| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Suvretta Capital Management, LLC | 7.65M (15.24%) | 583.15K Increased by +7.62% | Sep 30, 24 |
| 2 | BlackRock Inc | 7.16M (14.25%) | 189.61K Increased by +2.65% | Sep 30, 24 |
| 3 | EcoR1 Capital, LLC | 5.81M (11.56%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 4 | Deerfield Management Co | 5.41M (10.78%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 5 | Paradigm Biocapital Advisors LP | 4.33M (8.63%) | -208.06K Decreased by -4.80% | Sep 30, 24 |
| 6 | Vanguard Group Inc | 4.20M (8.37%) | 163.23K Increased by +3.88% | Sep 30, 24 |
| 7 | State Street Corporation | 4.20M (8.36%) | 1.28M Increased by +30.43% | Mar 31, 24 |
| 8 | venBio Select Advisor LLC | 3.54M (7.05%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 9 | Bvf Inc | 3.37M (6.71%) | -710.28K Decreased by -21.07% | Sep 30, 24 |
| 10 | Holocene Advisors, LP | 2.69M (5.36%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 11 | State Street Corp | 2.67M (5.31%) | -215.70K Decreased by -8.08% | Sep 30, 24 |
| 12 | Armistice Capital, LLC | 2.66M (5.29%) | 308.00K Increased by +11.59% | Sep 30, 24 |
| 13 | Deep Track Capital, LP | 1.96M (3.91%) | 1.58M Increased by +80.40% | Sep 30, 24 |
| 14 | Foresite Capital Management IV, LLC | 1.85M (3.68%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 15 | Artal Group S A | 1.82M (3.62%) | -100.00K Decreased by -5.49% | Jun 30, 24 |
| 16 | COMMODORE CAPITAL LP | 1.80M (3.58%) | 206.65K Increased by +11.48% | Sep 30, 24 |
| 17 | Geode Capital Management, LLC | 1.78M (3.55%) | 41.53K Increased by +2.33% | Sep 30, 24 |
| 18 | Sofinnova Ventures | 1.67M (3.32%) | 1.67M Increased by +100.00% | Dec 31, 23 |
| 19 | Franklin Resources Inc | 1.59M (3.16%) | 23.11K Increased by +1.46% | Sep 30, 24 |
| 20 | TCG Crossover Management, LLC | 1.42M (2.84%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 2.75M (5.48%) | 635.10K Increased by +23.07% | Dec 31, 24 |
| 2 | iShares Russell 2000 ETF | 1.96M (3.91%) | -7.53K Decreased by -0.38% | Dec 31, 24 |
| 3 | SPDR® S&P Biotech ETF | 1.65M (3.28%) | -29.35K Decreased by -1.78% | Dec 31, 24 |
| 4 | Vanguard Institutional Extnd Mkt Idx Tr | 1.22M (2.44%) | 31.25K Increased by +2.55% | Dec 31, 24 |
| 5 | Fidelity Small Cap Index | 742.92K (1.48%) | 4.11K Increased by +0.55% | Oct 31, 24 |
| 6 | Franklin Small Cap Growth SMA | 686.10K (1.37%) | 686.07K Increased by +100.00% | Mar 31, 24 |
| 7 | Fidelity® Small Cap Index | 680.34K (1.35%) | 20.18K Increased by +2.97% | Oct 31, 23 |
| 8 | Franklin US Small Cap Growth Equity | 679.12K (1.35%) | -6.98K Decreased by -1.03% | Sep 30, 24 |
| 9 | iShares Russell 2000 Growth ETF | 667.91K (1.33%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 10 | iShares Russell 2000 Value ETF | 641.54K (1.28%) | 0.00 Increased by 0.00% | May 29, 24 |
| 11 | Franklin Small Cap Growth Adv | 621.52K (1.24%) | 0.00 Increased by 0.00% | Nov 30, 24 |
| 12 | Franklin Biotechnology Discv A(acc)USD | 533.90K (1.06%) | 0.00 Increased by 0.00% | Nov 30, 24 |
| 13 | HBM Healthcare Investments AG Ord | 500.00K (1.00%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 14 | Candriam Eqs L Biotech C USD Cap | 467.46K (0.93%) | 0.00 Increased by 0.00% | Oct 31, 24 |
| 15 | State St Russell Sm/Mid Cp® Indx NL Cl C | 445.39K (0.89%) | -5.90K Decreased by -1.32% | Dec 31, 24 |
| 16 | Candriam Global Equities Oncology | 439.00K (0.87%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 17 | Fidelity Extended Market Index | 423.07K (0.84%) | 9.45K Increased by +2.23% | Nov 30, 24 |
| 18 | Belfius Equities Cure C Cap | 422.63K (0.84%) | -16.37K Decreased by -3.87% | Nov 30, 24 |
| 19 | iShares Biotechnology ETF | 422.06K (0.84%) | -3.04K Decreased by -0.72% | Dec 31, 24 |
| 20 | Fidelity® Extended Market Index | 420.95K (0.84%) | 0.00 Increased by 0.00% | Nov 30, 23 |