| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | T. Rowe Price Investment Management,Inc. | 6.70M (17.98%) | 200.37K Increased by +2.99% | Dec 31, 24 |
| 2 | Wellington Management Company LLP | 6.62M (17.76%) | -431.78K Decreased by -6.53% | Dec 31, 24 |
| 3 | RTW INVESTMENTS, LLC | 4.87M (13.07%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 4 | FMR Inc | 4.82M (12.93%) | -18.34K Decreased by -0.38% | Dec 31, 24 |
| 5 | PRIMECAP Management Company | 2.67M (7.16%) | 196.53K Increased by +7.36% | Dec 31, 24 |
| 6 | Rock Springs Capital Management LP | 2.37M (6.35%) | -293.69K Decreased by -12.40% | Mar 31, 24 |
| 7 | T. Rowe Price Associates, Inc. | 2.19M (5.87%) | 29.83K Increased by +1.36% | Dec 31, 24 |
| 8 | Paradigm Biocapital Advisors LP | 1.79M (4.80%) | 333.29K Increased by +18.65% | Mar 31, 24 |
| 9 | Morgan Stanley - Brokerage Accounts | 1.74M (4.66%) | 135.18K Increased by +7.78% | Jun 30, 24 |
| 10 | TANG CAPITAL MANAGEMENT LLC | 1.56M (4.17%) | 450.00K Increased by +28.93% | Dec 31, 24 |
| 11 | Baker Bros Advisors LP | 1.52M (4.07%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 12 | General Atlantic Llc | 1.26M (3.39%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 13 | Kynam Capital Management, LP | 1.23M (3.29%) | 1.23M Increased by +100.00% | Dec 31, 24 |
| 14 | Bellevue Group AG | 1.21M (3.24%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 15 | Armistice Capital, LLC | 1.20M (3.22%) | -64.00K Decreased by -5.33% | Dec 31, 24 |
| 16 | Logos Global Management LP | 900.00K (2.42%) | 500.00K Increased by +55.56% | Mar 31, 24 |
| 17 | BlackRock Inc | 871.79K (2.34%) | 4.44K Increased by +0.51% | Jun 30, 24 |
| 18 | BRAIDWELL LP | 797.27K (2.14%) | 797.27K Increased by +100.00% | Jun 30, 24 |
| 19 | Fiera Capital Corporation | 779.96K (2.09%) | -65.77K Decreased by -8.43% | Dec 31, 24 |
| 20 | Pictet Asset Manangement SA | 706.61K (1.90%) | -103.00K Decreased by -14.58% | Mar 31, 24 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Health Care Inv | 4.58M (12.30%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | T. Rowe Price Small-Cap Stock | 1.86M (5.00%) | 126.59K Increased by +6.80% | Feb 28, 25 |
| 3 | Vanguard Capital Opportunity Inv | 1.75M (4.70%) | 130.33K Increased by +7.44% | Dec 31, 24 |
| 4 | T. Rowe Price US Small-Cap Core Equity | 1.74M (4.66%) | -83.61K Decreased by -4.82% | Dec 31, 24 |
| 5 | Fidelity Growth Compy Commingled Pl S | 1.28M (3.45%) | 13.72K Increased by +1.07% | Feb 28, 25 |
| 6 | T. Rowe Price Small-Cap Value | 1.26M (3.37%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 7 | BB Biotech AG Ord | 1.21M (3.24%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 8 | Fidelity Growth Compy Commingled Pl O | 1.15M (3.09%) | 101.00 Increased by +0.01% | Aug 31, 24 |
| 9 | T. Rowe Price Health Sciences | 1.02M (2.73%) | -22.20K Decreased by -2.18% | Feb 28, 25 |
| 10 | T. Rowe Price Instl Small-Cap Stock | 992.50K (2.66%) | 77.36K Increased by +7.79% | Feb 28, 25 |
| 11 | Fidelity Growth Company Fund | 907.94K (2.44%) | 6.40K Increased by +0.70% | Feb 28, 25 |
| 12 | T. Rowe Price U.S. SC Core Eq Tr-Z | 857.37K (2.30%) | -43.79K Decreased by -5.11% | Dec 31, 24 |
| 13 | PRIMECAP Odyssey Aggressive Growth | 743.03K (1.99%) | 68.60K Increased by +9.23% | Dec 31, 24 |
| 14 | T. Rowe Price U.S. SC Value Eq Tr-Z | 716.96K (1.92%) | 108.27K Increased by +15.10% | Dec 31, 24 |
| 15 | Vanguard Explorer Inv | 648.22K (1.74%) | 648.22K Increased by +100.00% | Mar 31, 24 |
| 16 | T. Rowe Price US Smlr Cm Eq A USD | 610.74K (1.64%) | 22.07K Increased by +3.61% | Feb 28, 25 |
| 17 | T. Rowe Price All-Cap Opportunities Fund | 520.45K (1.40%) | 0.00 Increased by 0.00% | Feb 28, 25 |
| 18 | T. Rowe Price US All-Cap Opp Eq Comp | 520.45K (1.40%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 19 | T. Rowe Price US All-Cap Opp Eq SMA | 520.45K (1.40%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 20 | Fidelity Select Health Care | 513.16K (1.38%) | 1.22K Increased by +0.24% | Feb 28, 25 |