| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | RA Capital Management, LLC | 60.38M (11.31%) | 30.37M Increased by +50.30% | Mar 31, 25 |
| 2 | BlackRock Inc | 49.08M (9.19%) | -782.45K Decreased by -1.59% | Mar 31, 25 |
| 3 | RTW INVESTMENTS, LLC | 44.11M (8.26%) | 44.11M Increased by +100.00% | Sep 30, 24 |
| 4 | Deep Track Capital, LP | 38.18M (7.15%) | 34.16M Increased by +89.49% | Mar 31, 25 |
| 5 | Vanguard Group Inc | 34.15M (6.39%) | 608.03K Increased by +1.78% | Mar 31, 25 |
| 6 | State Street Corporation | 31.60M (5.92%) | 5.98M Increased by +18.92% | Mar 31, 24 |
| 7 | Vivo Capital, LLC | 27.23M (5.10%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 8 | State Street Corp | 23.91M (4.48%) | -3.25M Decreased by -13.58% | Mar 31, 25 |
| 9 | Holocene Advisors, LP | 22.20M (4.16%) | 4.02M Increased by +18.13% | Dec 31, 24 |
| 10 | Vestal Point Capital LP | 22.01M (4.12%) | 11.01M Increased by +50.01% | Mar 31, 25 |
| 11 | Adage Capital Partners Gp LLC | 21.80M (4.08%) | -7.08M Decreased by -32.45% | Dec 31, 24 |
| 12 | HHG PLC | 18.89M (3.54%) | -8.19M Decreased by -43.35% | Mar 31, 25 |
| 13 | TCG Crossover Management, LLC | 17.39M (3.26%) | -5.98M Decreased by -34.41% | Mar 31, 24 |
| 14 | Farallon Capital Management, L.L.C. | 16.84M (3.15%) | 9.34M Increased by +55.48% | Jun 30, 24 |
| 15 | Geode Capital Management, LLC | 13.57M (2.54%) | 426.08K Increased by +3.14% | Mar 31, 25 |
| 16 | Wellington Management Company LLP | 13.51M (2.53%) | 847.71K Increased by +6.27% | Dec 31, 24 |
| 17 | NEA Management Company, LLC | 12.78M (2.39%) | -10.00M Decreased by -78.27% | Mar 31, 24 |
| 18 | FMR Inc | 12.37M (2.32%) | -1.97M Decreased by -15.91% | Mar 31, 25 |
| 19 | Morgan Stanley - Brokerage Accounts | 11.53M (2.16%) | -153.10K Decreased by -1.33% | Mar 31, 25 |
| 20 | Millennium Management LLC | 10.81M (2.02%) | 3.77M Increased by +34.90% | Mar 31, 25 |
| Rank | Holder | SharesFloat % | Change | Date reported |
|---|---|---|---|---|
| 1 | Vanguard Total Stock Mkt Idx Inv | 19.66M (3.68%) | 0.00 Increased by 0.00% | Jun 30, 25 |
| 2 | Vanguard US Total Market Shares ETF | 17.83M (3.34%) | 17.67K Increased by +0.10% | Sep 30, 24 |
| 3 | iShares Russell 2000 ETF | 14.15M (2.65%) | -268.90K Decreased by -1.90% | Jul 31, 25 |
| 4 | BioPharma Credit Ord | 14.12M (2.64%) | 14.12M Increased by +100.00% | Dec 31, 24 |
| 5 | SPDR® S&P Biotech ETF | 10.09M (1.89%) | 302.04K Increased by +2.99% | Jul 31, 25 |
| 6 | Vanguard Explorer Inv | 8.92M (1.67%) | 3.12M Increased by +35.02% | Jun 30, 25 |
| 7 | Vanguard Institutional Extnd Mkt Idx Tr | 8.75M (1.64%) | 458.79K Increased by +5.24% | Jun 30, 25 |
| 8 | Eventide Healthcare & Life Sciences I | 7.07M (1.32%) | 0.00 Increased by 0.00% | Mar 31, 25 |
| 9 | Fidelity Small Cap Index | 6.01M (1.12%) | -5.72K Decreased by -0.10% | May 31, 25 |
| 10 | iShares Russell 2000 Growth ETF | 5.28M (0.99%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 11 | Fidelity® Small Cap Index | 4.81M (0.90%) | 131.18K Increased by +2.73% | Oct 31, 23 |
| 12 | Fidelity Select Biotechnology | 4.70M (0.88%) | 2.63M Increased by +55.93% | Jun 30, 25 |
| 13 | abrdn Healthcare Investors | 4.63M (0.87%) | 895.96K Increased by +19.36% | Jun 30, 25 |
| 14 | Fidelity Growth Compy Commingled Pl O | 4.29M (0.80%) | 0.00 Increased by 0.00% | Aug 31, 24 |
| 15 | ClearBridge Small Cap Growth | 3.77M (0.71%) | 1.68M Increased by +44.69% | Jun 30, 25 |
| 16 | ClearBridge Small Cap Growth A | 3.77M (0.71%) | 1.68M Increased by +44.69% | Jun 30, 25 |
| 17 | iShares Biotechnology ETF | 3.72M (0.70%) | 31.80K Increased by +0.85% | Jul 31, 25 |
| 18 | State St Russell Sm/Mid Cp® Indx NL Cl C | 3.47M (0.65%) | 14.43K Increased by +0.42% | Apr 30, 25 |
| 19 | State St Russell Sm/Mid Cp® Indx SL Cl I | 3.45M (0.65%) | 0.00 Increased by 0.00% | Jul 31, 25 |
| 20 | Fidelity Growth Company Fund | 3.43M (0.64%) | 0.00 Increased by 0.00% | Mar 31, 25 |