| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 4.51M (20.41%) | 707.74K Increased by +15.70% | Mar 31, 25 |
| 2 | RA Capital Management, LLC | 3.65M (16.51%) | 1.56M Increased by +42.66% | Mar 31, 25 |
| 3 | Bvf Inc | 3.08M (13.92%) | 750.00K Increased by +24.39% | Mar 31, 25 |
| 4 | Boxer Capital LLC | 2.95M (13.34%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 5 | Mpm Asset Management, LLC | 2.74M (12.40%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 6 | TANG CAPITAL MANAGEMENT LLC | 2.69M (12.17%) | 2.47M Increased by +91.76% | Mar 31, 25 |
| 7 | JPMorgan Chase & Co | 1.98M (8.97%) | -86.13K Decreased by -4.34% | Mar 31, 25 |
| 8 | 683 Capital Management LLC | 1.75M (7.92%) | 831.88K Increased by +47.54% | Mar 31, 25 |
| 9 | MPM Oncology Impact Management LP | 1.75M (7.90%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 10 | Vanguard Group Inc | 1.73M (7.81%) | 92.43K Increased by +5.35% | Mar 31, 25 |
| 11 | EcoR1 Capital, LLC | 1.61M (7.28%) | -1.64M Decreased by -102.03% | Sep 30, 24 |
| 12 | Dimensional Fund Advisors, Inc. | 1.18M (5.35%) | -28.83K Decreased by -2.44% | Mar 31, 25 |
| 13 | Citadel Advisors Llc | 1.18M (5.34%) | -252.54K Decreased by -21.41% | Mar 31, 25 |
| 14 | BRAIDWELL LP | 1.16M (5.26%) | 1.16M Increased by +100.00% | Mar 31, 24 |
| 15 | Boxer Capital Management, LLC | 946.91K (4.29%) | 946.91K Increased by +100.00% | Dec 31, 24 |
| 16 | Vestal Point Capital LP | 900.00K (4.07%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 17 | Citigroup Inc | 853.78K (3.86%) | 833.59K Increased by +97.63% | Dec 31, 24 |
| 18 | Candriam Luxembourg S.C.A. | 769.21K (3.48%) | 259.91K Increased by +33.79% | Sep 30, 24 |
| 19 | Deerfield Management Co | 723.00K (3.27%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 20 | Geode Capital Management, LLC | 650.05K (2.94%) | 5.15K Increased by +0.79% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 1.11M (5.04%) | 153.56K Increased by +13.78% | May 31, 25 |
| 2 | Vanguard US Total Market Shares ETF | 855.64K (3.87%) | -413.20K Decreased by -48.29% | Sep 30, 24 |
| 3 | iShares Russell 2000 ETF | 680.01K (3.08%) | 0.00 Increased by 0.00% | May 31, 25 |
| 4 | BlackRock Advantage Small Cap Core Instl | 599.28K (2.71%) | 0.00 Increased by 0.00% | May 31, 25 |
| 5 | SPDR® S&P Biotech ETF | 546.18K (2.47%) | -16.56K Decreased by -3.03% | Nov 27, 24 |
| 6 | Candriam Eqs L Biotech C USD Cap | 535.59K (2.42%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 7 | Vanguard Institutional Extnd Mkt Idx Tr | 428.06K (1.94%) | 0.00 Increased by 0.00% | May 31, 25 |
| 8 | JPMorgan Small Cap Value I | 374.11K (1.69%) | 9.18K Increased by +2.45% | Apr 30, 25 |
| 9 | CREF Stock R1 | 299.33K (1.35%) | -27.07K Decreased by -9.04% | Feb 28, 25 |
| 10 | DFA US Targeted Value I | 276.97K (1.25%) | 2.28K Increased by +0.82% | Apr 30, 25 |
| 11 | Fidelity Small Cap Index | 259.38K (1.17%) | -8.36K Decreased by -3.22% | Mar 31, 25 |
| 12 | CREF Stock R3 | 243.25K (1.10%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 13 | iShares Russell 2000 Value ETF | 241.46K (1.09%) | 0.00 Increased by 0.00% | May 31, 25 |
| 14 | Fidelity® Small Cap Index | 237.55K (1.08%) | 5.27K Increased by +2.22% | Oct 31, 23 |
| 15 | Belfius Equities Cure C Cap | 233.62K (1.06%) | 0.00 Increased by 0.00% | Oct 31, 24 |
| 16 | Candriam Global Equities Oncology | 233.62K (1.06%) | 148.62K Increased by +63.62% | Sep 30, 24 |
| 17 | Dimensional US Targeted Value ETF | 227.71K (1.03%) | 0.00 Increased by 0.00% | May 30, 25 |
| 18 | JPMorgan US Small Company L | 209.62K (0.95%) | -4.31K Decreased by -2.06% | Apr 30, 25 |
| 19 | Multi-Manager Small Cap Eq Strat Inst | 196.58K (0.89%) | -3.48K Decreased by -1.77% | Apr 30, 25 |
| 20 | iShares Biotechnology ETF | 184.94K (0.84%) | 0.00 Increased by 0.00% | May 31, 25 |