2.81%) | 20.52K Increased by +1.14% | Mar 31, 25 |
| 20 | COMMODORE CAPITAL LP | 1.80M (2.81%) | 206.65K Increased by +11.48% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 2.75M (4.29%) | 0.00 Increased by 0.00% | May 31, 25 |
| 2 | Vanguard US Total Market Shares ETF | 2.17M (3.38%) | 3.54K Increased by +0.16% | Sep 30, 24 |
| 3 | iShares Russell 2000 ETF | 1.97M (3.08%) | 13.69K Increased by +0.69% | Jun 30, 25 |
| 4 | SPDR® S&P Biotech ETF | 1.28M (2.00%) | -20.98K Decreased by -1.63% | Jun 30, 25 |
| 5 | Vanguard Institutional Extnd Mkt Idx Tr | 1.28M (2.00%) | 13.22K Increased by +1.03% | May 31, 25 |
| 6 | HBM Healthcare Investments AG Ord | 1.21M (1.89%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 7 | Fidelity Small Cap Index | 760.17K (1.19%) | 23.86K Increased by +3.14% | Apr 30, 25 |
| 8 | iShares Russell 2000 Value ETF | 703.11K (1.10%) | 2.53K Increased by +0.36% | Jun 30, 25 |
| 9 | Fidelity® Small Cap Index | 680.34K (1.06%) | 20.18K Increased by +2.97% | Oct 31, 23 |
| 10 | BlackRock Advantage Small Cap Core Instl | 643.93K (1.00%) | 198.46K Increased by +30.82% | Jun 30, 25 |
| 11 | iShares Russell 2000 Growth ETF | 637.90K (0.99%) | 0.00 Increased by 0.00% | May 31, 25 |
| 12 | iShares Biotechnology ETF | 508.04K (0.79%) | -1.83K Decreased by -0.36% | Jun 30, 25 |
| 13 | Candriam Eqs L Biotech C USD Cap | 467.46K (0.73%) | 0.00 Increased by 0.00% | Oct 31, 24 |
| 14 | Candriam Global Equities Oncology | 439.00K (0.68%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 15 | State St Russell Sm/Mid Cp® Indx NL Cl C | 427.93K (0.67%) | 2.13K Increased by +0.50% | Apr 30, 25 |
| 16 | State St Russell Sm/Mid Cp® Indx SL Cl I | 427.93K (0.67%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 17 | Fidelity Extended Market Index | 423.87K (0.66%) | -1.90K Decreased by -0.45% | May 31, 25 |
| 18 | Belfius Equities Cure C Cap | 422.63K (0.66%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 19 | Fidelity® Extended Market Index | 420.95K (0.66%) | 0.00 Increased by 0.00% | Nov 30, 23 |
| 20 | Schwab US Small-Cap ETF™ | 407.57K (0.64%) | -174.00 Decreased by -0.04% | Jun 28, 25 |