| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | FMR Inc | 16.55M (17.55%) | 3.49M Increased by +21.11% | Dec 31, 25 |
| 2 | T. Rowe Price Investment Management,Inc. | 14.64M (15.52%) | 6.22M Increased by +42.49% | Dec 31, 25 |
| 3 | BlackRock Inc | 7.59M (8.05%) | 1.77M Increased by +23.33% | Dec 31, 25 |
| 4 | Point72 Asset Management, L.P. | 7.03M (7.46%) | 2.21M Increased by +31.42% | Dec 31, 25 |
| 5 | Vanguard Group Inc | 6.04M (6.40%) | 1.14M Increased by +18.96% | Dec 31, 25 |
| 6 | Redmile Group, LLC | 5.72M (6.06%) | 695.00K Increased by +12.15% | Dec 31, 25 |
| 7 | Enavate Sciences GP, LLC | 4.77M (5.06%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 8 | PRIMECAP Management Company | 4.69M (4.97%) | 1.67M Increased by +35.59% | Dec 31, 25 |
| 9 | State Street Corp | 3.87M (4.10%) | 1.06M Increased by +27.51% | Dec 31, 25 |
| 10 | Driehaus Capital Management LLC | 3.71M (3.93%) | 3.01M Increased by +81.20% | Dec 31, 25 |
| 11 | Opaleye Management Inc | 3.53M (3.74%) | -20.42K Decreased by -0.58% | Jun 30, 25 |
| 12 | T. Rowe Price Associates, Inc. | 3.38M (3.58%) | -362.53K Decreased by -10.72% | Dec 31, 25 |
| 13 | JPMorgan Chase & Co | 2.86M (3.03%) | 2.79M Increased by +97.72% | Dec 31, 25 |
| 14 | EcoR1 Capital, LLC | 2.86M (3.03%) | -1.22M Decreased by -42.86% | Dec 31, 25 |
| 15 | Geode Capital Management, LLC | 2.36M (2.50%) | 466.81K Increased by +19.77% | Dec 31, 25 |
| 16 | The Toronto-Dominion Bank | 2.09M (2.21%) | 2.09M Increased by +100.00% | Jun 30, 25 |
| 17 | Jefferies Financial Group Inc | 2.00M (2.12%) | -100.00K Decreased by -5.00% | Dec 31, 25 |
| 18 | Readystate Asset Management LP | 1.84M (1.95%) | 524.92K Increased by +28.48% | Dec 31, 25 |
| 19 | Citadel Advisors Llc | 1.74M (1.85%) | 899.57K Increased by +51.68% | Dec 31, 25 |
| 20 | Morgan Stanley - Brokerage Accounts | 1.71M (1.81%) | -124.73K Decreased by -7.30% | Dec 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Fidelity Growth Compy Commingled Pl S | 6.19M (6.56%) | 0.00 Increased by 0.00% | Feb 28, 26 |
| 2 | T. Rowe Price Small-Cap Stock | 5.76M (6.11%) | 476.40K Increased by +8.26% | Mar 31, 26 |
| 3 | T. Rowe Price US Small-Cap Core Equity | 5.76M (6.11%) | 636.97K Increased by +11.05% | Mar 31, 26 |
| 4 | Fidelity Growth Company Fund | 4.74M (5.02%) | 228.20K Increased by +4.82% | Mar 31, 26 |
| 5 | PRIMECAP Odyssey Aggressive Growth | 3.81M (4.04%) | 1.14M Increased by +29.91% | Dec 31, 25 |
| 6 | State Street® SPDR® S&P® Biotech ETF | 3.27M (3.47%) | -32.38K Decreased by -0.99% | Apr 30, 26 |
| 7 | Vanguard Total Stock Mkt Idx Inv | 3.17M (3.36%) | 23.39K Increased by +0.74% | Mar 31, 26 |
| 8 | T. Rowe Price Instl Small-Cap Stock | 3.12M (3.30%) | 228.05K Increased by +7.32% | Mar 31, 26 |
| 9 | T. Rowe Price U.S. SC Core Eq Tr-D | 2.79M (2.96%) | 429.26K Increased by +15.39% | Mar 31, 26 |
| 10 | iShares Russell 2000 ETF | 2.38M (2.53%) | -588.00 Decreased by -0.02% | Apr 29, 26 |
| 11 | Fidelity Select Biotechnology | 2.13M (2.26%) | 0.00 Increased by 0.00% | Mar 31, 26 |
| 12 | Fidelity Growth Compy Commingled Pl O | 1.79M (1.89%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 13 | T. Rowe Price Health Sciences | 1.76M (1.87%) | 20.08K Increased by +1.14% | Mar 31, 26 |
| 14 | Vanguard US Total Market Shares ETF | 1.64M (1.74%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 15 | T. Rowe Price Small-Cap Value | 1.62M (1.72%) | 547.10K Increased by +33.82% | Mar 31, 26 |
| 16 | T. Rowe Price U.S. SC Core Eq Tr-Z | 1.37M (1.46%) | 449.50K Increased by +32.73% | Mar 31, 25 |
| 17 | Fidelity Growth Company K6 | 1.37M (1.45%) | 55.22K Increased by +4.03% | Mar 31, 26 |
| 18 | Fidelity Series Growth Company | 1.24M (1.32%) | 17.80K Increased by +1.43% | Mar 31, 26 |
| 19 | Vanguard Institutional Extnd Mkt Idx Tr | 1.16M (1.23%) | 24.24K Increased by +2.09% | Mar 31, 26 |
| 20 | T. Rowe Price U.S. SC Value Eq Tr-D | 1.08M (1.15%) | 461.13K Increased by +42.56% | Mar 31, 26 |