| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Baker Bros Advisors LP | 19.92M (50.72%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 2 | BlackRock Inc | 3.95M (10.07%) | 1.00M Increased by +25.34% | Dec 31, 25 |
| 3 | Vanguard Group Inc | 2.31M (5.89%) | 363.10K Increased by +15.70% | Dec 31, 25 |
| 4 | Point72 Asset Management, L.P. | 2.17M (5.52%) | -670.19K Decreased by -30.93% | Dec 31, 25 |
| 5 | BRAIDWELL LP | 2.07M (5.28%) | 2.07M Increased by +100.00% | Dec 31, 25 |
| 6 | State Street Corp | 1.73M (4.41%) | 899.57K Increased by +51.94% | Dec 31, 25 |
| 7 | EcoR1 Capital, LLC | 1.61M (4.11%) | 1.61M Increased by +100.00% | Mar 31, 24 |
| 8 | RTW INVESTMENTS, LLC | 1.49M (3.79%) | 1.00 Increased by +0.00% | Mar 31, 26 |
| 9 | TCG Crossover Management, LLC | 1.45M (3.68%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 10 | The Goldman Sachs Group Inc | 1.30M (3.32%) | 976.25K Increased by +74.92% | Dec 31, 25 |
| 11 | ICONIQ Capital, LLC | 1.27M (3.22%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 12 | T. Rowe Price Associates, Inc. | 1.17M (2.98%) | 667.96K Increased by +57.08% | Dec 31, 25 |
| 13 | Boxer Capital Management, LLC | 1.14M (2.89%) | 386.00K Increased by +33.98% | Dec 31, 25 |
| 14 | SILVERARC CAPITAL MANAGEMENT, LLC | 1.02M (2.60%) | 23.12K Increased by +2.26% | Dec 31, 25 |
| 15 | HHG PLC | 1.00M (2.55%) | 1.00M Increased by +100.00% | Dec 31, 25 |
| 16 | Acadian Asset Management LLC | 969.91K (2.47%) | 949.38K Increased by +97.88% | Sep 30, 25 |
| 17 | Geode Capital Management, LLC | 897.69K (2.29%) | 96.25K Increased by +10.72% | Dec 31, 25 |
| 18 | Adage Capital Partners Gp LLC | 785.00K (2.00%) | -550.00K Decreased by -70.06% | Dec 31, 25 |
| 19 | Renaissance Technologies Corp | 764.14K (1.95%) | 61.54K Increased by +8.05% | Jun 30, 25 |
| 20 | State Street Corporation | 747.50K (1.90%) | 27.06K Increased by +3.62% | Mar 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | State Street® SPDR® S&P® Biotech ETF | 1.50M (3.82%) | -10.67K Decreased by -0.71% | Apr 30, 26 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 1.23M (3.12%) | -26.00 Decreased by -0.00% | Mar 31, 26 |
| 3 | Vanguard US Total Market Shares ETF | 982.01K (2.50%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 4 | iShares Russell 2000 ETF | 892.09K (2.27%) | 7.52K Increased by +0.84% | Apr 30, 26 |
| 5 | BlackRock Advantage Small Cap Core Instl | 523.83K (1.33%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 6 | Vanguard Institutional Extnd Mkt Idx Tr | 449.31K (1.14%) | 18.57K Increased by +4.13% | Mar 31, 26 |
| 7 | iShares Biotechnology ETF | 420.00K (1.07%) | 6.35K Increased by +1.51% | Apr 30, 26 |
| 8 | Artisan International Small-Mid Investor | 407.93K (1.04%) | -108.10K Decreased by -26.50% | Mar 31, 26 |
| 9 | Artisan Non-U.S. Small-Mid Growth Comp | 407.93K (1.04%) | -108.10K Decreased by -26.50% | Mar 31, 26 |
| 10 | iShares Russell 2000 Value ETF | 323.43K (0.82%) | 1.74K Increased by +0.54% | Apr 30, 26 |
| 11 | Fidelity Small Cap Index | 320.39K (0.82%) | 3.23K Increased by +1.01% | Feb 28, 26 |
| 12 | Fidelity® Small Cap Index | 302.77K (0.77%) | 5.66K Increased by +1.87% | Oct 31, 23 |
| 13 | T. Rowe Price New Horizons | 269.64K (0.69%) | 30.04K Increased by +11.14% | Mar 31, 26 |
| 14 | US Small-Cap Growth II Equity Comp | 269.64K (0.69%) | 143.26K Increased by +53.13% | Mar 31, 26 |
| 15 | T. Rowe Price Small-Cap Value | 250.59K (0.64%) | 26.90K Increased by +10.73% | Mar 31, 26 |
| 16 | State St Russell Sm/Mid Cp® Indx SL Cl I | 229.12K (0.58%) | 3.90K Increased by +1.70% | Apr 30, 26 |
| 17 | BGF World Healthscience A2 | 225.29K (0.57%) | 225.29K Increased by +100.00% | Jan 31, 26 |
| 18 | State St Russell Sm/Mid Cp® Indx NL Cl C | 225.22K (0.57%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 19 | Fidelity Extended Market Index | 214.34K (0.55%) | 8.15K Increased by +3.80% | Mar 31, 26 |
| 20 | Federated Hermes MDT SCC Institutional | 210.21K (0.54%) | -34.02K Decreased by -16.18% | Mar 31, 26 |