| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Suvretta Capital Management, LLC | 7.93M (14.30%) | 1.45M Increased by +18.28% | Dec 31, 25 |
| 2 | 683 Capital Management LLC | 3.31M (5.97%) | 1.06M Increased by +32.13% | Dec 31, 25 |
| 3 | Bank of America Corp | 2.48M (4.46%) | 2.48M Increased by +100.00% | Sep 30, 25 |
| 4 | Point72 Asset Management, L.P. | 2.08M (3.75%) | 168.53K Increased by +8.10% | Sep 30, 23 |
| 5 | RA Capital Management, LLC | 1.97M (3.56%) | 1.97M Increased by +100.00% | Jun 30, 25 |
| 6 | Eversept Partners, LP | 1.73M (3.12%) | 90.20K Increased by +5.21% | Sep 30, 25 |
| 7 | Eversept Partners, LLC | 1.64M (2.96%) | -35.55K Decreased by -2.17% | Jun 30, 25 |
| 8 | Citigroup Inc | 1.20M (2.16%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 9 | SILVERARC CAPITAL MANAGEMENT, LLC | 1.16M (2.09%) | 1.16M Increased by +100.00% | Mar 31, 25 |
| 10 | TANG CAPITAL MANAGEMENT LLC | 769.07K (1.39%) | -2.06M Decreased by -267.25% | Mar 31, 24 |
| 11 | Woodline Partners LP | 751.27K (1.35%) | 283.00 Increased by +0.04% | Jun 30, 25 |
| 12 | StemPoint Capital LP | 725.02K (1.31%) | 725.02K Increased by +100.00% | Mar 31, 25 |
| 13 | Ikarian Capital, LLC | 722.07K (1.30%) | 17.06K Increased by +2.36% | Sep 30, 25 |
| 14 | Morgan Stanley - Brokerage Accounts | 626.60K (1.13%) | -67.25K Decreased by -10.73% | Sep 30, 25 |
| 15 | Northern Trust Corp | 618.90K (1.12%) | -47.94K Decreased by -7.75% | Mar 31, 25 |
| 16 | Two Sigma Investments LLC | 406.31K (0.73%) | 406.31K Increased by +100.00% | Dec 31, 25 |
| 17 | Raymond James Finl Svs Advisors, Inc. | 381.11K (0.69%) | 4.20K Increased by +1.10% | Sep 30, 24 |
| 18 | Adage Capital Partners Gp LLC | 331.11K (0.60%) | 331.11K Increased by +100.00% | Jun 30, 25 |
| 19 | Squarepoint Ops LLC | 324.35K (0.58%) | 135.83K Increased by +41.88% | Dec 31, 25 |
| 20 | Amvescap Plc. | 320.25K (0.58%) | 156.30K Increased by +48.80% | Dec 31, 23 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | A4Investments SICAV SIF ACCI IlanaA2EURH | 200.00K (0.36%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 2 | Invesco Raymond James SB-1 Equity ETF | 188.53K (0.34%) | 23.73K Increased by +12.58% | Feb 29, 24 |
| 3 | Lago Erie SICAV | 76.51K (0.14%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 4 | Vifag 2002 SICAV | 75.00K (0.14%) | 0.00 Increased by 0.00% | Dec 31, 25 |
| 5 | Goyer & Göppel Smart Sel Universal | 50.00K (0.09%) | 50.00K Increased by +100.00% | Jan 31, 26 |
| 6 | Fidelity Nasdaq Composite Index | 43.67K (0.08%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 7 | Alger LIfe Sciences Innovation Composite | 13.77K (0.02%) | 13.77K Increased by +100.00% | Feb 28, 25 |
| 8 | ETFMG Treatments Testing and Adv ETF | 13.06K (0.02%) | 0.00 Increased by 0.00% | Aug 30, 24 |
| 9 | Azimut Trend | 2.23K (0.00%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 10 | AZ Fd1 AZ Allc Global Agsv A-AZ USD C | 2.23K (0.00%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 11 | Azimut Trading | 244.00 (0.00%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 12 | Azimut Strategic Trend | 223.00 (0.00%) | 0.00 Increased by 0.00% | Sep 30, 25 |
| 13 | Blackstone Alternative Multi-Strategy I | 200.00 (0.00%) | 0.00 Increased by 0.00% | Mar 31, 24 |
| 14 | Azimut Scudo | 55.00 (0.00%) | 55.00 Increased by +100.00% | Jun 30, 25 |