| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | EcoR1 Capital, LLC | 10.69M (32.16%) | 10.69M Increased by +100.00% | Jun 30, 25 |
| 2 | BlackRock Inc | 4.51M (13.57%) | 707.74K Increased by +15.70% | Mar 31, 25 |
| 3 | TANG CAPITAL MANAGEMENT LLC | 3.83M (11.51%) | 1.14M Increased by +29.73% | Jun 30, 25 |
| 4 | RA Capital Management, LLC | 3.65M (10.98%) | 1.56M Increased by +42.66% | Mar 31, 25 |
| 5 | Bvf Inc | 3.08M (9.25%) | 750.00K Increased by +24.39% | Mar 31, 25 |
| 6 | Boxer Capital LLC | 2.95M (8.87%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 7 | Mpm Asset Management, LLC | 2.74M (8.24%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 8 | JPMorgan Chase & Co | 1.98M (5.97%) | -86.13K Decreased by -4.34% | Mar 31, 25 |
| 9 | 683 Capital Management LLC | 1.75M (5.27%) | 831.88K Increased by +47.54% | Mar 31, 25 |
| 10 | MPM Oncology Impact Management LP | 1.75M (5.25%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 11 | Vanguard Group Inc | 1.66M (5.01%) | -62.30K Decreased by -3.74% | Jun 30, 25 |
| 12 | Citadel Advisors Llc | 1.18M (3.55%) | -252.54K Decreased by -21.41% | Mar 31, 25 |
| 13 | BRAIDWELL LP | 1.16M (3.50%) | 1.16M Increased by +100.00% | Mar 31, 24 |
| 14 | Boxer Capital Management, LLC | 946.91K (2.85%) | 946.91K Increased by +100.00% | Dec 31, 24 |
| 15 | Vestal Point Capital LP | 900.00K (2.71%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 16 | Citigroup Inc | 853.78K (2.57%) | 833.59K Increased by +97.63% | Dec 31, 24 |
| 17 | Dimensional Fund Advisors, Inc. | 832.76K (2.51%) | -348.49K Decreased by -41.85% | Jun 30, 25 |
| 18 | Candriam Luxembourg S.C.A. | 769.21K (2.31%) | 259.91K Increased by +33.79% | Sep 30, 24 |
| 19 | Deerfield Management Co | 723.00K (2.18%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 20 | Geode Capital Management, LLC | 650.05K (1.96%) | 5.15K Increased by +0.79% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard US Total Market Shares ETF | 855.64K (2.57%) | -413.20K Decreased by -48.29% | Sep 30, 24 |
| 2 | Vanguard Total Stock Mkt Idx Inv | 753.97K (2.27%) | -16.62K Decreased by -2.20% | Jul 31, 25 |
| 3 | iShares Russell 2000 ETF | 700.29K (2.11%) | -13.34K Decreased by -1.90% | Jul 31, 25 |
| 4 | BlackRock Advantage Small Cap Core Instl | 591.43K (1.78%) | -1.75K Decreased by -0.30% | Jul 31, 25 |
| 5 | SPDR® S&P Biotech ETF | 546.18K (1.64%) | -16.56K Decreased by -3.03% | Nov 27, 24 |
| 6 | Candriam Eqs L Biotech C USD Cap | 535.59K (1.61%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 7 | JPMorgan Small Cap Value I | 370.99K (1.12%) | -3.12K Decreased by -0.84% | Jun 30, 25 |
| 8 | Vanguard Institutional Extnd Mkt Idx Tr | 301.38K (0.91%) | -129.10K Decreased by -42.84% | Jul 31, 25 |
| 9 | CREF Stock R1 | 299.33K (0.90%) | -27.07K Decreased by -9.04% | Feb 28, 25 |
| 10 | Fidelity Small Cap Index | 269.17K (0.81%) | -5.46K Decreased by -2.03% | May 31, 25 |
| 11 | iShares Russell 2000 Value ETF | 257.51K (0.77%) | 191.00 Increased by +0.07% | Jul 31, 25 |
| 12 | Fidelity® Small Cap Index | 237.55K (0.71%) | 5.27K Increased by +2.22% | Oct 31, 23 |
| 13 | Belfius Equities Cure C Cap | 233.62K (0.70%) | 0.00 Increased by 0.00% | Oct 31, 24 |
| 14 | Candriam Global Equities Oncology | 233.62K (0.70%) | 148.62K Increased by +63.62% | Sep 30, 24 |
| 15 | iShares Biotechnology ETF | 224.16K (0.67%) | 1.92K Increased by +0.86% | Jul 31, 25 |
| 16 | JPMorgan US Small Company L | 204.88K (0.62%) | -4.74K Decreased by -2.31% | May 31, 25 |
| 17 | Multi-Manager Small Cap Eq Strat Inst | 196.58K (0.59%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 18 | State St Russell Sm/Mid Cp® Indx NL Cl C | 167.50K (0.50%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 19 | State St Russell Sm/Mid Cp® Indx SL Cl I | 167.50K (0.50%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 20 | DFA US Targeted Value I | 164.10K (0.49%) | -99.45K Decreased by -60.60% | Jun 30, 25 |