| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | T. Rowe Price Investment Management,Inc. | 6.70M (17.92%) | 200.37K Increased by +2.99% | Dec 31, 24 |
| 2 | Wellington Management Company LLP | 6.62M (17.70%) | -431.78K Decreased by -6.53% | Dec 31, 24 |
| 3 | RTW INVESTMENTS, LLC | 4.87M (13.03%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 4 | FMR Inc | 4.82M (12.89%) | -18.34K Decreased by -0.38% | Dec 31, 24 |
| 5 | PRIMECAP Management Company | 2.67M (7.14%) | 196.53K Increased by +7.36% | Dec 31, 24 |
| 6 | Rock Springs Capital Management LP | 2.37M (6.33%) | -293.69K Decreased by -12.40% | Mar 31, 24 |
| 7 | T. Rowe Price Associates, Inc. | 2.19M (5.85%) | 29.83K Increased by +1.36% | Dec 31, 24 |
| 8 | Paradigm Biocapital Advisors LP | 1.79M (4.78%) | 333.29K Increased by +18.65% | Mar 31, 24 |
| 9 | Morgan Stanley - Brokerage Accounts | 1.74M (4.65%) | 135.18K Increased by +7.78% | Jun 30, 24 |
| 10 | TANG CAPITAL MANAGEMENT LLC | 1.56M (4.16%) | 450.00K Increased by +28.93% | Dec 31, 24 |
| 11 | Baker Bros Advisors LP | 1.52M (4.05%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 12 | General Atlantic Llc | 1.26M (3.37%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 13 | Kynam Capital Management, LP | 1.23M (3.28%) | 1.23M Increased by +100.00% | Dec 31, 24 |
| 14 | Bellevue Group AG | 1.21M (3.22%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 15 | Armistice Capital, LLC | 1.20M (3.21%) | -64.00K Decreased by -5.33% | Dec 31, 24 |
| 16 | Logos Global Management LP | 900.00K (2.41%) | 500.00K Increased by +55.56% | Mar 31, 24 |
| 17 | BlackRock Inc | 871.79K (2.33%) | 4.44K Increased by +0.51% | Jun 30, 24 |
| 18 | BRAIDWELL LP | 797.27K (2.13%) | 797.27K Increased by +100.00% | Jun 30, 24 |
| 19 | Fiera Capital Corporation | 779.96K (2.09%) | -65.77K Decreased by -8.43% | Dec 31, 24 |
| 20 | Pictet Asset Manangement SA | 706.61K (1.89%) | -103.00K Decreased by -14.58% | Mar 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Health Care Inv | 4.58M (12.26%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 2 | T. Rowe Price Small-Cap Stock | 1.86M (4.98%) | -402.00 Decreased by -0.02% | Mar 31, 25 |
| 3 | T. Rowe Price US Small-Cap Core Equity | 1.86M (4.98%) | 126.24K Increased by +6.78% | Mar 31, 25 |
| 4 | Vanguard Capital Opportunity Inv | 1.76M (4.70%) | 4.00K Increased by +0.23% | Mar 31, 25 |
| 5 | Fidelity Growth Compy Commingled Pl S | 1.29M (3.45%) | 6.51K Increased by +0.50% | Mar 31, 25 |
| 6 | T. Rowe Price Small-Cap Value | 1.26M (3.36%) | -270.00 Decreased by -0.02% | Mar 31, 25 |
| 7 | BB Biotech AG Ord | 1.21M (3.22%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 8 | Fidelity Growth Compy Commingled Pl O | 1.15M (3.08%) | 101.00 Increased by +0.01% | Aug 31, 24 |
| 9 | T. Rowe Price Instl Small-Cap Stock | 992.50K (2.65%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 10 | T. Rowe Price Health Sciences | 916.57K (2.45%) | -101.42K Decreased by -11.06% | Mar 31, 25 |
| 11 | Fidelity Growth Company Fund | 912.54K (2.44%) | 4.60K Increased by +0.50% | Mar 31, 25 |
| 12 | T. Rowe Price U.S. SC Core Eq Tr-Z | 902.33K (2.41%) | 44.96K Increased by +4.98% | Mar 31, 25 |
| 13 | T. Rowe Price U.S. SC Core Eq Tr-D | 857.37K (2.29%) | -43.79K Decreased by -5.11% | Dec 31, 24 |
| 14 | PRIMECAP Odyssey Aggressive Growth | 748.43K (2.00%) | 5.40K Increased by +0.72% | Mar 31, 25 |
| 15 | T. Rowe Price U.S. SC Value Eq Tr-Z | 737.44K (1.97%) | 20.48K Increased by +2.78% | Mar 31, 25 |
| 16 | T. Rowe Price U.S. SC Value Eq Tr-D | 716.96K (1.92%) | 108.27K Increased by +15.10% | Dec 31, 24 |
| 17 | Vanguard Explorer Inv | 648.22K (1.73%) | 648.22K Increased by +100.00% | Mar 31, 24 |
| 18 | T. Rowe Price US Smlr Cm Eq A USD | 580.96K (1.55%) | -29.77K Decreased by -5.12% | Mar 31, 25 |
| 19 | T. Rowe Price All-Cap Opportunities Fund | 520.45K (1.39%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 20 | T. Rowe Price US All-Cap Opp Eq Comp | 520.45K (1.39%) | 0.00 Increased by 0.00% | Mar 31, 25 |