| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vivo Capital, LLC | 6.17M (16.12%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 2 | Samsara BioCapital, LLC | 3.64M (9.50%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 3 | Novo A/S | 2.51M (6.56%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 4 | Partner Fund Management LP | 1.97M (5.15%) | -369.03K Decreased by -18.71% | Jun 30, 25 |
| 5 | Ikarian Capital, LLC | 1.39M (3.62%) | -139.33K Decreased by -10.05% | Dec 31, 25 |
| 6 | Alyeska Investment Group, L.P. | 987.65K (2.58%) | 987.65K Increased by +100.00% | Sep 30, 23 |
| 7 | Pivotal bioVenture Partners Investment Advisor LLC | 864.20K (2.26%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 8 | Bank of America Corp | 799.95K (2.09%) | -815.12K Decreased by -101.90% | Sep 30, 25 |
| 9 | Morgan Stanley - Brokerage Accounts | 668.40K (1.74%) | 14.72K Increased by +2.20% | Sep 30, 25 |
| 10 | Beacon Pointe Advisors, LLC | 506.00K (1.32%) | 506.00K Increased by +100.00% | Dec 31, 25 |
| 11 | Logos Global Management LP | 493.83K (1.29%) | -493.83K Decreased by -100.00% | Sep 30, 24 |
| 12 | BOOTHBAY FUND MANAGEMENT, LLC | 451.85K (1.18%) | -139.33K Decreased by -30.83% | Dec 31, 25 |
| 13 | Dauntless Investment Group, LLC | 451.64K (1.18%) | 451.64K Increased by +100.00% | Dec 31, 25 |
| 14 | Marshall Wace Asset Management Ltd | 429.34K (1.12%) | -623.29K Decreased by -145.18% | Dec 31, 25 |
| 15 | LANDSCAPE CAPITAL MANAGEMENT,LLC | 347.41K (0.91%) | -52.83K Decreased by -15.21% | Jun 30, 25 |
| 16 | Point72 Asset Management, L.P. | 250.00K (0.65%) | 250.00K Increased by +100.00% | Sep 30, 25 |
| 17 | Renaissance Technologies Corp | 207.60K (0.54%) | -339.71K Decreased by -163.64% | Dec 31, 25 |
| 18 | Soleus Capital Management, L.P. | 192.67K (0.50%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 19 | Millennium Management LLC | 138.72K (0.36%) | -1.25M Decreased by -903.77% | Dec 31, 25 |
| 20 | Sectoral Asset Management Inc | 117.69K (0.31%) | 22.69K Increased by +19.28% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | HBM Healthcare Investments AG Ord | 3.94M (10.30%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 2 | Fidelity Select Biotechnology | 314.60K (0.82%) | 314.60K Increased by +100.00% | Mar 31, 24 |
| 3 | Abante Quant Value FI | 218.78K (0.57%) | 218.78K Increased by +100.00% | Jan 31, 26 |
| 4 | Protea Sectoral Biotech Opps IF USD Acc | 91.44K (0.24%) | 0.00 Increased by 0.00% | May 31, 25 |
| 5 | Bridgeway Ultra-Small Company Market | 75.00K (0.20%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 6 | RIM Global Bioscience EUR | 55.00K (0.14%) | 55.00K Increased by +100.00% | Jan 31, 24 |
| 7 | Fidelity Nasdaq Composite Index | 33.31K (0.09%) | 0.00 Increased by 0.00% | Feb 28, 26 |