| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | T. Rowe Price Investment Management,Inc. | 7.07M (18.81%) | 15.84K Increased by +0.22% | Jun 30, 25 |
| 2 | RTW INVESTMENTS, LLC | 4.87M (12.96%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 3 | FMR Inc | 4.84M (12.88%) | 22.80K Increased by +0.47% | Mar 31, 25 |
| 4 | Wellington Management Company LLP | 4.21M (11.21%) | -1.92M Decreased by -45.52% | Jun 30, 25 |
| 5 | PRIMECAP Management Company | 3.77M (10.04%) | 1.09M Increased by +28.98% | Jun 30, 25 |
| 6 | Bellevue Group AG | 2.44M (6.50%) | 1.22M Increased by +49.96% | Jun 30, 25 |
| 7 | Rock Springs Capital Management LP | 2.37M (6.30%) | -293.69K Decreased by -12.40% | Mar 31, 24 |
| 8 | Baker Bros Advisors LP | 2.32M (6.18%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 9 | TANG CAPITAL MANAGEMENT LLC | 2.11M (5.60%) | 189.90K Increased by +9.02% | Jun 30, 25 |
| 10 | Deep Track Capital, LP | 1.80M (4.79%) | 388.60K Increased by +21.59% | Jun 30, 25 |
| 11 | Paradigm Biocapital Advisors LP | 1.79M (4.76%) | 333.29K Increased by +18.65% | Mar 31, 24 |
| 12 | Morgan Stanley - Brokerage Accounts | 1.74M (4.62%) | 135.18K Increased by +7.78% | Jun 30, 24 |
| 13 | General Atlantic Llc | 1.26M (3.36%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 14 | Bvf Inc | 1.02M (2.73%) | 1.02M Increased by +100.00% | Jun 30, 25 |
| 15 | T. Rowe Price Associates, Inc. | 1.01M (2.68%) | -882.35K Decreased by -87.74% | Jun 30, 25 |
| 16 | Kynam Capital Management, LP | 976.27K (2.60%) | -719.31K Decreased by -73.68% | Jun 30, 25 |
| 17 | Logos Global Management LP | 900.00K (2.40%) | 500.00K Increased by +55.56% | Mar 31, 24 |
| 18 | BlackRock Inc | 871.79K (2.32%) | 4.44K Increased by +0.51% | Jun 30, 24 |
| 19 | Point72 Asset Management, L.P. | 820.42K (2.18%) | 192.13K Increased by +23.42% | Jun 30, 25 |
| 20 | Fiera Capital Corporation | 813.07K (2.16%) | 7.92K Increased by +0.97% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Health Care Inv | 3.15M (8.38%) | -1.44M Decreased by -45.62% | Jun 30, 25 |
| 2 | Vanguard Capital Opportunity Inv | 2.44M (6.49%) | 682.68K Increased by +27.99% | Jun 30, 25 |
| 3 | T. Rowe Price Small-Cap Stock | 2.06M (5.48%) | 44.92K Increased by +2.18% | Jun 30, 25 |
| 4 | T. Rowe Price US Small-Cap Core Equity | 2.06M (5.48%) | 195.97K Increased by +9.52% | Jun 30, 25 |
| 5 | Fidelity Growth Compy Commingled Pl S | 1.44M (3.84%) | 8.44K Increased by +0.59% | Jun 30, 25 |
| 6 | BB Biotech AG Ord | 1.21M (3.21%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 7 | Fidelity Growth Compy Commingled Pl O | 1.15M (3.07%) | 101.00 Increased by +0.01% | Aug 31, 24 |
| 8 | PRIMECAP Odyssey Aggressive Growth | 1.11M (2.96%) | 365.18K Increased by +32.79% | Jun 30, 25 |
| 9 | T. Rowe Price Instl Small-Cap Stock | 1.08M (2.87%) | 1.80K Increased by +0.17% | Jun 30, 25 |
| 10 | T. Rowe Price Small-Cap Value | 1.07M (2.86%) | -1.26K Decreased by -0.12% | Jun 30, 25 |
| 11 | Fidelity Growth Company Fund | 1.02M (2.71%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 12 | T. Rowe Price U.S. SC Core Eq Tr-D | 1.01M (2.69%) | 110.07K Increased by +10.87% | Jun 30, 25 |
| 13 | T. Rowe Price U.S. SC Core Eq Tr-Z | 902.33K (2.40%) | 44.96K Increased by +4.98% | Mar 31, 25 |
| 14 | T. Rowe Price Health Sciences | 773.70K (2.06%) | -37.18K Decreased by -4.81% | Jun 30, 25 |
| 15 | T. Rowe Price U.S. SC Value Eq Tr-Z | 737.44K (1.96%) | 20.48K Increased by +2.78% | Mar 31, 25 |
| 16 | Vanguard Explorer Inv | 648.22K (1.73%) | 648.22K Increased by +100.00% | Mar 31, 24 |
| 17 | T. Rowe Price U.S. SC Value Eq Tr-D | 633.25K (1.69%) | -104.18K Decreased by -16.45% | Jun 30, 25 |
| 18 | T. Rowe Price US Smlr Cm Eq A USD | 552.60K (1.47%) | -28.36K Decreased by -5.13% | Apr 30, 25 |
| 19 | T. Rowe Price All-Cap Opportunities Fund | 520.45K (1.39%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 20 | T. Rowe Price US All-Cap Opp Eq Comp | 520.45K (1.39%) | 0.00 Increased by 0.00% | Mar 31, 25 |