| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Rubric Capital Management LP | 30.05M (22.47%) | 946.10K Increased by +3.15% | Dec 31, 25 |
| 2 | Clearline Capital LP | 12.24M (9.15%) | 2.52M Increased by +20.62% | Dec 31, 25 |
| 3 | Adage Capital Partners Gp LLC | 11.19M (8.36%) | 946.10K Increased by +8.46% | Dec 31, 25 |
| 4 | BlackRock Inc | 9.99M (7.47%) | -114.25K Decreased by -1.14% | Sep 30, 25 |
| 5 | Vanguard Group Inc | 9.82M (7.34%) | 1.36M Increased by +13.85% | Dec 31, 25 |
| 6 | Velan Capital Investment Management LP | 8.75M (6.54%) | 1.77M Increased by +20.18% | Sep 30, 25 |
| 7 | Baker Bros Advisors LP | 8.13M (6.08%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 8 | Orbimed Advisors, LLC | 6.51M (4.87%) | -3.60M Decreased by -55.25% | Jun 30, 24 |
| 9 | Franklin Resources Inc | 6.33M (4.73%) | -46.84K Decreased by -0.74% | Jun 30, 24 |
| 10 | Palisade Capital Management LLc | 6.33M (4.73%) | -1.00M Decreased by -15.83% | Dec 31, 25 |
| 11 | Point72 Asset Management, L.P. | 4.78M (3.57%) | 1.70M Increased by +35.60% | Mar 31, 25 |
| 12 | Great Point Partners LLC | 4.74M (3.54%) | 0.00 Increased by 0.00% | Sep 30, 23 |
| 13 | Tejara Capital Ltd | 4.59M (3.43%) | 72.30K Increased by +1.58% | Sep 30, 25 |
| 14 | State Street Corp | 3.65M (2.73%) | 189.24K Increased by +5.18% | Sep 30, 25 |
| 15 | Geode Capital Management, LLC | 3.64M (2.72%) | 76.17K Increased by +2.09% | Sep 30, 25 |
| 16 | TANG CAPITAL MANAGEMENT LLC | 3.45M (2.58%) | 1.31M Increased by +38.10% | Sep 30, 25 |
| 17 | JW Asset Management, LLC | 3.29M (2.46%) | 954.89K Increased by +29.00% | Sep 30, 25 |
| 18 | Millennium Management LLC | 3.17M (2.37%) | 1.93M Increased by +60.94% | Mar 31, 24 |
| 19 | Congress Park Capital LLC | 3.07M (2.29%) | 177.32K Increased by +5.78% | Dec 31, 25 |
| 20 | AIGH Capital Management, LLC | 3.01M (2.25%) | 231.06K Increased by +7.68% | Jun 30, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 5.47M (4.09%) | 413.70K Increased by +7.56% | Jan 31, 26 |
| 2 | Vanguard US Total Market Shares ETF | 4.68M (3.50%) | 0.00 Increased by 0.00% | Sep 30, 24 |
| 3 | Palisade Small Cap Core Equity | 4.36M (3.26%) | -307.54K Decreased by -7.05% | Dec 31, 25 |
| 4 | iShares Russell 2000 ETF | 3.81M (2.85%) | 1.69M Increased by +44.34% | Feb 28, 26 |
| 5 | SPDR® S&P Biotech ETF | 2.81M (2.10%) | 9.72K Increased by +0.35% | Aug 30, 24 |
| 6 | Franklin Biotechnology Discv A(acc)USD | 2.71M (2.02%) | -469.70K Decreased by -17.35% | Jul 31, 24 |
| 7 | Biotech Growth Ord | 2.58M (1.93%) | 2.58M Increased by +100.00% | Jun 30, 24 |
| 8 | Vanguard Institutional Extnd Mkt Idx Tr | 2.03M (1.52%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 9 | Franklin Small Cap Growth Adv | 1.80M (1.34%) | 0.00 Increased by 0.00% | Jul 31, 24 |
| 10 | Franklin Small Cap Growth SMA | 1.80M (1.34%) | 1.80M Increased by +99.99% | Mar 31, 24 |
| 11 | Franklin US Small Cap Growth Equity | 1.80M (1.34%) | 0.00 Increased by 0.00% | Jun 30, 24 |
| 12 | Fidelity Small Cap Index | 1.51M (1.13%) | -31.18K Decreased by -2.06% | Dec 31, 25 |
| 13 | Franklin Biotechnology Discovery A | 1.20M (0.89%) | 0.00 Increased by 0.00% | Jul 31, 24 |
| 14 | iShares Russell 2000 Value ETF | 1.15M (0.86%) | 1.15M Increased by +100.00% | Feb 28, 26 |
| 15 | Fidelity® Small Cap Index | 967.95K (0.72%) | 11.45K Increased by +1.18% | Oct 31, 23 |
| 16 | Fidelity Extended Market Index | 965.15K (0.72%) | -4.01K Decreased by -0.42% | Jan 31, 26 |
| 17 | Schwab US Small-Cap ETF™ | 884.07K (0.66%) | 780.00 Increased by +0.09% | Feb 28, 26 |
| 18 | State St Russell Sm/Mid Cp® Indx NL Cl C | 851.80K (0.64%) | 3.84K Increased by +0.45% | Apr 30, 25 |
| 19 | State St Russell Sm/Mid Cp® Indx SL Cl I | 836.30K (0.63%) | 0.00 Increased by 0.00% | Jan 31, 26 |
| 20 | Orchard Select Small Cap Value | 823.22K (0.62%) | -394.13K Decreased by -47.88% | Apr 30, 25 |