| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Baker Bros Advisors LP | 4.10M (0.21%) | 953.00 Increased by +0.02% | Mar 31, 25 |
| 2 | T. Rowe Price Associates, Inc. | 3.57M (0.18%) | -445.26K Decreased by -12.48% | Dec 31, 24 |
| 3 | Artal Group S A | 3.33M (0.17%) | 250.00K Increased by +7.51% | Jun 30, 24 |
| 4 | Siren, L.L.C. | 3.26M (0.17%) | -74.60K Decreased by -2.29% | Mar 31, 25 |
| 5 | Redmile Group, LLC | 2.95M (0.15%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 6 | Sanofi | 1.44M (0.07%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 7 | BlackRock Inc | 1.03M (0.05%) | -23.50K Decreased by -2.28% | Mar 31, 25 |
| 8 | RA Capital Management, LLC | 937.50K (0.05%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 9 | Vanguard Group Inc | 875.57K (0.04%) | -20.78K Decreased by -2.37% | Mar 31, 25 |
| 10 | Goldman Sachs Group Inc | 793.39K (0.04%) | -185.10K Decreased by -23.33% | Mar 31, 25 |
| 11 | Great Point Partners LLC | 615.32K (0.03%) | 115.32K Increased by +18.74% | Sep 30, 23 |
| 12 | State Street Corp | 493.70K (0.03%) | 34.25K Increased by +6.94% | Mar 31, 25 |
| 13 | FMR Inc | 473.43K (0.02%) | -346.10K Decreased by -73.11% | Dec 31, 24 |
| 14 | ExodusPoint Capital Management, LP | 453.90K (0.02%) | 453.90K Increased by +100.00% | Sep 30, 23 |
| 15 | Geode Capital Management, LLC | 425.66K (0.02%) | 16.53K Increased by +3.88% | Mar 31, 25 |
| 16 | GSA Capital Partners LLP | 425.30K (0.02%) | 331.82K Increased by +78.02% | Mar 31, 25 |
| 17 | Adage Capital Partners Gp LLC | 400.00K (0.02%) | 400.00K Increased by +100.00% | Dec 31, 23 |
| 18 | State Street Corporation | 319.27K (0.02%) | 11.80K Increased by +3.70% | Mar 31, 24 |
| 19 | Opaleye Management Inc | 261.00K (0.01%) | 197.50K Increased by +75.67% | Sep 30, 23 |
| 20 | AQR Capital Management LLC | 238.87K (0.01%) | 238.87K Increased by +100.00% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | T. Rowe Price New Horizons | 1.78M (0.09%) | 0.00 Increased by 0.00% | Dec 31, 24 |
| 2 | US Small-Cap Growth II Equity Comp | 1.78M (0.09%) | -189.87K Decreased by -10.69% | Dec 31, 24 |
| 3 | Fidelity® Select Biotechnology | 1.69M (0.09%) | -147.50K Decreased by -8.74% | Nov 30, 23 |
| 4 | T. Rowe Price Health Sciences | 829.52K (0.04%) | -27.74K Decreased by -3.34% | Dec 31, 24 |
| 5 | Vanguard US Total Market Shares ETF | 461.05K (0.02%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 6 | Fidelity Select Biotechnology | 455.82K (0.02%) | -149.99K Decreased by -32.91% | Dec 31, 24 |
| 7 | Vanguard Total Stock Mkt Idx Inv | 448.61K (0.02%) | 0.00 Increased by 0.00% | May 31, 25 |
| 8 | T. Rowe Price New Horizons Tr-A | 426.94K (0.02%) | 30.79K Increased by +7.21% | Dec 31, 24 |
| 9 | T. Rowe Price New Horizons Tr-Z | 426.94K (0.02%) | 30.79K Increased by +7.21% | Dec 31, 24 |
| 10 | iShares Russell 2000 ETF | 386.57K (0.02%) | 0.00 Increased by 0.00% | May 31, 25 |
| 11 | Vanguard Institutional Extnd Mkt Idx Tr | 275.55K (0.01%) | 0.00 Increased by 0.00% | May 31, 25 |
| 12 | Invesco Dorsey Wright SmallCap Momt ETF | 224.31K (0.01%) | 406.00 Increased by +0.18% | Dec 31, 24 |
| 13 | State St Russell Sm/Mid Cp® Indx NL Cl C | 194.39K (0.01%) | 0.00 Increased by 0.00% | Apr 30, 25 |
| 14 | State St Russell Sm/Mid Cp® Indx SL Cl I | 194.39K (0.01%) | 0.00 Increased by 0.00% | May 31, 25 |
| 15 | Candriam Global Equities Oncology | 175.00K (0.01%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 16 | Fidelity Small Cap Index | 161.99K (0.01%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 17 | T. Rowe Price Integrated US Sm Gr Eq | 139.57K (0.01%) | 0.00 Increased by 0.00% | Oct 31, 24 |
| 18 | T. Rowe Price Integrated US SmCapGrEq | 139.57K (0.01%) | -3.58K Decreased by -2.56% | Sep 30, 24 |
| 19 | iShares Russell 2000 Value ETF | 127.15K (0.01%) | 0.00 Increased by 0.00% | May 29, 24 |
| 20 | Rhenman Healthcare Equity L/S RC2 SEK | 126.06K (0.01%) | 0.00 Increased by 0.00% | Dec 31, 24 |