| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | BlackRock Inc | 4.51M (20.30%) | 707.74K Increased by +15.70% | Mar 31, 25 |
| 2 | Bvf Inc | 3.08M (13.85%) | 750.00K Increased by +24.39% | Mar 31, 25 |
| 3 | Boxer Capital LLC | 2.95M (13.27%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 4 | Mpm Asset Management, LLC | 2.74M (12.33%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 5 | TANG CAPITAL MANAGEMENT LLC | 2.69M (12.11%) | 2.47M Increased by +91.76% | Mar 31, 25 |
| 6 | RA Capital Management, LLC | 2.09M (9.42%) | -1.09M Decreased by -52.21% | Dec 31, 24 |
| 7 | JPMorgan Chase & Co | 1.98M (8.93%) | -86.13K Decreased by -4.34% | Mar 31, 25 |
| 8 | 683 Capital Management LLC | 1.75M (7.88%) | 831.88K Increased by +47.54% | Mar 31, 25 |
| 9 | MPM Oncology Impact Management LP | 1.75M (7.86%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 10 | Vanguard Group Inc | 1.73M (7.77%) | 92.43K Increased by +5.35% | Mar 31, 25 |
| 11 | EcoR1 Capital, LLC | 1.61M (7.24%) | -1.64M Decreased by -102.03% | Sep 30, 24 |
| 12 | Citadel Advisors Llc | 1.43M (6.45%) | 196.00K Increased by +13.68% | Dec 31, 24 |
| 13 | Dimensional Fund Advisors, Inc. | 1.18M (5.32%) | -28.83K Decreased by -2.44% | Mar 31, 25 |
| 14 | BRAIDWELL LP | 1.16M (5.23%) | 1.16M Increased by +100.00% | Mar 31, 24 |
| 15 | Boxer Capital Management, LLC | 946.91K (4.26%) | 946.91K Increased by +100.00% | Dec 31, 24 |
| 16 | Vestal Point Capital LP | 900.00K (4.05%) | -125.00K Decreased by -13.89% | Dec 31, 24 |
| 17 | Citigroup Inc | 853.78K (3.84%) | 833.59K Increased by +97.63% | Dec 31, 24 |
| 18 | Candriam Luxembourg S.C.A. | 769.21K (3.46%) | 259.91K Increased by +33.79% | Sep 30, 24 |
| 19 | Deerfield Management Co | 723.00K (3.26%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 20 | Geode Capital Management, LLC | 650.05K (2.93%) | 5.15K Increased by +0.79% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 961.13K (4.33%) | 14.70K Increased by +1.53% | Apr 30, 25 |
| 2 | Vanguard US Total Market Shares ETF | 855.64K (3.85%) | -413.20K Decreased by -48.29% | Sep 30, 24 |
| 3 | iShares Russell 2000 ETF | 671.42K (3.02%) | 113.00 Increased by +0.02% | Apr 30, 25 |
| 4 | BlackRock Advantage Small Cap Core Instl | 599.28K (2.70%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 5 | SPDR® S&P Biotech ETF | 546.18K (2.46%) | -16.56K Decreased by -3.03% | Nov 27, 24 |
| 6 | Candriam Eqs L Biotech C USD Cap | 535.59K (2.41%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 7 | Vanguard Institutional Extnd Mkt Idx Tr | 428.06K (1.93%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 8 | JPMorgan Small Cap Value I | 364.93K (1.64%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 9 | CREF Stock R1 | 299.33K (1.35%) | -27.07K Decreased by -9.04% | Feb 28, 25 |
| 10 | DFA US Targeted Value I | 274.69K (1.24%) | 9.03K Increased by +3.29% | Mar 31, 25 |
| 11 | Fidelity Small Cap Index | 267.73K (1.21%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 12 | iShares Russell 2000 Value ETF | 250.30K (1.13%) | -850.00 Decreased by -0.34% | Apr 30, 25 |
| 13 | CREF Stock R3 | 243.25K (1.10%) | -56.08K Decreased by -23.05% | Mar 31, 25 |
| 14 | Fidelity® Small Cap Index | 237.55K (1.07%) | 5.27K Increased by +2.22% | Oct 31, 23 |
| 15 | Belfius Equities Cure C Cap | 233.62K (1.05%) | 0.00 Increased by 0.00% | Oct 31, 24 |
| 16 | Candriam Global Equities Oncology | 233.62K (1.05%) | 148.62K Increased by +63.62% | Sep 30, 24 |
| 17 | Dimensional US Targeted Value ETF | 227.71K (1.03%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 18 | JPMorgan US Small Company L | 213.93K (0.96%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 19 | iShares Biotechnology ETF | 197.14K (0.89%) | 452.00 Increased by +0.23% | Apr 30, 25 |
| 20 | Multi-Manager Small Cap Eq Strat Inst | 196.58K (0.89%) | -3.48K Decreased by -1.77% | Apr 30, 25 |